DK0683777T3 - Oxindol-1-N-(alkoxycarbonyl)carboxamider og -1-(N-carboxamido)carboxamider som antiinflammatoriske midler - Google Patents
Oxindol-1-N-(alkoxycarbonyl)carboxamider og -1-(N-carboxamido)carboxamider som antiinflammatoriske midlerInfo
- Publication number
- DK0683777T3 DK0683777T3 DK94903461.5T DK94903461T DK0683777T3 DK 0683777 T3 DK0683777 T3 DK 0683777T3 DK 94903461 T DK94903461 T DK 94903461T DK 0683777 T3 DK0683777 T3 DK 0683777T3
- Authority
- DK
- Denmark
- Prior art keywords
- carboxamides
- pct
- oxindole
- carboxamido
- alkoxycarbonyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/06—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/06—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US1511493A | 1993-02-09 | 1993-02-09 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0683777T3 true DK0683777T3 (da) | 1997-04-28 |
Family
ID=21769613
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK94903461.5T DK0683777T3 (da) | 1993-02-09 | 1993-12-10 | Oxindol-1-N-(alkoxycarbonyl)carboxamider og -1-(N-carboxamido)carboxamider som antiinflammatoriske midler |
Country Status (11)
| Country | Link |
|---|---|
| US (1) | US5607959A (da) |
| EP (1) | EP0683777B1 (da) |
| JP (1) | JP2709530B2 (da) |
| AT (1) | ATE145206T1 (da) |
| CA (1) | CA2155664C (da) |
| DE (1) | DE69305999T2 (da) |
| DK (1) | DK0683777T3 (da) |
| ES (1) | ES2097025T3 (da) |
| FI (1) | FI940568A (da) |
| GR (1) | GR3021924T3 (da) |
| WO (1) | WO1994018194A1 (da) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1997013767A1 (de) * | 1995-10-09 | 1997-04-17 | Chemisch Pharmazeutische Forschungsgesellschaft Mbh | Heterocyclisch substituierte 1-indolcarboxamide als cyclooxygenase-2 inhibitoren |
| ATE425142T1 (de) * | 1999-04-23 | 2009-03-15 | Vertex Pharma | Inhibitoren von c-jun n-terminal kinasen (jnk) |
| US7612065B2 (en) | 2000-04-21 | 2009-11-03 | Vertex Pharmaceuticals Incorporated | Inhibitors of c-JUN N-terminal kinases (JNK) |
| EP1554572B1 (en) | 2001-07-25 | 2009-10-14 | Raptor Pharmaceutical Inc. | Compositions and methods for modulating blood-brain barrier transport |
| EP3827747A1 (en) | 2005-04-28 | 2021-06-02 | Otsuka Pharmaceutical Co., Ltd. | Pharma-informatics system |
| EP2063905B1 (en) | 2006-09-18 | 2014-07-30 | Raptor Pharmaceutical Inc | Treatment of liver disorders by administration of receptor-associated protein (rap)-conjugates |
| NZ616673A (en) | 2009-02-20 | 2014-08-29 | To Bbb Holding B V | Glutathione-based drug delivery system |
| ES2942923T3 (es) | 2009-05-06 | 2023-06-07 | Laboratory Skin Care Inc | Composiciones de administración dérmica que comprenden complejos de agente activo-partículas de fosfato de calcio y métodos de uso de las mismas |
| US20120077778A1 (en) | 2010-09-29 | 2012-03-29 | Andrea Bourdelais | Ladder-Frame Polyether Conjugates |
Family Cites Families (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IN163263B (da) * | 1984-02-07 | 1988-08-27 | Pfizer | |
| US4721712A (en) * | 1984-06-12 | 1988-01-26 | Pfizer Inc. | 1,3-disubstituted 2-oxindoles as analgesic and anti-inflammatory agents |
| DE3582890D1 (de) * | 1984-02-07 | 1991-06-20 | Pfizer | 2-oxindolzwischenprodukte. |
| US4556672A (en) * | 1984-03-19 | 1985-12-03 | Pfizer Inc. | 3-Substituted 2-oxindole-1-carboxamides as analgesic and anti-inflammatory agents |
| US4569942A (en) * | 1984-05-04 | 1986-02-11 | Pfizer Inc. | N,3-Disubstituted 2-oxindole-1-carboxamides as analgesic and antiinflammatory agents |
| DE68923673T2 (de) * | 1988-10-18 | 1996-01-18 | Pfizer | Prodrogen von antiinflammatorischen 3-Acyl-2-oxindol-1-carboxamiden. |
| HU208421B (en) * | 1988-10-18 | 1993-10-28 | Pfizer | Process for producing starting materials for producing 3-acyl-2-oxindol-carboxamides ofantiphlogistic activity |
| US5047554A (en) * | 1989-04-18 | 1991-09-10 | Pfizer Inc. | 3-substituted-2-oxindole derivatives |
| US4952703A (en) * | 1989-05-25 | 1990-08-28 | Pfizer Inc. | Intermediates for making 2-oxindole-1-carboxamides |
| US5270331A (en) * | 1993-01-26 | 1993-12-14 | Pfizer, Inc. | Prodrugs of antiinflammatory 3-acyl-2-oxindole-1-carboxamides |
-
1993
- 1993-12-10 CA CA002155664A patent/CA2155664C/en not_active Expired - Fee Related
- 1993-12-10 US US08/495,509 patent/US5607959A/en not_active Expired - Fee Related
- 1993-12-10 JP JP6518013A patent/JP2709530B2/ja not_active Expired - Fee Related
- 1993-12-10 ES ES94903461T patent/ES2097025T3/es not_active Expired - Lifetime
- 1993-12-10 WO PCT/US1993/011792 patent/WO1994018194A1/en active IP Right Grant
- 1993-12-10 DK DK94903461.5T patent/DK0683777T3/da active
- 1993-12-10 AT AT94903461T patent/ATE145206T1/de not_active IP Right Cessation
- 1993-12-10 DE DE69305999T patent/DE69305999T2/de not_active Expired - Fee Related
- 1993-12-10 EP EP94903461A patent/EP0683777B1/en not_active Expired - Lifetime
-
1994
- 1994-02-08 FI FI940568A patent/FI940568A/fi not_active Application Discontinuation
-
1996
- 1996-12-06 GR GR960403329T patent/GR3021924T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| EP0683777B1 (en) | 1996-11-13 |
| GR3021924T3 (en) | 1997-03-31 |
| US5607959A (en) | 1997-03-04 |
| ES2097025T3 (es) | 1997-03-16 |
| CA2155664C (en) | 1999-06-15 |
| ATE145206T1 (de) | 1996-11-15 |
| FI940568A (fi) | 1994-08-10 |
| FI940568A0 (fi) | 1994-02-08 |
| JP2709530B2 (ja) | 1998-02-04 |
| EP0683777A1 (en) | 1995-11-29 |
| WO1994018194A1 (en) | 1994-08-18 |
| DE69305999D1 (en) | 1996-12-19 |
| DE69305999T2 (de) | 1997-03-06 |
| JPH08502517A (ja) | 1996-03-19 |
| CA2155664A1 (en) | 1994-08-18 |
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