ATE440888T1 - Verfahren zur herstellung von glatiramer - Google Patents

Verfahren zur herstellung von glatiramer

Info

Publication number
ATE440888T1
ATE440888T1 AT05824006T AT05824006T ATE440888T1 AT E440888 T1 ATE440888 T1 AT E440888T1 AT 05824006 T AT05824006 T AT 05824006T AT 05824006 T AT05824006 T AT 05824006T AT E440888 T1 ATE440888 T1 AT E440888T1
Authority
AT
Austria
Prior art keywords
glatiramer
producing
producing glatiramer
Prior art date
Application number
AT05824006T
Other languages
English (en)
Inventor
Anup Ray
Hiren Patel
Johannes Ludescher
Mariappan Anbazhagan
Mahendra Patel
Ingolf Macher
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Application granted granted Critical
Publication of ATE440888T1 publication Critical patent/ATE440888T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G69/00—Macromolecular compounds obtained by reactions forming a carboxylic amide link in the main chain of the macromolecule
    • C08G69/02—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids
    • C08G69/08—Polyamides derived from amino-carboxylic acids or from polyamines and polycarboxylic acids derived from amino-carboxylic acids
    • C08G69/10—Alpha-amino-carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/001—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof by chemical synthesis
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Polymers & Plastics (AREA)
  • Molecular Biology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Rheumatology (AREA)
  • Transplantation (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyamides (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT05824006T 2004-10-29 2005-10-27 Verfahren zur herstellung von glatiramer ATE440888T1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US62334604P 2004-10-29 2004-10-29
US65153505P 2005-02-09 2005-02-09
US65137205P 2005-02-09 2005-02-09
US72390105P 2005-10-05 2005-10-05
PCT/US2005/039003 WO2006050122A1 (en) 2004-10-29 2005-10-27 Processes for preparing glatiramer

Publications (1)

Publication Number Publication Date
ATE440888T1 true ATE440888T1 (de) 2009-09-15

Family

ID=36046637

Family Applications (1)

Application Number Title Priority Date Filing Date
AT05824006T ATE440888T1 (de) 2004-10-29 2005-10-27 Verfahren zur herstellung von glatiramer

Country Status (14)

Country Link
US (5) US20060154862A1 (de)
EP (1) EP1807467B1 (de)
JP (1) JP5297653B2 (de)
CN (1) CN101044188B (de)
AR (1) AR052321A1 (de)
AT (1) ATE440888T1 (de)
AU (1) AU2005302500B2 (de)
CA (1) CA2583589C (de)
DE (1) DE602005016292D1 (de)
ES (1) ES2331015T3 (de)
IL (2) IL182581A (de)
SI (1) SI1807467T1 (de)
TW (1) TWI307349B (de)
WO (1) WO2006050122A1 (de)

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AU2005302500B2 (en) * 2004-10-29 2008-11-27 Sandoz Ag Processes for preparing glatiramer
WO2007081975A2 (en) * 2006-01-11 2007-07-19 Teva Pharmaceutical Industries, Ltd. Method of treating multiple sclerosis
DE602007003848D1 (de) * 2006-07-05 2010-01-28 Momenta Pharmaceuticals Inc Verbessertes verfahren zur herstellung von copolymer-1
AU2008265692A1 (en) 2007-06-21 2008-12-24 Momenta Pharmaceuticals, Inc. Copolymer assay
US20090035816A1 (en) * 2007-08-02 2009-02-05 Scinopharm Taiwan Ltd. Process for the preparation of a polypeptide
ES2449865T5 (es) 2008-04-16 2022-11-18 Momenta Pharmaceuticals Inc Análisis de composiciones de copolímeros de aminoácidos
CA2733500A1 (en) * 2008-08-07 2010-02-11 Scinopharm Taiwan, Ltd. Synthesis of glatiramer acetate
WO2010017075A1 (en) 2008-08-07 2010-02-11 Sigma-Aldrich Co. Preparation of low molecular weight polylysine and polyornithine in high yield
US9617313B2 (en) 2008-12-24 2017-04-11 Synthon Bv Process for purifying a polymer mixture
WO2010115175A1 (en) 2009-04-03 2010-10-07 Momenta Pharmaceticals, Inc. Control of copolymer compositions
US8920373B2 (en) 2009-07-15 2014-12-30 Teva Pharmaceutical Industries, Ltd. Reduced volume formulation of glatiramer acetate and methods of administration
ATE549013T1 (de) * 2009-07-15 2012-03-15 Teva Pharma Formulierung von glatirameracetat mit verringertem volumen und verabreichungsverfahren
EA019998B9 (ru) 2009-08-20 2016-01-29 Йеда Рисерч Энд Дивелопмент Ко. Лтд. Терапия глатирамером ацетатом с низкой кратностью
AU2010322038A1 (en) * 2009-11-17 2012-06-14 Ares Trading S.A. Methods for improving the design, bioavailability, and efficacy of random sequence polymer compositions via serum protein-based detection of random sequence polymer compositions
USRE49251E1 (en) 2010-01-04 2022-10-18 Mapi Pharma Ltd. Depot systems comprising glatiramer or pharmacologically acceptable salt thereof
US8759302B2 (en) 2010-03-16 2014-06-24 Teva Pharmaceutical Industries, Ltd. Methods of treating a subject afflicted with an autoimmune disease using predictive biomarkers of clinical response to glatiramer acetate therapy in multiple sclerosis
KR20130062936A (ko) * 2010-04-27 2013-06-13 닥터 레디스 레보러터리즈 리미티드 폴리펩티드 및 그의 염의 제조
WO2012016042A2 (en) * 2010-07-29 2012-02-02 Dr. Reddy's Laboratories Ltd. Glatiramer acetate molecular weight markers
PL2627669T3 (pl) 2010-10-11 2017-02-28 Teva Pharmaceutical Industries Ltd. Biomarkery cytokinowe jako biomarkery prognostyczne odpowiedzi klinicznej na octan glatirameru
RU2604521C2 (ru) 2011-02-14 2016-12-10 Юсв Прайвит Лимитед Сополимер-1, способы его получения и аналитические методы
WO2012114167A1 (en) * 2011-02-24 2012-08-30 Biocon Limited Processes for the preparation of glatiramer acetate
WO2013009864A1 (en) 2011-07-11 2013-01-17 Momenta Pharmaceuticals, Inc. Structure assessment of heterogeneous polypeptide mixtures
WO2013009885A2 (en) 2011-07-11 2013-01-17 Momenta Pharmaceuticals, Inc. Evaluation of copolymer diethylamide
US8575198B1 (en) 2011-09-07 2013-11-05 Momenta Pharmaceuticals, Inc. In-process control for the manufacture of glatiramer acetate
EP2765857A4 (de) 2011-10-10 2015-12-09 Teva Pharma Einzelnukleotidpolymorphismen zur vorhersage des klinischen ansprechens auf glatirameracetat
JP2014532692A (ja) * 2011-11-03 2014-12-08 バイオコン リミテッド ランダムポリペプチドの調製プロセス、及び、酢酸ガラティラメルを製造するためのガイダンスツールとして円偏光二色性を用いること
US20140045740A1 (en) * 2012-08-13 2014-02-13 Momenta Pharmaceuticals, Inc. Analysis of glatiramer acetate
US9155775B1 (en) 2015-01-28 2015-10-13 Teva Pharmaceutical Industries, Ltd. Process for manufacturing glatiramer acetate product
DK3433430T3 (da) 2016-03-23 2022-09-05 Alm Holding Co Batch-asfaltblandeanlæg
US12097292B2 (en) 2016-08-28 2024-09-24 Mapi Pharma Ltd. Process for preparing microparticles containing glatiramer acetate
AU2017319728B2 (en) 2016-08-31 2024-09-05 Mapi Pharma Ltd Depot systems comprising glatiramer acetate
MX2019010174A (es) 2017-03-26 2019-10-15 Mapi Pharma Ltd Sistemas de deposito de glatiramer para el tratamiento de formas progresivas de esclerosis multiple.
CN107082796B (zh) * 2017-05-02 2020-06-09 江苏大学 一种提纯蛋白酶解物中小分子多肽的方法
GB2579600B (en) 2018-12-05 2023-07-05 Byotrol Plc Anti-viral composition
BR112021026863A2 (pt) 2019-07-01 2022-03-03 Alm Holding Co Sistemas para processar material e para suprimir micro-ondas, métodos para processar material, para prover de modo portável material processado sob demanda e para fazer uma mistura betuminosa, produto, e, aparelho para tratar material

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Also Published As

Publication number Publication date
JP5297653B2 (ja) 2013-09-25
US20100174048A1 (en) 2010-07-08
EP1807467A1 (de) 2007-07-18
US20080021200A1 (en) 2008-01-24
JP2008518930A (ja) 2008-06-05
CA2583589A1 (en) 2006-05-11
US20100234566A1 (en) 2010-09-16
DE602005016292D1 (de) 2009-10-08
AU2005302500A1 (en) 2006-05-11
IL233618A0 (en) 2014-08-31
TWI307349B (en) 2009-03-11
TW200634051A (en) 2006-10-01
IL182581A (en) 2015-09-24
CA2583589C (en) 2012-04-24
ES2331015T3 (es) 2009-12-18
CN101044188A (zh) 2007-09-26
IL233618A (en) 2016-05-31
WO2006050122A1 (en) 2006-05-11
US20060154862A1 (en) 2006-07-13
AR052321A1 (es) 2007-03-14
SI1807467T1 (sl) 2009-12-31
EP1807467B1 (de) 2009-08-26
IL182581A0 (en) 2007-07-24
AU2005302500B2 (en) 2008-11-27
US8729229B2 (en) 2014-05-20
CN101044188B (zh) 2010-08-04
US8536305B2 (en) 2013-09-17
US20100234272A1 (en) 2010-09-16

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