NO20042910L - Fremgangsmate for fremstilling av virusantigen i stor skala - Google Patents
Fremgangsmate for fremstilling av virusantigen i stor skalaInfo
- Publication number
- NO20042910L NO20042910L NO20042910A NO20042910A NO20042910L NO 20042910 L NO20042910 L NO 20042910L NO 20042910 A NO20042910 A NO 20042910A NO 20042910 A NO20042910 A NO 20042910A NO 20042910 L NO20042910 L NO 20042910L
- Authority
- NO
- Norway
- Prior art keywords
- production method
- large scale
- virus antigen
- antigen production
- scale virus
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N7/00—Viruses; Bacteriophages; Compositions thereof; Preparation or purification thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K2039/51—Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
- A61K2039/525—Virus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2760/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA ssRNA viruses negative-sense
- C12N2760/00011—Details
- C12N2760/16011—Orthomyxoviridae
- C12N2760/16111—Influenzavirus A, i.e. influenza A virus
- C12N2760/16151—Methods of production or purification of viral material
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
- Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
- Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Organic Chemistry (AREA)
- Zoology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Wood Science & Technology (AREA)
- Virology (AREA)
- Biotechnology (AREA)
- Microbiology (AREA)
- Biomedical Technology (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Immunology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Apparatus Associated With Microorganisms And Enzymes (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US10/006,881 US6951752B2 (en) | 2001-12-10 | 2001-12-10 | Method for large scale production of virus antigen |
PCT/EP2002/014011 WO2003054174A1 (en) | 2001-12-10 | 2002-12-10 | Method for large scale production of virus antigen |
Publications (1)
Publication Number | Publication Date |
---|---|
NO20042910L true NO20042910L (no) | 2004-07-09 |
Family
ID=21723079
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20042910A NO20042910L (no) | 2001-12-10 | 2004-07-09 | Fremgangsmate for fremstilling av virusantigen i stor skala |
Country Status (18)
Country | Link |
---|---|
US (2) | US6951752B2 (no) |
EP (3) | EP1453956B2 (no) |
JP (2) | JP4370511B2 (no) |
CN (2) | CN101100657B (no) |
AT (1) | ATE447010T2 (no) |
AU (1) | AU2002358662B2 (no) |
CA (1) | CA2469644C (no) |
DE (2) | DE122010000025I1 (no) |
DK (2) | DK1453956T3 (no) |
ES (2) | ES2488818T3 (no) |
FR (1) | FR10C0026I1 (no) |
HK (2) | HK1115609A1 (no) |
HU (1) | HU225791B1 (no) |
MX (1) | MXPA04005644A (no) |
NO (1) | NO20042910L (no) |
PL (1) | PL208232B1 (no) |
RU (1) | RU2314344C2 (no) |
WO (1) | WO2003054174A1 (no) |
Families Citing this family (61)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US7445924B2 (en) * | 2000-11-23 | 2008-11-04 | Bavarian Nordic A/S | Modified Vaccinia Ankara virus variant and cultivation method |
US6951752B2 (en) * | 2001-12-10 | 2005-10-04 | Bexter Healthcare S.A. | Method for large scale production of virus antigen |
EA006485B1 (ru) * | 2001-12-20 | 2005-12-29 | Бавариан Нордик А/С | Способ выделения и очистки поксвирусов из инфицированных клеток |
NZ538575A (en) | 2002-09-05 | 2007-03-30 | Bavarian Nordic As | Method for the amplification of a virus wherein primary avian cells are cultivated in a serum-free medium comprising growth factors and attachment factors |
CN101857851A (zh) * | 2002-12-23 | 2010-10-13 | 布里斯托尔-迈尔斯斯奎布公司 | 用于蛋白质生产的哺乳动物细胞培养方法 |
JP2007515172A (ja) * | 2003-12-23 | 2007-06-14 | シェーリング コーポレイション | 無血清培地懸濁培養において安定なa549細胞株を生成するための方法 |
ES2329607T3 (es) | 2004-02-23 | 2009-11-27 | Crucell Holland B.V. | Metodos de purificacion de virus. |
EP1739167B1 (en) * | 2004-04-19 | 2015-08-12 | DENKA SEIKEN Co., Ltd. | Method of producing virus |
RU2006145303A (ru) * | 2004-05-20 | 2008-06-27 | АйДи БАЙОМЕДИКАЛ КОРПОРЕЙШН (CA) | Способ получения противогриппозной вакцины |
US7344839B2 (en) * | 2004-12-23 | 2008-03-18 | Aurx, Inc. | Virus preparations and methods |
AU2005322353B2 (en) | 2004-12-23 | 2011-09-01 | Medimmune, Llc | Non-tumorigenic MDCK cell line for propagating viruses |
WO2007126810A2 (en) | 2006-03-31 | 2007-11-08 | Warf - Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses for vaccines |
CN103361319A (zh) | 2006-09-15 | 2013-10-23 | 米迪缪尼有限公司 | 支持病毒生长到高效价的mdck细胞系和采用该细胞系的生物反应器方法 |
JP5084214B2 (ja) * | 2006-09-29 | 2012-11-28 | 一般財団法人日本ポリオ研究所 | Ipvワクチン |
MX2009011899A (es) * | 2007-05-04 | 2010-03-30 | Baxter Int | Perfil de temperatura de dos pasos para la propagacion de virus. |
US9474798B2 (en) | 2007-06-18 | 2016-10-25 | Wisconsin Alumni Research Foundation | Influenza M2 protein mutant viruses as live influenza attenuated vaccines |
US20110014624A1 (en) * | 2008-03-12 | 2011-01-20 | Wyeth Llc | Methods For Identifying Cells Suitable For Large-Scale Production of Recombinant Proteins |
JP5689796B2 (ja) * | 2008-08-01 | 2015-03-25 | ガマ ワクチンズ ピーティワイ リミテッド | インフルエンザワクチン |
EP2334328A4 (en) | 2008-09-24 | 2012-08-29 | Medimmune Llc | METHOD FOR CLEANING VIRUSES |
CN103952376A (zh) | 2008-09-24 | 2014-07-30 | 米迪缪尼有限公司 | 培养细胞、增殖和纯化病毒的方法 |
CA2768997C (en) | 2009-07-31 | 2017-09-12 | Xcellerex, Inc. | High yield yellow fever virus strain with increased propagation in cells |
JP2013507990A (ja) | 2009-10-26 | 2013-03-07 | ダブリュエーアールエフ−ウィスコンシン アラムナイ リサーチ ファウンデーション | ベロ細胞において増強された複製を有する高力価の組換えインフルエンザウイルス |
BR112012015596B1 (pt) * | 2009-12-23 | 2021-06-01 | Sanofi Pasteur | Processo de cultura de células aderentes |
US10130697B2 (en) | 2010-03-23 | 2018-11-20 | Wisconsin Alumni Research Foundation (Warf) | Vaccines comprising mutant attenuated influenza viruses |
BR112012026095A2 (pt) | 2010-04-14 | 2015-09-15 | Emd Millipore Corp | métodos de produção de estoques de vírus de alta pureza e altos títulos e métodos de uso dos mesmos. |
WO2012048275A2 (en) | 2010-10-08 | 2012-04-12 | Caridianbct, Inc. | Configurable methods and systems of growing and harvesting cells in a hollow fiber bioreactor system |
CN101979517B (zh) * | 2010-10-15 | 2011-12-28 | 普莱柯生物工程股份有限公司 | 一种利用生物反应器大规模生产流感病毒的方法 |
EP2667891B1 (en) | 2011-01-27 | 2021-10-06 | Gamma Vaccines Pty Limited | Combination vaccines |
CN102492659A (zh) * | 2011-11-14 | 2012-06-13 | 成都康华生物制品有限公司 | 一种疫苗生产用甲肝病毒的生产方法 |
EP3022296B1 (en) | 2013-07-15 | 2022-12-28 | Wisconsin Alumni Research Foundation | High titer recombinant influenza viruses with enhanced replication in mdck or vero cells or eggs |
CN103387958B (zh) * | 2013-08-16 | 2016-04-06 | 北京科兴中维生物技术有限公司 | 人胚肺成纤维细胞sv-7在病毒培养中的应用 |
JP6612227B2 (ja) | 2013-11-16 | 2019-11-27 | テルモ ビーシーティー、インコーポレーテッド | バイオリアクターにおける細胞増殖 |
EP3122866B1 (en) | 2014-03-25 | 2019-11-20 | Terumo BCT, Inc. | Passive replacement of media |
WO2015196150A2 (en) | 2014-06-20 | 2015-12-23 | Wisconsin Alumni Research Foundation (Warf) | Mutations that confer genetic stability to additional genes in influenza viruses |
JP6830059B2 (ja) | 2014-09-26 | 2021-02-17 | テルモ ビーシーティー、インコーポレーテッド | スケジュール化された細胞フィーディング |
JP6288311B2 (ja) | 2015-01-26 | 2018-03-07 | 宇部興産株式会社 | 物質の産生方法 |
CA2969197C (en) | 2015-01-26 | 2020-08-18 | Ube Industries, Ltd. | Method, device and kit for mass cultivation of cells using polyimide porous membrane |
US10633422B2 (en) | 2015-06-01 | 2020-04-28 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication by inhibiting microRNA lec7C binding to influenza viral cRNA and mRNA |
WO2017004592A1 (en) | 2015-07-02 | 2017-01-05 | Terumo Bct, Inc. | Cell growth with mechanical stimuli |
US9890363B2 (en) | 2015-07-06 | 2018-02-13 | Wisconsin Alumni Research Foundation (Warf) | Influenza virus replication for vaccine development |
US11197925B2 (en) | 2016-02-19 | 2021-12-14 | Wisconsin Alumni Research Foundation (Warf) | Influenza B virus replication for vaccine development |
JP7034949B2 (ja) | 2016-05-25 | 2022-03-14 | テルモ ビーシーティー、インコーポレーテッド | 細胞の増殖 |
US11685883B2 (en) | 2016-06-07 | 2023-06-27 | Terumo Bct, Inc. | Methods and systems for coating a cell growth surface |
US11104874B2 (en) | 2016-06-07 | 2021-08-31 | Terumo Bct, Inc. | Coating a bioreactor |
EP3489342B1 (en) | 2016-07-25 | 2022-01-26 | UBE Industries, Ltd. | Siphon type cultivation method |
KR102307420B1 (ko) | 2016-07-25 | 2021-09-29 | 우베 고산 가부시키가이샤 | 세포 배양 모듈 |
CN110612344B (zh) | 2017-03-31 | 2023-09-12 | 泰尔茂比司特公司 | 细胞扩增 |
US11624046B2 (en) | 2017-03-31 | 2023-04-11 | Terumo Bct, Inc. | Cell expansion |
EP3740234A1 (en) * | 2018-01-18 | 2020-11-25 | Yisheng Biopharma (Singapore) Pte. Ltd. | Method for adapting influenza viruses to vero cells |
US11911457B2 (en) | 2018-02-07 | 2024-02-27 | Bharat Biotech International Limited | Process for enterovirus purification and inactivation and vaccine compositions obtained thereof |
EP3914295A2 (en) | 2019-01-23 | 2021-12-01 | Yoshihiro Kawaoka | Mutations that confer genetic stability to additional genes in influenza viruses |
KR102228267B1 (ko) * | 2019-01-25 | 2021-03-17 | 바이로큐어 주식회사 | Bhk-21 세포를 이용한 바이러스 생산방법 |
WO2020153619A1 (ko) * | 2019-01-25 | 2020-07-30 | 바이로큐어 주식회사 | Bhk-21 세포를 이용한 바이러스 생산방법 |
CN113874496A (zh) | 2019-02-08 | 2021-12-31 | 威斯康星校友研究基金会(Warf) | 人源化细胞系 |
US20220098555A1 (en) * | 2019-02-15 | 2022-03-31 | Ology Bioservices, Inc. | Method for virus production |
CN114929269A (zh) | 2019-05-01 | 2022-08-19 | 威斯康星校友研究基金会(Warf) | 用于疫苗开发的改进的流感病毒复制 |
TW202122572A (zh) | 2019-08-09 | 2021-06-16 | 日商宇部興產股份有限公司 | 胞外體的產生方法 |
TW202122569A (zh) | 2019-08-09 | 2021-06-16 | 日商宇部興產股份有限公司 | 應用小片多孔膜的細胞培養法 |
WO2021041624A2 (en) | 2019-08-27 | 2021-03-04 | Yoshihiro Kawaoka | Recombinant influenza viruses with stabilized ha for replication in eggs |
CN111850169B (zh) * | 2020-07-16 | 2022-09-27 | 华农(肇庆)生物产业技术研究院有限公司 | 一种计算AIV在MDCK-sus细胞中细胞单位均产毒量的方法 |
GB2619893A (en) | 2021-03-23 | 2023-12-20 | Terumo Bct Inc | Cell capture and expansion |
Family Cites Families (14)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4525349A (en) | 1981-12-29 | 1985-06-25 | Societe Anonyme Dite: Institut Merueux | Process for the large-scale production of a vaccine against poliomyelitis and the resulting vaccine |
AT393356B (de) | 1989-12-22 | 1991-10-10 | Immuno Ag | Verfahren zur herstellung von fsme-virus-antigen |
US5719051A (en) * | 1989-12-22 | 1998-02-17 | Immuno Aktiengesellschaft | Perfusion system and a method for the large scale production of virus or virus antigen |
FR2723740B1 (fr) | 1994-08-16 | 1996-11-08 | Pasteur Merieux Serums Vacc | Procede de preparation d'antigenes du virus grippal, antigenes obtenus et leurs applications |
US5824536A (en) * | 1994-08-23 | 1998-10-20 | St. Jude Children's Research Hospital | Influenza virus replicated in mammalian cell culture and vaccine production |
EP2290053A1 (en) | 1994-11-10 | 2011-03-02 | Baxter Healthcare S.A. | Method for producing Influenza virus in protein-free cell culture medium |
DE19612966B4 (de) * | 1996-04-01 | 2009-12-10 | Novartis Vaccines And Diagnostics Gmbh & Co. Kg | MDCK-Zellen und Verfahren zur Vermehrung von Influenzaviren |
GB2319413B (en) * | 1996-11-12 | 2001-06-06 | Lsi Logic Corp | Driver circuits |
US6168944B1 (en) * | 1997-01-31 | 2001-01-02 | Schering Corporation | Methods for cultivating cells and propagating viruses |
EP1731598A1 (en) * | 1997-01-31 | 2006-12-13 | Schering Corporation | Methods for cultivating cells and propagating viruses |
AT407255B (de) | 1997-06-20 | 2001-02-26 | Immuno Ag | Rekombinanter zellklon mit erhöhter stabilität in serum- und proteinfreiem medium und verfahren zur gewinnung des stabilen zellklons |
US5994134A (en) * | 1998-05-04 | 1999-11-30 | Canji, Inc. | Viral production process |
US6951752B2 (en) * | 2001-12-10 | 2005-10-04 | Bexter Healthcare S.A. | Method for large scale production of virus antigen |
US6855535B2 (en) * | 2001-12-10 | 2005-02-15 | Baxter Healthcare S.A. | Method of large scale production of Hepatitis A virus |
-
2001
- 2001-12-10 US US10/006,881 patent/US6951752B2/en not_active Expired - Lifetime
-
2002
- 2002-12-10 AU AU2002358662A patent/AU2002358662B2/en not_active Expired
- 2002-12-10 DK DK02792957T patent/DK1453956T3/da active
- 2002-12-10 PL PL373487A patent/PL208232B1/pl unknown
- 2002-12-10 RU RU2004121178/13A patent/RU2314344C2/ru not_active IP Right Cessation
- 2002-12-10 CN CN2007101271424A patent/CN101100657B/zh not_active Expired - Lifetime
- 2002-12-10 CN CNB028279778A patent/CN100335619C/zh not_active Expired - Lifetime
- 2002-12-10 DE DE122010000025C patent/DE122010000025I1/de active Pending
- 2002-12-10 JP JP2003554878A patent/JP4370511B2/ja not_active Expired - Lifetime
- 2002-12-10 CA CA2469644A patent/CA2469644C/en not_active Expired - Lifetime
- 2002-12-10 DK DK10011842.1T patent/DK2330189T3/da active
- 2002-12-10 EP EP02792957.9A patent/EP1453956B2/en not_active Expired - Lifetime
- 2002-12-10 ES ES10011842.1T patent/ES2488818T3/es not_active Expired - Lifetime
- 2002-12-10 ES ES02792957.9T patent/ES2335395T5/es not_active Expired - Lifetime
- 2002-12-10 HU HU0402415A patent/HU225791B1/hu not_active IP Right Cessation
- 2002-12-10 DE DE60234211T patent/DE60234211D1/de not_active Expired - Lifetime
- 2002-12-10 MX MXPA04005644A patent/MXPA04005644A/es active IP Right Grant
- 2002-12-10 AT AT02792957T patent/ATE447010T2/de active
- 2002-12-10 EP EP07021348A patent/EP1894998A1/en not_active Withdrawn
- 2002-12-10 WO PCT/EP2002/014011 patent/WO2003054174A1/en active Application Filing
- 2002-12-10 EP EP10011842.1A patent/EP2330189B1/en not_active Expired - Lifetime
-
2004
- 2004-07-09 NO NO20042910A patent/NO20042910L/no not_active Application Discontinuation
-
2005
- 2005-03-17 US US11/084,485 patent/US7524676B2/en not_active Expired - Lifetime
-
2008
- 2008-06-02 HK HK08106127.5A patent/HK1115609A1/xx not_active IP Right Cessation
-
2009
- 2009-07-02 JP JP2009157882A patent/JP5021000B2/ja not_active Expired - Lifetime
-
2010
- 2010-04-16 FR FR10C0026C patent/FR10C0026I1/fr active Active
-
2011
- 2011-12-07 HK HK11113237.3A patent/HK1158691A1/xx not_active IP Right Cessation
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |