ATE549314T1 - Verfahren zur herstellung von 4-aminochinazolinen - Google Patents
Verfahren zur herstellung von 4-aminochinazolinenInfo
- Publication number
- ATE549314T1 ATE549314T1 AT05854269T AT05854269T ATE549314T1 AT E549314 T1 ATE549314 T1 AT E549314T1 AT 05854269 T AT05854269 T AT 05854269T AT 05854269 T AT05854269 T AT 05854269T AT E549314 T1 ATE549314 T1 AT E549314T1
- Authority
- AT
- Austria
- Prior art keywords
- aminoquinazolines
- producing
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D265/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom and one oxygen atom as the only ring hetero atoms
- C07D265/04—1,3-Oxazines; Hydrogenated 1,3-oxazines
- C07D265/12—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems
- C07D265/14—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D265/24—1,3-Oxazines; Hydrogenated 1,3-oxazines condensed with carbocyclic rings or ring systems condensed with one six-membered ring with hetero atoms directly attached in positions 2 and 4
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/517—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with carbocyclic ring systems, e.g. quinazoline, perimidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C271/00—Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
- C07C271/06—Esters of carbamic acids
- C07C271/40—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings
- C07C271/58—Esters of carbamic acids having oxygen atoms of carbamate groups bound to carbon atoms of six-membered aromatic rings with the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/88—Oxygen atoms
- C07D239/91—Oxygen atoms with aryl or aralkyl radicals attached in position 2 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
- C07D239/72—Quinazolines; Hydrogenated quinazolines
- C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
- C07D239/94—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US63727804P | 2004-12-17 | 2004-12-17 | |
| PCT/US2005/045506 WO2006066044A2 (en) | 2004-12-17 | 2005-12-15 | Processes for producing 4-aminoquinazolines |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE549314T1 true ATE549314T1 (de) | 2012-03-15 |
Family
ID=36588571
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT05854269T ATE549314T1 (de) | 2004-12-17 | 2005-12-15 | Verfahren zur herstellung von 4-aminochinazolinen |
Country Status (18)
| Country | Link |
|---|---|
| US (1) | US20060166963A1 (de) |
| EP (2) | EP1828150B1 (de) |
| JP (2) | JP5030787B2 (de) |
| KR (1) | KR20070091660A (de) |
| CN (1) | CN101111487A (de) |
| AR (1) | AR053317A1 (de) |
| AT (1) | ATE549314T1 (de) |
| AU (1) | AU2005316454B2 (de) |
| BR (1) | BRPI0519600A2 (de) |
| CA (1) | CA2591588A1 (de) |
| ES (1) | ES2382200T3 (de) |
| IL (1) | IL183983A (de) |
| MX (1) | MX2007007446A (de) |
| PL (1) | PL382927A1 (de) |
| RU (1) | RU2007127315A (de) |
| TW (1) | TW200635905A (de) |
| WO (1) | WO2006066044A2 (de) |
| ZA (1) | ZA200704972B (de) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US7713983B2 (en) * | 2003-03-03 | 2010-05-11 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
| CL2004000409A1 (es) * | 2003-03-03 | 2005-01-07 | Vertex Pharma | Compuestos derivados de 2-(cilo sustituido)-1-(amino u oxi sustituido)-quinazolina, inhibidores de canales ionicos de sodio y calcio dependientes de voltaje; composicion farmaceutica; y uso del compuesto en el tratamiento de dolor agudo, cronico, neu |
| US8283354B2 (en) * | 2004-09-02 | 2012-10-09 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
| US7718658B2 (en) * | 2004-09-02 | 2010-05-18 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
| US7928107B2 (en) * | 2004-09-02 | 2011-04-19 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
| CA2628650A1 (en) * | 2005-11-14 | 2007-05-24 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of voltage gated ion channels |
| WO2007071055A1 (en) * | 2005-12-21 | 2007-06-28 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| EP2099458A4 (de) | 2006-12-01 | 2011-05-11 | Harvard College | Verbindungen und verfahren zur enzym-vermittelten tumordarstellung und therapie |
| US8786436B2 (en) * | 2009-08-31 | 2014-07-22 | Omron Corporation | Multiple optical axis photoelectric sensor |
| CN106632088B (zh) * | 2015-10-30 | 2019-04-19 | 华南理工大学 | 一种基于喹唑啉酮类化合物的聚集诱导发光探针及其制备方法和应用 |
Family Cites Families (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3637693A (en) * | 1968-07-12 | 1972-01-25 | Du Pont | Hydroxyarylquinazolines and their use as uv-absorbers |
| US3819628A (en) * | 1972-07-31 | 1974-06-25 | Sandoz Ag | 2-phenyl-4-substituted amino-quinazolines and nitrates thereof |
| DE19756388A1 (de) * | 1997-12-18 | 1999-06-24 | Hoechst Marion Roussel De Gmbh | Substituierte 2-Aryl-4-amino-chinazoline |
| US6184226B1 (en) * | 1998-08-28 | 2001-02-06 | Scios Inc. | Quinazoline derivatives as inhibitors of P-38 α |
| US6608053B2 (en) * | 2000-04-27 | 2003-08-19 | Yamanouchi Pharmaceutical Co., Ltd. | Fused heteroaryl derivatives |
| CN1466754A (zh) * | 2000-09-29 | 2004-01-07 | ���µ�����ҵ��ʽ���� | 光盘装置 |
| US7713983B2 (en) * | 2003-03-03 | 2010-05-11 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
| CL2004000409A1 (es) * | 2003-03-03 | 2005-01-07 | Vertex Pharma | Compuestos derivados de 2-(cilo sustituido)-1-(amino u oxi sustituido)-quinazolina, inhibidores de canales ionicos de sodio y calcio dependientes de voltaje; composicion farmaceutica; y uso del compuesto en el tratamiento de dolor agudo, cronico, neu |
| DE602004014347D1 (de) * | 2003-03-12 | 2008-07-24 | Millennium Pharm Inc | Chinazolin-derivate als tgf-beta-inhibitoren |
| US8283354B2 (en) * | 2004-09-02 | 2012-10-09 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
| US7718658B2 (en) * | 2004-09-02 | 2010-05-18 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of ion channels |
| CA2628650A1 (en) * | 2005-11-14 | 2007-05-24 | Vertex Pharmaceuticals Incorporated | Quinazolines useful as modulators of voltage gated ion channels |
-
2005
- 2005-12-15 CA CA002591588A patent/CA2591588A1/en not_active Abandoned
- 2005-12-15 AT AT05854269T patent/ATE549314T1/de active
- 2005-12-15 CN CNA2005800475989A patent/CN101111487A/zh active Pending
- 2005-12-15 RU RU2007127315/04A patent/RU2007127315A/ru not_active Application Discontinuation
- 2005-12-15 US US11/304,238 patent/US20060166963A1/en not_active Abandoned
- 2005-12-15 WO PCT/US2005/045506 patent/WO2006066044A2/en active Application Filing
- 2005-12-15 ZA ZA200704972A patent/ZA200704972B/xx unknown
- 2005-12-15 AU AU2005316454A patent/AU2005316454B2/en not_active Expired - Fee Related
- 2005-12-15 PL PL382927A patent/PL382927A1/pl not_active Application Discontinuation
- 2005-12-15 ES ES05854269T patent/ES2382200T3/es active Active
- 2005-12-15 JP JP2007546915A patent/JP5030787B2/ja not_active Expired - Fee Related
- 2005-12-15 EP EP05854269A patent/EP1828150B1/de not_active Not-in-force
- 2005-12-15 MX MX2007007446A patent/MX2007007446A/es not_active Application Discontinuation
- 2005-12-15 EP EP10181554A patent/EP2366696A1/de not_active Withdrawn
- 2005-12-15 KR KR1020077016333A patent/KR20070091660A/ko not_active Application Discontinuation
- 2005-12-15 BR BRPI0519600-0A patent/BRPI0519600A2/pt not_active IP Right Cessation
- 2005-12-16 TW TW094144956A patent/TW200635905A/zh unknown
- 2005-12-16 AR ARP050105321A patent/AR053317A1/es not_active Application Discontinuation
-
2007
- 2007-06-17 IL IL183983A patent/IL183983A/en not_active IP Right Cessation
-
2011
- 2011-12-20 JP JP2011278926A patent/JP2012056968A/ja not_active Withdrawn
Also Published As
| Publication number | Publication date |
|---|---|
| PL382927A1 (pl) | 2008-02-04 |
| RU2007127315A (ru) | 2009-01-27 |
| BRPI0519600A2 (pt) | 2009-02-25 |
| CN101111487A (zh) | 2008-01-23 |
| EP1828150B1 (de) | 2012-03-14 |
| ZA200704972B (en) | 2008-09-25 |
| JP2012056968A (ja) | 2012-03-22 |
| ES2382200T3 (es) | 2012-06-06 |
| AU2005316454B2 (en) | 2012-09-06 |
| US20060166963A1 (en) | 2006-07-27 |
| WO2006066044A3 (en) | 2007-05-10 |
| AR053317A1 (es) | 2007-05-02 |
| AU2005316454A1 (en) | 2006-06-22 |
| TW200635905A (en) | 2006-10-16 |
| CA2591588A1 (en) | 2006-06-22 |
| EP2366696A1 (de) | 2011-09-21 |
| WO2006066044A2 (en) | 2006-06-22 |
| MX2007007446A (es) | 2008-01-14 |
| IL183983A0 (en) | 2007-10-31 |
| JP5030787B2 (ja) | 2012-09-19 |
| EP1828150A2 (de) | 2007-09-05 |
| KR20070091660A (ko) | 2007-09-11 |
| IL183983A (en) | 2012-04-30 |
| JP2008524238A (ja) | 2008-07-10 |
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