NO179434C - Fremgangsmåte for fremstilling av et farmasöytisk preparat, og anvendelse av en vannopplöselig monoester som et solubiliserende middel - Google Patents

Fremgangsmåte for fremstilling av et farmasöytisk preparat, og anvendelse av en vannopplöselig monoester som et solubiliserende middel

Info

Publication number
NO179434C
NO179434C NO884052A NO884052A NO179434C NO 179434 C NO179434 C NO 179434C NO 884052 A NO884052 A NO 884052A NO 884052 A NO884052 A NO 884052A NO 179434 C NO179434 C NO 179434C
Authority
NO
Norway
Prior art keywords
preparing
water
pharmaceutical composition
solubilizing agent
soluble monoester
Prior art date
Application number
NO884052A
Other languages
English (en)
Other versions
NO179434B (no
NO884052L (no
NO884052D0 (no
Inventor
Lorenz Hahn
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of NO884052D0 publication Critical patent/NO884052D0/no
Publication of NO884052L publication Critical patent/NO884052L/no
Publication of NO179434B publication Critical patent/NO179434B/no
Publication of NO179434C publication Critical patent/NO179434C/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
NO884052A 1987-09-15 1988-09-13 Fremgangsmåte for fremstilling av et farmasöytisk preparat, og anvendelse av en vannopplöselig monoester som et solubiliserende middel NO179434C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3730909 1987-09-15
DE3802355 1988-01-27

Publications (4)

Publication Number Publication Date
NO884052D0 NO884052D0 (no) 1988-09-13
NO884052L NO884052L (no) 1989-03-16
NO179434B NO179434B (no) 1996-07-01
NO179434C true NO179434C (no) 1996-10-09

Family

ID=25859774

Family Applications (1)

Application Number Title Priority Date Filing Date
NO884052A NO179434C (no) 1987-09-15 1988-09-13 Fremgangsmåte for fremstilling av et farmasöytisk preparat, og anvendelse av en vannopplöselig monoester som et solubiliserende middel

Country Status (24)

Country Link
JP (1) JP3090666B2 (no)
KR (1) KR0131084B1 (no)
AT (1) AT395819B (no)
AU (1) AU628787B2 (no)
BE (1) BE1001204A5 (no)
CA (1) CA1338775C (no)
CH (1) CH683672A5 (no)
DK (1) DK175132B1 (no)
ES (1) ES2012118A6 (no)
FI (1) FI94837C (no)
FR (1) FR2620336B1 (no)
GB (1) GB2209671B (no)
GR (1) GR1002243B (no)
HU (1) HU205010B (no)
IE (1) IE61195B1 (no)
IL (1) IL87746A (no)
IT (1) IT1224886B (no)
LU (1) LU87335A1 (no)
MY (1) MY103769A (no)
NL (1) NL195094C (no)
NO (1) NO179434C (no)
NZ (1) NZ226163A (no)
PT (1) PT88492B (no)
SE (1) SE503279C2 (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
GB2222770B (en) * 1988-09-16 1992-07-29 Sandoz Ltd Pharmaceutical compositions containing cyclosporins
GR1000466B (el) * 1989-01-28 1992-07-30 Sandoz Ag Μεθοδος παρασκευης νεων φαρμακευτικων μορφων κυκλοσπορινης.
BE1003009A5 (fr) * 1989-02-09 1991-10-22 Sandoz Sa Nouvelles compositions pharmaceutiques a base de cyclosporines.
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
ATE147619T1 (de) 1992-05-13 1997-02-15 Sandoz Ag Opthalmische zusammensetzungen enthaltend ein cyclosporin
ES2168271T3 (es) 1992-09-25 2002-06-16 Novartis Ag Composiciones farmaceuticas que contienen ciclosporinas.
SI1033128T2 (sl) * 1993-09-28 2012-02-29 Scherer Gmbh R P Izdelava mehke Ĺľelatinaste kapsule
ATE218359T1 (de) 1994-11-03 2002-06-15 Novartis Erfind Verwalt Gmbh Neue zubereitungsformen des cyclosporins zur oralen applikation mit einfacher zusammensetzung und hoher bioverfügbarkeit und verfahren zu deren herstellung
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
DE19549852B4 (de) 1995-11-29 2009-06-04 Novartis Ag Cyclosporin enthaltende Präparate
TW414696B (en) * 1996-07-01 2000-12-11 Mitsubishi Kagaku Foods Kk Anti-bacteria agent
TR199901686T2 (xx) 1997-01-30 1999-09-21 Norvartis Ag Esasen ya�s�z farmakolojik kompozisyonlar� i�eren sert jelatin kaps�ller.
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
EP1558215A4 (en) * 2003-10-14 2007-09-12 Wockhardt Ltd STERILE GELIFYING AGENTS
JP5422871B2 (ja) * 2006-10-24 2014-02-19 不二製油株式会社 イソフラボン類組成物

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE624258A (no) * 1961-10-31
GB1134878A (en) * 1966-05-12 1968-11-27 Suga Kazuo Improvements in and relating to oryzanol solutions and compositions
FR5986M (no) * 1966-11-22 1968-06-21
BE787842A (fr) * 1971-08-25 1972-12-18 Sumito Chemical Cy Ltd Procede de preparation d'une suspension aqueuse de cristaux stables du type non beta d'esters d'acides gras superieurs du chloramphenicol
JPS53107408A (en) * 1977-02-28 1978-09-19 Yamanouchi Pharmaceut Co Ltd Micellar preparation for rectal infusion
FI65914C (fi) * 1978-03-07 1984-08-10 Sandoz Ag Foerfarande foer framstaellning av farmaceutiska kompositionerinnehaollande cyklosporin a
JPS57128634A (en) * 1981-02-03 1982-08-10 Eisai Co Ltd Elastase-containing compound increasing absorption
EP0179583A1 (en) * 1984-10-04 1986-04-30 Merck & Co. Inc. A system for enhancing the water dissolution rate and solubility of poorly soluble drugs
JPS61280435A (ja) * 1985-04-04 1986-12-11 Kanji Takada サイクロスポリン類のリンパ指向性製剤

Also Published As

Publication number Publication date
GR1002243B (en) 1996-04-22
FI884192A (fi) 1989-03-16
HU205010B (en) 1992-03-30
GB2209671A (en) 1989-05-24
FI94837B (fi) 1995-07-31
PT88492B (pt) 1993-03-31
BE1001204A5 (fr) 1989-08-16
GR880100602A (el) 1989-06-22
SE503279C2 (sv) 1996-05-13
GB2209671B (en) 1991-11-13
JPH01151526A (ja) 1989-06-14
AU628787B2 (en) 1992-09-24
DK511188D0 (da) 1988-09-14
KR890004694A (ko) 1989-05-09
IE61195B1 (en) 1994-10-19
NL195094C (nl) 2003-12-17
SE8803221D0 (sv) 1988-09-13
KR0131084B1 (ko) 1998-04-17
ATA224988A (de) 1992-08-15
IL87746A0 (en) 1989-02-28
MY103769A (en) 1993-09-30
DK175132B1 (da) 2004-06-14
ES2012118A6 (es) 1990-03-01
FR2620336B1 (fr) 1991-10-25
AU2217288A (en) 1989-04-27
NL8802275A (nl) 1989-04-03
HUT49494A (en) 1989-10-30
FR2620336A1 (fr) 1989-03-17
NO179434B (no) 1996-07-01
AT395819B (de) 1993-03-25
IL87746A (en) 1992-07-15
LU87335A1 (fr) 1989-04-06
IT1224886B (it) 1990-10-24
NZ226163A (en) 1991-08-27
IT8848349A0 (it) 1988-09-14
NO884052L (no) 1989-03-16
PT88492A (pt) 1988-10-01
CH683672A5 (de) 1994-04-29
FI94837C (fi) 1995-11-10
JP3090666B2 (ja) 2000-09-25
SE8803221L (sv) 1989-03-16
GB8821443D0 (en) 1988-10-12
CA1338775C (en) 1996-12-10
DK511188A (da) 1989-03-16
NO884052D0 (no) 1988-09-13
FI884192A0 (fi) 1988-09-13
IE882772L (en) 1989-03-15

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