IL91234A0 - Hybrid protein c constructs and methods for their preparation - Google Patents

Hybrid protein c constructs and methods for their preparation

Info

Publication number
IL91234A0
IL91234A0 IL91234A IL9123489A IL91234A0 IL 91234 A0 IL91234 A0 IL 91234A0 IL 91234 A IL91234 A IL 91234A IL 9123489 A IL9123489 A IL 9123489A IL 91234 A0 IL91234 A0 IL 91234A0
Authority
IL
Israel
Prior art keywords
constructs
preparation
methods
hybrid protein
hybrid
Prior art date
Application number
IL91234A
Other languages
English (en)
Original Assignee
Hoechst Japan
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Japan filed Critical Hoechst Japan
Publication of IL91234A0 publication Critical patent/IL91234A0/xx

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/14Hydrolases (3)
    • C12N9/48Hydrolases (3) acting on peptide bonds (3.4)
    • C12N9/50Proteinases, e.g. Endopeptidases (3.4.21-3.4.25)
    • C12N9/64Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue
    • C12N9/6421Proteinases, e.g. Endopeptidases (3.4.21-3.4.25) derived from animal tissue from mammals
    • C12N9/6424Serine endopeptidases (3.4.21)
    • C12N9/6464Protein C (3.4.21.69)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12YENZYMES
    • C12Y304/00Hydrolases acting on peptide bonds, i.e. peptidases (3.4)
    • C12Y304/21Serine endopeptidases (3.4.21)
    • C12Y304/21069Protein C activated (3.4.21.69)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
IL91234A 1988-08-09 1989-08-07 Hybrid protein c constructs and methods for their preparation IL91234A0 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP63197144A JPH0246296A (ja) 1988-08-09 1988-08-09 雑種プロテインc及びその製造方法

Publications (1)

Publication Number Publication Date
IL91234A0 true IL91234A0 (en) 1990-03-19

Family

ID=16369490

Family Applications (1)

Application Number Title Priority Date Filing Date
IL91234A IL91234A0 (en) 1988-08-09 1989-08-07 Hybrid protein c constructs and methods for their preparation

Country Status (9)

Country Link
EP (1) EP0354504A2 (da)
JP (1) JPH0246296A (da)
KR (1) KR900002795A (da)
AU (1) AU3937289A (da)
DK (1) DK388789A (da)
FI (1) FI893724A (da)
IL (1) IL91234A0 (da)
NO (1) NO893196L (da)
PT (1) PT91391A (da)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69032029T2 (de) * 1989-12-29 1998-08-20 Zymogenetics Inc Hybrides protein c
US5358932A (en) * 1989-12-29 1994-10-25 Zymogenetics, Inc. Hybrid protein C
JPH04127174U (ja) * 1991-05-09 1992-11-19 株式会社シマノ 釣り用リール
US5618714A (en) * 1993-12-15 1997-04-08 Eli Lilly And Company Methods for producing protein C
WO1998020118A1 (en) * 1996-11-08 1998-05-14 Oklahoma Medical Research Foundation Modified protein c and methods of use thereof
US6747003B1 (en) 1997-10-23 2004-06-08 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US6693075B1 (en) 1997-10-23 2004-02-17 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US6017882A (en) * 1997-10-23 2000-01-25 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US7247708B2 (en) 1997-10-23 2007-07-24 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US6998122B1 (en) 1999-04-30 2006-02-14 Eli Lilly And Company Protein C derivatives
DE60108076T2 (de) 2000-02-02 2006-03-16 Eli Lilly And Co., Indianapolis Protein c derivate
EP1263943A1 (en) 2000-02-11 2002-12-11 Eli Lilly & Company Protein c derivatives
DE60138364D1 (de) 2000-02-11 2009-05-28 Bayer Healthcare Llc Gerinnungsfaktor vii oder viia konjugate
US7220837B1 (en) 2000-04-28 2007-05-22 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US7812132B2 (en) 2000-04-28 2010-10-12 Regents Of The University Of Minnesota Modified vitamin K-dependent polypeptides
US20030211094A1 (en) 2001-06-26 2003-11-13 Nelsestuen Gary L. High molecular weight derivatives of vitamin k-dependent polypeptides
EP1370649A1 (en) * 2001-03-02 2003-12-17 T.A.C. Thrombosis and Coagulation AB Protein c variants
NZ536340A (en) 2002-04-30 2006-09-29 Maxygen Holdings Ltd Factor VII or VIIa polypeptide variants with N-glycosylation
AU2004221761B2 (en) 2003-03-20 2010-01-07 Bayer Healthcare Llc FVII or FVIIa variants
PT1644504E (pt) 2003-06-19 2010-03-22 Bayer Healthcare Llc Variantes do domínio gla dos factores vii ou viia

Also Published As

Publication number Publication date
AU3937289A (en) 1990-04-12
NO893196L (no) 1990-02-12
DK388789D0 (da) 1989-08-08
EP0354504A2 (en) 1990-02-14
PT91391A (pt) 1990-03-08
NO893196D0 (no) 1989-08-08
FI893724A (fi) 1990-02-10
JPH0246296A (ja) 1990-02-15
DK388789A (da) 1990-02-10
KR900002795A (ko) 1990-03-23
FI893724A0 (fi) 1989-08-07

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