NO179109C - Ekspresjonsvektor, rekombinante vertsceller samt fremgangsmåte for fremstilling av terapeutisk aktivt, rekombinant CSF - Google Patents

Ekspresjonsvektor, rekombinante vertsceller samt fremgangsmåte for fremstilling av terapeutisk aktivt, rekombinant CSF

Info

Publication number
NO179109C
NO179109C NO863952A NO863952A NO179109C NO 179109 C NO179109 C NO 179109C NO 863952 A NO863952 A NO 863952A NO 863952 A NO863952 A NO 863952A NO 179109 C NO179109 C NO 179109C
Authority
NO
Norway
Prior art keywords
expression vector
host cells
recombinant
therapeutically active
csf
Prior art date
Application number
NO863952A
Other languages
English (en)
Other versions
NO863952D0 (no
NO179109B (no
NO863952L (no
Inventor
Ernest Seigo Kawasaki
Janelle Noble Van Arsdell
Peter Ralph
Mary Kim Warren
Martha Ballie Ladner
Alice Ming Wang
Mazie Yee Coyne
Original Assignee
Chiron Corp
Cetus Oncology Corp
Cetus Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chiron Corp, Cetus Oncology Corp, Cetus Corp filed Critical Chiron Corp
Publication of NO863952D0 publication Critical patent/NO863952D0/no
Publication of NO863952L publication Critical patent/NO863952L/no
Publication of NO179109B publication Critical patent/NO179109B/no
Publication of NO179109C publication Critical patent/NO179109C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70—Vectors or expression systems specially adapted for E. coli
    • C12N15/73—Expression systems using phage (lambda) regulatory sequences
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/53—Colony-stimulating factor [CSF]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Wood Science & Technology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Physics & Mathematics (AREA)
  • Toxicology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Plant Pathology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
NO863952A 1985-02-05 1986-10-03 Ekspresjonsvektor, rekombinante vertsceller samt fremgangsmåte for fremstilling av terapeutisk aktivt, rekombinant CSF NO179109C (no)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
US69835985A 1985-02-05 1985-02-05
US72883485A 1985-04-30 1985-04-30
US74492485A 1985-06-14 1985-06-14
US75681485A 1985-07-18 1985-07-18
US82106886A 1986-01-21 1986-01-21
PCT/US1986/000238 WO1986004607A1 (en) 1985-02-05 1986-02-03 Recombinant colony stimulating factor-1

Publications (4)

Publication Number Publication Date
NO863952D0 NO863952D0 (no) 1986-10-03
NO863952L NO863952L (no) 1986-10-03
NO179109B NO179109B (no) 1996-04-29
NO179109C true NO179109C (no) 1996-08-07

Family

ID=27542097

Family Applications (1)

Application Number Title Priority Date Filing Date
NO863952A NO179109C (no) 1985-02-05 1986-10-03 Ekspresjonsvektor, rekombinante vertsceller samt fremgangsmåte for fremstilling av terapeutisk aktivt, rekombinant CSF

Country Status (11)

Country Link
US (1) US5470569A (no)
EP (1) EP0209601B1 (no)
JP (2) JP2561255B2 (no)
AU (2) AU594045B2 (no)
BG (1) BG49941A3 (no)
DE (1) DE3689391T2 (no)
DK (1) DK172843B1 (no)
FI (1) FI100972B (no)
IL (1) IL77789A (no)
NO (1) NO179109C (no)
WO (1) WO1986004607A1 (no)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6117422A (en) * 1985-02-05 2000-09-12 Chiron Corporation N∇2-CSF-1(long form) and carboxy truncated fragments thereof
US5422105A (en) * 1985-02-05 1995-06-06 Cetus Oncology Corporation Use of recombinant colony stimulating factor 1
US5556620A (en) * 1985-02-05 1996-09-17 Cetus Oncology Corporation Use of recombinant colony stimulating factor-1 to enhance wound healing
US5573930A (en) * 1985-02-05 1996-11-12 Cetus Oncology Corporation DNA encoding various forms of colony stimulating factor-1
US5792450A (en) * 1985-02-05 1998-08-11 Chiron Corporation Purified human CSF-1
WO1986004607A1 (en) * 1985-02-05 1986-08-14 Cetus Corporation Recombinant colony stimulating factor-1
US5104650A (en) * 1985-02-05 1992-04-14 Cetus Corporation Uses of recombinant colony stimulating factor-1
US6156300A (en) * 1985-02-05 2000-12-05 Chiron Corporation Point mutants of N∇2 CSF-1 and carboxy truncated fragments thereof
US5837229A (en) * 1985-02-05 1998-11-17 Chiron Corporation Uses of recombinant colony stimulating factor-1
EP0307402B1 (en) * 1986-05-06 1993-08-11 Genetics Institute, Inc. Production of m-csf
EP0249477A3 (en) * 1986-06-12 1988-01-20 Immunex Corporation Functional recombinant analog polypeptides devoid of hydrophobic amino acids
US5650297A (en) * 1986-09-17 1997-07-22 Otsuka Pharmaceutical Co., Ltd. DNA encoding human colony-stimulating factors
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
JP2644794B2 (ja) * 1986-10-24 1997-08-25 カイロン コーポレイション 新規な型のコロニー刺激因子―１
AU8313187A (en) * 1986-12-31 1988-07-07 Cetus Corporation Pharmaceutical composition of colony stimulating factor-i and granulocyte colony stimulating factor
CA1339757C (en) * 1987-04-16 1998-03-17 Robert F. Halenbeck Production of purified biologically active, bacterially produced recombinant human csf-1
US4929700A (en) * 1987-04-16 1990-05-29 Cetus Corporation Production of purified, biologically active, bacterially produced recombinant human CSF-1
IL86090A (en) * 1987-04-16 1993-03-15 Cetus Oncology Corp Production of purified, biologically active, bacterially produced recombinant human csf-1
JP2831012B2 (ja) * 1987-09-22 1998-12-02 カイロン コーポレイション 組換えコロニー刺激因子‐１の使用
JP2791418B2 (ja) 1987-12-02 1998-08-27 株式会社ミドリ十字 異種蛋白質の製造方法、組換えｄｎａ、形質転換体
US4847325A (en) * 1988-01-20 1989-07-11 Cetus Corporation Conjugation of polymer to colony stimulating factor-1
DK54589A (da) * 1988-02-08 1989-08-09 Otsuka Pharma Co Ltd Humane kolonistmulerende faktorer
ATE111157T1 (de) * 1988-04-29 1994-09-15 Genetics Inst Lagerungsstabile zusammensetzungen von homogenem dimerem m-csf.
US5888495A (en) * 1988-05-23 1999-03-30 Genetics Institute, Inc. Method of producing storage stable M-CSF lyophilizates
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ
US5288487A (en) * 1989-02-28 1994-02-22 Morinaga Milk Industry Co., Ltd. Human monocyte-macrophage-CSF preparations
DE69022606T2 (de) * 1989-02-28 1996-05-02 Morinaga Milk Industry Co Ltd Menschlichen Monozyt-Makrophagen-Koloniestimulierungsfaktor enthaltende Zusammensetzung.
JPH02225418A (ja) * 1989-02-28 1990-09-07 Morinaga Milk Ind Co Ltd 抗悪性腫瘍剤
WO1990012877A1 (en) * 1989-04-19 1990-11-01 Cetus Corporation Multifunctional m-csf proteins and genes encoding therefor
AU1137699A (en) * 1997-11-07 1999-05-31 Dalhousie University Novel reovirus-derived proteins, nucleic acids encoding same, and uses therefor
US7108852B2 (en) * 2000-03-20 2006-09-19 Warner-Lambert Company Llc Methods of treating inflammation using antibodies to M-CSF
AR045563A1 (es) 2003-09-10 2005-11-02 Warner Lambert Co Anticuerpos dirigidos a m-csf
US20070099239A1 (en) * 2005-06-24 2007-05-03 Raymond Tabibiazar Methods and compositions for diagnosis and monitoring of atherosclerotic cardiovascular disease

Family Cites Families (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS6030291B2 (ja) * 1978-03-20 1985-07-16 森永乳業株式会社 人顆粒球の分化増殖を促進するｈｇｉ糖蛋白質、ｈｇｉ糖蛋白質の製造法及びｈｇｉ糖蛋白質を含有する白血球減少症治療剤
US4230697A (en) * 1978-07-03 1980-10-28 Morinaga Milk Industry Co. Ltd. Virus-inactivated HGI-glycoprotein capable of stimulating proliferation and differentiation of human granulocyte, process for preparing same and leukopenia curative containing same
US4342828A (en) * 1979-07-20 1982-08-03 Morinaga Milk Industry Co., Ltd. Method for producing substance capable of stimulating differentiation and proliferation of human granulopoietic stem cells
JPS5758629A (en) * 1980-09-25 1982-04-08 Morinaga Milk Ind Co Ltd Separating and purifying method of colonization stimulating factor and callicrein in human urine
JPS6030654B2 (ja) * 1980-12-31 1985-07-17 株式会社林原生物化学研究所 ヒトコロニ−刺激因子の製造方法
US4438032A (en) 1981-01-30 1984-03-20 The Regents Of The University Of California Unique T-lymphocyte line and products derived therefrom
US4432895A (en) * 1982-11-24 1984-02-21 Hoffmann-La Roche Inc. Monomeric interferons
US4485017A (en) * 1982-12-22 1984-11-27 Cetus Corporation Isolation of human interferon by immunosorbent and high performance liquid chromatography
JPS59137417A (ja) * 1983-01-28 1984-08-07 Morinaga Milk Ind Co Ltd 人尿由来コロニ−形成刺激因子及びカリクレインの製造法
US4504586A (en) * 1983-02-03 1985-03-12 Amgen Hybridoma tumor cell lines and their monoclonal antibodies to human colony stimulating factor subclass number 1
JPS6041615A (ja) * 1983-08-12 1985-03-05 Green Cross Corp:The コロニ−形成刺激因子の製造方法
US4658018A (en) * 1984-03-13 1987-04-14 Immunex Corporation Process for producing homogeneous colony stimulating factor
JPS61227526A (ja) * 1984-07-25 1986-10-09 Chugai Pharmaceut Co Ltd 新規なコロニー刺激因子
ATE80894T1 (de) * 1985-02-05 1992-10-15 Cetus Oncology Corp Reinigung des natuerlichen kolonie-stimulierenden faktors-1.
WO1986004607A1 (en) * 1985-02-05 1986-08-14 Cetus Corporation Recombinant colony stimulating factor-1
JPS629323A (ja) * 1985-07-08 1987-01-17 Seiko Epson Corp 液晶素子の駆動方法
WO1987003204A1 (en) * 1985-11-27 1987-06-04 Genetics Institute, Inc. Treatment of aids-type disease
EP0307402B1 (en) * 1986-05-06 1993-08-11 Genetics Institute, Inc. Production of m-csf
US4879227A (en) * 1986-05-06 1989-11-07 Genetics Institute, Inc. Production of a recombinant human colony stimulating factor
US4868119A (en) * 1986-12-11 1989-09-19 Genetics Institute, Inc. Hematopoietic growth factors
EP0249477A3 (en) * 1986-06-12 1988-01-20 Immunex Corporation Functional recombinant analog polypeptides devoid of hydrophobic amino acids
JP2583770B2 (ja) * 1986-09-17 1997-02-19 大塚製薬株式会社 遺伝子
US5171675A (en) * 1988-07-28 1992-12-15 Cerretti Douglas P Macrophage colony stimulating factor-γ

Also Published As

Publication number Publication date
JP2561255B2 (ja) 1996-12-04
IL77789A (en) 1992-03-29
AU5517386A (en) 1986-08-26
DK474686A (da) 1986-12-05
NO863952D0 (no) 1986-10-03
DE3689391T2 (de) 1994-06-30
DK474686D0 (da) 1986-10-03
AU626639B2 (en) 1992-08-06
FI864016A0 (fi) 1986-10-03
NO179109B (no) 1996-04-29
BG49941A3 (en) 1992-03-16
US5470569A (en) 1995-11-28
FI100972B (fi) 1998-03-31
AU5013090A (en) 1990-11-01
FI864016A (fi) 1986-10-03
DE3689391D1 (de) 1994-01-27
AU594045B2 (en) 1990-03-01
JP2553829B2 (ja) 1996-11-13
JPH07163391A (ja) 1995-06-27
DK172843B1 (da) 1999-08-09
JPS62501607A (ja) 1987-07-02
NO863952L (no) 1986-10-03
WO1986004607A1 (en) 1986-08-14
EP0209601A1 (en) 1987-01-28
EP0209601B1 (en) 1993-12-15

Similar Documents

Publication Publication Date Title
NO179109C (no) Ekspresjonsvektor, rekombinante vertsceller samt fremgangsmåte for fremstilling av terapeutisk aktivt, rekombinant CSF
FI94254B (fi) Menetelmä terapeuttisesti aktiivisten peptidijohdannaisten valmistamiseksi
AU6115886A (en) Improved virtual memory computer system
AU580023B2 (en) Fibrinolytically active hybrid protein
GB8508864D0 (en) Active polypeptide
GB2091268B (en) Recombinant dna-molecules and methods for protein production
IT1173866B (it) Metodo perfezionato per fabbricare dispositivi getter non evarobili porosi e dispositivi getter cosi' prodotti
NO175715C (no) Analogifremgangsmåte ved fremstilling av terapeutisk aktive aminosyrederivater, samt mellomprodukter ved fremstilling av disse
NO176920C (no) Enzymelektrode
DE3750106T2 (de) Rekombinanter B-Zell-Differenzierungsfaktor.
AU4751385A (en) DMA fragments, expression vectors, proteins, hosts, and process for production of the proteins
DK90985A (da) Fermenteringsstyreanlaeg
NO174970C (no) Rekombinant DNA, rekombinant DNA-vektor samt vertscelle
DK388789A (da) Hybridderivat af humant protein d, dets fremstilling og anvendelse samt dna, som koder derfor, og genstruktur og vaertscelle indeholdende denne dna
DE3650359T2 (de) Asynchrone reihen- und spaltensteuerung.
NO854405L (no) Fremgangsmaate for fremstilling av et antibiotisk aktivt polypeptid.
DK370085D0 (da) Antianafylaktisk virksomme farmaceutiske praeparater
AU589355B2 (en) Recombinant DNA expression vectors and method for gene expression
IT1213402B (it) Testa per bambola e metodo per lasua fabbricazione.
NO178036C (no) Fremgangsmåte for fremstilling av fusjonsproteiner, genstruktur, vektorer streptomycetceller og fusjonsproteinene
NO175434C (no) Rekombinant DNA-vektor, pattedyrcelle transformert med denne samt fremgangsmåte for fremstilling av human plasminogenaktivator
NO860278L (no) Betjeningselement for ladeanordning.
DK401786D0 (da) Substituerede cyclohexanalkansyrer samt fremgangsmaade til fremstilling deraf
EP0198014A4 (en) VECTORS CONTAINING A GENE FOR A PROTEIN HAVING ERYTHROID ACTIVATION ACTIVITY AND A RECOMBINANT DNA PROCESS FOR PRODUCING THE PROTEIN.
NO179453C (no) Fremgangsmåte for fremstilling av terapeutisk aktivt amphiregulin, vertscelle som produserer proteinet, rekombinant vektor inneholdt i vertscellen, samt nukleotidsekvens som koder for proteiner med amphiregulinaktivitet