NO20055891L - Kinazolinderivater som aurorakinaseinhibitorer - Google Patents
Kinazolinderivater som aurorakinaseinhibitorerInfo
- Publication number
- NO20055891L NO20055891L NO20055891A NO20055891A NO20055891L NO 20055891 L NO20055891 L NO 20055891L NO 20055891 A NO20055891 A NO 20055891A NO 20055891 A NO20055891 A NO 20055891A NO 20055891 L NO20055891 L NO 20055891L
- Authority
- NO
- Norway
- Prior art keywords
- quinazoline derivatives
- aurorakinase
- inhibitors
- treatment
- well
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/02—Antineoplastic agents specific for leukemia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing three or more hetero rings
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Hematology (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Abstract
Kinazolin-derivater med formel (I) for anvendelse ved behandling av proliferative sykdommer så som kreft, og ved fremstilling av medikamenter for anvendelse ved behandling av proliferative sykdommer, samt fremgangsmåter for fremstilling av dem, så vel som farmasøytiske preparater som inneholder dem som aktiv bestanddel.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP03291463 | 2003-06-17 | ||
PCT/GB2004/002564 WO2004113324A1 (en) | 2003-06-17 | 2004-06-14 | Chinazoline derivatives as aurora kinase inhibitors |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20055891L true NO20055891L (no) | 2006-02-07 |
Family
ID=33522456
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20055891A NO20055891L (no) | 2003-06-17 | 2005-12-12 | Kinazolinderivater som aurorakinaseinhibitorer |
Country Status (16)
Country | Link |
---|---|
US (1) | US20060178382A1 (no) |
EP (1) | EP1644361A1 (no) |
JP (1) | JP2006527748A (no) |
KR (1) | KR20060011891A (no) |
CN (1) | CN1835945A (no) |
AR (1) | AR045694A1 (no) |
AU (1) | AU2004249477A1 (no) |
BR (1) | BRPI0411503A (no) |
CA (1) | CA2529250A1 (no) |
IL (1) | IL172375A0 (no) |
MX (1) | MXPA05013825A (no) |
NO (1) | NO20055891L (no) |
TW (1) | TW200505452A (no) |
UY (1) | UY28366A1 (no) |
WO (1) | WO2004113324A1 (no) |
ZA (1) | ZA200510257B (no) |
Families Citing this family (20)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2301981T3 (es) * | 2003-04-16 | 2008-07-01 | Astrazeneca Ab | Derivados de quinazolina para el tratamiento del cancer. |
EP1635837B1 (en) * | 2003-06-02 | 2008-07-16 | AstraZeneca AB | (3-((quinazolin-4-yl)amino)-1h-pyrazol-1-yl)acetamide derivatives and related compounds as aurora kinase inhibitors for the treatment of proliferative diseases such as cancer |
AU2005293336B2 (en) | 2004-10-12 | 2009-05-28 | Astrazeneca Ab | Quinazoline derivatives |
EP1812439B2 (en) | 2004-10-15 | 2017-12-06 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
US7358256B2 (en) * | 2005-03-28 | 2008-04-15 | Bristol-Myers Squibb Company | ATP competitive kinase inhibitors |
US8119655B2 (en) | 2005-10-07 | 2012-02-21 | Takeda Pharmaceutical Company Limited | Kinase inhibitors |
UY30183A1 (es) | 2006-03-02 | 2007-10-31 | Astrazeneca Ab | Derivados de quinolina |
EP1994023A1 (en) * | 2006-03-02 | 2008-11-26 | AstraZeneca AB | Quinazoline derivatives |
EP2040711A2 (en) * | 2006-05-18 | 2009-04-01 | Amphora Discovery Corporation | 2-oxo-1,2-dihydroquinoline derivatives, compositions, and uses thereof as antiproliferative agents |
GB0619342D0 (en) * | 2006-09-30 | 2006-11-08 | Vernalis R&D Ltd | New chemical compounds |
US20100120717A1 (en) | 2006-10-09 | 2010-05-13 | Brown Jason W | Kinase inhibitors |
US20110033461A1 (en) * | 2008-03-12 | 2011-02-10 | Vladimir Ratushny | Combination Therapy for the Treatment of Cancer |
JP7117323B2 (ja) * | 2017-04-27 | 2022-08-12 | アストラゼネカ・アクチエボラーグ | フェノキシキナゾリン化合物及び癌の処置におけるそれらの使用 |
JP7128204B2 (ja) * | 2017-04-27 | 2022-08-30 | アストラゼネカ・アクチエボラーグ | C5-アニリノキナゾリン化合物及び癌の処置におけるそれらの使用 |
KR20190043842A (ko) | 2017-10-19 | 2019-04-29 | 건국대학교 산학협력단 | 피리미딘-2-아민 유도체, 이의 제조방법 및 이를 포함하는 항암제 |
CN110372666B (zh) * | 2018-04-13 | 2022-11-08 | 华东理工大学 | 喹唑啉类化合物作为egfr三突变抑制剂及其应用 |
JP2022520907A (ja) * | 2019-02-19 | 2022-04-01 | ザ・リージエンツ・オブ・ザ・ユニバーシテイー・オブ・カリフオルニア | Nurr1受容体調節因子 |
KR102061458B1 (ko) | 2019-08-14 | 2019-12-31 | 건국대학교 산학협력단 | 피리미딘-2-아민 유도체, 이의 제조방법 및 이를 포함하는 항암제 |
CN112939948B (zh) * | 2019-12-11 | 2022-05-17 | 苏州美诺医药科技有限公司 | 新型含喹唑啉类化合物及其中间体与应用 |
CN113200964B (zh) * | 2021-04-25 | 2022-07-05 | 南方医科大学南方医院 | 18f标记的egfr正电子显像剂及其制备方法与应用 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB9922171D0 (en) * | 1999-09-21 | 1999-11-17 | Zeneca Ltd | Chemical compounds |
ATE394102T1 (de) * | 2000-06-28 | 2008-05-15 | Astrazeneca Ab | Substituierte chinazolin-derivate und deren verwendung als aurora-2-kinase inhibitoren |
US7132427B2 (en) * | 2001-06-21 | 2006-11-07 | Ariad Pharmaceuticals, Inc. | Quinazolines and uses thereof |
IL162541A0 (en) * | 2001-12-24 | 2005-11-20 | Astrazeneca Ab | Substituted quinazoline derivatives as inhibitors of aurora kinases |
-
2004
- 2004-06-07 TW TW093116336A patent/TW200505452A/zh unknown
- 2004-06-14 JP JP2006516425A patent/JP2006527748A/ja active Pending
- 2004-06-14 EP EP04736769A patent/EP1644361A1/en not_active Withdrawn
- 2004-06-14 US US10/560,659 patent/US20060178382A1/en not_active Abandoned
- 2004-06-14 KR KR1020057024207A patent/KR20060011891A/ko not_active Application Discontinuation
- 2004-06-14 BR BRPI0411503-1A patent/BRPI0411503A/pt not_active Application Discontinuation
- 2004-06-14 CN CNA2004800231405A patent/CN1835945A/zh active Pending
- 2004-06-14 MX MXPA05013825A patent/MXPA05013825A/es unknown
- 2004-06-14 WO PCT/GB2004/002564 patent/WO2004113324A1/en active Application Filing
- 2004-06-14 CA CA002529250A patent/CA2529250A1/en not_active Abandoned
- 2004-06-14 AU AU2004249477A patent/AU2004249477A1/en not_active Abandoned
- 2004-06-17 AR ARP040102113A patent/AR045694A1/es unknown
- 2004-06-17 UY UY28366A patent/UY28366A1/es not_active Application Discontinuation
-
2005
- 2005-12-05 IL IL172375A patent/IL172375A0/en unknown
- 2005-12-12 NO NO20055891A patent/NO20055891L/no not_active Application Discontinuation
- 2005-12-15 ZA ZA200510257A patent/ZA200510257B/en unknown
Also Published As
Publication number | Publication date |
---|---|
ZA200510257B (en) | 2007-05-30 |
AU2004249477A1 (en) | 2004-12-29 |
JP2006527748A (ja) | 2006-12-07 |
US20060178382A1 (en) | 2006-08-10 |
WO2004113324A1 (en) | 2004-12-29 |
EP1644361A1 (en) | 2006-04-12 |
KR20060011891A (ko) | 2006-02-03 |
MXPA05013825A (es) | 2006-02-28 |
CA2529250A1 (en) | 2004-12-29 |
UY28366A1 (es) | 2005-01-31 |
BRPI0411503A (pt) | 2006-07-25 |
CN1835945A (zh) | 2006-09-20 |
TW200505452A (en) | 2005-02-16 |
AR045694A1 (es) | 2005-11-09 |
IL172375A0 (en) | 2009-02-11 |
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Legal Events
Date | Code | Title | Description |
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |