IT1224886B - WATER SOLUBLE MONOESTERS THAT CAN BE USED AS SOLUBILIZERS FOR PHARMACOLOGICALLY ACTIVE SUBSTANCES - Google Patents
WATER SOLUBLE MONOESTERS THAT CAN BE USED AS SOLUBILIZERS FOR PHARMACOLOGICALLY ACTIVE SUBSTANCESInfo
- Publication number
- IT1224886B IT1224886B IT8848349A IT4834988A IT1224886B IT 1224886 B IT1224886 B IT 1224886B IT 8848349 A IT8848349 A IT 8848349A IT 4834988 A IT4834988 A IT 4834988A IT 1224886 B IT1224886 B IT 1224886B
- Authority
- IT
- Italy
- Prior art keywords
- solubilizers
- water soluble
- active substances
- pharmacologically active
- soluble monoesters
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
- A61K47/14—Esters of carboxylic acids, e.g. fatty acid monoglycerides, medium-chain triglycerides, parabens or PEG fatty acid esters
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3730909 | 1987-09-15 | ||
| DE3802355 | 1988-01-27 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| IT8848349A0 IT8848349A0 (en) | 1988-09-14 |
| IT1224886B true IT1224886B (en) | 1990-10-24 |
Family
ID=25859774
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| IT8848349A IT1224886B (en) | 1987-09-15 | 1988-09-14 | WATER SOLUBLE MONOESTERS THAT CAN BE USED AS SOLUBILIZERS FOR PHARMACOLOGICALLY ACTIVE SUBSTANCES |
Country Status (24)
| Country | Link |
|---|---|
| JP (1) | JP3090666B2 (en) |
| KR (1) | KR0131084B1 (en) |
| AT (1) | AT395819B (en) |
| AU (1) | AU628787B2 (en) |
| BE (1) | BE1001204A5 (en) |
| CA (1) | CA1338775C (en) |
| CH (1) | CH683672A5 (en) |
| DK (1) | DK175132B1 (en) |
| ES (1) | ES2012118A6 (en) |
| FI (1) | FI94837C (en) |
| FR (1) | FR2620336B1 (en) |
| GB (1) | GB2209671B (en) |
| GR (1) | GR1002243B (en) |
| HU (1) | HU205010B (en) |
| IE (1) | IE61195B1 (en) |
| IL (1) | IL87746A (en) |
| IT (1) | IT1224886B (en) |
| LU (1) | LU87335A1 (en) |
| MY (1) | MY103769A (en) |
| NL (1) | NL195094C (en) |
| NO (1) | NO179434C (en) |
| NZ (1) | NZ226163A (en) |
| PT (1) | PT88492B (en) |
| SE (1) | SE503279C2 (en) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR0148748B1 (en) * | 1988-09-16 | 1998-08-17 | 장 크라메르, 한스 루돌프 하우스 | A multiphase cyclosporin composition |
| US6007840A (en) * | 1988-09-16 | 1999-12-28 | Novartis Ag | Pharmaceutical compositions comprising cyclosporins |
| GR1000466B (en) * | 1989-01-28 | 1992-07-30 | Sandoz Ag | Preparation method of novel pharmaceutical forms of cyclosporine |
| FR2642650B1 (en) * | 1989-02-09 | 1994-12-09 | Sandoz Sa | NEW PHARMACEUTICAL COMPOSITIONS BASED ON CYCLOSPORINS |
| GB8916901D0 (en) | 1989-07-24 | 1989-09-06 | Sandoz Ltd | Improvements in or relating to organic compounds |
| US6262022B1 (en) | 1992-06-25 | 2001-07-17 | Novartis Ag | Pharmaceutical compositions containing cyclosporin as the active agent |
| DK0642332T3 (en) | 1992-05-13 | 1997-06-16 | Sandoz Ltd | Ophthalmic preparations containing cyclosporin |
| PT589843E (en) | 1992-09-25 | 2002-04-29 | Novartis Ag | PHARMACEUTICAL COMPOSITIONS CONTAINING CYCLOSPORTS |
| DE69435104D1 (en) | 1993-09-28 | 2008-07-31 | Scherer Gmbh R P | Production of soft gelatine capsules |
| CA2231404C (en) | 1994-11-03 | 2009-02-17 | Arzneimittelwerk Dresden Gmbh | Novel cyclosporine preparation forms for oral administration of simple composition and high bio-availability, and process for producing them |
| US5766629A (en) * | 1995-08-25 | 1998-06-16 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| US5962019A (en) * | 1995-08-25 | 1999-10-05 | Sangstat Medical Corporation | Oral cyclosporin formulations |
| US5827822A (en) * | 1996-03-25 | 1998-10-27 | Sangstat Medical Corporation | Cyclosporin a formulations as nanoparticles |
| US5834017A (en) * | 1995-08-25 | 1998-11-10 | Sangstat Medical Corporation | Oral cyclopsporin formulations |
| DE19544507B4 (en) | 1995-11-29 | 2007-11-15 | Novartis Ag | Cyclosporin containing preparations |
| TW414696B (en) * | 1996-07-01 | 2000-12-11 | Mitsubishi Kagaku Foods Kk | Anti-bacteria agent |
| CA2278675A1 (en) | 1997-01-30 | 1998-08-06 | Novartis Ag | Hard gelatine capsules containing pharmaceutical compositions substantially free of any oil |
| GB2326337A (en) * | 1997-06-20 | 1998-12-23 | Phares Pharma Holland | Homogeneous lipid compositions for drug delivery |
| US7732404B2 (en) | 1999-12-30 | 2010-06-08 | Dexcel Ltd | Pro-nanodispersion for the delivery of cyclosporin |
| EP1558215A4 (en) * | 2003-10-14 | 2007-09-12 | Wockhardt Ltd | Sterile gelling agents |
| JP5422871B2 (en) * | 2006-10-24 | 2014-02-19 | 不二製油株式会社 | Isoflavones composition |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NL284933A (en) * | 1961-10-31 | |||
| GB1134878A (en) * | 1966-05-12 | 1968-11-27 | Suga Kazuo | Improvements in and relating to oryzanol solutions and compositions |
| FR5986M (en) * | 1966-11-22 | 1968-06-21 | ||
| BE787842A (en) * | 1971-08-25 | 1972-12-18 | Sumito Chemical Cy Ltd | PROCESS FOR PREPARING AN AQUEOUS SUSPENSION OF STABLE CRYSTALS OF THE NON-BETA TYPE OF HIGHER FATTY ACID ESTERS OF CHLORAMPHENICOL |
| JPS53107408A (en) * | 1977-02-28 | 1978-09-19 | Yamanouchi Pharmaceut Co Ltd | Micellar preparation for rectal infusion |
| DE2907460A1 (en) * | 1978-03-07 | 1979-09-13 | Sandoz Ag | NEW RESORBABLE GALENIC COMPOSITIONS |
| JPS57128634A (en) * | 1981-02-03 | 1982-08-10 | Eisai Co Ltd | Elastase-containing compound increasing absorption |
| EP0179583A1 (en) * | 1984-10-04 | 1986-04-30 | Merck & Co. Inc. | A system for enhancing the water dissolution rate and solubility of poorly soluble drugs |
| JPS61280435A (en) * | 1985-04-04 | 1986-12-11 | Kanji Takada | Lymph orienting preparation of cyclosporin |
-
1988
- 1988-09-01 HU HU884518A patent/HU205010B/en unknown
- 1988-09-12 CH CH3398/88A patent/CH683672A5/en not_active IP Right Cessation
- 1988-09-12 BE BE8801044A patent/BE1001204A5/en not_active IP Right Cessation
- 1988-09-12 LU LU87335A patent/LU87335A1/en unknown
- 1988-09-12 FR FR888811953A patent/FR2620336B1/en not_active Expired - Lifetime
- 1988-09-13 SE SE8803221A patent/SE503279C2/en not_active IP Right Cessation
- 1988-09-13 PT PT88492A patent/PT88492B/en not_active IP Right Cessation
- 1988-09-13 FI FI884192A patent/FI94837C/en not_active IP Right Cessation
- 1988-09-13 NO NO884052A patent/NO179434C/en not_active IP Right Cessation
- 1988-09-13 NZ NZ226163A patent/NZ226163A/en unknown
- 1988-09-13 IE IE277288A patent/IE61195B1/en not_active IP Right Cessation
- 1988-09-13 CA CA000577214A patent/CA1338775C/en not_active Expired - Lifetime
- 1988-09-13 GB GB8821443A patent/GB2209671B/en not_active Expired - Lifetime
- 1988-09-13 AU AU22172/88A patent/AU628787B2/en not_active Expired
- 1988-09-14 KR KR1019880011874A patent/KR0131084B1/en not_active IP Right Cessation
- 1988-09-14 IL IL87746A patent/IL87746A/en active Protection Beyond IP Right Term
- 1988-09-14 JP JP63231396A patent/JP3090666B2/en not_active Expired - Lifetime
- 1988-09-14 DK DK198805111A patent/DK175132B1/en not_active IP Right Cessation
- 1988-09-14 MY MYPI88001027A patent/MY103769A/en unknown
- 1988-09-14 AT AT0224988A patent/AT395819B/en not_active IP Right Cessation
- 1988-09-14 IT IT8848349A patent/IT1224886B/en active
- 1988-09-14 GR GR880100602A patent/GR1002243B/en not_active IP Right Cessation
- 1988-09-15 ES ES8802831A patent/ES2012118A6/en not_active Expired - Lifetime
- 1988-09-15 NL NL8802275A patent/NL195094C/en not_active IP Right Cessation
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970714 |