IL87746A0 - Pharmaceutical compositions containing pharmacologically active compounds and water soluble monoesters as solubilisers therefor - Google Patents

Pharmaceutical compositions containing pharmacologically active compounds and water soluble monoesters as solubilisers therefor

Info

Publication number
IL87746A0
IL87746A0 IL87746A IL8774688A IL87746A0 IL 87746 A0 IL87746 A0 IL 87746A0 IL 87746 A IL87746 A IL 87746A IL 8774688 A IL8774688 A IL 8774688A IL 87746 A0 IL87746 A0 IL 87746A0
Authority
IL
Israel
Prior art keywords
solubilisers
therefor
pharmaceutical compositions
water soluble
active compounds
Prior art date
Application number
IL87746A
Other versions
IL87746A (en
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of IL87746A0 publication Critical patent/IL87746A0/en
Publication of IL87746A publication Critical patent/IL87746A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/14Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Dermatology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicinal Preparation (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IL87746A 1987-09-15 1988-09-14 Pharmaceutical compositions containing pharmacologically active compounds and water soluble monoesters as solubilisers therefor IL87746A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE3730909 1987-09-15
DE3802355 1988-01-27

Publications (2)

Publication Number Publication Date
IL87746A0 true IL87746A0 (en) 1989-02-28
IL87746A IL87746A (en) 1992-07-15

Family

ID=25859774

Family Applications (1)

Application Number Title Priority Date Filing Date
IL87746A IL87746A (en) 1987-09-15 1988-09-14 Pharmaceutical compositions containing pharmacologically active compounds and water soluble monoesters as solubilisers therefor

Country Status (24)

Country Link
JP (1) JP3090666B2 (en)
KR (1) KR0131084B1 (en)
AT (1) AT395819B (en)
AU (1) AU628787B2 (en)
BE (1) BE1001204A5 (en)
CA (1) CA1338775C (en)
CH (1) CH683672A5 (en)
DK (1) DK175132B1 (en)
ES (1) ES2012118A6 (en)
FI (1) FI94837C (en)
FR (1) FR2620336B1 (en)
GB (1) GB2209671B (en)
GR (1) GR1002243B (en)
HU (1) HU205010B (en)
IE (1) IE61195B1 (en)
IL (1) IL87746A (en)
IT (1) IT1224886B (en)
LU (1) LU87335A1 (en)
MY (1) MY103769A (en)
NL (1) NL195094C (en)
NO (1) NO179434C (en)
NZ (1) NZ226163A (en)
PT (1) PT88492B (en)
SE (1) SE503279C2 (en)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0148748B1 (en) * 1988-09-16 1998-08-17 장 크라메르, 한스 루돌프 하우스 A multiphase cyclosporin composition
US6007840A (en) * 1988-09-16 1999-12-28 Novartis Ag Pharmaceutical compositions comprising cyclosporins
GR1000466B (en) * 1989-01-28 1992-07-30 Sandoz Ag Preparation method of novel pharmaceutical forms of cyclosporine
FR2642650B1 (en) * 1989-02-09 1994-12-09 Sandoz Sa NEW PHARMACEUTICAL COMPOSITIONS BASED ON CYCLOSPORINS
GB8916901D0 (en) 1989-07-24 1989-09-06 Sandoz Ltd Improvements in or relating to organic compounds
US6262022B1 (en) 1992-06-25 2001-07-17 Novartis Ag Pharmaceutical compositions containing cyclosporin as the active agent
DE69307505T2 (en) 1992-05-13 1997-07-24 Sandoz-Patent-Gmbh, 79539 Loerrach OPTHALMIC COMPOSITIONS CONTAINING A CYCLOSPORIN
PT589843E (en) 1992-09-25 2002-04-29 Novartis Ag PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORTS
DE69435104D1 (en) * 1993-09-28 2008-07-31 Scherer Gmbh R P Production of soft gelatine capsules
EP0789580B1 (en) 1994-11-03 2002-06-05 Novartis AG Novel cyclosporine preparation forms for oral administration of simple composition and high bio-availability, and process for producing them
US5827822A (en) * 1996-03-25 1998-10-27 Sangstat Medical Corporation Cyclosporin a formulations as nanoparticles
US5766629A (en) 1995-08-25 1998-06-16 Sangstat Medical Corporation Oral cyclosporin formulations
US5962019A (en) * 1995-08-25 1999-10-05 Sangstat Medical Corporation Oral cyclosporin formulations
US5834017A (en) * 1995-08-25 1998-11-10 Sangstat Medical Corporation Oral cyclopsporin formulations
DE19544507B4 (en) 1995-11-29 2007-11-15 Novartis Ag Cyclosporin containing preparations
TW414696B (en) * 1996-07-01 2000-12-11 Mitsubishi Kagaku Foods Kk Anti-bacteria agent
BR9807528A (en) 1997-01-30 2000-03-14 Novartis Ag Oil-free pharmaceutical compositions containing cyclosporine a
GB2326337A (en) * 1997-06-20 1998-12-23 Phares Pharma Holland Homogeneous lipid compositions for drug delivery
US7732404B2 (en) 1999-12-30 2010-06-08 Dexcel Ltd Pro-nanodispersion for the delivery of cyclosporin
AU2003267747A1 (en) * 2003-10-14 2005-05-05 Ramesh Varada Bapat Sterile gelling agents
JP5422871B2 (en) * 2006-10-24 2014-02-19 不二製油株式会社 Isoflavones composition

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NL284933A (en) * 1961-10-31
GB1134878A (en) * 1966-05-12 1968-11-27 Suga Kazuo Improvements in and relating to oryzanol solutions and compositions
FR5986M (en) * 1966-11-22 1968-06-21
BE787842A (en) * 1971-08-25 1972-12-18 Sumito Chemical Cy Ltd PROCESS FOR PREPARING AN AQUEOUS SUSPENSION OF STABLE CRYSTALS OF THE NON-BETA TYPE OF HIGHER FATTY ACID ESTERS OF CHLORAMPHENICOL
JPS53107408A (en) * 1977-02-28 1978-09-19 Yamanouchi Pharmaceut Co Ltd Micellar preparation for rectal infusion
FI65914C (en) * 1978-03-07 1984-08-10 Sandoz Ag FRAMEWORK FOR PHARMACEUTICAL COMPOSITION OF CYCLOSPORINE A
JPS57128634A (en) * 1981-02-03 1982-08-10 Eisai Co Ltd Elastase-containing compound increasing absorption
EP0179583A1 (en) * 1984-10-04 1986-04-30 Merck & Co. Inc. A system for enhancing the water dissolution rate and solubility of poorly soluble drugs
JPS61280435A (en) * 1985-04-04 1986-12-11 Kanji Takada Lymph orienting preparation of cyclosporin

Also Published As

Publication number Publication date
SE8803221L (en) 1989-03-16
PT88492B (en) 1993-03-31
GB8821443D0 (en) 1988-10-12
MY103769A (en) 1993-09-30
IT1224886B (en) 1990-10-24
ATA224988A (en) 1992-08-15
NO884052L (en) 1989-03-16
FR2620336B1 (en) 1991-10-25
ES2012118A6 (en) 1990-03-01
NO179434C (en) 1996-10-09
SE503279C2 (en) 1996-05-13
BE1001204A5 (en) 1989-08-16
AT395819B (en) 1993-03-25
FI94837C (en) 1995-11-10
JP3090666B2 (en) 2000-09-25
DK175132B1 (en) 2004-06-14
NO179434B (en) 1996-07-01
AU628787B2 (en) 1992-09-24
GB2209671B (en) 1991-11-13
NL195094C (en) 2003-12-17
SE8803221D0 (en) 1988-09-13
LU87335A1 (en) 1989-04-06
FI884192A0 (en) 1988-09-13
KR0131084B1 (en) 1998-04-17
FI94837B (en) 1995-07-31
GR880100602A (en) 1989-06-22
NL8802275A (en) 1989-04-03
IT8848349A0 (en) 1988-09-14
DK511188D0 (en) 1988-09-14
JPH01151526A (en) 1989-06-14
IE882772L (en) 1989-03-15
DK511188A (en) 1989-03-16
FI884192A (en) 1989-03-16
KR890004694A (en) 1989-05-09
NZ226163A (en) 1991-08-27
FR2620336A1 (en) 1989-03-17
NO884052D0 (en) 1988-09-13
GB2209671A (en) 1989-05-24
AU2217288A (en) 1989-04-27
IL87746A (en) 1992-07-15
CH683672A5 (en) 1994-04-29
IE61195B1 (en) 1994-10-19
PT88492A (en) 1988-10-01
HUT49494A (en) 1989-10-30
CA1338775C (en) 1996-12-10
HU205010B (en) 1992-03-30
GR1002243B (en) 1996-04-22

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Legal Events

Date Code Title Description
HC Change of name of proprietor(s)
KB Patent renewed
KB Patent renewed
KB Patent renewed
EXTN Extension order renewed