DK388789A - Hybridderivat af humant protein d, dets fremstilling og anvendelse samt dna, som koder derfor, og genstruktur og vaertscelle indeholdende denne dna - Google Patents

Hybridderivat af humant protein d, dets fremstilling og anvendelse samt dna, som koder derfor, og genstruktur og vaertscelle indeholdende denne dna Download PDF

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Publication number
DK388789A
DK388789A DK388789A DK388789A DK388789A DK 388789 A DK388789 A DK 388789A DK 388789 A DK388789 A DK 388789A DK 388789 A DK388789 A DK 388789A DK 388789 A DK388789 A DK 388789A
Authority
DK
Denmark
Prior art keywords
humant
dna
coding
protein
production
Prior art date
Application number
DK388789A
Other languages
English (en)
Other versions
DK388789D0 (da
Inventor
Tamotsu Hashimoto
Mikiko Takahashi
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan filed Critical Hoechst Japan
Publication of DK388789D0 publication Critical patent/DK388789D0/da
Publication of DK388789A publication Critical patent/DK388789A/da

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Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14—Hydrolases (3)
    • C12N9/48—Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421—Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424—Serine endopeptidases (3.4.21)
    • C12N9/6464—Protein C (3.4.21.69)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Y—ENZYMES
    • C12Y304/00—Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21—Serine endopeptidases (3.4.21)
    • C12Y304/21069—Protein C activated (3.4.21.69)
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
DK388789A 1988-08-09 1989-08-08 Hybridderivat af humant protein d, dets fremstilling og anvendelse samt dna, som koder derfor, og genstruktur og vaertscelle indeholdende denne dna DK388789A (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63197144A JPH0246296A (ja) 1988-08-09 1988-08-09 雑種プロテインｃ及びその製造方法

Publications (2)

Publication Number Publication Date
DK388789D0 DK388789D0 (da) 1989-08-08
DK388789A true DK388789A (da) 1990-02-10

Family

ID=16369490

Family Applications (1)

Application Number Title Priority Date Filing Date
DK388789A DK388789A (da) 1988-08-09 1989-08-08 Hybridderivat af humant protein d, dets fremstilling og anvendelse samt dna, som koder derfor, og genstruktur og vaertscelle indeholdende denne dna

Country Status (9)

Country Link
EP (1) EP0354504A2 (da)
JP (1) JPH0246296A (da)
KR (1) KR900002795A (da)
AU (1) AU3937289A (da)
DK (1) DK388789A (da)
FI (1) FI893724A (da)
IL (1) IL91234A0 (da)
NO (1) NO893196L (da)
PT (1) PT91391A (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5358932A (en) * 1989-12-29 1994-10-25 Zymogenetics, Inc. Hybrid protein C
WO1991009960A1 (en) * 1989-12-29 1991-07-11 Zymogenetics, Inc. Hybrid protein c
JPH04127174U (ja) * 1991-05-09 1992-11-19 株式会社シマノ 釣り用リール
US5618714A (en) * 1993-12-15 1997-04-08 Eli Lilly And Company Methods for producing protein C
ES2265159T3 (es) * 1996-11-08 2007-02-01 Oklahoma Medical Research Foundation Uso de una proteina c modificada.
US6747003B1 (en) 1997-10-23 2004-06-08 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US6693075B1 (en) 1997-10-23 2004-02-17 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US6017882A (en) * 1997-10-23 2000-01-25 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US7247708B2 (en) 1997-10-23 2007-07-24 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US6998122B1 (en) 1999-04-30 2006-02-14 Eli Lilly And Company Protein C derivatives
CA2399267A1 (en) 2000-02-02 2001-08-09 Eli Lilly And Company Protein c derivatives
CA2397347C (en) 2000-02-11 2011-07-12 Maxygen Aps Factor vii or viia-like molecules
WO2001059084A1 (en) 2000-02-11 2001-08-16 Eli Lilly And Company Protein c derivatives
US7812132B2 (en) 2000-04-28 2010-10-12 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US7220837B1 (en) 2000-04-28 2007-05-22 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US20030211094A1 (en) 2001-06-26 2003-11-13 Nelsestuen Gary L. High molecular weight derivatives of vitamin k-dependent polypeptides
EP1370649A1 (en) * 2001-03-02 2003-12-17 T.A.C. Thrombosis and Coagulation AB Protein c variants
SI1499719T1 (sl) 2002-04-30 2011-03-31 Bayer Healthcare Llc Polipeptidne variante faktorja VII ali VIIa
AU2004221761B2 (en) 2003-03-20 2010-01-07 Bayer Healthcare Llc FVII or FVIIa variants
BRPI0411650A (pt) 2003-06-19 2006-08-08 Maxygen Holdings Ltd variante polipeptìdica do fator vii (fvii) ou do fator viia (fviia), sequencia de nucleotìdeos , vetor de expressão, célula hospedeira, composição, uso de uma variante, e, método para tratar de um mamìfero tendo uma doença ou um distúrbio em que a formação de coágulo seja desejável

Also Published As

Publication number Publication date
AU3937289A (en) 1990-04-12
FI893724A0 (fi) 1989-08-07
FI893724A (fi) 1990-02-10
PT91391A (pt) 1990-03-08
DK388789D0 (da) 1989-08-08
EP0354504A2 (en) 1990-02-14
IL91234A0 (en) 1990-03-19
NO893196D0 (no) 1989-08-08
JPH0246296A (ja) 1990-02-15
KR900002795A (ko) 1990-03-23
NO893196L (no) 1990-02-12

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