NO20062492L - Fremgangsmate for fremstilling av tubulininhibitorer - Google Patents

Fremgangsmate for fremstilling av tubulininhibitorer

Info

Publication number
NO20062492L
NO20062492L NO20062492A NO20062492A NO20062492L NO 20062492 L NO20062492 L NO 20062492L NO 20062492 A NO20062492 A NO 20062492A NO 20062492 A NO20062492 A NO 20062492A NO 20062492 L NO20062492 L NO 20062492L
Authority
NO
Norway
Prior art keywords
alkyl
preparation
atom
tubulin inhibitors
substituted
Prior art date
Application number
NO20062492A
Other languages
English (en)
Norwegian (no)
Inventor
Semiramis Ayral-Kaloustian
Yanzhong Wu
David Michael Blum
Jean Schmid
Jay Thomas Afragola
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Publication of NO20062492L publication Critical patent/NO20062492L/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
NO20062492A 2003-12-08 2006-05-31 Fremgangsmate for fremstilling av tubulininhibitorer NO20062492L (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US52793103P 2003-12-08 2003-12-08
PCT/US2004/040854 WO2005056560A1 (en) 2003-12-08 2004-12-07 Process for the preparation of tubulin inhibitors

Publications (1)

Publication Number Publication Date
NO20062492L true NO20062492L (no) 2006-07-03

Family

ID=34676796

Family Applications (1)

Application Number Title Priority Date Filing Date
NO20062492A NO20062492L (no) 2003-12-08 2006-05-31 Fremgangsmate for fremstilling av tubulininhibitorer

Country Status (29)

Country Link
US (1) US7396835B2 (es)
EP (1) EP1692137B1 (es)
JP (1) JP2007513185A (es)
KR (1) KR20060094984A (es)
CN (1) CN1890245A (es)
AR (1) AR046939A1 (es)
AT (1) ATE356128T1 (es)
AU (1) AU2004297244A1 (es)
BR (1) BRPI0417422A (es)
CA (1) CA2546899A1 (es)
CO (1) CO5700827A2 (es)
CR (1) CR8435A (es)
DE (1) DE602004005239T2 (es)
DK (1) DK1692137T3 (es)
EC (1) ECSP066606A (es)
ES (1) ES2281850T3 (es)
GT (1) GT200400248A (es)
HK (1) HK1090377A1 (es)
IL (1) IL175775A0 (es)
MY (1) MY179926A (es)
NO (1) NO20062492L (es)
NZ (1) NZ547471A (es)
PA (1) PA8619401A1 (es)
PE (1) PE20050593A1 (es)
PL (1) PL1692137T3 (es)
RU (1) RU2006117023A (es)
TW (1) TW200522963A (es)
WO (1) WO2005056560A1 (es)
ZA (1) ZA200604680B (es)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6255309B1 (en) * 1999-03-19 2001-07-03 American Cyanomid Co. Fungicidal trifluoromethylalkylamino-triazolopyrimidines
US7419982B2 (en) * 2003-09-24 2008-09-02 Wyeth Holdings Corporation Crystalline forms of 5-chloro-6-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-N-[(1S)-2,2,2-trifluoro-1-methylethyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine salts
TW200800959A (en) 2005-06-10 2008-01-01 Wyeth Corp Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor
TW200808730A (en) * 2006-06-09 2008-02-16 Wyeth Corp Process for synthesizing piperazine-piperidine compounds
US20100056371A1 (en) * 2007-01-08 2010-03-04 Basf Se Use of Azolopyrimidines for Controlling Phytopathogenic Harmful Fungi
US9649317B2 (en) 2012-09-19 2017-05-16 The Trustees Of The University Of Pennsylvania Heterocyclic compounds and their use for the treatment of neurodegenerative tauopathies
WO2019169111A1 (en) 2018-03-02 2019-09-06 The Trustees Of The University Of Pennsylvania [1,2,4]triazolo[1,5-a]pyrimidine compounds and use in stabilizing microtubules

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5593996A (en) 1991-12-30 1997-01-14 American Cyanamid Company Triazolopyrimidine derivatives
TW224044B (es) 1991-12-30 1994-05-21 Shell Internat Res Schappej B V
JP2794510B2 (ja) 1992-03-27 1998-09-10 富士写真フイルム株式会社 ハロゲン化銀写真感光材料
IL108747A (en) 1993-03-04 1999-03-12 Shell Int Research Mushroom-killing preparations containing a history of 6 metamorphoses of 5 - 7 Dihalo - 1, 2 - 4 Triazlo [A-1,5] Pyrimidine Certain such new compounds and their preparation
TW258648B (es) 1993-03-04 1995-10-01 Shell Internat Res Schappej Bv
RU2147584C1 (ru) 1995-10-27 2000-04-20 Американ Цианамид Компани Способ получения дигалоидазолопиримидинов и способ получения дигидроксиазолопиримидинов
US5817663A (en) 1996-10-07 1998-10-06 American Cyanamid Company Pentafluorophenylazolopyrimidines
US5750766A (en) 1997-03-18 1998-05-12 American Cyanamid Company Process for the preparation of arylmalonates
EP0984919B1 (en) 1997-03-18 2003-01-22 Basf Aktiengesellschaft Process for the preparation of arylmalonates
US5948783A (en) 1997-04-14 1999-09-07 American Cyanamid Company Fungicidal trifluoromethylalkylamino-triazolopyrimidines
TW460476B (en) 1997-04-14 2001-10-21 American Cyanamid Co Fungicidal trifluoromethylalkylamino-triazolopyrimidines
US6117876A (en) 1997-04-14 2000-09-12 American Cyanamid Company Fungicidal trifluorophenyl-triazolopyrimidines
TWI252231B (en) 1997-04-14 2006-04-01 American Cyanamid Co Fungicidal trifluorophenyl-triazolopyrimidines
US5994360A (en) 1997-07-14 1999-11-30 American Cyanamid Company Fungicidal 5-alkyl-triazolopyrimidines
US5986153A (en) 1997-09-30 1999-11-16 Phillips Petroleum Company Olefin color stabilization
US6020338A (en) 1998-02-11 2000-02-01 American Cyanamid Company Fungicidal 7-alkyl-triazolopyrimidines
US5981534A (en) 1998-09-25 1999-11-09 American Cyanamid Company Fungicidal 6-(2,6-difluoro-4-alkoxyphenyl)-triazolopyrimidines
ES2244183T3 (es) * 1998-03-23 2005-12-01 Basf Aktiengesellschaft 6-(2-halo-4-alcoxifenil)-triazolpirimidinas fungicidas.
US5986135A (en) 1998-09-25 1999-11-16 American Cyanamid Company Fungicidal trifluoromethylalkylamino-triazolopyrimidines
US5985883A (en) 1998-09-25 1999-11-16 American Cyanamid Company Fungicidal trichlorophenyl-triazolopyrimidines
JP2000103790A (ja) 1998-09-25 2000-04-11 American Cyanamid Co 殺菌・殺カビ性のトリハロフェニル―トリアゾロピリミジン類
US6242451B1 (en) 1998-09-25 2001-06-05 Klaus-Juergen Pees Fungicidal trihalophenyl-triazolopyrimidines
SK18412002A3 (sk) 2000-06-30 2003-06-03 Wyeth Použitie substituovaných triazolopyrimidínových derivátov a farmaceutický prostriedok s ich obsahom
WO2005030775A1 (en) * 2003-09-24 2005-04-07 Wyeth Holdings Corporation 6-[(substituted)phenyl]triazolopyrimidines as anticancer agents
CN101193884A (zh) * 2005-06-13 2008-06-04 惠氏公司 微管蛋白抑制剂和其制备方法

Also Published As

Publication number Publication date
DK1692137T3 (da) 2007-04-30
RU2006117023A (ru) 2008-01-20
PA8619401A1 (es) 2005-08-04
DE602004005239D1 (de) 2007-04-19
PE20050593A1 (es) 2005-09-27
JP2007513185A (ja) 2007-05-24
CN1890245A (zh) 2007-01-03
GT200400248A (es) 2005-09-14
AU2004297244A1 (en) 2005-06-23
US20050124635A1 (en) 2005-06-09
TW200522963A (en) 2005-07-16
ATE356128T1 (de) 2007-03-15
CR8435A (es) 2007-06-08
PL1692137T3 (pl) 2007-06-29
BRPI0417422A (pt) 2007-03-13
KR20060094984A (ko) 2006-08-30
US7396835B2 (en) 2008-07-08
ECSP066606A (es) 2006-10-25
MY179926A (en) 2020-11-19
ZA200604680B (en) 2009-04-29
DE602004005239T2 (de) 2007-12-20
WO2005056560A1 (en) 2005-06-23
AR046939A1 (es) 2006-01-04
ES2281850T3 (es) 2007-10-01
EP1692137A1 (en) 2006-08-23
CO5700827A2 (es) 2006-11-30
HK1090377A1 (en) 2006-12-22
IL175775A0 (en) 2006-09-05
EP1692137B1 (en) 2007-03-07
CA2546899A1 (en) 2005-06-23
NZ547471A (en) 2009-03-31

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