NO174748C - 9- av farmakologisk aktive pregnaner - Google Patents
9- av farmakologisk aktive pregnanerInfo
- Publication number
- NO174748C NO174748C NO882075A NO882075A NO174748C NO 174748 C NO174748 C NO 174748C NO 882075 A NO882075 A NO 882075A NO 882075 A NO882075 A NO 882075A NO 174748 C NO174748 C NO 174748C
- Authority
- NO
- Norway
- Prior art keywords
- pregnancies
- pharmacologically active
- pharmacologically
- active
- active pregnancies
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D235/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings
- C07D235/02—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, condensed with other rings condensed with carbocyclic rings or ring systems
- C07D235/04—Benzimidazoles; Hydrogenated benzimidazoles
- C07D235/24—Benzimidazoles; Hydrogenated benzimidazoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 2
- C07D235/28—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0014—Androstane derivatives substituted in position 17 alfa, not substituted in position 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
- C07J1/0003—Androstane derivatives
- C07J1/0033—Androstane derivatives substituted in position 17 alfa and 17 beta
- C07J1/004—Androstane derivatives substituted in position 17 alfa and 17 beta the substituent in position 17 alfa being an unsaturated hydrocarbon group
- C07J1/0048—Alkynyl derivatives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J13/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17
- C07J13/005—Normal steroids containing carbon, hydrogen, halogen or oxygen having a carbon-to-carbon double bond from or to position 17 with double bond in position 16 (17)
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J31/00—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring
- C07J31/006—Normal steroids containing one or more sulfur atoms not belonging to a hetero ring not covered by C07J31/003
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0038—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 with an androstane skeleton, including 18- or 19-substituted derivatives, 18-nor derivatives and also derivatives where position 17-beta is substituted by a carbon atom not directly bonded to a further carbon atom and not being part of an amide group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0094—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 containing nitrile radicals, including thiocyanide radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
- C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
- C07J5/0053—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/0045—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa not substituted in position 16
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
- C07J7/001—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group
- C07J7/004—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa
- C07J7/005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16
- C07J7/0055—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21 substituted in position 20 by a keto group substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/008—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21
- C07J7/0085—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms substituted in position 21 by an halogen atom
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
EP86201754 | 1986-10-10 | ||
EP87201340 | 1987-07-13 | ||
PCT/NL1987/000026 WO1988002753A2 (en) | 1986-10-10 | 1987-10-09 | 9-alpha-hydroxy steroids and process for their preparation |
Publications (4)
Publication Number | Publication Date |
---|---|
NO882075L NO882075L (no) | 1988-05-11 |
NO882075D0 NO882075D0 (no) | 1988-05-11 |
NO174748B NO174748B (no) | 1994-03-21 |
NO174748C true NO174748C (no) | 1994-06-29 |
Family
ID=26103306
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NO882075A NO174748C (no) | 1986-10-10 | 1988-05-11 | 9- av farmakologisk aktive pregnaner |
Country Status (19)
Country | Link |
---|---|
US (2) | US5352809A (no) |
EP (1) | EP0263569B1 (no) |
JP (1) | JPH0826062B2 (no) |
KR (1) | KR960010793B1 (no) |
CN (2) | CN1035182C (no) |
AU (1) | AU607948B2 (no) |
CA (1) | CA1334844C (no) |
DE (1) | DE3783007T2 (no) |
DK (1) | DK175438B1 (no) |
ES (1) | ES2052550T3 (no) |
FI (1) | FI95710C (no) |
GR (1) | GR3006576T3 (no) |
HU (2) | HU204063B (no) |
IE (1) | IE61985B1 (no) |
IL (1) | IL84135A (no) |
NO (1) | NO174748C (no) |
NZ (1) | NZ222103A (no) |
PT (1) | PT85891B (no) |
WO (1) | WO1988002753A2 (no) |
Families Citing this family (40)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AU607948B2 (en) * | 1986-10-10 | 1991-03-21 | Aventis Pharma S.A. | 9-alpha-hydroxy steroids and process for their preparation |
US4921638A (en) * | 1986-11-05 | 1990-05-01 | The Upjohn Company | 17β-cyano-9α,17α-dihydroxyandrost-4-en-3-one |
DE3876769T2 (de) * | 1987-12-23 | 1993-06-09 | Roussel Uclaf | Mikrobiologische herstellung von 9-alpha-hydroxy-17-keto-steroiden. |
US5298398A (en) * | 1987-12-23 | 1994-03-29 | Gist-Brocades Nv | Preparation of 9-α-hydroxy-17-keto steroids using Mycobacterium species CBS 482.86 |
US5372996A (en) * | 1989-03-10 | 1994-12-13 | Endorecherche, Inc. | Method of treatment of androgen-related diseases |
US5364847A (en) * | 1989-03-10 | 1994-11-15 | Endorecherche | Inhibitors of sex steroid biosynthesis and methods for their production and use |
EP0595796B1 (en) * | 1989-07-07 | 2003-01-15 | Endorecherche Inc. | Method of treatment of androgen-related diseases |
DE69032648T2 (de) * | 1989-07-07 | 1999-04-08 | Endorecherche Inc | Androgenderivate zur Hemming der Aktivität der Sexualsteroide |
ZA909444B (en) * | 1989-11-27 | 1991-08-28 | Schering Corp | Process for dehydrating corticosteroid intermediates |
JPH05501115A (ja) * | 1990-03-27 | 1993-03-04 | シェリング・コーポレーション | 9α―ヒドロキシ ステロイドの脱水法 |
US5124154A (en) * | 1990-06-12 | 1992-06-23 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
US5256408A (en) * | 1990-06-12 | 1993-10-26 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
US5209926A (en) * | 1990-06-12 | 1993-05-11 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
US5252319A (en) * | 1990-06-12 | 1993-10-12 | Insite Vision Incorporated | Aminosteroids for ophthalmic use |
EP0624162B1 (en) * | 1992-01-28 | 1998-09-16 | Schering Corporation | Novel steroid intermediates and processes for their preparation |
CZ286894A3 (en) * | 1992-05-21 | 1995-09-13 | Endorecherche Inc | Pharmaceutical preparation |
FR2692580B1 (fr) * | 1992-06-19 | 1994-08-26 | Roussel Uclaf | Nouveau Procédé de préparation d'un composé stéroïde DELTA9 (11). |
EP0759928A1 (en) * | 1994-05-09 | 1997-03-05 | The Upjohn Company | Synthesis of 17beta-cyano-3-ethoxy-17alpha-hydroxy-6-methylandrosta-3,5,9(11)-triene |
FR2720747B1 (fr) * | 1994-06-02 | 1996-07-12 | Roussel Uclaf | Nouveau procédé de préparation d'un stéroïde 16béta-méthyl et nouveaux intermédiaires. |
PT973791E (pt) | 1995-12-11 | 2007-09-26 | Searle Llc | Processo para a preparação de um composto epoxi |
KR100523409B1 (ko) | 1996-12-11 | 2005-10-24 | 지.디. 썰 엘엘씨 | 9,11-에폭시 스테로이드의 제조방법 및 이 제조방법에유용한 중간체 |
US6887991B1 (en) * | 1996-12-11 | 2005-05-03 | G. D. Searle & Company | Processes for preparation of 9, 11-epoxy steroids and intermediates useful therein |
US6610917B2 (en) * | 1998-05-15 | 2003-08-26 | Lester F. Ludwig | Activity indication, external source, and processing loop provisions for driven vibrating-element environments |
WO1999061055A1 (en) | 1998-05-22 | 1999-12-02 | The Board Of Trustees Of The Leland Stanford Junior University | Bifunctional molecules and therapies based thereon |
MXPA04009178A (es) * | 2002-03-22 | 2004-11-26 | Upjohn Co | Proceso para preparar eplerenona. |
US7235655B2 (en) | 2002-03-22 | 2007-06-26 | Pharmacia & Upjohn Company | Processes to prepare eplerenone |
EP2392258B1 (en) | 2005-04-28 | 2014-10-08 | Proteus Digital Health, Inc. | Pharma-informatics system |
US9062126B2 (en) | 2005-09-16 | 2015-06-23 | Raptor Pharmaceuticals Inc. | Compositions comprising receptor-associated protein (RAP) variants specific for CR-containing proteins and uses thereof |
DE102007027635A1 (de) * | 2007-06-12 | 2008-12-18 | Bayer Schering Pharma Aktiengesellschaft | 17ß-Cyano-19-androst-4-en-Derivat, dessen Verwendung und das Derivat enthaltende Arzneimittel |
TR201908314T4 (tr) | 2009-02-20 | 2019-06-21 | 2 Bbb Medicines B V | Glutatyon bazlı ilaç dağıtım sistemi. |
IL295075A (en) | 2009-05-06 | 2022-09-01 | Laboratory Skin Care Inc | Preparations for administration through the skin that include complexes of an active substance with calcium phosphate and methods of using them |
CN102516345B (zh) * | 2011-11-01 | 2014-11-26 | 上海优拓医药科技有限公司 | 醋酸乌利司他及其关键中间体的制备方法 |
EP2794632B1 (en) * | 2011-12-23 | 2016-03-16 | Crystal Pharma S.A.U | Process for alkynylating 16-substituted-17-keto steroids |
EP2948152A4 (en) * | 2013-01-23 | 2016-12-14 | Sphaera Pharma Private Ltd | NOVEL COMPOUNDS OF 11-BETA HYDROXY-STEROIDS FOR USE IN MITOCHONDRIA BIOGENESIS AND DISEASES RELATED TO MITOCHONDRIA DYSFUNCTION OR ADDITIONAL |
CN103361394B (zh) * | 2013-08-07 | 2016-08-17 | 中国科学院上海高等研究院 | 利用微生物转化制备9α-羟基-雄烯二酮的方法 |
JP6781148B2 (ja) | 2014-07-23 | 2020-11-04 | スファエラ ファーマ プライベート リミテッド | ヒドロキシステロイド化合物、それらの中間体、それらの調製方法、組成物および使用 |
CN105440094B (zh) * | 2015-11-27 | 2017-08-25 | 江苏佳尔科药业集团有限公司 | 地塞米松中间体的制备方法 |
CN109369759A (zh) * | 2018-11-22 | 2019-02-22 | 湖南原野医药有限公司 | 氢化可的松中间体17β-氰基甾体化合物的合成方法 |
CN109734762B (zh) * | 2018-12-05 | 2020-04-17 | 郑良彬 | 一锅法合成16-β甲基甾体化合物的方法 |
CN111320665A (zh) * | 2020-03-04 | 2020-06-23 | 台州仙琚药业有限公司 | 制备17β-氰基-17α-羟基-9-去氢雄烯二酮的方法 |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CA565369A (en) * | 1958-10-28 | P. Graber Robert | 9,11-dihydroxy steroids and processes for preparing the same | |
US2837545A (en) * | 1957-04-29 | 1958-06-03 | American Cyanamid Co | 9alpha, 11beta, 16alpha, 17alpha, 21-penta-hydroxy-4-pregnene-3, 20 dione, its 16, 21 diesters and process of preparing the above compounds |
US2840580A (en) * | 1957-05-24 | 1958-06-24 | Olin Mathieson | 9alpha-hydroxy steroids |
US4035236A (en) * | 1975-10-24 | 1977-07-12 | The Upjohn Company | Process for preparing 9α-hydroxyandrostenedione |
US4102907A (en) * | 1977-03-07 | 1978-07-25 | The Upjohn Company | Desulfinylation process for preparing androsta-4,9(11)-diene-3,17-dione |
US4397947A (en) * | 1981-06-12 | 1983-08-09 | G. D. Searle & Co. | Microbial process for 9α-hydroxylation of steroids |
US4383947A (en) * | 1981-07-24 | 1983-05-17 | The Upjohn Company | Introduction of a fluorine atom |
US4416821A (en) * | 1982-02-17 | 1983-11-22 | The Upjohn Company | Process for preparing 16-methylene steroids |
US4618456A (en) * | 1984-03-20 | 1986-10-21 | The Upjohn Company | Ethynylation of 16-methyl-17-keto steroids |
EP0153001B1 (en) * | 1984-02-03 | 1992-03-11 | The Upjohn Company | Steroids having an enamide or enimide group and their preparation |
US4705783A (en) * | 1985-06-25 | 1987-11-10 | Sri International | 9α, 11β-substituted and 11β-substituted estranes |
AU607948B2 (en) * | 1986-10-10 | 1991-03-21 | Aventis Pharma S.A. | 9-alpha-hydroxy steroids and process for their preparation |
US4921638A (en) * | 1986-11-05 | 1990-05-01 | The Upjohn Company | 17β-cyano-9α,17α-dihydroxyandrost-4-en-3-one |
-
1987
- 1987-10-09 AU AU81068/87A patent/AU607948B2/en not_active Expired
- 1987-10-09 PT PT85891A patent/PT85891B/pt unknown
- 1987-10-09 IL IL84135A patent/IL84135A/xx not_active IP Right Cessation
- 1987-10-09 HU HU875312A patent/HU204063B/hu unknown
- 1987-10-09 KR KR1019880700547A patent/KR960010793B1/ko not_active IP Right Cessation
- 1987-10-09 JP JP62506679A patent/JPH0826062B2/ja not_active Expired - Lifetime
- 1987-10-09 WO PCT/NL1987/000026 patent/WO1988002753A2/en active IP Right Grant
- 1987-10-09 EP EP87201933A patent/EP0263569B1/en not_active Expired - Lifetime
- 1987-10-09 NZ NZ222103A patent/NZ222103A/xx unknown
- 1987-10-09 DE DE8787201933T patent/DE3783007T2/de not_active Expired - Lifetime
- 1987-10-09 ES ES87201933T patent/ES2052550T3/es not_active Expired - Lifetime
- 1987-10-09 US US07/412,557 patent/US5352809A/en not_active Expired - Lifetime
- 1987-10-10 CN CN87106868A patent/CN1035182C/zh not_active Expired - Lifetime
- 1987-10-12 IE IE272287A patent/IE61985B1/en not_active IP Right Cessation
- 1987-10-13 CA CA000549165A patent/CA1334844C/en not_active Expired - Lifetime
-
1988
- 1988-05-11 NO NO882075A patent/NO174748C/no unknown
- 1988-05-25 FI FI882461A patent/FI95710C/fi not_active IP Right Cessation
- 1988-06-09 DK DK198803131A patent/DK175438B1/da not_active IP Right Cessation
-
1991
- 1991-07-18 HU HU912420A patent/HU211080B/hu unknown
-
1992
- 1992-12-18 GR GR920402131T patent/GR3006576T3/el unknown
-
1994
- 1994-10-04 US US08/317,960 patent/US5565588A/en not_active Expired - Lifetime
-
1995
- 1995-05-11 CN CN95105415A patent/CN1036342C/zh not_active Expired - Lifetime
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