NO20032111L - Nye medikamentblandinger basert pa tiotropium-salter og pa salmeterol-salter - Google Patents
Nye medikamentblandinger basert pa tiotropium-salter og pa salmeterol-salterInfo
- Publication number
- NO20032111L NO20032111L NO20032111A NO20032111A NO20032111L NO 20032111 L NO20032111 L NO 20032111L NO 20032111 A NO20032111 A NO 20032111A NO 20032111 A NO20032111 A NO 20032111A NO 20032111 L NO20032111 L NO 20032111L
- Authority
- NO
- Norway
- Prior art keywords
- salts
- salmeterol
- new drug
- tiotropium
- mixtures based
- Prior art date
Links
- GIIZNNXWQWCKIB-UHFFFAOYSA-N Serevent Chemical class C1=C(O)C(CO)=CC(C(O)CNCCCCCCOCCCCC=2C=CC=CC=2)=C1 GIIZNNXWQWCKIB-UHFFFAOYSA-N 0.000 title abstract 2
- 239000000203 mixture Substances 0.000 title abstract 2
- LERNTVKEWCAPOY-DZZGSBJMSA-N tiotropium Chemical class O([C@H]1C[C@@H]2[N+]([C@H](C1)[C@@H]1[C@H]2O1)(C)C)C(=O)C(O)(C=1SC=CC=1)C1=CC=CS1 LERNTVKEWCAPOY-DZZGSBJMSA-N 0.000 title abstract 2
- 239000002547 new drug Substances 0.000 title 1
- 229940079593 drug Drugs 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 208000023504 respiratory system disease Diseases 0.000 abstract 1
- 238000002560 therapeutic procedure Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/46—8-Azabicyclo [3.2.1] octane; Derivatives thereof, e.g. atropine, cocaine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/135—Amines having aromatic rings, e.g. ketamine, nortriptyline
- A61K31/137—Arylalkylamines, e.g. amphetamine, epinephrine, salbutamol, ephedrine or methadone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/439—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom the ring forming part of a bridged ring system, e.g. quinuclidine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/007—Pulmonary tract; Aromatherapy
- A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
- A61K9/008—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy comprising drug dissolved or suspended in liquid propellant for inhalation via a pressurized metered dose inhaler [MDI]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pulmonology (AREA)
- Epidemiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Otolaryngology (AREA)
- Emergency Medicine (AREA)
- Immunology (AREA)
- Dispersion Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Abstract
Den foreliggende oppfinnelse vedrører nye legemiddelblandinger på basis av Tiotropiumsalter og salter av Salmeterol, en fremgangsmåte for deres fremstilling samt deres anvendelse ved terapi av luftveissykdommer.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE10056104A DE10056104A1 (de) | 2000-11-13 | 2000-11-13 | Neue Arzneimittelkompositionen auf der Basis von Tiotropiumsalzen und Salzen des Salmeterols |
PCT/EP2001/012962 WO2002038154A1 (de) | 2000-11-13 | 2001-11-09 | Neue arzneimittelkompositionen auf der basis von tiotropiumsalzen und salzen des salmeterols |
Publications (2)
Publication Number | Publication Date |
---|---|
NO20032111D0 NO20032111D0 (no) | 2003-05-12 |
NO20032111L true NO20032111L (no) | 2003-07-08 |
Family
ID=7663071
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO20032111A NO20032111L (no) | 2000-11-13 | 2003-05-12 | Nye medikamentblandinger basert pa tiotropium-salter og pa salmeterol-salter |
Country Status (32)
Country | Link |
---|---|
EP (3) | EP1514546B1 (no) |
JP (2) | JP4282322B2 (no) |
KR (2) | KR100886094B1 (no) |
CN (1) | CN1678318A (no) |
AT (2) | ATE291428T1 (no) |
AU (3) | AU2791002A (no) |
BG (1) | BG107781A (no) |
BR (1) | BR0115226A (no) |
CA (1) | CA2429012A1 (no) |
CY (1) | CY1106774T1 (no) |
CZ (1) | CZ20031444A3 (no) |
DE (3) | DE10056104A1 (no) |
DK (2) | DK1335728T3 (no) |
EA (1) | EA007904B1 (no) |
EC (1) | ECSP034571A (no) |
EE (1) | EE200300228A (no) |
ES (2) | ES2240549T3 (no) |
HR (1) | HRP20030378A2 (no) |
HU (1) | HUP0301447A3 (no) |
IL (2) | IL155718A0 (no) |
MX (1) | MXPA03004164A (no) |
NO (1) | NO20032111L (no) |
NZ (1) | NZ526400A (no) |
PL (1) | PL205330B1 (no) |
PT (2) | PT1335728E (no) |
RS (2) | RS20090105A (no) |
SG (1) | SG167657A1 (no) |
SI (2) | SI1335728T1 (no) |
SK (2) | SK286950B6 (no) |
UA (1) | UA74853C2 (no) |
WO (1) | WO2002038154A1 (no) |
ZA (1) | ZA200302921B (no) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
US7214687B2 (en) | 1999-07-14 | 2007-05-08 | Almirall Ag | Quinuclidine derivatives and medicinal compositions containing the same |
EP1523976A3 (en) * | 1999-11-23 | 2005-06-22 | Glaxo Group Limited | Pharmaceutical formulations of salmeterol |
WO2003024452A1 (de) * | 2001-09-14 | 2003-03-27 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Neue arzneimittel zur inhalation |
US7244415B2 (en) | 2002-03-28 | 2007-07-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | HFA suspension formulations of an anhydrate |
DE10214263A1 (de) * | 2002-03-28 | 2003-10-16 | Boehringer Ingelheim Pharma | HFA-Suspensionsformulierungen enthaltend ein Anticholinergikum |
US7311894B2 (en) | 2002-03-28 | 2007-12-25 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | HFA suspension formulations containing an anticholinergic |
US7250426B2 (en) | 2002-11-29 | 2007-07-31 | Boehringer Ingelheim Pharma Gmbh & Co Kg | Tiotropium-containing pharmaceutical combination for inhalation |
DE10256080A1 (de) * | 2002-11-29 | 2004-06-17 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Tiotropiumhaltige Arzneimittelkombination für die Inhalation |
CN1726038A (zh) * | 2002-12-16 | 2006-01-25 | 贝林格尔英格海姆法玛两合公司 | 含有噻托铵的hfc溶液剂 |
DE10351663A1 (de) * | 2002-12-20 | 2004-07-01 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Pulverförmige Arzneimittel enthaltend ein Tiotropiumsalz und Salmeterolxinafoat |
DE10345065A1 (de) * | 2003-09-26 | 2005-04-14 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Aerosolformulierung für die Inhalation enthaltend ein Anticholinergikum |
SG149876A1 (en) * | 2003-11-03 | 2009-02-27 | Boehringer Ingelheim Int | Novel tiotropium salts, methods for the production thereof, and pharmaceutical formulations containing the same |
SG137859A1 (en) * | 2003-11-03 | 2007-12-28 | Boehringer Ingelheim Int | Method for producing tiotropium salts, tiotropium salts and pharmaceutical formulations, containing the same |
ES2257152B1 (es) * | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
ATE474601T1 (de) * | 2004-05-31 | 2010-08-15 | Almirall Sa | Kombinationen mit antimuskarin-wirkstoffen und pde4-hemmern |
CN101166738B (zh) | 2005-05-02 | 2011-06-01 | 贝林格尔·英格海姆国际有限公司 | 噻托溴铵的新晶型 |
WO2007017437A1 (en) * | 2005-08-06 | 2007-02-15 | Boehringer Ingelheim International Gmbh | Method for the treatment of dyspnea comprising combined administration of tiotropium salts and salts of salmeterol |
ES2298049B1 (es) | 2006-07-21 | 2009-10-20 | Laboratorios Almirall S.A. | Procedimiento para fabricar bromuro de 3(r)-(2-hidroxi-2,2-ditien-2-ilacetoxi)-1-(3-fenoxipropil)-1-azoniabiciclo (2.2.2) octano. |
EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
US20120220557A1 (en) * | 2011-02-17 | 2012-08-30 | Chiesi Farmaceutici S.P.A. | Liquid propellant-free formulation comprising an antimuscarinic drug |
EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
JP6335798B2 (ja) * | 2012-02-28 | 2018-05-30 | ベーリンガー インゲルハイム インターナショナル ゲゼルシャフト ミット ベシュレンクテル ハフツング | 新規噴射剤含有チオトロピウム製剤 |
WO2015065222A1 (ru) * | 2013-10-28 | 2015-05-07 | Шолекс Девелопмент Гмбх | Фармацевтический ингаляционный препарат для лечения бронхиальной астмы и хронической обструктивной болезни легких, содержащий в качестве активного вещества микронизированный тиотропия бромид, и способ его получения |
TW201835041A (zh) | 2017-02-17 | 2018-10-01 | 印度商托仁特生技有限公司 | 具β-腎上腺素促效劑及抗蕈毒活性化合物 |
WO2019142214A1 (en) * | 2018-01-19 | 2019-07-25 | Cipla Limited | Pharmaceutical composition comprising tiotropium for inhalation |
CN116196298A (zh) * | 2018-07-26 | 2023-06-02 | 四川海思科制药有限公司 | 一种含格隆铵盐的气雾剂药物组合物及其制备方法与应用 |
WO2020019952A1 (zh) * | 2018-07-26 | 2020-01-30 | 四川海思科制药有限公司 | 一种含格隆铵盐及茚达特罗盐的气雾剂药物组合物及其制备方法与应用 |
US11642372B2 (en) | 2020-05-01 | 2023-05-09 | Tygrus, LLC | Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses |
US11826382B2 (en) | 2020-05-01 | 2023-11-28 | Tygrus, LLC | Therapeutic material with low pH and low toxicity active against at least one pathogen for addressing patients with respiratory illnesses |
WO2022119661A1 (en) * | 2020-12-04 | 2022-06-09 | Tygrus, LLC | THERAPEUTIC MATERIAL WITH LOW pH AND LOW TOXICITY ACTIVE AGAINST AT LEAST ONE PATHOGEN FOR ADDRESSING PATIENTS WITH RESPIRATORY ILLNESSES |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE59911149D1 (de) * | 1998-07-24 | 2004-12-30 | Jago Res Ag Muttenz | Medizinische aerosolformulierungen |
DE19835346A1 (de) * | 1998-08-05 | 2000-02-10 | Boehringer Ingelheim Pharma | Zweiteilige Kapsel zur Aufnahme von pharmazeutischen Zubereitungen für Pulverinhalatoren |
DE19847970A1 (de) * | 1998-10-17 | 2000-04-20 | Boehringer Ingelheim Pharma | Lagerfähige Wirkstoff-Formulierung |
DE19847971A1 (de) * | 1998-10-17 | 1999-09-02 | Schiering | Verfahren und Einrichtung zur Verhinderung von Filterbränden (Staubfilter) |
DE19921693A1 (de) * | 1999-05-12 | 2000-11-16 | Boehringer Ingelheim Pharma | Neuartige Arzneimittelkompositionen auf der Basis von anticholinergisch wirksamen Verbindungen und ß-Mimetika |
DE19961300A1 (de) * | 1999-12-18 | 2001-06-21 | Asta Medica Ag | Vorratssystem für Arzneimittel in Pulverform und damit ausgestatteter Inhalator |
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2000
- 2000-11-13 DE DE10056104A patent/DE10056104A1/de not_active Withdrawn
-
2001
- 2001-09-11 UA UA2003065486A patent/UA74853C2/uk unknown
- 2001-11-09 CA CA002429012A patent/CA2429012A1/en not_active Abandoned
- 2001-11-09 SK SK50015-2009A patent/SK286950B6/sk not_active IP Right Cessation
- 2001-11-09 SK SK741-2003A patent/SK286939B6/sk not_active IP Right Cessation
- 2001-11-09 PL PL365989A patent/PL205330B1/pl not_active IP Right Cessation
- 2001-11-09 SI SI200130347T patent/SI1335728T1/xx unknown
- 2001-11-09 JP JP2002540737A patent/JP4282322B2/ja not_active Expired - Lifetime
- 2001-11-09 SI SI200130751T patent/SI1514546T1/sl unknown
- 2001-11-09 EA EA200300503A patent/EA007904B1/ru not_active IP Right Cessation
- 2001-11-09 AU AU2791002A patent/AU2791002A/xx active Pending
- 2001-11-09 BR BR0115226-2A patent/BR0115226A/pt active Pending
- 2001-11-09 RS RSP-2009/0105A patent/RS20090105A/sr unknown
- 2001-11-09 CZ CZ20031444A patent/CZ20031444A3/cs unknown
- 2001-11-09 EE EEP200300228A patent/EE200300228A/xx unknown
- 2001-11-09 CN CNA018187773A patent/CN1678318A/zh active Pending
- 2001-11-09 EP EP04028508A patent/EP1514546B1/de not_active Expired - Lifetime
- 2001-11-09 AT AT01989446T patent/ATE291428T1/de active
- 2001-11-09 AT AT04028508T patent/ATE362761T1/de active
- 2001-11-09 HU HU0301447A patent/HUP0301447A3/hu unknown
- 2001-11-09 ES ES01989446T patent/ES2240549T3/es not_active Expired - Lifetime
- 2001-11-09 DK DK01989446T patent/DK1335728T3/da active
- 2001-11-09 EP EP01989446A patent/EP1335728B1/de not_active Expired - Lifetime
- 2001-11-09 PT PT01989446T patent/PT1335728E/pt unknown
- 2001-11-09 KR KR1020037006434A patent/KR100886094B1/ko not_active IP Right Cessation
- 2001-11-09 AU AU2002227910A patent/AU2002227910B2/en not_active Ceased
- 2001-11-09 NZ NZ526400A patent/NZ526400A/en unknown
- 2001-11-09 MX MXPA03004164A patent/MXPA03004164A/es active IP Right Grant
- 2001-11-09 RS YUP-355/03A patent/RS50286B/sr unknown
- 2001-11-09 DE DE50105729T patent/DE50105729D1/de not_active Expired - Lifetime
- 2001-11-09 PT PT04028508T patent/PT1514546E/pt unknown
- 2001-11-09 EP EP07104722A patent/EP1808174A1/de not_active Withdrawn
- 2001-11-09 KR KR1020087020177A patent/KR100940752B1/ko not_active IP Right Cessation
- 2001-11-09 DK DK04028508T patent/DK1514546T3/da active
- 2001-11-09 SG SG200505149-5A patent/SG167657A1/en unknown
- 2001-11-09 DE DE50112535T patent/DE50112535D1/de not_active Expired - Lifetime
- 2001-11-09 WO PCT/EP2001/012962 patent/WO2002038154A1/de active Application Filing
- 2001-11-09 ES ES04028508T patent/ES2287629T3/es not_active Expired - Lifetime
- 2001-11-09 IL IL15571801A patent/IL155718A0/xx unknown
-
2003
- 2003-04-14 ZA ZA200302921A patent/ZA200302921B/en unknown
- 2003-04-28 EC EC2003004571A patent/ECSP034571A/es unknown
- 2003-05-01 IL IL155718A patent/IL155718A/en not_active IP Right Cessation
- 2003-05-08 BG BG107781A patent/BG107781A/bg active Pending
- 2003-05-12 NO NO20032111A patent/NO20032111L/no not_active Application Discontinuation
- 2003-05-12 HR HR20030378A patent/HRP20030378A2/hr not_active Application Discontinuation
-
2004
- 2004-12-08 JP JP2004355226A patent/JP4282594B2/ja not_active Expired - Lifetime
-
2007
- 2007-05-22 AU AU2007202303A patent/AU2007202303B2/en not_active Ceased
- 2007-07-30 CY CY20071101011T patent/CY1106774T1/el unknown
Also Published As
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FC2A | Withdrawal, rejection or dismissal of laid open patent application |