ATE356128T1 - Verfahren zur herstellung von tubulininhibitoren - Google Patents

Verfahren zur herstellung von tubulininhibitoren

Info

Publication number
ATE356128T1
ATE356128T1 AT04813203T AT04813203T ATE356128T1 AT E356128 T1 ATE356128 T1 AT E356128T1 AT 04813203 T AT04813203 T AT 04813203T AT 04813203 T AT04813203 T AT 04813203T AT E356128 T1 ATE356128 T1 AT E356128T1
Authority
AT
Austria
Prior art keywords
producing
tubulin inhibitors
tubulin
inhibitors
producing tubulin
Prior art date
Application number
AT04813203T
Other languages
English (en)
Inventor
Yanzhong Wu
Jean Schmid
Jay Thomas Afragola
David Michael Blum
Semiramis Ayral-Kaloustian
Original Assignee
Wyeth Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wyeth Corp filed Critical Wyeth Corp
Application granted granted Critical
Publication of ATE356128T1 publication Critical patent/ATE356128T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • A61P35/04Antineoplastic agents specific for metastasis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
AT04813203T 2003-12-08 2004-12-07 Verfahren zur herstellung von tubulininhibitoren ATE356128T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US52793103P 2003-12-08 2003-12-08

Publications (1)

Publication Number Publication Date
ATE356128T1 true ATE356128T1 (de) 2007-03-15

Family

ID=34676796

Family Applications (1)

Application Number Title Priority Date Filing Date
AT04813203T ATE356128T1 (de) 2003-12-08 2004-12-07 Verfahren zur herstellung von tubulininhibitoren

Country Status (29)

Country Link
US (1) US7396835B2 (de)
EP (1) EP1692137B1 (de)
JP (1) JP2007513185A (de)
KR (1) KR20060094984A (de)
CN (1) CN1890245A (de)
AR (1) AR046939A1 (de)
AT (1) ATE356128T1 (de)
AU (1) AU2004297244A1 (de)
BR (1) BRPI0417422A (de)
CA (1) CA2546899A1 (de)
CO (1) CO5700827A2 (de)
CR (1) CR8435A (de)
DE (1) DE602004005239T2 (de)
DK (1) DK1692137T3 (de)
EC (1) ECSP066606A (de)
ES (1) ES2281850T3 (de)
GT (1) GT200400248A (de)
HK (1) HK1090377A1 (de)
IL (1) IL175775A0 (de)
MY (1) MY179926A (de)
NO (1) NO20062492L (de)
NZ (1) NZ547471A (de)
PA (1) PA8619401A1 (de)
PE (1) PE20050593A1 (de)
PL (1) PL1692137T3 (de)
RU (1) RU2006117023A (de)
TW (1) TW200522963A (de)
WO (1) WO2005056560A1 (de)
ZA (1) ZA200604680B (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6255309B1 (en) * 1999-03-19 2001-07-03 American Cyanomid Co. Fungicidal trifluoromethylalkylamino-triazolopyrimidines
US7419982B2 (en) * 2003-09-24 2008-09-02 Wyeth Holdings Corporation Crystalline forms of 5-chloro-6-{2,6-difluoro-4-[3-(methylamino)propoxy]phenyl}-N-[(1S)-2,2,2-trifluoro-1-methylethyl][1,2,4]triazolo[1,5-a]pyrimidin-7-amine salts
TW200800959A (en) 2005-06-10 2008-01-01 Wyeth Corp Piperazine-piperidine antagonists and agonists of the 5-HT1a receptor
TW200808730A (en) * 2006-06-09 2008-02-16 Wyeth Corp Process for synthesizing piperazine-piperidine compounds
JP2010515669A (ja) * 2007-01-08 2010-05-13 ビーエーエスエフ ソシエタス・ヨーロピア 有害な植物病原菌類を防除するためのアゾロピリミジンの使用
EP3219207A1 (de) 2012-09-19 2017-09-20 The Trustees Of The University Of Pennsylvania Heterocyclische verbindungen und deren verwendung zur behandlung neurodegenerativer tauopathien
EP3758696A4 (de) 2018-03-02 2021-12-08 The Trustees of the University of Pennsylvania [1,2,4]triazolo[1,5-a]pyrimidin-verbindungen und verwendung davon zur stabilisierung von mikrotubuli

Family Cites Families (25)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TW224044B (de) 1991-12-30 1994-05-21 Shell Internat Res Schappej B V
US5593996A (en) * 1991-12-30 1997-01-14 American Cyanamid Company Triazolopyrimidine derivatives
JP2794510B2 (ja) * 1992-03-27 1998-09-10 富士写真フイルム株式会社 ハロゲン化銀写真感光材料
IL108747A (en) * 1993-03-04 1999-03-12 Shell Int Research Mushroom-killing preparations containing a history of 6 metamorphoses of 5 - 7 Dihalo - 1, 2 - 4 Triazlo [A-1,5] Pyrimidine Certain such new compounds and their preparation
IL108731A (en) * 1993-03-04 1997-03-18 Shell Int Research 6, N-DISUBSTITUTED-£1, 2, 4| TRIAZOLO-£1, 5-a| PYRIMIDINE- 7-AMINE DERIVATIVES, THEIR PREPARATION AND THEIR USE AS FUNGICIDES
RU2147584C1 (ru) * 1995-10-27 2000-04-20 Американ Цианамид Компани Способ получения дигалоидазолопиримидинов и способ получения дигидроксиазолопиримидинов
US5817663A (en) * 1996-10-07 1998-10-06 American Cyanamid Company Pentafluorophenylazolopyrimidines
US5750766A (en) * 1997-03-18 1998-05-12 American Cyanamid Company Process for the preparation of arylmalonates
DK0984919T3 (da) 1997-03-18 2003-05-12 Basf Ag Fremgangsmåde til fremstilling af arylmalonater
US6117876A (en) * 1997-04-14 2000-09-12 American Cyanamid Company Fungicidal trifluorophenyl-triazolopyrimidines
TWI252231B (en) 1997-04-14 2006-04-01 American Cyanamid Co Fungicidal trifluorophenyl-triazolopyrimidines
US5948783A (en) * 1997-04-14 1999-09-07 American Cyanamid Company Fungicidal trifluoromethylalkylamino-triazolopyrimidines
TW460476B (en) 1997-04-14 2001-10-21 American Cyanamid Co Fungicidal trifluoromethylalkylamino-triazolopyrimidines
US5994360A (en) * 1997-07-14 1999-11-30 American Cyanamid Company Fungicidal 5-alkyl-triazolopyrimidines
US5986153A (en) * 1997-09-30 1999-11-16 Phillips Petroleum Company Olefin color stabilization
US6020338A (en) * 1998-02-11 2000-02-01 American Cyanamid Company Fungicidal 7-alkyl-triazolopyrimidines
CA2324154C (en) * 1998-03-23 2008-03-18 American Cyanamid Company Fungicidal 6-(2-halo-4-alkoxyphenyl)-triazolopyrimidines
US5981534A (en) * 1998-09-25 1999-11-09 American Cyanamid Company Fungicidal 6-(2,6-difluoro-4-alkoxyphenyl)-triazolopyrimidines
JP2000103790A (ja) 1998-09-25 2000-04-11 American Cyanamid Co 殺菌・殺カビ性のトリハロフェニル―トリアゾロピリミジン類
US6242451B1 (en) * 1998-09-25 2001-06-05 Klaus-Juergen Pees Fungicidal trihalophenyl-triazolopyrimidines
US5985883A (en) * 1998-09-25 1999-11-16 American Cyanamid Company Fungicidal trichlorophenyl-triazolopyrimidines
US5986135A (en) 1998-09-25 1999-11-16 American Cyanamid Company Fungicidal trifluoromethylalkylamino-triazolopyrimidines
AU7306201A (en) 2000-06-30 2002-01-14 American Home Prod Substituted-triazolopyrimidines as anticancer agents
KR20060098368A (ko) * 2003-09-24 2006-09-18 와이어쓰 홀딩스 코포레이션 항암제로서의 6-[(치환된)페닐]트리아졸로피리미딘
CN101193884A (zh) * 2005-06-13 2008-06-04 惠氏公司 微管蛋白抑制剂和其制备方法

Also Published As

Publication number Publication date
PA8619401A1 (es) 2005-08-04
IL175775A0 (en) 2006-09-05
CA2546899A1 (en) 2005-06-23
AU2004297244A1 (en) 2005-06-23
DE602004005239T2 (de) 2007-12-20
BRPI0417422A (pt) 2007-03-13
GT200400248A (es) 2005-09-14
EP1692137A1 (de) 2006-08-23
NZ547471A (en) 2009-03-31
MY179926A (en) 2020-11-19
NO20062492L (no) 2006-07-03
EP1692137B1 (de) 2007-03-07
KR20060094984A (ko) 2006-08-30
PL1692137T3 (pl) 2007-06-29
RU2006117023A (ru) 2008-01-20
CR8435A (es) 2007-06-08
ZA200604680B (en) 2009-04-29
ES2281850T3 (es) 2007-10-01
WO2005056560A1 (en) 2005-06-23
CO5700827A2 (es) 2006-11-30
HK1090377A1 (en) 2006-12-22
CN1890245A (zh) 2007-01-03
TW200522963A (en) 2005-07-16
US20050124635A1 (en) 2005-06-09
AR046939A1 (es) 2006-01-04
ECSP066606A (es) 2006-10-25
US7396835B2 (en) 2008-07-08
DE602004005239D1 (de) 2007-04-19
DK1692137T3 (da) 2007-04-30
PE20050593A1 (es) 2005-09-27
JP2007513185A (ja) 2007-05-24

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