US3547119A
(en)
|
1967-12-08 |
1970-12-15 |
Baxter Laboratories Inc |
Catheter assembly
|
US3798209A
(en)
*
|
1971-06-01 |
1974-03-19 |
Icn Pharmaceuticals |
1,2,4-triazole nucleosides
|
US4211771A
(en)
|
1971-06-01 |
1980-07-08 |
Robins Ronald K |
Treatment of human viral diseases with 1-B-D-ribofuranosyl-1,2,4-triazole-3-carboxamide
|
US4311137A
(en)
|
1980-04-30 |
1982-01-19 |
Sherwood Medical Industries Inc. |
Infusion device
|
US4531937A
(en)
|
1983-01-24 |
1985-07-30 |
Pacesetter Systems, Inc. |
Introducer catheter apparatus and method of use
|
CS263951B1
(en)
*
|
1985-04-25 |
1989-05-12 |
Antonin Holy |
9-(phosponylmethoxyalkyl)adenines and method of their preparation
|
NZ216172A
(en)
|
1985-05-15 |
1989-08-29 |
Wellcome Found |
Nucleosides and pharmaceutical compositions
|
US4806347A
(en)
|
1985-12-11 |
1989-02-21 |
Schering Corporation |
Interferon combinations
|
US4755173A
(en)
|
1986-02-25 |
1988-07-05 |
Pacesetter Infusion, Ltd. |
Soft cannula subcutaneous injection set
|
CS264222B1
(en)
*
|
1986-07-18 |
1989-06-13 |
Holy Antonin |
N-phosphonylmethoxyalkylderivatives of bases of pytimidine and purine and method of use them
|
US5082659A
(en)
|
1986-10-06 |
1992-01-21 |
Board Of Regents, The University Of Texas System |
Methods and compositions employing interferon-gamma
|
US5190751A
(en)
|
1987-01-20 |
1993-03-02 |
Schering Corporation |
Treatment of certain leukemias with a combination of gamma interferon and alpha interferon
|
ATE74517T1
(de)
|
1987-01-20 |
1992-04-15 |
Schering Corp |
Behandlung von einigen leukaemien mit einer zusammensetzung von interferon-gamma und interferon-alpha.
|
WO1988009673A1
(en)
|
1987-06-02 |
1988-12-15 |
Schering Corporation |
Treatment of chronic type b hepatitis with a combination of recombinant human alpha and gamma interferons
|
GB8815265D0
(en)
*
|
1988-06-27 |
1988-08-03 |
Wellcome Found |
Therapeutic nucleosides
|
US5696270A
(en)
*
|
1989-05-23 |
1997-12-09 |
Abbott Laboratories |
Intermediate for making retroviral protease inhibiting compounds
|
US5232928A
(en)
|
1989-07-25 |
1993-08-03 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Tetrahydroisoquinoline amides
|
US5518729A
(en)
|
1989-11-22 |
1996-05-21 |
Margolin; Solomon B. |
Compositions and methods for reparation and prevention of fibrotic lesions
|
US5716632A
(en)
|
1989-11-22 |
1998-02-10 |
Margolin; Solomon B. |
Compositions and methods for reparation and prevention of fibrotic lesions
|
US5310562A
(en)
|
1989-11-22 |
1994-05-10 |
Margolin Solomon B |
Composition and method for reparation and prevention of fibrotic lesions
|
US5372808A
(en)
|
1990-10-17 |
1994-12-13 |
Amgen Inc. |
Methods and compositions for the treatment of diseases with consensus interferon while reducing side effect
|
US5610054A
(en)
|
1992-05-14 |
1997-03-11 |
Ribozyme Pharmaceuticals, Inc. |
Enzymatic RNA molecule targeted against Hepatitis C virus
|
US5382657A
(en)
|
1992-08-26 |
1995-01-17 |
Hoffmann-La Roche Inc. |
Peg-interferon conjugates
|
US5545143A
(en)
|
1993-01-21 |
1996-08-13 |
T. S. I. Medical |
Device for subcutaneous medication delivery
|
PT730470E
(pt)
|
1993-11-10 |
2002-08-30 |
Enzon Inc |
Conjugados melhorados de interferao-polimero
|
US5624949A
(en)
|
1993-12-07 |
1997-04-29 |
Eli Lilly And Company |
Protein kinase C inhibitors
|
US6693072B2
(en)
|
1994-06-02 |
2004-02-17 |
Aventis Pharmaceuticals Inc. |
Elastase inhibitors
|
US5500208A
(en)
|
1994-06-07 |
1996-03-19 |
The Procter & Gamble Company |
Oral compositions comprising a novel tripeptide
|
US5756466A
(en)
|
1994-06-17 |
1998-05-26 |
Vertex Pharmaceuticals, Inc. |
Inhibitors of interleukin-1β converting enzyme
|
US5847135A
(en)
|
1994-06-17 |
1998-12-08 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of interleukin-1β converting enzyme
|
US5824784A
(en)
|
1994-10-12 |
1998-10-20 |
Amgen Inc. |
N-terminally chemically modified protein compositions and methods
|
IL116730A0
(en)
|
1995-01-13 |
1996-05-14 |
Amgen Inc |
Chemically modified interferon
|
US6090822A
(en)
|
1995-03-03 |
2000-07-18 |
Margolin; Solomon B. |
Treatment of cytokine growth factor caused disorders
|
GB9517022D0
(en)
|
1995-08-19 |
1995-10-25 |
Glaxo Group Ltd |
Medicaments
|
US5908621A
(en)
|
1995-11-02 |
1999-06-01 |
Schering Corporation |
Polyethylene glycol modified interferon therapy
|
US5980884A
(en)
|
1996-02-05 |
1999-11-09 |
Amgen, Inc. |
Methods for retreatment of patients afflicted with Hepatitis C using consensus interferon
|
US5908121A
(en)
|
1996-03-11 |
1999-06-01 |
Dardashti; Shahriar |
Adjustable display assembly
|
US5633388A
(en)
|
1996-03-29 |
1997-05-27 |
Viropharma Incorporated |
Compounds, compositions and methods for treatment of hepatitis C
|
EP0907659A1
(de)
|
1996-05-10 |
1999-04-14 |
Schering Corporation |
Hepatitis c virus ns3 protease synthetische inhibitoren
|
ZA979327B
(en)
|
1996-10-18 |
1998-05-11 |
Vertex Pharma |
Inhibitors of serine proteases, particularly hepatitis C virus NS3 protease.
|
GB9623908D0
(en)
|
1996-11-18 |
1997-01-08 |
Hoffmann La Roche |
Amino acid derivatives
|
US5968895A
(en)
|
1996-12-11 |
1999-10-19 |
Praecis Pharmaceuticals, Inc. |
Pharmaceutical formulations for sustained drug delivery
|
WO1998046597A1
(en)
|
1997-04-14 |
1998-10-22 |
Emory University |
Serine protease inhibitors
|
GB9707659D0
(en)
|
1997-04-16 |
1997-06-04 |
Peptide Therapeutics Ltd |
Hepatitis C NS3 Protease inhibitors
|
US6767991B1
(en)
|
1997-08-11 |
2004-07-27 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis C inhibitor peptides
|
ATE291032T1
(de)
|
1997-08-11 |
2005-04-15 |
Boehringer Ingelheim Ca Ltd |
Hepatitis c inhibitor peptide
|
CA2294562C
(en)
|
1997-08-11 |
2005-07-26 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor peptide analogues
|
US6172046B1
(en)
|
1997-09-21 |
2001-01-09 |
Schering Corporation |
Combination therapy for eradicating detectable HCV-RNA in patients having chronic Hepatitis C infection
|
US5985263A
(en)
|
1997-12-19 |
1999-11-16 |
Enzon, Inc. |
Substantially pure histidine-linked protein polymer conjugates
|
IT1299134B1
(it)
|
1998-02-02 |
2000-02-29 |
Angeletti P Ist Richerche Bio |
Procedimento per la produzione di peptidi con proprieta' inibitrici della proteasi ns3 del virus hcv, peptidi cosi' ottenibili e peptidi
|
AU3376699A
(en)
|
1998-03-31 |
1999-10-18 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hepatitis c virus ns3 protease
|
GB9812523D0
(en)
|
1998-06-10 |
1998-08-05 |
Angeletti P Ist Richerche Bio |
Peptide inhibitors of hepatitis c virus ns3 protease
|
AR022061A1
(es)
|
1998-08-10 |
2002-09-04 |
Boehringer Ingelheim Ca Ltd |
Peptidos inhibidores de la hepatitis c, una composicion farmaceutica que los contiene, el uso de los mismos para preparar una composicion farmaceutica, el uso de un producto intermedio para la preparacion de estos peptidos y un procedimiento para la preparacion de un peptido analogo de los mismos.
|
US6323180B1
(en)
*
|
1998-08-10 |
2001-11-27 |
Boehringer Ingelheim (Canada) Ltd |
Hepatitis C inhibitor tri-peptides
|
US6277830B1
(en)
|
1998-10-16 |
2001-08-21 |
Schering Corporation |
5′-amino acid esters of ribavirin and the use of same to treat hepatitis C with interferon
|
US7157430B2
(en)
*
|
1998-10-22 |
2007-01-02 |
Idun Pharmaceuticals, Inc. |
(Substituted)acyl dipeptidyl inhibitors of the ICE/CED-3 family of cysteine proteases
|
US6245740B1
(en)
|
1998-12-23 |
2001-06-12 |
Amgen Inc. |
Polyol:oil suspensions for the sustained release of proteins
|
US6608027B1
(en)
|
1999-04-06 |
2003-08-19 |
Boehringer Ingelheim (Canada) Ltd |
Macrocyclic peptides active against the hepatitis C virus
|
UA74546C2
(en)
|
1999-04-06 |
2006-01-16 |
Boehringer Ingelheim Ca Ltd |
Macrocyclic peptides having activity relative to hepatitis c virus, a pharmaceutical composition and use of the pharmaceutical composition
|
CA2365262C
(en)
|
1999-05-04 |
2008-06-10 |
Boehringer Ingelheim (Canada) Ltd. |
Surrogate cell-based system and method for assaying the activity of hepatitis c virus ns3 protease
|
US7256005B2
(en)
|
1999-08-10 |
2007-08-14 |
The Chancellor, Masters And Scholars Of The University Of Oxford |
Methods for identifying iminosugar derivatives that inhibit HCV p7 ion channel activity
|
ATE297946T1
(de)
|
2000-04-03 |
2005-07-15 |
Vertex Pharma |
Inhibitoren von serin proteasen, speziell der hepatitis-c-virus ns3-protease
|
IL151934A0
(en)
|
2000-04-05 |
2003-04-10 |
Schering Corp |
Macrocyclic ns3-serine protease inhibitors of hepatitis c virus comprising n-cyclic p2 moieties
|
NZ521456A
(en)
|
2000-04-19 |
2004-07-30 |
Schering Corp |
Macrocyclic NS3-Serine protease inhibitors of hepatitis C virus comprising alkyl and aryl alanine P2 moieties
|
DK1385870T3
(da)
*
|
2000-07-21 |
2010-07-05 |
Schering Corp |
Peptider som inhibitorer af NS3-serinprotease fra hepatitis C-virus
|
US7244721B2
(en)
|
2000-07-21 |
2007-07-17 |
Schering Corporation |
Peptides as NS3-serine protease inhibitors of hepatitis C virus
|
DE60119968T2
(de)
|
2000-11-20 |
2007-01-18 |
Bristol-Myers Squibb Co. |
Hepatitis c tripeptid inhibitoren
|
CA2446380A1
(en)
|
2001-05-08 |
2002-11-14 |
Yale University |
Proteomimetic compounds and methods
|
KR100926244B1
(ko)
|
2001-07-11 |
2009-11-12 |
버텍스 파마슈티칼스 인코포레이티드 |
브릿지된 바이사이클릭 세린 프로테아제 억제제
|
US6867185B2
(en)
|
2001-12-20 |
2005-03-15 |
Bristol-Myers Squibb Company |
Inhibitors of hepatitis C virus
|
US7119072B2
(en)
|
2002-01-30 |
2006-10-10 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis C virus
|
CA2369711A1
(en)
|
2002-01-30 |
2003-07-30 |
Boehringer Ingelheim (Canada) Ltd. |
Macrocyclic peptides active against the hepatitis c virus
|
CA2369970A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
CA2370396A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
US6642204B2
(en)
|
2002-02-01 |
2003-11-04 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
CA2370400A1
(en)
|
2002-02-01 |
2003-08-01 |
Boehringer Ingelheim (Canada) Ltd. |
Hepatitis c inhibitor tri-peptides
|
US7091184B2
(en)
|
2002-02-01 |
2006-08-15 |
Boehringer Ingelheim International Gmbh |
Hepatitis C inhibitor tri-peptides
|
US6828301B2
(en)
|
2002-02-07 |
2004-12-07 |
Boehringer Ingelheim International Gmbh |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
EP2468744A2
(de)
*
|
2002-04-11 |
2012-06-27 |
Vertex Pharmaceuticals Incorporated |
Inhibitoren der Serinproteasen, insbesondere der HCV-NS3-NS4A-Protease
|
MXPA04010527A
(es)
*
|
2002-04-26 |
2004-12-13 |
Gilead Sciences Inc |
Acumulacion celular de analogos de fosfonato de los compuestos inhibidores de la proteasa del virus de inmunodeficiencia humana (vih).
|
US6878722B2
(en)
|
2002-05-20 |
2005-04-12 |
Bristol-Myers Squibb Company |
Substituted cycloalkyl P1′ hepatitis C virus inhibitors
|
US20060199773A1
(en)
*
|
2002-05-20 |
2006-09-07 |
Sausker Justin B |
Crystalline forms of (1R,2S)-N-[(1,1-dimethylethoxy)carbonyl]-3-methyl-L-valyl-(4R)-4-[(6-methoxy-1-isoquinolinyl)oxy]-L-prolyl-1-amino-N-(cyclopropylsulfonyl)-2-ethenyl-cyclopropanecarboxamide, monopotassium salt
|
MY140680A
(en)
|
2002-05-20 |
2010-01-15 |
Bristol Myers Squibb Co |
Hepatitis c virus inhibitors
|
AU2003248535A1
(en)
|
2002-05-20 |
2003-12-12 |
Bristol-Myers Squibb Company |
Heterocyclicsulfonamide hepatitis c virus inhibitors
|
AU2003299519A1
(en)
|
2002-05-20 |
2004-05-04 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
US20040033959A1
(en)
|
2002-07-19 |
2004-02-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
US20040138109A1
(en)
|
2002-09-30 |
2004-07-15 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Potent inhibitor of HCV serine protease
|
PL199412B1
(pl)
|
2002-10-15 |
2008-09-30 |
Boehringer Ingelheim Int |
Nowe kompleksy rutenu jako (pre)katalizatory reakcji metatezy, pochodne 2-alkoksy-5-nitrostyrenu jako związki pośrednie i sposób ich wytwarzania
|
US20050075279A1
(en)
|
2002-10-25 |
2005-04-07 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
US7601709B2
(en)
*
|
2003-02-07 |
2009-10-13 |
Enanta Pharmaceuticals, Inc. |
Macrocyclic hepatitis C serine protease inhibitors
|
US20040180815A1
(en)
|
2003-03-07 |
2004-09-16 |
Suanne Nakajima |
Pyridazinonyl macrocyclic hepatitis C serine protease inhibitors
|
JP2007524576A
(ja)
|
2003-02-07 |
2007-08-30 |
エナンタ ファーマシューティカルズ インコーポレイテッド |
大環状のc型肝炎セリンプロテアーゼ阻害剤
|
JP4550824B2
(ja)
|
2003-03-05 |
2010-09-22 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
C型肝炎抑制化合物
|
UY28240A1
(es)
|
2003-03-27 |
2004-11-08 |
Boehringer Ingelheim Pharma |
Fases cristalinas de un potente inhibidor de la hcv
|
UA81028C2
(en)
|
2003-04-02 |
2007-11-26 |
Boehringer Ingelheim Int |
Pharmaceutical compositions for hepatitis c viral protease inhibitors
|
US7148347B2
(en)
|
2003-04-10 |
2006-12-12 |
Boehringer Ingelheim International Gmbh |
Process for preparing macrocyclic compounds
|
WO2004089974A1
(en)
|
2003-04-10 |
2004-10-21 |
Boehringer Ingelheim International Gmbh |
Process for the preparation of macrocyclic compounds by ruthenium complex catalysed metathesis reaction
|
EP1613620A1
(de)
*
|
2003-04-11 |
2006-01-11 |
Vertex Pharmaceuticals Incorporated |
Inhibitoren von serinproteasen, insbesondere hcv-ns3-ns4a-protease
|
ES2386161T3
(es)
|
2003-04-16 |
2012-08-10 |
Bristol-Myers Squibb Company |
Proceso para separar una mezcla de enantiómeros de éster alquílico usando una enzima
|
US7176208B2
(en)
|
2003-04-18 |
2007-02-13 |
Enanta Pharmaceuticals, Inc. |
Quinoxalinyl macrocyclic hepatitis C serine protease inhibitors
|
EP1628685B1
(de)
*
|
2003-04-25 |
2010-12-08 |
Gilead Sciences, Inc. |
Antivirale phosphonate analoge
|
WO2004096285A2
(en)
*
|
2003-04-25 |
2004-11-11 |
Gilead Sciences, Inc. |
Anti-infective phosphonate conjugates
|
WO2004099134A2
(en)
|
2003-05-05 |
2004-11-18 |
Prosidion Ltd. |
Glutaminyl based dp iv-inhibitors
|
US7273851B2
(en)
|
2003-06-05 |
2007-09-25 |
Enanta Pharmaceuticals, Inc. |
Tri-peptide hepatitis C serine protease inhibitors
|
US7125845B2
(en)
|
2003-07-03 |
2006-10-24 |
Enanta Pharmaceuticals, Inc. |
Aza-peptide macrocyclic hepatitis C serine protease inhibitors
|
TWI359147B
(en)
|
2003-09-05 |
2012-03-01 |
Vertex Pharma |
Inhibitors of serine proteases, particularly hcv n
|
AU2004274468B2
(en)
|
2003-09-18 |
2009-07-23 |
Vertex Pharmaceuticals, Incorporated |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
|
AU2004274051A1
(en)
|
2003-09-22 |
2005-03-31 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis C virus
|
MXPA06003455A
(es)
*
|
2003-09-26 |
2006-05-31 |
Schering Corp |
Inhibidores macrociclicos de la serina proteasa ns3 del virus de la hepatitis c.
|
AU2004282148A1
(en)
|
2003-10-10 |
2005-04-28 |
Vertex Pharmaceuticals Incoporated |
Inhibitors of serine proteases, particularly HCV NS3-NS4A protease
|
US7491794B2
(en)
*
|
2003-10-14 |
2009-02-17 |
Intermune, Inc. |
Macrocyclic compounds as inhibitors of viral replication
|
CN102020697B
(zh)
|
2003-10-14 |
2014-10-29 |
F·霍夫曼-罗须公司 |
作为hcv复制抑制剂的巨环羧酸和酰基磺酰胺
|
AU2004285019B9
(en)
|
2003-10-27 |
2011-11-24 |
Vertex Pharmaceuticals Incorporated |
HCV NS3-NS4A protease resistance mutants
|
US7132504B2
(en)
|
2003-11-12 |
2006-11-07 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7135462B2
(en)
|
2003-11-20 |
2006-11-14 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
CA2539575C
(en)
|
2003-11-20 |
2015-01-20 |
Boehringer Ingelheim International Gmbh |
Method of removing transition metals, especially from metathesis reaction products
|
US7309708B2
(en)
|
2003-11-20 |
2007-12-18 |
Birstol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
ATE424926T1
(de)
|
2003-12-08 |
2009-03-15 |
Boehringer Ingelheim Int |
Abtrennung von ruthenium-nebenprodukten durch behandlung mit überkritischen flüssigkeiten
|
CN100509784C
(zh)
*
|
2003-12-11 |
2009-07-08 |
先灵公司 |
丙型肝炎病毒ns3/ns4a丝氨酸蛋白酶的抑制剂
|
CA2549851C
(en)
|
2004-01-21 |
2012-09-11 |
Boehringer Ingelheim International Gmbh |
Macrocyclic peptides active against the hepatitis c virus
|
JP4769200B2
(ja)
|
2004-01-28 |
2011-09-07 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
遷移金属副生成物を含む反応溶液から遷移金属を除去する方法
|
DK1713823T3
(da)
|
2004-01-30 |
2010-03-08 |
Medivir Ab |
HCV NS-3 serinproteaseinhibitorer
|
CA2554999A1
(en)
|
2004-02-04 |
2005-08-25 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of serine proteases, particularly hcv ns3-ns4a protease
|
ES2327544T3
(es)
|
2004-02-27 |
2009-10-30 |
Schering Corporation |
Compuestos novedosos como inhibidores de serina proteasa ns3 de virus de hepetitis c.
|
US7173057B2
(en)
|
2004-02-27 |
2007-02-06 |
Schering Corporation |
Ketoamides with cyclic P4'S as inhibitors of NS3 protease of hepatitis C virus
|
EP1737821B1
(de)
*
|
2004-02-27 |
2009-08-05 |
Schering Corporation |
3,4-(cyclopentyl)kondensierte prolinverbindungen als inhibitoren der ns3-serinprotease des hepatitis-c-virus
|
KR20060124725A
(ko)
|
2004-02-27 |
2006-12-05 |
쉐링 코포레이션 |
C형 간염 바이러스 ns3 프로테아제의 억제제
|
US7816326B2
(en)
*
|
2004-02-27 |
2010-10-19 |
Schering Corporation |
Sulfur compounds as inhibitors of hepatitis C virus NS3 serine protease
|
ATE459638T1
(de)
|
2004-03-15 |
2010-03-15 |
Boehringer Ingelheim Int |
Verfahren zur herstellung makrocyclischer dipeptide, die sich für die behandlung von hepatitis-c-virusinfektionen eignen
|
WO2005097820A1
(en)
|
2004-04-06 |
2005-10-20 |
Korea Research Institute Of Bioscience And Biotechnology |
Peptides for inhibiting mdm2 function
|
EP1773868B1
(de)
|
2004-05-20 |
2009-07-15 |
Schering Corporation |
Substituierte proline als hemmer der ns3-serinprotease des hepatits-c-virus
|
JP5156374B2
(ja)
|
2004-05-25 |
2013-03-06 |
ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング |
非環式hcvプロテアーゼインヒビターの調製方法
|
US7939538B2
(en)
*
|
2004-06-28 |
2011-05-10 |
Amgen Inc. |
Compounds, compositions and methods for prevention and treatment of inflammatory and immunoregulatory disorders and diseases
|
DE102004033312A1
(de)
*
|
2004-07-08 |
2006-01-26 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Kontinuierliches Metatheseverfahren mit Ruthenium-Katalysatoren
|
JP5676839B2
(ja)
|
2004-07-16 |
2015-02-25 |
ギリアード サイエンシーズ, インコーポレイテッド |
抗ウイルス化合物
|
UY29016A1
(es)
|
2004-07-20 |
2006-02-24 |
Boehringer Ingelheim Int |
Analogos de dipeptidos inhibidores de la hepatitis c
|
CA2573346C
(en)
|
2004-07-20 |
2011-09-20 |
Boehringer Ingelheim International Gmbh |
Hepatitis c inhibitor peptide analogs
|
CA2577812A1
(en)
|
2004-08-27 |
2006-03-09 |
Schering Corporation |
Acylsulfonamide compounds as inhibitors of hepatitis c virus ns3 serine protease
|
WO2006033878A1
(en)
|
2004-09-17 |
2006-03-30 |
Boehringer Ingelheim International, Gmbh |
Process for preparing macrocyclic hcv protease inhibitors
|
US7189844B2
(en)
|
2004-09-17 |
2007-03-13 |
Boehringer Ingelheim International Gmbh |
Ring-closing metathesis process in supercritical fluid
|
WO2006045096A2
(en)
|
2004-10-20 |
2006-04-27 |
Resverlogix Corp. |
Flavanoids and isoflavanoids for the prevention and treatment of cardiovascular diseases
|
DE102005002336A1
(de)
|
2005-01-17 |
2006-07-20 |
Boehringer Ingelheim Pharma Gmbh & Co. Kg |
Verfahren zur Durchführung von kontinuierlichen Olefin-Ringschluss-Metathesen in komprimiertem Kohlendioxid
|
US7323447B2
(en)
|
2005-02-08 |
2008-01-29 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7524831B2
(en)
*
|
2005-03-02 |
2009-04-28 |
Schering Corporation |
Treatments for Flaviviridae virus infection
|
CA2603711C
(en)
|
2005-03-04 |
2013-06-18 |
The Rockefeller University |
Infectious, chimeric hepatitis c virus, methods of producing the same and methods of use thereof
|
WO2006096652A2
(en)
|
2005-03-08 |
2006-09-14 |
Boehringer Ingelheim International Gmbh |
Process for preparing macrocyclic compounds
|
WO2006113942A2
(en)
|
2005-04-20 |
2006-10-26 |
Schering Corporation |
Method of inhibiting cathepsin activity
|
WO2006119061A2
(en)
|
2005-05-02 |
2006-11-09 |
Merck & Co., Inc. |
Hcv ns3 protease inhibitors
|
US20060269516A1
(en)
*
|
2005-05-26 |
2006-11-30 |
Schering Corporation |
Interferon-IgG fusion
|
US20060276407A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods of treating hepatitis C virus
|
US20060281689A1
(en)
|
2005-06-02 |
2006-12-14 |
Schering Corporation |
Method for modulating activity of HCV protease through use of a novel HCV protease inhibitor to reduce duration of treatment period
|
WO2006130553A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Hcv protease inhibitors
|
US20070021351A1
(en)
|
2005-06-02 |
2007-01-25 |
Schering Corporation |
Liver/plasma concentration ratio for dosing hepatitis C virus protease inhibitor
|
WO2006130627A2
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Methods for treating hepatitis c
|
NZ563365A
(en)
|
2005-06-02 |
2011-02-25 |
Schering Corp |
Combination of HCV protease inhibitors with a surfactant
|
US20060287248A1
(en)
|
2005-06-02 |
2006-12-21 |
Schering Corporation |
Asymmetric dosing methods
|
AU2006252519B2
(en)
|
2005-06-02 |
2012-08-30 |
Merck Sharp & Dohme Corp. |
HCV protease inhibitors in combination with food
|
US20060276404A1
(en)
|
2005-06-02 |
2006-12-07 |
Anima Ghosal |
Medicaments and methods combining a HCV protease inhibitor and an AKR competitor
|
US20060275366A1
(en)
|
2005-06-02 |
2006-12-07 |
Schering Corporation |
Controlled-release formulation
|
US7608592B2
(en)
*
|
2005-06-30 |
2009-10-27 |
Virobay, Inc. |
HCV inhibitors
|
US7601686B2
(en)
|
2005-07-11 |
2009-10-13 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
TWI389908B
(zh)
|
2005-07-14 |
2013-03-21 |
Gilead Sciences Inc |
抗病毒化合物類
|
TWI387603B
(zh)
|
2005-07-20 |
2013-03-01 |
Merck Sharp & Dohme |
Hcv ns3蛋白酶抑制劑
|
KR101294467B1
(ko)
|
2005-07-25 |
2013-09-09 |
인터뮨, 인크. |
C형 간염 바이러스 복제의 신규 거대고리형 억제제
|
BRPI0613933A2
(pt)
|
2005-07-29 |
2011-02-22 |
Medivir Ab |
inibidores macrocìlicos do vìrus da hepatite c
|
CN101273027B
(zh)
|
2005-07-29 |
2015-12-02 |
爱尔兰詹森科学公司 |
丙型肝炎病毒的大环抑制剂
|
PE20070343A1
(es)
|
2005-07-29 |
2007-05-12 |
Medivir Ab |
Inhibidores macrociclicos del virus de la hepatitis c
|
US20090325889A1
(en)
|
2005-08-01 |
2009-12-31 |
David Alan Campbell |
Hepatitis c serine protease inhibitors and uses therefor
|
AU2006301966A1
(en)
|
2005-10-11 |
2007-04-19 |
Array Biopharma, Inc. |
Compounds and methods for inhibiting hepatitis C viral replication
|
US7772183B2
(en)
|
2005-10-12 |
2010-08-10 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7741281B2
(en)
|
2005-11-03 |
2010-06-22 |
Bristol-Myers Squibb Company |
Hepatitis C virus inhibitors
|
US7705138B2
(en)
*
|
2005-11-11 |
2010-04-27 |
Vertex Pharmaceuticals Incorporated |
Hepatitis C virus variants
|
JP2009515925A
(ja)
*
|
2005-11-16 |
2009-04-16 |
エフ.ホフマン−ラ ロシュ アーゲー |
凝固第Xa因子のインヒビターとしての新規なピロリジン誘導体
|
JP2009526070A
(ja)
|
2006-02-09 |
2009-07-16 |
シェーリング コーポレイション |
Hcvプロテアーゼ阻害薬とhcvポリメラーゼ阻害薬との組み合わせ、ならびにそれらに関連する処置の方法
|
KR20080112303A
(ko)
*
|
2006-03-16 |
2008-12-24 |
버텍스 파마슈티칼스 인코포레이티드 |
중수소화 c형 간염 프로테아제 억제제
|
CA2647158C
(en)
|
2006-03-23 |
2012-07-31 |
Schering Corporation |
Combinations of hcv protease inhibitor(s) and cyp3a4 inhibitor(s), and methods of treatment related thereto
|
BRPI0710878A2
(pt)
|
2006-04-11 |
2015-03-31 |
Novartis Ag |
Compostos orgânicos e seus usos
|
US20080187516A1
(en)
|
2006-06-06 |
2008-08-07 |
Ying Sun |
Acyclic oximyl hepatitis c protease inhibitors
|
US9526769B2
(en)
|
2006-06-06 |
2016-12-27 |
Enanta Pharmaceuticals, Inc. |
Macrocylic oximyl hepatitis C protease inhibitors
|
US7728148B2
(en)
|
2006-06-06 |
2010-06-01 |
Enanta Pharmaceuticals, Inc. |
Acyclic oximyl hepatitis C protease inhibitors
|
EP2029741A4
(de)
*
|
2006-06-08 |
2011-03-16 |
Merck Sharp & Dohme |
Schnellverfahren zur bestimmung der hemmersensitivität von aus klinischen proben geklonten ns3/4a-proteasesequenzen
|
UY30437A1
(es)
|
2006-06-26 |
2008-01-31 |
Enanta Pharm Inc |
Quinoxalinil macroceclicos inhibidores de serina proteasa del virus de la hepatitis c
|
RU2008152171A
(ru)
|
2006-07-05 |
2010-08-10 |
Интермьюн, Инк. (Us) |
Новые ингибиторы вирусной репликации гепатита с
|
WO2008008776A2
(en)
*
|
2006-07-11 |
2008-01-17 |
Bristol-Myers Squibb Company |
Hepatitis c virus inhibitors
|
EA017448B1
(ru)
|
2006-07-13 |
2012-12-28 |
Ачиллион Фармасьютикалз, Инк. |
4-амино-4-оксобутаноиловые пептиды как ингибиторы вирусной репликации
|
US20090035267A1
(en)
|
2007-07-31 |
2009-02-05 |
Moore Joel D |
Acyclic, pyridazinone-derived hepatitis c serine protease inhibitors
|
US7635683B2
(en)
*
|
2006-08-04 |
2009-12-22 |
Enanta Pharmaceuticals, Inc. |
Quinoxalinyl tripeptide hepatitis C virus inhibitors
|
WO2008019289A2
(en)
|
2006-08-04 |
2008-02-14 |
Enanta Pharmaceuticals, Inc. |
Tetrazolyl macrocyclic hepatitis c serine protease inhibitors
|
WO2008019303A2
(en)
|
2006-08-04 |
2008-02-14 |
Enanta Pharmaceuticals, Inc. |
Pyridazinonyl macrocyclic hepatitis c serine protease inhibitors
|
WO2008021960A2
(en)
|
2006-08-11 |
2008-02-21 |
Enanta Pharmaceuticals, Inc. |
Triazolyl macrocyclic hepatitis c serine protease inhibitors
|
WO2008022006A2
(en)
|
2006-08-11 |
2008-02-21 |
Enanta Pharmaceuticals, Inc. |
Arylalkoxyl hepatitis c virus protease inhibitors
|
US20090098085A1
(en)
*
|
2006-08-11 |
2009-04-16 |
Ying Sun |
Tetrazolyl acyclic hepatitis c serine protease inhibitors
|
US7605126B2
(en)
*
|
2006-08-11 |
2009-10-20 |
Enanta Pharmaceuticals, Inc. |
Acylaminoheteroaryl hepatitis C virus protease inhibitors
|
US20080038225A1
(en)
|
2006-08-11 |
2008-02-14 |
Ying Sun |
Triazolyl acyclic hepatitis c serine protease inhibitors
|
US7687459B2
(en)
*
|
2006-08-11 |
2010-03-30 |
Enanta Pharmaceuticals, Inc. |
Arylalkoxyl hepatitis C virus protease inhibitors
|
CA2686138A1
(en)
*
|
2007-05-03 |
2008-11-13 |
Intermune, Inc. |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
AP2009005057A0
(en)
*
|
2007-05-10 |
2009-12-31 |
Array Biopharma Inc |
Novel peptide inhibitors of hepatitis c virus replication
|
WO2009142842A2
(en)
*
|
2008-04-15 |
2009-11-26 |
Intermune, Inc. |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
EP2358736A1
(de)
*
|
2008-10-15 |
2011-08-24 |
Intermune, Inc. |
Therapeutische antivirale peptide
|
US9388405B2
(en)
|
2009-02-18 |
2016-07-12 |
Wayne State University |
Method for identifying a subpopulation of mammalian cells with distinctive ribosome translation profiles
|
AR075584A1
(es)
*
|
2009-02-27 |
2011-04-20 |
Intermune Inc |
COMPOSICIONES TERAPEUTICAS QUE COMPRENDEN beta-D-2'-DESOXI-2'-FLUORO-2'-C-METILCITIDINA Y UN DERIVADO DE ACIDO ISOINDOL CARBOXILICO Y SUS USOS. COMPUESTO.
|
CN102741270B
(zh)
*
|
2009-09-28 |
2015-07-22 |
英特穆恩公司 |
C型肝炎病毒复制的环肽抑制剂
|
US20110129444A1
(en)
*
|
2009-09-28 |
2011-06-02 |
Intermune, Inc |
Novel macrocyclic inhibitors of hepatitis c virus replication
|
US20110082182A1
(en)
*
|
2009-10-01 |
2011-04-07 |
Intermune, Inc. |
Therapeutic antiviral peptides
|