ATE145206T1 - Oxindol 1-(n-(alkoxycarbonyl)>carboxamide und 1- (n-carboxamido>carboxamide als antiinflammatorische wirkstoffe - Google Patents
Oxindol 1-(n-(alkoxycarbonyl)>carboxamide und 1- (n-carboxamido>carboxamide als antiinflammatorische wirkstoffeInfo
- Publication number
- ATE145206T1 ATE145206T1 AT94903461T AT94903461T ATE145206T1 AT E145206 T1 ATE145206 T1 AT E145206T1 AT 94903461 T AT94903461 T AT 94903461T AT 94903461 T AT94903461 T AT 94903461T AT E145206 T1 ATE145206 T1 AT E145206T1
- Authority
- AT
- Austria
- Prior art keywords
- carboxamide
- pct
- oxindol
- carboxamido
- alkoxycarbonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1511493A | 1993-02-09 | 1993-02-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE145206T1 true ATE145206T1 (de) | 1996-11-15 |
Family
ID=21769613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT94903461T ATE145206T1 (de) | 1993-02-09 | 1993-12-10 | Oxindol 1-(n-(alkoxycarbonyl)>carboxamide und 1- (n-carboxamido>carboxamide als antiinflammatorische wirkstoffe |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5607959A (de) |
| EP (1) | EP0683777B1 (de) |
| JP (1) | JP2709530B2 (de) |
| AT (1) | ATE145206T1 (de) |
| CA (1) | CA2155664C (de) |
| DE (1) | DE69305999T2 (de) |
| DK (1) | DK0683777T3 (de) |
| ES (1) | ES2097025T3 (de) |
| FI (1) | FI940568A7 (de) |
| GR (1) | GR3021924T3 (de) |
| WO (1) | WO1994018194A1 (de) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997013767A1 (de) * | 1995-10-09 | 1997-04-17 | Chemisch Pharmazeutische Forschungsgesellschaft Mbh | Heterocyclisch substituierte 1-indolcarboxamide als cyclooxygenase-2 inhibitoren |
| EP1175399B1 (de) * | 1999-04-23 | 2009-03-11 | Vertex Pharmaceuticals Incorporated | Inhibitoren von c-jun n-terminal kinasen (jnk) |
| US7612065B2 (en) | 2000-04-21 | 2009-11-03 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-JUN N-terminal kinases (JNK) |
| AU2002322720B2 (en) | 2001-07-25 | 2008-11-13 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| CN102379684B (zh) | 2005-04-28 | 2014-11-19 | 普罗透斯数字保健公司 | 药物信息系统 |
| KR20090071598A (ko) | 2006-09-18 | 2009-07-01 | 랩터 파마슈티컬 인코포레이티드 | 수용체 결합 단백질(ｒａｐ)-접합체 투여에 의한 간 질환의 치료 |
| EP2398500B1 (de) | 2009-02-20 | 2019-03-13 | 2-BBB Medicines B.V. | Arzneiabgabesystem auf glutathion-basis |
| ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE63543T1 (de) * | 1984-02-07 | 1991-06-15 | Pfizer | 2-oxindolzwischenprodukte. |
| US4721712A (en) * | 1984-06-12 | 1988-01-26 | Pfizer Inc. | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| IN163263B (de) * | 1984-02-07 | 1988-08-27 | Pfizer | |
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
| US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
| MX18021A (es) * | 1988-10-18 | 1993-11-01 | Pfizer | Pro-farmacos de la 3-acil-2-oxindol-1-carboxamidasanti-inflamatorias |
| ES2075055T3 (es) * | 1988-10-18 | 1995-10-01 | Pfizer | Profarmacos de 3-acil-2-oxindol-1-carboxamidas antiinflamatorias. |
| US5047554A (en) * | 1989-04-18 | 1991-09-10 | Pfizer Inc. | 3-substituted-2-oxindole derivatives |
| US4952703A (en) * | 1989-05-25 | 1990-08-28 | Pfizer Inc. | Intermediates for making 2-oxindole-1-carboxamides |
| US5270331A (en) * | 1993-01-26 | 1993-12-14 | Pfizer, Inc. | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides |
-
1993
- 1993-12-10 WO PCT/US1993/011792 patent/WO1994018194A1/en not_active Ceased
- 1993-12-10 DE DE69305999T patent/DE69305999T2/de not_active Expired - Fee Related
- 1993-12-10 EP EP94903461A patent/EP0683777B1/de not_active Expired - Lifetime
- 1993-12-10 DK DK94903461.5T patent/DK0683777T3/da active
- 1993-12-10 JP JP6518013A patent/JP2709530B2/ja not_active Expired - Fee Related
- 1993-12-10 AT AT94903461T patent/ATE145206T1/de not_active IP Right Cessation
- 1993-12-10 US US08/495,509 patent/US5607959A/en not_active Expired - Fee Related
- 1993-12-10 ES ES94903461T patent/ES2097025T3/es not_active Expired - Lifetime
- 1993-12-10 CA CA002155664A patent/CA2155664C/en not_active Expired - Fee Related
-
1994
- 1994-02-08 FI FI940568A patent/FI940568A7/fi not_active Application Discontinuation
-
1996
- 1996-12-06 GR GR960403329T patent/GR3021924T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0683777B1 (de) | 1996-11-13 |
| JPH08502517A (ja) | 1996-03-19 |
| US5607959A (en) | 1997-03-04 |
| GR3021924T3 (en) | 1997-03-31 |
| FI940568L (fi) | 1994-08-10 |
| DE69305999D1 (en) | 1996-12-19 |
| DK0683777T3 (da) | 1997-04-28 |
| WO1994018194A1 (en) | 1994-08-18 |
| CA2155664C (en) | 1999-06-15 |
| JP2709530B2 (ja) | 1998-02-04 |
| DE69305999T2 (de) | 1997-03-06 |
| CA2155664A1 (en) | 1994-08-18 |
| ES2097025T3 (es) | 1997-03-16 |
| FI940568A0 (fi) | 1994-02-08 |
| EP0683777A1 (de) | 1995-11-29 |
| FI940568A7 (fi) | 1994-08-10 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |