NO20082604L - Cinnamidforbindelse av morfolintype - Google Patents
Cinnamidforbindelse av morfolintypeInfo
- Publication number
- NO20082604L NO20082604L NO20082604A NO20082604A NO20082604L NO 20082604 L NO20082604 L NO 20082604L NO 20082604 A NO20082604 A NO 20082604A NO 20082604 A NO20082604 A NO 20082604A NO 20082604 L NO20082604 L NO 20082604L
- Authority
- NO
- Norway
- Prior art keywords
- group
- morpholine
- atom
- compound
- cinnamide compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2005337952 | 2005-11-24 | ||
| JP2006205591 | 2006-07-28 | ||
| PCT/JP2006/321473 WO2007060810A1 (ja) | 2005-11-24 | 2006-10-27 | モルホリンタイプ・シンナミド化合物 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NO20082604L true NO20082604L (no) | 2008-08-21 |
Family
ID=38054331
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20082604A NO20082604L (no) | 2005-11-24 | 2008-06-11 | Cinnamidforbindelse av morfolintype |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US7618960B2 (ja) |
| EP (1) | EP1953154A4 (ja) |
| JP (1) | JP5221144B2 (ja) |
| KR (1) | KR20080069221A (ja) |
| AR (1) | AR058198A1 (ja) |
| AU (1) | AU2006317457B2 (ja) |
| BR (1) | BRPI0618814A2 (ja) |
| CA (1) | CA2629745A1 (ja) |
| HK (1) | HK1122807A1 (ja) |
| MY (1) | MY144960A (ja) |
| NO (1) | NO20082604L (ja) |
| NZ (1) | NZ568050A (ja) |
| PE (1) | PE20070646A1 (ja) |
| RU (1) | RU2381225C1 (ja) |
| SA (1) | SA06270431B1 (ja) |
| TW (1) | TWI386207B (ja) |
| WO (1) | WO2007060810A1 (ja) |
Families Citing this family (55)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR101128065B1 (ko) | 2004-05-26 | 2012-04-12 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 신나미드 화합물 |
| US7923563B2 (en) | 2004-10-26 | 2011-04-12 | Eisai R&D Management Co., Ltd. | Amorphous object of cinnamide compound |
| AU2006316005A1 (en) * | 2005-11-18 | 2007-05-24 | Eisai R & D Management Co., Ltd. | Process for production of cinnamamide derivative |
| JPWO2007058304A1 (ja) * | 2005-11-18 | 2009-05-07 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | シンナミド化合物の塩またはそれらの溶媒和物 |
| JP5221144B2 (ja) | 2005-11-24 | 2013-06-26 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | モルホリンタイプ・シンナミド化合物 |
| TWI370130B (en) | 2005-11-24 | 2012-08-11 | Eisai R&D Man Co Ltd | Two cyclic cinnamide compound |
| TWI378091B (en) | 2006-03-09 | 2012-12-01 | Eisai R&D Man Co Ltd | Multi-cyclic cinnamide derivatives |
| KR20090016591A (ko) * | 2006-05-19 | 2009-02-16 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 헤테로사이클 타입의 신나미드 유도체 |
| AU2007252643A1 (en) * | 2006-05-19 | 2007-11-29 | Eisai R & D Management Co., Ltd. | Urea type cinnamide derivative |
| US7737141B2 (en) | 2006-07-28 | 2010-06-15 | Eisai R&D Management Co., Ltd. | Prodrug of cinnamide compound |
| CA2677296A1 (en) * | 2007-02-08 | 2008-08-14 | Merck & Co., Inc. | Therapeutic agents |
| US20080207900A1 (en) | 2007-02-28 | 2008-08-28 | Teiji Kimura | Two cyclic oxomorphorin derivatives |
| DE102007009810A1 (de) * | 2007-02-28 | 2008-09-04 | Man Roland Druckmaschinen Ag | Übertragungsform für einen Übertragungszylinder einer Druckmaschine |
| ES2358863T3 (es) * | 2007-05-11 | 2011-05-16 | F. Hoffmann-La Roche Ag | Hetarilanilinas como moduladores de beta-amiloide. |
| AU2008250119A1 (en) * | 2007-05-16 | 2008-11-20 | Eisai R & D Management Co., Ltd. | One-pot production process for cinnamide derivative |
| AU2008263206A1 (en) * | 2007-06-01 | 2008-12-18 | Schering Corporation | Gamma secretase modulators |
| KR20100037053A (ko) * | 2007-06-01 | 2010-04-08 | 쉐링 코포레이션 | 감마 세크레타제 조절인자 |
| EP2166854A4 (en) * | 2007-06-13 | 2012-05-16 | Merck Sharp & Dohme | TRIAZOLE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND ASSOCIATED STATES |
| CA2692253A1 (en) * | 2007-06-29 | 2009-01-08 | Schering Corporation | Gamma secretase modulators |
| EP2185522A1 (en) * | 2007-08-06 | 2010-05-19 | Schering Corporation | Gamma secretase modulators |
| CA2695864A1 (en) * | 2007-08-07 | 2009-02-12 | Schering Corporation | Gamma secretase modulators |
| CA2694401C (en) | 2007-08-31 | 2012-12-04 | Eisai R&D Management Co., Ltd. | Polycyclic compound |
| US7935815B2 (en) | 2007-08-31 | 2011-05-03 | Eisai R&D Management Co., Ltd. | Imidazoyl pyridine compounds and salts thereof |
| WO2009032277A1 (en) | 2007-09-06 | 2009-03-12 | Schering Corporation | Gamma secretase modulators |
| US20100298381A1 (en) * | 2007-09-28 | 2010-11-25 | Schering Corporation | Gamma secretase modulators |
| US8487099B2 (en) | 2007-11-05 | 2013-07-16 | Merck Sharp & Dohme Corp. | Gamma secretase modulators |
| MX2010006378A (es) * | 2007-12-11 | 2010-09-07 | Schering Corp | Moduladores de gamma secretasa. |
| CA2708151A1 (en) * | 2007-12-11 | 2009-06-18 | Schering Corporation | Gamma secretase modulators |
| JP5395808B2 (ja) * | 2007-12-21 | 2014-01-22 | エフ．ホフマン−ラ ロシュ アーゲー | オレキシン受容体アンタゴニストとしてのヘテロアリール誘導体 |
| KR101244517B1 (ko) * | 2008-01-11 | 2013-03-18 | 에프. 호프만-라 로슈 아게 | 아밀로이드 베타에 대한 조절제 |
| CA2712095A1 (en) * | 2008-01-28 | 2009-08-06 | Eisai R&D Management Co., Ltd. | Crystalline cinnamide compounds or salts thereof |
| MX2010008700A (es) * | 2008-02-22 | 2010-08-30 | Hoffmann La Roche | Moduladores de beta-amiloide. |
| WO2009108766A1 (en) * | 2008-02-29 | 2009-09-03 | Schering Corporation | Gamma secretase modulators for the treatment of alzheimer ' s disease |
| AU2009301210B2 (en) * | 2008-10-09 | 2014-05-15 | F. Hoffmann-La Roche Ag | Modulators for amyloid beta |
| WO2010054064A1 (en) * | 2008-11-06 | 2010-05-14 | Schering Corporation | Gamma secretase modulators |
| JP2012508182A (ja) * | 2008-11-06 | 2012-04-05 | シェーリング コーポレイション | γ−セクレターゼ調節剤 |
| MX2011004954A (es) | 2008-11-10 | 2011-05-30 | Hoffmann La Roche | Moduladores heterociclicos de gamma-secretasa. |
| CA2742486A1 (en) | 2008-11-13 | 2010-05-20 | Schering Corporation | Gamma secretase modulators |
| WO2010056722A1 (en) * | 2008-11-13 | 2010-05-20 | Schering Corporation | Gamma secretase modulators |
| WO2010071741A1 (en) | 2008-12-16 | 2010-06-24 | Merck Sharp & Dohme Corp. | Triazole derivatives for treatment of alzheimer's disease |
| TW201034666A (en) | 2008-12-22 | 2010-10-01 | Schering Corp | Gamma secretase modulators |
| CA2747750A1 (en) | 2008-12-22 | 2010-07-01 | Theodros Asberom | Gamma secretase modulators |
| MX2011006782A (es) | 2009-02-26 | 2011-07-20 | Eisai R&D Man Co Ltd | Sal de derivado de tetrahidrotriazolopiridina y un cristal de la misma. |
| MX2011008501A (es) | 2009-02-26 | 2011-09-01 | Eisai R&D Man Co Ltd | Compuestos heterociclicos fusionados que contienen nitrogeno y su uso como inhibidores de la produccion de beta-amiloide. |
| EP2443118A1 (en) | 2009-06-16 | 2012-04-25 | Schering Corporation | Gamma secretase modulators |
| EP2443121A2 (en) | 2009-06-16 | 2012-04-25 | Schering Corporation | Gamma secretase modulators |
| US20120245158A1 (en) | 2009-06-16 | 2012-09-27 | Xianhai Huang | Gamma secretase modulators |
| JP2012176901A (ja) * | 2009-09-25 | 2012-09-13 | Eisai R & D Management Co Ltd | 新規ベンゾニトリル化合物およびその製造方法 |
| US20110190269A1 (en) * | 2010-02-01 | 2011-08-04 | Karlheinz Baumann | Gamma secretase modulators |
| US8486967B2 (en) | 2010-02-17 | 2013-07-16 | Hoffmann-La Roche Inc. | Heteroaryl substituted piperidines |
| CA2830027C (en) | 2011-03-31 | 2016-04-26 | Pfizer Inc. | Novel bicyclic pyridinones |
| CN102675240B (zh) | 2012-04-13 | 2015-01-14 | 浙江海正药业股份有限公司 | 4-取代基-2-羟基吗啉-3-酮及其制备方法 |
| UA110688C2 (uk) | 2012-09-21 | 2016-01-25 | Пфайзер Інк. | Біциклічні піридинони |
| EP3253755B1 (en) | 2015-02-03 | 2020-08-26 | Pfizer Inc | Novel cyclopropabenzofuranyl pyridopyrazinediones |
| JP6807941B2 (ja) | 2016-02-29 | 2021-01-06 | バイオ−ファーム ソリューションズ カンパニー リミテッド | スルファメート誘導体化合物、その製造方法および用途 |
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| JP5221144B2 (ja) | 2005-11-24 | 2013-06-26 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | モルホリンタイプ・シンナミド化合物 |
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| CA2677296A1 (en) | 2007-02-08 | 2008-08-14 | Merck & Co., Inc. | Therapeutic agents |
| JP5209043B2 (ja) | 2007-05-07 | 2013-06-12 | メルク・シャープ・アンド・ドーム・コーポレーション | ガンマセクレターゼ調節剤 |
| ES2358863T3 (es) | 2007-05-11 | 2011-05-16 | F. Hoffmann-La Roche Ag | Hetarilanilinas como moduladores de beta-amiloide. |
| EP2166854A4 (en) | 2007-06-13 | 2012-05-16 | Merck Sharp & Dohme | TRIAZOLE DERIVATIVES FOR THE TREATMENT OF ALZHEIMER'S DISEASE AND ASSOCIATED STATES |
| EP2185522A1 (en) | 2007-08-06 | 2010-05-19 | Schering Corporation | Gamma secretase modulators |
-
2006
- 2006-10-27 JP JP2007546382A patent/JP5221144B2/ja not_active Expired - Fee Related
- 2006-10-27 BR BRPI0618814-1A patent/BRPI0618814A2/pt not_active IP Right Cessation
- 2006-10-27 MY MYPI20081694A patent/MY144960A/en unknown
- 2006-10-27 WO PCT/JP2006/321473 patent/WO2007060810A1/ja active Application Filing
- 2006-10-27 CA CA002629745A patent/CA2629745A1/en not_active Abandoned
- 2006-10-27 KR KR1020087013158A patent/KR20080069221A/ko active IP Right Grant
- 2006-10-27 RU RU2008125426/04A patent/RU2381225C1/ru not_active IP Right Cessation
- 2006-10-27 TW TW095139716A patent/TWI386207B/zh not_active IP Right Cessation
- 2006-10-27 AU AU2006317457A patent/AU2006317457B2/en not_active Ceased
- 2006-10-27 NZ NZ568050A patent/NZ568050A/en not_active IP Right Cessation
- 2006-10-27 EP EP06832397.1A patent/EP1953154A4/en not_active Withdrawn
- 2006-11-08 US US11/594,130 patent/US7618960B2/en not_active Expired - Fee Related
- 2006-11-20 AR ARP060105074A patent/AR058198A1/es not_active Application Discontinuation
- 2006-11-21 PE PE2006001480A patent/PE20070646A1/es not_active Application Discontinuation
- 2006-11-22 SA SA06270431A patent/SA06270431B1/ar unknown
-
2008
- 2008-06-11 NO NO20082604A patent/NO20082604L/no not_active Application Discontinuation
- 2008-12-29 HK HK08114016.3A patent/HK1122807A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| US7618960B2 (en) | 2009-11-17 |
| AR058198A1 (es) | 2008-01-23 |
| EP1953154A4 (en) | 2013-11-20 |
| NZ568050A (en) | 2010-09-30 |
| KR20080069221A (ko) | 2008-07-25 |
| MY144960A (en) | 2011-11-30 |
| WO2007060810A1 (ja) | 2007-05-31 |
| AU2006317457B2 (en) | 2011-09-08 |
| PE20070646A1 (es) | 2007-07-30 |
| JPWO2007060810A1 (ja) | 2009-05-07 |
| BRPI0618814A2 (pt) | 2014-04-29 |
| TW200730514A (en) | 2007-08-16 |
| RU2381225C1 (ru) | 2010-02-10 |
| HK1122807A1 (en) | 2009-05-29 |
| AU2006317457A1 (en) | 2007-05-31 |
| JP5221144B2 (ja) | 2013-06-26 |
| CA2629745A1 (en) | 2007-05-31 |
| SA06270431B1 (ar) | 2010-07-03 |
| EP1953154A1 (en) | 2008-08-06 |
| US20070117798A1 (en) | 2007-05-24 |
| TWI386207B (zh) | 2013-02-21 |
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