NO20072142L - Mellomprodukter for fremstilling av heterocyklylalkylpiperidinderivater og forbindelser for fremstilling av disse - Google Patents

Mellomprodukter for fremstilling av heterocyklylalkylpiperidinderivater og forbindelser for fremstilling av disse

Info

Publication number
NO20072142L
NO20072142L NO20072142A NO20072142A NO20072142L NO 20072142 L NO20072142 L NO 20072142L NO 20072142 A NO20072142 A NO 20072142A NO 20072142 A NO20072142 A NO 20072142A NO 20072142 L NO20072142 L NO 20072142L
Authority
NO
Norway
Prior art keywords
preparation
intermediates
compounds
methoxyquinoline
chloro
Prior art date
Application number
NO20072142A
Other languages
English (en)
Inventor
Jean-Luc Malleron
Serge Mignani
Michel Evers
Guy Pantel
Michel Tabart
Fabrice Viviani
Eric Bacque
Jean-Christophe Carry
Youssef El-Ahmad
Philippe Hubert
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Publication of NO20072142L publication Critical patent/NO20072142L/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/20—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

Det beskrives en hvilken som helst fiorbindelse valgt blant 4-klor-3 -fluor-6-metoksykinolin, 4-brom-3 -fluor-6-metoksykinolin, 4-j od-3 -fluor-6-metoksykinolin, 4-brom-3 -klor-6-metoksykinolin, 4-j od-3 -klor-6-metoksykinolin, 4-hydroksy-3 -klor-6-metoksykinolin og 3-fluor-6-metoksykinolin.
NO20072142A 2000-11-15 2007-04-25 Mellomprodukter for fremstilling av heterocyklylalkylpiperidinderivater og forbindelser for fremstilling av disse NO20072142L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR0014738A FR2816618B1 (fr) 2000-11-15 2000-11-15 Derives heterocyclylalcoyl piperidine, leur preparation et les compositions qui les contiennent
PCT/FR2001/003559 WO2002040474A2 (fr) 2000-11-15 2001-11-14 Derives heterocyclylalcoyl piperidine et leur application comme antimicrobiens

Publications (1)

Publication Number Publication Date
NO20072142L true NO20072142L (no) 2007-04-25

Family

ID=8856503

Family Applications (2)

Application Number Title Priority Date Filing Date
NO20032187A NO20032187L (no) 2000-11-15 2003-05-14 Heterocyklylalkylpiperidinderivater, deres fremstilling samt preparater inneholdende forbindelsene
NO20072142A NO20072142L (no) 2000-11-15 2007-04-25 Mellomprodukter for fremstilling av heterocyklylalkylpiperidinderivater og forbindelser for fremstilling av disse

Family Applications Before (1)

Application Number Title Priority Date Filing Date
NO20032187A NO20032187L (no) 2000-11-15 2003-05-14 Heterocyklylalkylpiperidinderivater, deres fremstilling samt preparater inneholdende forbindelsene

Country Status (28)

Country Link
EP (2) EP1695964A1 (no)
JP (1) JP2004514661A (no)
KR (1) KR100849608B1 (no)
CN (1) CN1483031A (no)
AR (1) AR034006A1 (no)
AT (1) ATE337311T1 (no)
AU (2) AU1836502A (no)
BG (1) BG107793A (no)
BR (1) BR0115312A (no)
CA (1) CA2429311A1 (no)
CZ (1) CZ20031316A3 (no)
DE (1) DE60122567T2 (no)
DK (1) DK1337529T3 (no)
EA (1) EA200300568A1 (no)
EE (1) EE200300207A (no)
ES (1) ES2271119T3 (no)
FR (1) FR2816618B1 (no)
HR (1) HRP20030379A2 (no)
HU (1) HUP0303758A3 (no)
IL (1) IL155841A0 (no)
NO (2) NO20032187L (no)
PL (1) PL363004A1 (no)
PT (1) PT1337529E (no)
SK (1) SK5822003A3 (no)
TN (1) TNSN01160A1 (no)
WO (1) WO2002040474A2 (no)
YU (1) YU46803A (no)
ZA (1) ZA200303794B (no)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
PL366335A1 (en) 2000-07-26 2005-01-24 Smithkline Beecham P.L.C. Aminopiperidine quinolines and their azaisosteric analogues with antibacterial activity
GB0101577D0 (en) 2001-01-22 2001-03-07 Smithkline Beecham Plc Compounds
GB0112836D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0112834D0 (en) 2001-05-25 2001-07-18 Smithkline Beecham Plc Medicaments
GB0118238D0 (en) * 2001-07-26 2001-09-19 Smithkline Beecham Plc Medicaments
AU2003239302A1 (en) 2002-01-29 2003-09-02 Glaxo Group Limited Aminopiperidine compounds, process for their preparation, and pharmaceutical compositions containing them
TW200406410A (en) 2002-01-29 2004-05-01 Glaxo Group Ltd Compounds
TW200406413A (en) 2002-06-26 2004-05-01 Glaxo Group Ltd Compounds
AR040336A1 (es) 2002-06-26 2005-03-30 Glaxo Group Ltd Compuesto de piperidina, uso del mismo para la fabricacion de un medicamento, composicion farmaceutica que lo comprende y procedimiento para preparar dicho compuesto
FR2842807A1 (fr) * 2002-07-23 2004-01-30 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, procede et intermediaires de preparation et compositions les renfermant
GB0217294D0 (en) * 2002-07-25 2002-09-04 Glaxo Group Ltd Medicaments
FR2844268B1 (fr) 2002-09-11 2004-10-22 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leurs procedes et intermediaires de preparation et les compositions qui les contiennent
FR2844270B1 (fr) 2002-09-11 2006-05-19 Aventis Pharma Sa Derives de la quinolyl propyl piperidine, leur procede et intermediaires de preparation et les compositions qui les contiennent
DE10256405A1 (de) * 2002-12-02 2004-06-17 Morphochem Aktiengesellschaft für kombinatorische Chemie Neue Verbindungen, die Topoisomerase IV inhibieren
DE60331849D1 (de) 2002-11-05 2010-05-06 Glaxosmithkline Llc Antibakterielle wirkstoffe
EP1567520B1 (en) 2002-12-04 2008-10-15 Glaxo Group Limited Quinolines and nitrogenated derivatives thereof and their use as antibacterial agents
US7232833B2 (en) 2003-03-28 2007-06-19 Novexel 4-substituted quinoline derivatives, method and intermediates for their preparation and pharmaceutical compositions containing them
FR2852954B1 (fr) * 2003-03-28 2006-07-14 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
FR2862301B1 (fr) * 2003-11-17 2007-12-21 Aventis Pharma Sa Nouveau procede de preparation de quinoleines 3-fluorees
FR2867472B1 (fr) * 2004-03-12 2008-07-18 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent
US7592334B2 (en) 2005-01-25 2009-09-22 Glaxo Group Limited Antibacterial agents
US7605169B2 (en) 2005-01-25 2009-10-20 Glaxo Group Limited Antibacterial agents
EP1845995A4 (en) 2005-01-25 2010-03-03 Glaxo Group Ltd ANTIBACTERIAL AGENTS
JP2008528586A (ja) 2005-01-25 2008-07-31 グラクソ グループ リミテッド 抗菌剤
MX2007010572A (es) 2005-03-01 2007-10-04 Wyeth Corp Compuestos de cinolina y su uso como moduladores de receptor x de higado.
MY150958A (en) * 2005-06-16 2014-03-31 Astrazeneca Ab Compounds for the treatment of multi-drug resistant bacterial infections
JP2009524643A (ja) 2006-01-26 2009-07-02 アクテリオン ファーマシューティカルズ リミテッド テトラヒドロピラン抗生物質
JP2009532423A (ja) 2006-04-06 2009-09-10 グラクソ グループ リミテッド 抗菌剤としてのピロロ−キノキサリノン誘導体
EP1992628A1 (en) 2007-05-18 2008-11-19 Glaxo Group Limited Derivatives and analogs of N-ethylquinolones and N-ethylazaquinolones
EP2167494B1 (en) 2007-06-15 2011-08-17 Actelion Pharmaceuticals Ltd. 3-amino-6-(1-amino-ethyl)-tetrahydropyran derivatives
EP2080761A1 (en) 2008-01-18 2009-07-22 Glaxo Group Limited Compounds
WO2010043714A1 (en) 2008-10-17 2010-04-22 Glaxo Group Limited Tricyclic nitrogen compounds used as antibacterials
ES2561631T3 (es) 2009-01-15 2016-02-29 Glaxo Group Limited Compuestos de naftiridin-2(1H)-ona útiles como agentes antibacterianos
WO2014027045A1 (en) * 2012-08-15 2014-02-20 Glaxo Group Limited Chemical process
EP3182973B1 (en) 2014-08-22 2019-09-18 GlaxoSmithKline Intellectual Property Development Limited Tricyclic nitrogen containing compounds for treating neisseria gonorrhoea infection
WO2016138988A1 (en) * 2015-03-02 2016-09-09 University Of Copenhagen Piperazine inhibitors of bacterial gyrase and topoisomerase iv
TW201722965A (zh) 2015-08-16 2017-07-01 葛蘭素史密斯克藍智慧財產發展有限公司 用於抗菌應用之化合物

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL7908031A (nl) 1979-11-01 1981-06-01 Acf Chemiefarma Nv Nieuwe chinolinederivaten en farmaceutische preparaten die een dergelijke verbinding bevatten, alsmede werk- wijze voor het bereiden van deze verbindingen.
JPH0239546A (ja) 1988-07-29 1990-02-08 Origin Electric Co Ltd 混成集積回路の製造方法
AU623474B2 (en) 1989-01-16 1992-05-14 Laboratoire Roger Bellon New benzo(1,8)naphthyridine derivatives, their preparation and compositions containing them
AU2717899A (en) * 1998-01-26 1999-08-09 Smithkline Beecham Plc Quinoline derivatives as antibacterials
WO2000043383A1 (en) * 1999-01-20 2000-07-27 Smithkline Beecham P.L.C. Piperidinylquinolines as protein tyrosine kinase inhibitors
FR2852954B1 (fr) * 2003-03-28 2006-07-14 Aventis Pharma Sa Derives de quinoleines-4-substituees, leurs procede et intermediaires de preparation et les compositions pharmaceutiques qui les contiennent

Also Published As

Publication number Publication date
HRP20030379A2 (en) 2005-04-30
FR2816618A1 (fr) 2002-05-17
DK1337529T3 (da) 2006-12-18
SK5822003A3 (en) 2004-06-08
EP1695964A1 (fr) 2006-08-30
BG107793A (bg) 2004-08-31
CZ20031316A3 (cs) 2003-10-15
AU2002218365B2 (en) 2007-07-05
KR20030060934A (ko) 2003-07-16
EE200300207A (et) 2003-08-15
ATE337311T1 (de) 2006-09-15
AR034006A1 (es) 2004-01-21
KR100849608B1 (ko) 2008-07-31
PL363004A1 (en) 2004-11-15
WO2002040474A2 (fr) 2002-05-23
TNSN01160A1 (fr) 2005-11-10
PT1337529E (pt) 2006-12-29
ZA200303794B (en) 2004-06-29
YU46803A (sh) 2006-05-25
WO2002040474A3 (fr) 2002-10-31
HUP0303758A2 (hu) 2004-03-01
ES2271119T3 (es) 2007-04-16
NO20032187L (no) 2003-06-26
CN1483031A (zh) 2004-03-17
DE60122567D1 (de) 2006-10-05
BR0115312A (pt) 2003-09-23
AU1836502A (en) 2002-05-27
FR2816618B1 (fr) 2002-12-27
EP1337529A2 (fr) 2003-08-27
EA200300568A1 (ru) 2003-12-25
CA2429311A1 (en) 2002-05-23
EP1337529B1 (fr) 2006-08-23
IL155841A0 (en) 2003-12-23
NO20032187D0 (no) 2003-05-14
DE60122567T2 (de) 2007-08-23
JP2004514661A (ja) 2004-05-20
HUP0303758A3 (en) 2009-08-28

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Legal Events

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