NO20041075L - Ny 1, 2, 4-triazolforbindelse - Google Patents
Ny 1, 2, 4-triazolforbindelseInfo
- Publication number
- NO20041075L NO20041075L NO20041075A NO20041075A NO20041075L NO 20041075 L NO20041075 L NO 20041075L NO 20041075 A NO20041075 A NO 20041075A NO 20041075 A NO20041075 A NO 20041075A NO 20041075 L NO20041075 L NO 20041075L
- Authority
- NO
- Norway
- Prior art keywords
- new
- triazole compound
- triazole
- compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/06—Antigout agents, e.g. antihyperuricemic or uricosuric agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/06—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2
- C07D311/08—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring
- C07D311/16—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 2 not hydrogenated in the hetero ring substituted in position 7
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP2002017825 | 2002-01-28 | ||
| PCT/JP2002/012662 WO2003064410A1 (fr) | 2002-01-28 | 2002-12-03 | Nouveau compose 1,2,4-triazole |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| NO20041075L true NO20041075L (no) | 2004-03-15 |
| NO326941B1 NO326941B1 (no) | 2009-03-16 |
Family
ID=27653386
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO20041075A NO326941B1 (no) | 2002-01-28 | 2004-03-15 | 1,2,4-triazolforbindelse, medikament som omfatter forbindelsen, og anvendelse av forbindelsen for fremstilling av farmasoytisk sammensetning mot sykdom |
Country Status (22)
| Country | Link |
|---|---|
| US (1) | US7074816B2 (no) |
| EP (1) | EP1471065B1 (no) |
| JP (1) | JP3600832B2 (no) |
| CN (1) | CN1561340B (no) |
| AR (1) | AR042602A1 (no) |
| AT (1) | ATE387438T1 (no) |
| AU (1) | AU2002349754B2 (no) |
| BR (1) | BRPI0212775B8 (no) |
| CA (1) | CA2462132C (no) |
| DE (1) | DE60225341T2 (no) |
| DK (1) | DK1471065T3 (no) |
| ES (1) | ES2300486T3 (no) |
| HK (1) | HK1067132A1 (no) |
| MX (1) | MXPA04004037A (no) |
| NO (1) | NO326941B1 (no) |
| NZ (1) | NZ531673A (no) |
| PL (1) | PL208260B1 (no) |
| PT (1) | PT1471065E (no) |
| RU (1) | RU2293733C2 (no) |
| TW (1) | TWI257926B (no) |
| WO (1) | WO2003064410A1 (no) |
| ZA (1) | ZA200401777B (no) |
Families Citing this family (48)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR20060037373A (ko) * | 2003-07-24 | 2006-05-03 | 가부시키가이샤 후지야쿠힝 | 1,2,4-트리아졸 화합물의 제조 방법 및 그 중간체 |
| US20060189811A1 (en) * | 2004-07-23 | 2006-08-24 | Fujiyakuhin Co., Ltd. | Process for producing 1,2,4-triazole compound and intermediate therefor |
| EP1883405A4 (en) | 2005-05-09 | 2010-01-27 | Takeda Pharmaceuticals North A | METHODS OF TREATING NEPHROLITHIASIS |
| WO2007019153A2 (en) * | 2005-08-03 | 2007-02-15 | Tap Pharmaceutical Products, Inc. | Methods for treating hypertension |
| WO2007043400A1 (ja) * | 2005-10-07 | 2007-04-19 | Kissei Pharmaceutical Co., Ltd. | 含窒素芳香族複素環化合物およびそれを含有する医薬組成物 |
| CA2655895A1 (en) * | 2006-06-22 | 2007-12-27 | Nippon Chemiphar Co., Ltd. | Agent for overcoming resistance to anti-cancer agent |
| EP2050467B1 (en) * | 2006-07-19 | 2014-09-10 | Nippon Medical School Foundation | Therapeutic agent for amyotrophic lateral sclerosis |
| US20090124623A1 (en) * | 2006-11-13 | 2009-05-14 | Christopher Lademacher | Methods for preserving and/or increasing renal function using xanthine oxidoreductase inhibitors |
| EP2101761A4 (en) * | 2006-11-13 | 2010-01-27 | Takeda Pharmaceuticals North A | METHODS FOR PRESERVING RENAL FUNCTION USING XANTHINE OXYDOREDUCTASE INHIBITORS |
| WO2008089296A1 (en) * | 2007-01-19 | 2008-07-24 | Takeda Pharmaceuticals North America | Methods for preventing or reducing the number of gout flares using xanthine oxidoreductase inhibitors and anti-inflammatory agents |
| JO2784B1 (en) * | 2007-10-18 | 2014-03-15 | شركة جانسين فارماسوتيكا ان. في | 5,3,1 - Triazole substitute derivative |
| CN101918377A (zh) | 2007-11-27 | 2010-12-15 | 亚德生化公司 | 新颖化合物和组合物以及使用方法 |
| EP2165705A1 (en) | 2008-09-18 | 2010-03-24 | Centre National de la Recherche Scientifique (CNRS) | Use of a compound capable of reducing the uric acid level for the prevention and/or the treatment of lung inflammation and fibrosis |
| US20100311756A1 (en) * | 2009-01-22 | 2010-12-09 | Takeda Pharmaceuticals North America, Inc. | Methods for delaying the progression of at least one of cardiac hypertrophy, cardiac remodeling or left ventricular function or the onset of heart failure in subjects in need of treatment thereof |
| JP5978216B2 (ja) | 2010-09-10 | 2016-08-24 | タケダ ファーマシューティカルズ ユー．エス．エー． インコーポレイティド | テオフィリンとフェブキソスタットの併用療法のための方法 |
| JP5862897B2 (ja) * | 2010-11-01 | 2016-02-16 | 株式会社三和化学研究所 | 腎機能障害の予防又は治療に用いる医薬 |
| AU2011342039B2 (en) | 2010-12-17 | 2015-06-11 | Mitsubishi Tanabe Pharma Corporation | Continuous arycyclic compound |
| WO2012118485A1 (en) | 2011-03-01 | 2012-09-07 | Empire Technology Development Llc | Temperature controlled variable reflectivity coatings |
| RU2476428C1 (ru) * | 2011-09-01 | 2013-02-27 | Государственное образовательное учреждение высшего профессионального образования "Южно-Российский государственный технический университет (Новочеркасский политехнический институт)" | Способ получения дигидрохлорида 5-амино-3-аминометил-1,2,4-триазола |
| US9546155B2 (en) | 2012-06-15 | 2017-01-17 | Mitsubishi Tanabe Pharma Corporation | Aromatic heterocyclic compound |
| US9199970B2 (en) * | 2012-07-25 | 2015-12-01 | Fujiyakuhin Co., Ltd. | 4-[5-(pyridin-4-yl)-1H-1,2,4-triazol-3-yl]pyridine-2-carbonitrile crystalline polymorph and production method therefor |
| RU2644766C2 (ru) | 2012-07-25 | 2018-02-14 | Фудзиякухин Ко., Лтд. | Способ получения 4-[5-(пиридин-4-ил)-1н-1,2,4-триазол-3-ил]пиридин-2-карбонитрила и его промежуточное соединение |
| CN103724329B (zh) * | 2013-12-23 | 2015-02-18 | 济南百诺医药科技开发有限公司 | 4-[5-(吡啶-4-基)-1h-[1,2,4]三唑-3-基]吡啶-2-甲腈的制备方法 |
| CN104042577B (zh) * | 2014-06-13 | 2016-08-24 | 安徽省逸欣铭医药科技有限公司 | 一种稳定的托匹司他片及其制备方法 |
| CN105315260A (zh) * | 2014-07-29 | 2016-02-10 | 北京海步医药科技股份有限公司 | 一种托布司他一水合物晶型及其制备方法 |
| CN105348264B (zh) * | 2014-08-18 | 2018-01-16 | 上海医药工业研究院 | 一种托吡司他的合成方法 |
| CN105367490B (zh) * | 2014-08-18 | 2019-01-04 | 上海医药工业研究院 | 合成托吡司他的新中间体及其制备方法 |
| CN104151297B (zh) * | 2014-08-27 | 2016-03-16 | 王庆本 | 4-[5-(吡啶-4-基)-1h-[1，2，4]三唑-3-基]吡啶-2-甲腈的制备方法 |
| WO2016133069A1 (ja) * | 2015-02-17 | 2016-08-25 | 株式会社 三和化学研究所 | 心不全の予防又は治療のための医薬 |
| WO2016136727A1 (ja) | 2015-02-24 | 2016-09-01 | 国立大学法人鳥取大学 | 認知症の予防及び／又は治療のための医薬 |
| CN107531677A (zh) * | 2015-02-25 | 2018-01-02 | 法尔玛赞公司 | 用于制备托匹司他及其中间体的方法 |
| CN105693699B (zh) * | 2015-03-30 | 2019-06-18 | 苏州晶云药物科技股份有限公司 | 托吡司他的晶型及其制备方法 |
| CN104910068B (zh) * | 2015-04-24 | 2017-07-14 | 南京医科大学 | 一种2‑氰基异烟酸酰肼1.5对甲苯磺酸盐的合成方法 |
| CN106279111A (zh) * | 2015-05-12 | 2017-01-04 | 北京济美堂医药研究有限公司 | 一种精制托吡司他的新方法 |
| CN104961730B (zh) * | 2015-06-18 | 2017-05-17 | 山东金城医药化工股份有限公司 | 托吡司他新晶型及其制备方法 |
| CN105130958B (zh) * | 2015-08-31 | 2017-10-31 | 济南康和医药科技有限公司 | 5‑(2‑氰基4‑吡啶基)‑3‑(4‑吡啶基)‑1,2,4‑三唑的制备工艺 |
| CN105294656A (zh) * | 2015-10-10 | 2016-02-03 | 大道隆达（北京）医药科技发展有限公司 | 一种托匹司他的制备工艺和方法 |
| CN106336399A (zh) * | 2015-11-03 | 2017-01-18 | 江苏悦兴药业有限公司 | 托匹司他工艺杂质的制备方法 |
| CN105294584A (zh) * | 2015-11-30 | 2016-02-03 | 中国医科大学 | 1-取代苯基-1h-1,2,3-三唑类化合物、制备方法及其用途 |
| CN105399732A (zh) * | 2015-12-07 | 2016-03-16 | 青岛正大海尔制药有限公司 | 一种托匹司他的制备方法 |
| CN106008465A (zh) * | 2016-03-16 | 2016-10-12 | 江苏悦兴药业有限公司 | 一种托匹司他杂质的合成方法 |
| CN108250183A (zh) * | 2016-12-29 | 2018-07-06 | 北京诚济制药有限公司 | 一种高纯度的托匹司他的制备方法 |
| CN109721586B (zh) * | 2017-10-27 | 2021-03-02 | 中国医科大学 | 一种5-苄基-3-吡啶基-1h-1,2,4-三唑类化合物及其制备方法和用途 |
| CN107652271B (zh) * | 2017-11-06 | 2020-06-16 | 上海中拓医药科技有限公司 | 一种托匹司他晶型i的制备方法 |
| CN108017619B (zh) * | 2017-12-06 | 2020-08-11 | 成都惟邦药业有限公司 | 一种托匹司他杂质及其制备方法 |
| CN113354616B (zh) * | 2020-03-05 | 2024-03-26 | 中国医学科学院药物研究所 | 二芳基-1,2,4-三唑类化合物及其制法和药物用途 |
| CN113666909A (zh) * | 2020-05-14 | 2021-11-19 | 鲁南制药集团股份有限公司 | 一种托匹司他的制备方法 |
| CN114773262A (zh) * | 2022-05-19 | 2022-07-22 | 兄弟科技股份有限公司 | 2-氰基-4-吡啶羧酸甲酯的合成方法 |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL7112373A (no) * | 1970-09-25 | 1972-03-28 | ||
| US3882134A (en) * | 1973-05-21 | 1975-05-06 | Merck & Co Inc | 1-Substituted-3,5-dipyridyl-1,2,4-triazoles |
| US3984558A (en) * | 1973-05-21 | 1976-10-05 | Merck & Co., Inc. | 1,3,5-Trisubstituted-1,2,4-triazole compounds used as bronchodilators |
| US3928361A (en) * | 1973-05-21 | 1975-12-23 | Merck & Co Inc | 1-(Sulfamoylphenylalkyl)-3,5-dipyridyl-1,2,4 triazoles |
| US3947577A (en) * | 1973-05-21 | 1976-03-30 | Merck & Co., Inc. | Anti-hyperuricemia composition |
| US3963731A (en) * | 1973-05-21 | 1976-06-15 | Merck & Co., Inc. | Pyridyl containing 1-benzenesulfonyl triazoles |
| US4104393A (en) * | 1976-04-02 | 1978-08-01 | Merck & Co., Inc. | 1,3,5-Trisubstituted-1,2,4-triazole compounds |
| DE69131206T2 (de) * | 1991-12-05 | 2000-01-05 | Wallac Oy | Lumineszierende lanthanidenchelate |
| BR9915534B1 (pt) * | 1998-10-23 | 2011-04-19 | 1-piridil substituìdo)-1,2,4-triazóis inseticidas. | |
| PL369598A1 (en) * | 2001-02-21 | 2005-05-02 | Nps Pharmaceuticals, Inc. | Heteropolycyclic compounds and their use as metabotropic glutamate receptor antagonists |
-
2002
- 2002-12-03 PL PL368672A patent/PL208260B1/pl unknown
- 2002-12-03 DE DE60225341T patent/DE60225341T2/de not_active Expired - Lifetime
- 2002-12-03 RU RU2004106554/04A patent/RU2293733C2/ru active
- 2002-12-03 US US10/495,322 patent/US7074816B2/en not_active Expired - Lifetime
- 2002-12-03 WO PCT/JP2002/012662 patent/WO2003064410A1/ja active IP Right Grant
- 2002-12-03 CN CN028192761A patent/CN1561340B/zh not_active Expired - Lifetime
- 2002-12-03 NZ NZ531673A patent/NZ531673A/en not_active IP Right Cessation
- 2002-12-03 CA CA2462132A patent/CA2462132C/en not_active Expired - Lifetime
- 2002-12-03 BR BRPI0212775A patent/BRPI0212775B8/pt not_active IP Right Cessation
- 2002-12-03 AT AT02781876T patent/ATE387438T1/de active
- 2002-12-03 AU AU2002349754A patent/AU2002349754B2/en not_active Ceased
- 2002-12-03 EP EP02781876A patent/EP1471065B1/en not_active Expired - Lifetime
- 2002-12-03 MX MXPA04004037A patent/MXPA04004037A/es active IP Right Grant
- 2002-12-03 JP JP2003564033A patent/JP3600832B2/ja not_active Expired - Lifetime
- 2002-12-03 PT PT02781876T patent/PT1471065E/pt unknown
- 2002-12-03 ES ES02781876T patent/ES2300486T3/es not_active Expired - Lifetime
- 2002-12-03 DK DK02781876T patent/DK1471065T3/da active
- 2002-12-09 TW TW091135529A patent/TWI257926B/zh not_active IP Right Cessation
- 2002-12-17 AR ARP020104915A patent/AR042602A1/es not_active Application Discontinuation
-
2004
- 2004-03-04 ZA ZA2004/01777A patent/ZA200401777B/en unknown
- 2004-03-15 NO NO20041075A patent/NO326941B1/no not_active IP Right Cessation
-
2005
- 2005-01-25 HK HK05100651.5A patent/HK1067132A1/xx not_active IP Right Cessation
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| MM1K | Lapsed by not paying the annual fees |