ATE432918T1 - Verfahren zur herstellung von cpla 2-inhibitoren - Google Patents
Verfahren zur herstellung von cpla 2-inhibitorenInfo
- Publication number
- ATE432918T1 ATE432918T1 AT04778654T AT04778654T ATE432918T1 AT E432918 T1 ATE432918 T1 AT E432918T1 AT 04778654 T AT04778654 T AT 04778654T AT 04778654 T AT04778654 T AT 04778654T AT E432918 T1 ATE432918 T1 AT E432918T1
- Authority
- AT
- Austria
- Prior art keywords
- cpla
- inhibitors
- producing
- producing cpla
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/38—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reaction of ammonia or amines with sulfonic acids, or with esters, anhydrides, or halides thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C303/00—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides
- C07C303/36—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids
- C07C303/40—Preparation of esters or amides of sulfuric acids; Preparation of sulfonic acids or of their esters, halides, anhydrides or amides of amides of sulfonic acids by reactions not involving the formation of sulfonamide groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/01—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms
- C07C311/12—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings
- C07C311/13—Sulfonamides having sulfur atoms of sulfonamide groups bound to acyclic carbon atoms of an unsaturated carbon skeleton containing rings the carbon skeleton containing six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Health & Medical Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Indole Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US49000503P | 2003-07-25 | 2003-07-25 | |
PCT/US2004/023247 WO2005012238A1 (en) | 2003-07-25 | 2004-07-19 | Process for the preparation of cpla2 inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE432918T1 true ATE432918T1 (de) | 2009-06-15 |
Family
ID=34115341
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT04778654T ATE432918T1 (de) | 2003-07-25 | 2004-07-19 | Verfahren zur herstellung von cpla 2-inhibitoren |
Country Status (14)
Country | Link |
---|---|
US (2) | US6891065B2 (de) |
EP (1) | EP1648861B1 (de) |
JP (1) | JP4607877B2 (de) |
CN (1) | CN100577640C (de) |
AR (1) | AR045089A1 (de) |
AT (1) | ATE432918T1 (de) |
AU (1) | AU2004261567A1 (de) |
BR (1) | BRPI0412904A (de) |
CA (1) | CA2528174C (de) |
DE (1) | DE602004021388D1 (de) |
ES (1) | ES2325265T3 (de) |
MX (1) | MXPA06000406A (de) |
TW (1) | TW200510305A (de) |
WO (1) | WO2005012238A1 (de) |
Families Citing this family (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7713964B2 (en) | 2001-12-03 | 2010-05-11 | Wyeth Llc | Methods for treating asthmatic conditions |
US7605156B2 (en) | 2001-12-03 | 2009-10-20 | Wyeth | Methods for the use of inhibitors of cytosolic phospholipase A2 |
TW200510305A (en) | 2003-07-25 | 2005-03-16 | Wyeth Corp | Process for the preparation of CPLA2 inhibitors |
US7342119B2 (en) * | 2003-09-30 | 2008-03-11 | Wyeth Holdings Corporation | Process for the synthesis of a CPLA2 inhibitor |
HN2004000536A (es) * | 2003-12-16 | 2009-02-18 | Wyeth Corp | Un procediemiento de sintesis para la alquilacion reductiva de la posicon c-3 de indoles |
AR053410A1 (es) * | 2004-08-19 | 2007-05-09 | Wyeth Corp | Proceso para la sintesis de indoles n-alquilados c-2, c-3 sustituidos. compuestos intermediarios |
TW200718687A (en) | 2005-05-27 | 2007-05-16 | Wyeth Corp | Inhibitors of cytosolic phospholipase A2 |
KR100746342B1 (ko) | 2006-04-10 | 2007-08-03 | 한국과학기술원 | 구리 촉매 존재하에서 n―설포닐아미드 화합물의 제조방법 |
CN100363341C (zh) * | 2006-05-12 | 2008-01-23 | 北京化工大学 | 旋光性n-炔丙磺酰胺聚合物及其制备方法 |
WO2008055148A2 (en) * | 2006-10-31 | 2008-05-08 | Wyeth | Semi-solid formulations of phospholipase enzyme inhibitors |
AU2007313706A1 (en) * | 2006-10-31 | 2008-05-08 | Wyeth | Liquid formulations of phospholipase enzyme inhibitors |
US8113207B2 (en) * | 2008-08-22 | 2012-02-14 | Kimberly-Clark Worldwide, Inc. | Self-conforming sound attenuation earplug |
CN102617558A (zh) * | 2012-03-26 | 2012-08-01 | 上海泛凯生物医药科技有限公司 | 一种维拉佐酮的制备方法 |
CN110437125B (zh) * | 2019-09-06 | 2021-03-12 | 苏州旺山旺水生物医药有限公司 | 一种Tezacaftor中间体II的制备方法 |
Family Cites Families (31)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5461075A (en) | 1988-06-17 | 1995-10-24 | The Procter & Gamble Company | Use of vanilloids for the prevention of lesions due to herpes simplex infections |
US5186736A (en) | 1988-08-02 | 1993-02-16 | Hoechst Aktiengesellschaft | Heterocyclic N-acylsulfonamides and their use as herbicides or growth regulators |
DE3826230A1 (de) | 1988-08-02 | 1990-02-08 | Hoechst Ag | Heterocyclische n-acylsufonamide, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als herbizide oder wachstumsregulatoren |
JPH02115157A (ja) * | 1988-10-24 | 1990-04-27 | Hokko Chem Ind Co Ltd | スルホニルグリシン誘導体および除草剤 |
CA2017383A1 (en) | 1989-06-08 | 1990-12-08 | Raymond R. Martodam | Use of vanilloids for the treatment of respiratory diseases or disorders |
DE3935277A1 (de) | 1989-10-24 | 1991-05-02 | Hoechst Ag | Sulfonierte heterocyclische carboxamide, verfahren zu ihrer herstellung, sie enthaltende mittel und ihre verwendung als herbizide oder wachstumsregulatoren |
GB9201755D0 (en) | 1992-01-28 | 1992-03-11 | British Bio Technology | Compounds |
EP0736014B1 (de) | 1993-12-20 | 2001-04-04 | Bayer Ag | N-cyanoaryl-stickstoffheterocyclen mit schwefelhaltigen gruppierungen |
DE4431218A1 (de) | 1994-09-02 | 1996-03-07 | Bayer Ag | Substituierte Pyrimidin(thi)one |
DE19528305A1 (de) | 1995-08-02 | 1997-02-06 | Bayer Ag | Substituierte Phenyluracile |
DE19601626A1 (de) | 1996-01-18 | 1997-07-24 | Bayer Ag | Substituierte N-Aryl-Stickstoffheterocyclen |
DE19606594A1 (de) | 1996-02-22 | 1997-08-28 | Bayer Ag | Substituierte 2-Aryl-1,2,4-triazin-3,5-di(thi)one |
CA2264020A1 (en) * | 1996-08-26 | 1998-03-05 | Jean Bemis | Inhibitors of phospholipase enzymes |
CA2322161A1 (en) * | 1998-02-25 | 1999-09-02 | Yibin Xiang | Inhibitors of phospholipase enzymes |
GB9912411D0 (en) | 1999-05-28 | 1999-07-28 | Pfizer Ltd | Compounds useful in therapy |
WO2002002517A1 (fr) * | 2000-07-05 | 2002-01-10 | Ajinomoto Co.,Inc. | Derives d'acylsulfonamides |
DE10043790A1 (de) | 2000-09-06 | 2002-03-14 | Bayer Ag | Substituierte 1-Aryl-pyridin-2-(thi)one |
WO2002044126A2 (en) | 2000-11-28 | 2002-06-06 | Guilford Pharmaceuticals Inc. | Bisubstituted carbocyclic cyclophilin binding compounds and theirus |
JP2004532187A (ja) | 2001-01-25 | 2004-10-21 | ギルフォード ファーマシュウティカルズ インコーポレイテッド | 三置換カルボサイクリックサイクロフィリン結合化合物とその用途 |
CA2453259A1 (en) | 2001-09-06 | 2003-03-20 | Syngenta Participations Ag | Herbicidal n-alkylsulfonamino derivatives |
US6797708B2 (en) * | 2001-12-03 | 2004-09-28 | Wyeth | Inhibitors of cytosolic phospholipase A2 |
US6635771B2 (en) * | 2001-12-03 | 2003-10-21 | Wyeth | N-benzhydryl indole compounds |
US7713964B2 (en) | 2001-12-03 | 2010-05-11 | Wyeth Llc | Methods for treating asthmatic conditions |
US6984735B2 (en) | 2001-12-03 | 2006-01-10 | Wyeth | Process for making an aldehyde |
US7101875B2 (en) | 2001-12-03 | 2006-09-05 | Wyeth | Methods for treating arthritic disorders |
US7605156B2 (en) | 2001-12-03 | 2009-10-20 | Wyeth | Methods for the use of inhibitors of cytosolic phospholipase A2 |
WO2003048122A2 (en) * | 2001-12-03 | 2003-06-12 | Wyeth | Inhibitors of cytosolic phospholipase a2 |
TW200510305A (en) | 2003-07-25 | 2005-03-16 | Wyeth Corp | Process for the preparation of CPLA2 inhibitors |
US7582771B2 (en) | 2003-09-03 | 2009-09-01 | Wyeth | Process for the synthesis of cPLA2 inhibitors |
US7342119B2 (en) | 2003-09-30 | 2008-03-11 | Wyeth Holdings Corporation | Process for the synthesis of a CPLA2 inhibitor |
HN2004000536A (es) * | 2003-12-16 | 2009-02-18 | Wyeth Corp | Un procediemiento de sintesis para la alquilacion reductiva de la posicon c-3 de indoles |
-
2004
- 2004-06-29 TW TW093119031A patent/TW200510305A/zh unknown
- 2004-07-19 BR BRPI0412904-0A patent/BRPI0412904A/pt not_active IP Right Cessation
- 2004-07-19 CN CN200480018618A patent/CN100577640C/zh not_active Expired - Fee Related
- 2004-07-19 EP EP04778654A patent/EP1648861B1/de not_active Expired - Lifetime
- 2004-07-19 CA CA2528174A patent/CA2528174C/en not_active Expired - Lifetime
- 2004-07-19 AT AT04778654T patent/ATE432918T1/de not_active IP Right Cessation
- 2004-07-19 AU AU2004261567A patent/AU2004261567A1/en not_active Abandoned
- 2004-07-19 MX MXPA06000406A patent/MXPA06000406A/es active IP Right Grant
- 2004-07-19 DE DE602004021388T patent/DE602004021388D1/de not_active Expired - Lifetime
- 2004-07-19 WO PCT/US2004/023247 patent/WO2005012238A1/en active Application Filing
- 2004-07-19 ES ES04778654T patent/ES2325265T3/es not_active Expired - Lifetime
- 2004-07-19 JP JP2006521893A patent/JP4607877B2/ja not_active Expired - Fee Related
- 2004-07-21 US US10/896,318 patent/US6891065B2/en not_active Expired - Fee Related
- 2004-07-23 AR ARP040102620A patent/AR045089A1/es unknown
-
2005
- 2005-03-08 US US11/076,117 patent/US7259277B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
BRPI0412904A (pt) | 2006-09-26 |
CN1816522A (zh) | 2006-08-09 |
US20050020858A1 (en) | 2005-01-27 |
CA2528174C (en) | 2012-03-13 |
US6891065B2 (en) | 2005-05-10 |
US7259277B2 (en) | 2007-08-21 |
US20050159613A1 (en) | 2005-07-21 |
AU2004261567A1 (en) | 2005-02-10 |
TW200510305A (en) | 2005-03-16 |
JP2007500190A (ja) | 2007-01-11 |
CN100577640C (zh) | 2010-01-06 |
JP4607877B2 (ja) | 2011-01-05 |
DE602004021388D1 (de) | 2009-07-16 |
AR045089A1 (es) | 2005-10-12 |
CA2528174A1 (en) | 2005-02-10 |
MXPA06000406A (es) | 2006-03-17 |
ES2325265T3 (es) | 2009-08-31 |
WO2005012238A1 (en) | 2005-02-10 |
EP1648861A1 (de) | 2006-04-26 |
EP1648861B1 (de) | 2009-06-03 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60221399D1 (de) | Verfahren zur herstellung von mitteldistillaten | |
ATE340819T1 (de) | Verfahren zur herstellung von polyamiden | |
ATE403641T1 (de) | Verfahren zur herstellung von o- desmethylvenlafaxin | |
ATE515500T1 (de) | Verfahren zur herstellung von telmisartan | |
ATA11912002A (de) | Verfahren zur herstellung von fälschungssicheren identifikationsmerkmalen | |
DE60230908D1 (de) | Verfahren zur herstellung von polyarylenethern | |
ATE374463T1 (de) | Verfahren zur herstellung von oxazolidinonen | |
ATE308524T1 (de) | Verfahren zur herstellung von aripiprazole | |
ATE432918T1 (de) | Verfahren zur herstellung von cpla 2-inhibitoren | |
DE50308650D1 (de) | Verfahren zur herstellung von cellulosecarbamatformkörpern | |
ATE296287T1 (de) | Verfahren zur herstellung von repaglinide | |
DE602004022134D1 (de) | Verfahren zur herstellung von dinitrilen | |
ATE553103T1 (de) | Verfahren zur herstellung von (s)-pantoprazol | |
ATE336478T1 (de) | Verfahren zur herstellung von benzophenonen | |
ATE441662T1 (de) | Verfahren zur herstellung von echinocandinderivaten | |
ATE453619T1 (de) | Verfahren zur herstellung von hydroperoxiden | |
DE50303611D1 (de) | Verfahren zur herstellung von polyisobuten | |
DE60210911D1 (de) | Verfahren zur Herstellung von dehnungserfassenden Vorrichtungen | |
DE50200870D1 (de) | Verfahren zur herstellung von hydroxyalkylpolysiloxanen | |
ATE402138T1 (de) | Verfahren zur herstellung von 2- aminoindanderivaten | |
DE502004004318D1 (de) | Verfahren zur herstellung von metall-matrix-verbundwerkstoffen | |
ATE349442T1 (de) | Verbessertes verfahren zur herstellung von alpha- polymorphem eletriptan hydrobromid | |
ATA332003A (de) | Verfahren zur herstellung von metallschaumkörpern | |
ATE356128T1 (de) | Verfahren zur herstellung von tubulininhibitoren | |
ATE471941T1 (de) | Verfahren zur herstellung von thiazolopyrimidinen |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
RER | Ceased as to paragraph 5 lit. 3 law introducing patent treaties |