NO179434C - Fremgangsmåte for fremstilling av et farmasöytisk preparat, og anvendelse av en vannopplöselig monoester som et solubiliserende middel - Google Patents

Fremgangsmåte for fremstilling av et farmasöytisk preparat, og anvendelse av en vannopplöselig monoester som et solubiliserende middel

Info

Publication number
NO179434C
NO179434C NO884052A NO884052A NO179434C NO 179434 C NO179434 C NO 179434C NO 884052 A NO884052 A NO 884052A NO 884052 A NO884052 A NO 884052A NO 179434 C NO179434 C NO 179434C
Authority
NO
Norway
Prior art keywords
preparing
water
pharmaceutical composition
solubilizing agent
soluble monoester
Prior art date
Application number
NO884052A
Other languages
English (en)
Norwegian (no)
Other versions
NO179434B (no
NO884052D0 (no
NO884052L (no
Inventor
Lorenz Hahn
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO884052D0 publication Critical patent/NO884052D0/no
Publication of NO884052L publication Critical patent/NO884052L/no
Publication of NO179434B publication Critical patent/NO179434B/no
Publication of NO179434C publication Critical patent/NO179434C/no

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Dermatology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO884052A 1987-09-15 1988-09-13 Fremgangsmåte for fremstilling av et farmasöytisk preparat, og anvendelse av en vannopplöselig monoester som et solubiliserende middel NO179434C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3730909 1987-09-15
DE3802355 1988-01-27

Publications (4)

Publication Number Publication Date
NO884052D0 NO884052D0 (no) 1988-09-13
NO884052L NO884052L (no) 1989-03-16
NO179434B NO179434B (no) 1996-07-01
NO179434C true NO179434C (no) 1996-10-09

Family

ID=25859774

Family Applications (1)

Application Number Title Priority Date Filing Date
NO884052A NO179434C (no) 1987-09-15 1988-09-13 Fremgangsmåte for fremstilling av et farmasöytisk preparat, og anvendelse av en vannopplöselig monoester som et solubiliserende middel

Country Status (24)

Country Link
JP (1) JP3090666B2 (de)
KR (1) KR0131084B1 (de)
AT (1) AT395819B (de)
AU (1) AU628787B2 (de)
BE (1) BE1001204A5 (de)
CA (1) CA1338775C (de)
CH (1) CH683672A5 (de)
DK (1) DK175132B1 (de)
ES (1) ES2012118A6 (de)
FI (1) FI94837C (de)
FR (1) FR2620336B1 (de)
GB (1) GB2209671B (de)
GR (1) GR1002243B (de)
HU (1) HU205010B (de)
IE (1) IE61195B1 (de)
IL (1) IL87746A (de)
IT (1) IT1224886B (de)
LU (1) LU87335A1 (de)
MY (1) MY103769A (de)
NL (1) NL195094C (de)
NO (1) NO179434C (de)
NZ (1) NZ226163A (de)
PT (1) PT88492B (de)
SE (1) SE503279C2 (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
KR0148748B1 (ko) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 사이클로스포린을 함유하는 약학조성물
GR1000466B (el) * 1989-01-28 1992-07-30 Sandoz Ag Μεθοδος παρασκευης νεων φαρμακευτικων μορφων κυκλοσπορινης.
BE1003009A5 (fr) * 1989-02-09 1991-10-22 Sandoz Sa Nouvelles compositions pharmaceutiques a base de cyclosporines.
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
JP3631490B2 (ja) 1992-05-13 2005-03-23 ノバルティス ファーマ株式会社 シクロスポリン含有眼科用組成物
EP0589843B1 (de) 1992-09-25 2001-11-28 Novartis AG Cyclosporin enthaltende pharmazeutische Zusammensetzungen
EP0649651B1 (de) 1993-09-28 2000-12-13 R.P. Scherer GmbH Herstellung von Weichgelatinekapseln
RU2158601C2 (ru) 1994-11-03 2000-11-10 Новартис Аг Новые лекарственные формы циклоспорина для орального применения с простым составом и высокой биодоступностью и способ их получения
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
DE19549852B4 (de) 1995-11-29 2009-06-04 Novartis Ag Cyclosporin enthaltende Präparate
TW414696B (en) * 1996-07-01 2000-12-11 Mitsubishi Kagaku Foods Kk Anti-bacteria agent
RU2211047C2 (ru) 1997-01-30 2003-08-27 Новартис Аг Желатиновые капсулы с твердым покрытием, включающие фармацевтические композиции, практически не содержащие масел
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
AU2003267747A1 (en) * 2003-10-14 2005-05-05 Ramesh Varada Bapat Sterile gelling agents
JP5422871B2 (ja) * 2006-10-24 2014-02-19 不二製油株式会社 イソフラボン類組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE624258A (de) * 1961-10-31
GB1134878A (en) * 1966-05-12 1968-11-27 Suga Kazuo Improvements in and relating to oryzanol solutions and compositions
FR5986M (de) * 1966-11-22 1968-06-21
BE787842A (fr) * 1971-08-25 1972-12-18 Sumito Chemical Cy Ltd Procede de preparation d'une suspension aqueuse de cristaux stables du type non beta d'esters d'acides gras superieurs du chloramphenicol
JPS53107408A (en) * 1977-02-28 1978-09-19 Yamanouchi Pharmaceut Co Ltd Micellar preparation for rectal infusion
FI65914C (fi) * 1978-03-07 1984-08-10 Sandoz Ag Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
JPS57128634A (en) * 1981-02-03 1982-08-10 Eisai Co Ltd Elastase-containing compound increasing absorption
EP0179583A1 (de) * 1984-10-04 1986-04-30 Merck & Co. Inc. System zur Verbesserung der Auflösungsgeschwindigkeit in Wasser und der Löslichkeit von schwer löslichen Arzneimitteln
JPS61280435A (ja) * 1985-04-04 1986-12-11 Kanji Takada サイクロスポリン類のリンパ指向性製剤

Also Published As

Publication number Publication date
FI94837C (fi) 1995-11-10
GR880100602A (el) 1989-06-22
DK175132B1 (da) 2004-06-14
IE882772L (en) 1989-03-15
SE8803221L (sv) 1989-03-16
GB8821443D0 (en) 1988-10-12
AU628787B2 (en) 1992-09-24
DK511188D0 (da) 1988-09-14
IT8848349A0 (it) 1988-09-14
AU2217288A (en) 1989-04-27
NL195094C (nl) 2003-12-17
SE8803221D0 (sv) 1988-09-13
NL8802275A (nl) 1989-04-03
JPH01151526A (ja) 1989-06-14
FI884192A (fi) 1989-03-16
BE1001204A5 (fr) 1989-08-16
NZ226163A (en) 1991-08-27
NO179434B (no) 1996-07-01
PT88492A (pt) 1988-10-01
ES2012118A6 (es) 1990-03-01
HUT49494A (en) 1989-10-30
GB2209671B (en) 1991-11-13
GR1002243B (en) 1996-04-22
FR2620336A1 (fr) 1989-03-17
FI884192A0 (fi) 1988-09-13
NO884052D0 (no) 1988-09-13
KR0131084B1 (ko) 1998-04-17
SE503279C2 (sv) 1996-05-13
ATA224988A (de) 1992-08-15
NO884052L (no) 1989-03-16
IE61195B1 (en) 1994-10-19
IL87746A0 (en) 1989-02-28
FR2620336B1 (fr) 1991-10-25
CH683672A5 (de) 1994-04-29
IT1224886B (it) 1990-10-24
CA1338775C (en) 1996-12-10
GB2209671A (en) 1989-05-24
FI94837B (fi) 1995-07-31
AT395819B (de) 1993-03-25
DK511188A (da) 1989-03-16
IL87746A (en) 1992-07-15
JP3090666B2 (ja) 2000-09-25
PT88492B (pt) 1993-03-31
LU87335A1 (fr) 1989-04-06
KR890004694A (ko) 1989-05-09
MY103769A (en) 1993-09-30
HU205010B (en) 1992-03-30

Similar Documents

Publication Publication Date Title
NO179434C (no) Fremgangsmåte for fremstilling av et farmasöytisk preparat, og anvendelse av en vannopplöselig monoester som et solubiliserende middel
NO885641D0 (no) Fremgangsmaate for fremstilling av farmasoeytisk preparat.
IT8820145A0 (it) Composizione farmaceutiche a rilascio controllato e procedimento per la loro preparazione.
DK0477049T3 (da) 3-amido-pyrazolderivater, fremgangsmåde til deres fremstilling og farmaceutiske præparater indeholdende dem
IL89503A0 (en) Taxol derivatives,pharmaceutical compositions containing the same and process for the preparation thereof
IT8822399A0 (it) Derivati di monofosforil lipide a e procedimento per la loro preparazione.
DE3483899D1 (de) Cephalosporinderivate, verfahren zu ihrer herstellung und pharmazeutische praeparate.
DK192589A (da) Pyridoncarboxylsyrederivat, fremgangsmaade til fremstilling deraf og middel indeholdende et pyridoncarboxylsyrederivat
DK560289A (da) Fluoxetin-analoge, fremgangsmaade til fremstilling heraf og farmaceutiske midler indeholdende saadanne
NO900309L (no) Benzocykloalkenyldihydroksyalkansyrederivater, og fremgangsmaate til fremstilling derav.
DK660788A (da) 2,2-difluorcyklopropylethanderivater, fremgangsmaade til deres fremstilling og deres anvendelse som skadedyrsbekaempelsesmiddel
ATE143010T1 (de) Pyridazin-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen
IT1240350B (it) Derivati di tieno-triazolo-diazepine,un procedimento per la loro preparazione e composizioni terapeutiche che li contengono
DK162886C (da) 1,4-dihydropyridin-derivater, fremgangsmaade til fremstilling deraf og farmaceutisk praeparat indeholdende forbindelserne
FI890853A0 (fi) Farmaceutiskt preparat som tryggar transdermal absorption av den aktiva bestaondsdelen och foerfarande foer framstaellning daerav.
DE3766299D1 (de) 4-chinolon-3-carbonsaeurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
NO955320L (no) Substituerte 4-fenyltiazolderivater, fremgangsmåte for fremstilling derav og farmasöytiske blandinger som inneholder dem
NO912872D0 (no) Fremgangsmaate og middel for fremstilling av et stabilt farmasoeytisk preparat.
IT1240935B (it) Derivati di tieno-triazolo-diazepine, un procedimento per la loro preparazione e composizioni terapeutiche che li contengono
DE3852332D1 (de) 4-Thiochinazolin-Derivate, Verfahren zu deren Herstellung und pharmazeutische Zusammenstellungen.
NL192387B (nl) Zuivere silibininederivaten, werkwijze voor de bereiding daarvan en farmaceutisch preparaat dat een dergelijk derivaat bevat.
DK0492667T3 (da) 1,4-Benzothiazin-2-eddikesyrederivater, fremgangsmåder til fremstilling deraf og anvendelse deraf
IL59719A (en) 2-(pyrid-2-yl)tetrahydrothiophene derivatives,process for their preparation and pharmaceutical compositions comprising the same
DE3670635D1 (de) Neue benzisoselenazolonyl-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische praeparate.
DE3380989D1 (de) 2-aminobenzosaeurederivate, verfahren zu ihrer herstellung und pharmazeutische zubereitungen.

Legal Events

Date Code Title Description
MK1K Patent expired