NO165799C - Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-substituerte 2-oksindol-1-karboksamider og mellomprodukter for anvendelse ved fremgansmaaten. - Google Patents

Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-substituerte 2-oksindol-1-karboksamider og mellomprodukter for anvendelse ved fremgansmaaten.

Info

Publication number
NO165799C
NO165799C NO851054A NO851054A NO165799C NO 165799 C NO165799 C NO 165799C NO 851054 A NO851054 A NO 851054A NO 851054 A NO851054 A NO 851054A NO 165799 C NO165799 C NO 165799C
Authority
NO
Norway
Prior art keywords
intermediates
carboxamides
preparation
alkyl
optionally substituted
Prior art date
Application number
NO851054A
Other languages
English (en)
Norwegian (no)
Other versions
NO165799B (no
NO851054L (no
Inventor
Saul Bernard Kadin
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of NO851054L publication Critical patent/NO851054L/no
Publication of NO165799B publication Critical patent/NO165799B/no
Publication of NO165799C publication Critical patent/NO165799C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/32—Oxygen atoms
    • C07D209/34—Oxygen atoms in position 2
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
    • C07D413/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Rheumatology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicinal Preparation (AREA)
NO851054A 1984-03-19 1985-03-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-substituerte 2-oksindol-1-karboksamider og mellomprodukter for anvendelse ved fremgansmaaten. NO165799C (no)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US59065984A 1984-03-19 1984-03-19
US06/684,634 US4556672A (en) 1984-03-19 1984-12-21 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents

Publications (3)

Publication Number Publication Date
NO851054L NO851054L (no) 1985-09-20
NO165799B NO165799B (no) 1991-01-02
NO165799C true NO165799C (no) 1991-04-10

Family

ID=27080909

Family Applications (1)

Application Number Title Priority Date Filing Date
NO851054A NO165799C (no) 1984-03-19 1985-03-18 Analogifremgangsmaate for fremstilling av terapeutisk aktive 3-substituerte 2-oksindol-1-karboksamider og mellomprodukter for anvendelse ved fremgansmaaten.

Country Status (36)

Country Link
US (1) US4556672A (fr)
EP (1) EP0156603B1 (fr)
JP (1) JPH04235165A (fr)
KR (1) KR860001873B1 (fr)
AT (1) ATE45731T1 (fr)
AU (1) AU549927B2 (fr)
BG (1) BG60347B2 (fr)
CA (2) CA1251441A (fr)
CS (1) CS249539B2 (fr)
CY (1) CY1668A (fr)
DE (1) DE3572481D1 (fr)
DK (1) DK162090C (fr)
EG (1) EG17795A (fr)
ES (1) ES541372A0 (fr)
FI (2) FI82042C (fr)
GR (1) GR850668B (fr)
HK (1) HK78392A (fr)
HU (1) HU196178B (fr)
IE (1) IE57743B1 (fr)
IL (3) IL74631A (fr)
LV (1) LV5618A3 (fr)
MA (1) MA20380A1 (fr)
MY (1) MY101987A (fr)
NL (1) NL940025I2 (fr)
NO (1) NO165799C (fr)
NZ (2) NZ224134A (fr)
OA (1) OA07966A (fr)
PH (2) PH21323A (fr)
PL (1) PL145951B1 (fr)
PT (1) PT80117B (fr)
RO (1) RO90952B (fr)
SI (1) SI8510440A8 (fr)
SU (1) SU1445556A3 (fr)
UA (1) UA6343A1 (fr)
YU (1) YU43870B (fr)
ZW (1) ZW4785A1 (fr)

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Also Published As

Publication number Publication date
FI82449B (fi) 1990-11-30
LV5618A3 (lv) 1994-05-10
KR850006173A (ko) 1985-10-02
YU44085A (en) 1988-02-29
PH21323A (en) 1987-09-28
FI894540A (fi) 1989-09-26
JPH0561269B2 (fr) 1993-09-06
NL940025I2 (nl) 2000-01-03
GR850668B (fr) 1985-07-16
BG60347B2 (bg) 1994-09-30
MA20380A1 (fr) 1985-10-01
DK121385D0 (da) 1985-03-18
ATE45731T1 (de) 1989-09-15
IL74631A0 (en) 1985-06-30
IE850684L (en) 1985-09-19
IL85130A0 (en) 1988-06-30
ZW4785A1 (en) 1985-06-19
EP0156603A3 (en) 1986-02-12
DK162090C (da) 1992-02-24
ES8603408A1 (es) 1985-12-16
HU196178B (en) 1988-10-28
EP0156603A2 (fr) 1985-10-02
FI851069L (fi) 1985-09-20
AU549927B2 (en) 1986-02-20
PL252434A1 (en) 1985-12-03
IL74631A (en) 1988-07-31
YU43870B (en) 1989-12-31
SU1445556A3 (ru) 1988-12-15
CS249539B2 (en) 1987-03-12
FI851069A0 (fi) 1985-03-18
IL85130A (en) 1988-07-31
NO165799B (no) 1991-01-02
NL940025I1 (nl) 1995-02-01
EP0156603B1 (fr) 1989-08-23
NZ224134A (en) 1988-10-28
AU4005985A (en) 1985-09-26
IE57743B1 (en) 1993-03-24
FI894540A0 (fi) 1989-09-26
FI82042C (fi) 1991-01-10
CY1668A (en) 1993-05-14
RO90952A (fr) 1987-02-27
PT80117B (pt) 1987-10-20
NZ211486A (en) 1988-10-28
CA1288422C (fr) 1991-09-03
PH21470A (en) 1987-10-28
US4556672A (en) 1985-12-03
DK121385A (da) 1985-09-20
HK78392A (en) 1992-10-23
SI8510440A8 (sl) 1996-06-30
CA1251441A (fr) 1989-03-21
NO851054L (no) 1985-09-20
RO90952B (ro) 1987-03-01
PT80117A (en) 1985-04-01
ES541372A0 (es) 1985-12-16
FI82042B (fi) 1990-09-28
MY101987A (en) 1992-02-29
DE3572481D1 (en) 1989-09-28
PL145951B1 (en) 1988-12-31
EG17795A (en) 1990-08-30
JPH04235165A (ja) 1992-08-24
DK162090B (da) 1991-09-16
OA07966A (fr) 1987-01-31
FI82449C (fi) 1991-03-11
KR860001873B1 (ko) 1986-10-24
HUT37398A (en) 1985-12-28
UA6343A1 (uk) 1994-12-29

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