NO20080125L - 2,6-kinolinylderivater, fremgangsmater for fremstilling derav og deres anvendelse som medikament - Google Patents
2,6-kinolinylderivater, fremgangsmater for fremstilling derav og deres anvendelse som medikamentInfo
- Publication number
- NO20080125L NO20080125L NO20080125A NO20080125A NO20080125L NO 20080125 L NO20080125 L NO 20080125L NO 20080125 A NO20080125 A NO 20080125A NO 20080125 A NO20080125 A NO 20080125A NO 20080125 L NO20080125 L NO 20080125L
- Authority
- NO
- Norway
- Prior art keywords
- processes
- preparation
- medicament
- quinolinyl derivatives
- diseases including
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
- A61K31/4709—Non-condensed quinolines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/04—Antipruritics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P17/00—Drugs for dermatological disorders
- A61P17/06—Antipsoriatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/16—Otologicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Immunology (AREA)
- Dermatology (AREA)
- Pulmonology (AREA)
- Rheumatology (AREA)
- Oncology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Transplantation (AREA)
- Pain & Pain Management (AREA)
- Urology & Nephrology (AREA)
- Ophthalmology & Optometry (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Hematology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Foreliggende oppfinnelse angår 2,6-kinolinylderivater, fremgangsmåter for fremstilling av disse, farma- søytiske preparater inneholdende dem og deres anvendelse som farmasøytiske midler. Eksempelvis er forbindelsene ifølge oppflnnelsen anvendbare for behandling av astma, allergisk rhinitt, sinusitt, konjunktivitt, matallergi, inflammatoriske hudsykdommer innbefattende dermatitt, psoriasis, urticaria, pruritus og eksem, reumatoid artritt, inflammatoriske tarmsykdommer innbefattende Crohns sykdom og ulcerøs kolitt, multippel sklerose og andre autoimmune sykdommer, og aterosklerose.
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB0511781A GB0511781D0 (en) | 2005-06-09 | 2005-06-09 | 2,6-quinolinyl derivatives, processes for preparing them and their uses |
US20615805A | 2005-08-18 | 2005-08-18 | |
GB0600213A GB0600213D0 (en) | 2006-01-06 | 2006-01-06 | 2,6-quinolinyl derivatives, processes for preparing them and their uses |
PCT/EP2006/004811 WO2006131200A1 (en) | 2005-06-09 | 2006-05-22 | 2,6 quinolinyl derivatives, processes for preparing them and their use as medicament |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20080125L true NO20080125L (no) | 2008-01-08 |
Family
ID=36968449
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20080125A NO20080125L (no) | 2005-06-09 | 2008-01-08 | 2,6-kinolinylderivater, fremgangsmater for fremstilling derav og deres anvendelse som medikament |
Country Status (19)
Country | Link |
---|---|
US (1) | US7732614B2 (no) |
EP (1) | EP1902045B1 (no) |
JP (1) | JP2008542407A (no) |
KR (1) | KR20080021085A (no) |
AR (1) | AR054129A1 (no) |
AT (1) | ATE496041T1 (no) |
AU (1) | AU2006254772B2 (no) |
BR (1) | BRPI0611243A2 (no) |
CA (1) | CA2610800A1 (no) |
DE (1) | DE602006019731D1 (no) |
EA (1) | EA013080B1 (no) |
IL (1) | IL187235A0 (no) |
MX (1) | MX2007014721A (no) |
MY (1) | MY140739A (no) |
NO (1) | NO20080125L (no) |
NZ (1) | NZ563739A (no) |
PE (1) | PE20070081A1 (no) |
TW (1) | TW200716605A (no) |
WO (1) | WO2006131200A1 (no) |
Families Citing this family (16)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PL373763A1 (en) | 2002-04-30 | 2005-09-19 | Ucb, S.A. | 2,6-quinolinyl and 2,6-naphthyl derivatives, processes for preparing them and their uses as vla-4 inhibitors |
CA2478458A1 (en) * | 2004-08-20 | 2006-02-20 | Michael Panzara | Treatment of pediatric multiple sclerosis |
AU2005306399B2 (en) * | 2004-11-19 | 2012-02-09 | Biogen Ma Inc. | Treatment for multiple sclerosis |
CA2610800A1 (en) | 2005-06-09 | 2006-12-14 | Ucb Pharma, S.A. | 2,6 quinolinyl derivatives, processes for preparing them and their use as medicament |
WO2008125215A1 (en) * | 2007-04-12 | 2008-10-23 | Ucb Pharma, S.A. | Bicyclic and heterobicyclic derivatives, processes for preparing them and their uses |
CA2758548A1 (en) * | 2009-04-17 | 2010-10-21 | Biogen Idec Ma Inc. | Compositions and methods to treat acute myelogenous leukemia |
HUE035098T2 (en) | 2010-04-16 | 2018-05-02 | Biogen Ma Inc | Anti-VLA4 Antibodies |
MY160723A (en) * | 2013-12-30 | 2017-03-15 | Univ Putra Malaysia | An anticoagulant |
USD812958S1 (en) | 2016-06-08 | 2018-03-20 | Samsung Electronics Co., Ltd. | Cooktop |
WO2019200202A1 (en) | 2018-04-12 | 2019-10-17 | Morphic Therapeutic, Inc. | Antagonists of human integrin (alpha4)(beta7) |
WO2020092401A1 (en) * | 2018-10-30 | 2020-05-07 | Gilead Sciences, Inc. | COMPOUNDS FOR INHIBITION OF ALPHA 4β7 INTEGRIN |
CA3114240C (en) | 2018-10-30 | 2023-09-05 | Gilead Sciences, Inc. | Imidazopyridine derivatives as alpha4beta7 integrin inhibitors |
US11224600B2 (en) | 2018-10-30 | 2022-01-18 | Gilead Sciences, Inc. | Compounds for inhibition of alpha 4 beta 7 integrin |
EP3873884A1 (en) * | 2018-10-30 | 2021-09-08 | Gilead Sciences, Inc. | Quinoline derivatives as alpha4beta7 integrin inhibitors |
JP7491996B2 (ja) | 2019-08-14 | 2024-05-28 | ギリアード サイエンシーズ, インコーポレイテッド | α4β7インテグリンの阻害のための化合物 |
KR20220102669A (ko) | 2019-10-16 | 2022-07-20 | 모픽 테라퓨틱, 인코포레이티드 | 인간 인테그린 α4β7의 억제 |
Family Cites Families (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1996018606A1 (fr) | 1994-12-14 | 1996-06-20 | Santen Pharmaceutical Co., Ltd. | Nouveaux derives 1,3-dialkyluree |
HU229362B1 (en) | 1997-08-22 | 2013-11-28 | Hoffmann La Roche | N-alkanoylphenylalanine derivatives |
EP1114028B1 (en) | 1998-08-26 | 2006-11-29 | Aventis Pharma Limited | Aza-bicycles which modulate the inhibition of cell adhesion |
MXPA01010916A (es) | 1999-04-28 | 2002-06-21 | Reddy Research Foundation | Heterociclos biciclicos sustituidos, procedimiento para su preparacion y su uso como agentes contra la obesidad y como agentes hipocolesterolemicos. |
MY129000A (en) | 2000-08-31 | 2007-03-30 | Tanabe Seiyaku Co | INHIBITORS OF a4 MEDIATED CELL ADHESION |
MY140707A (en) | 2002-02-28 | 2010-01-15 | Mitsubishi Tanabe Pharma Corp | Process for preparing a phenylalanine derivative and intermediates thereof |
PL373763A1 (en) * | 2002-04-30 | 2005-09-19 | Ucb, S.A. | 2,6-quinolinyl and 2,6-naphthyl derivatives, processes for preparing them and their uses as vla-4 inhibitors |
US7153870B2 (en) * | 2003-07-25 | 2006-12-26 | Pfizer Inc. | Nicotinamide derivatives useful as PDE4 inhibitors |
GB0329584D0 (en) | 2003-12-20 | 2004-01-28 | Tanabe Seiyaku Co | Novel compounds |
CA2610800A1 (en) | 2005-06-09 | 2006-12-14 | Ucb Pharma, S.A. | 2,6 quinolinyl derivatives, processes for preparing them and their use as medicament |
-
2006
- 2006-05-22 CA CA002610800A patent/CA2610800A1/en not_active Abandoned
- 2006-05-22 WO PCT/EP2006/004811 patent/WO2006131200A1/en active Application Filing
- 2006-05-22 EP EP06753758A patent/EP1902045B1/en active Active
- 2006-05-22 DE DE602006019731T patent/DE602006019731D1/de active Active
- 2006-05-22 EA EA200702589A patent/EA013080B1/ru not_active IP Right Cessation
- 2006-05-22 AT AT06753758T patent/ATE496041T1/de not_active IP Right Cessation
- 2006-05-22 MY MYPI20062356A patent/MY140739A/en unknown
- 2006-05-22 MX MX2007014721A patent/MX2007014721A/es active IP Right Grant
- 2006-05-22 BR BRPI0611243-9A patent/BRPI0611243A2/pt not_active IP Right Cessation
- 2006-05-22 JP JP2008515081A patent/JP2008542407A/ja active Pending
- 2006-05-22 KR KR1020077031009A patent/KR20080021085A/ko not_active Application Discontinuation
- 2006-05-22 AR ARP060102077A patent/AR054129A1/es not_active Application Discontinuation
- 2006-05-22 AU AU2006254772A patent/AU2006254772B2/en not_active Ceased
- 2006-05-22 NZ NZ563739A patent/NZ563739A/en not_active IP Right Cessation
- 2006-06-02 PE PE2006000596A patent/PE20070081A1/es not_active Application Discontinuation
- 2006-06-05 TW TW095119798A patent/TW200716605A/zh unknown
- 2006-06-09 US US11/450,694 patent/US7732614B2/en not_active Expired - Fee Related
-
2007
- 2007-11-08 IL IL187235A patent/IL187235A0/en unknown
-
2008
- 2008-01-08 NO NO20080125A patent/NO20080125L/no not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
JP2008542407A (ja) | 2008-11-27 |
AR054129A1 (es) | 2007-06-06 |
KR20080021085A (ko) | 2008-03-06 |
PE20070081A1 (es) | 2007-02-15 |
IL187235A0 (en) | 2008-02-09 |
EA200702589A1 (ru) | 2008-06-30 |
CA2610800A1 (en) | 2006-12-14 |
EA013080B1 (ru) | 2010-02-26 |
WO2006131200A1 (en) | 2006-12-14 |
NZ563739A (en) | 2009-12-24 |
MY140739A (en) | 2010-01-15 |
EP1902045B1 (en) | 2011-01-19 |
MX2007014721A (es) | 2008-02-14 |
TW200716605A (en) | 2007-05-01 |
DE602006019731D1 (de) | 2011-03-03 |
ATE496041T1 (de) | 2011-02-15 |
US7732614B2 (en) | 2010-06-08 |
BRPI0611243A2 (pt) | 2010-08-24 |
US20070004775A1 (en) | 2007-01-04 |
AU2006254772A1 (en) | 2006-12-14 |
EP1902045A1 (en) | 2008-03-26 |
AU2006254772B2 (en) | 2011-06-02 |
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Legal Events
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |