NO151895C - Fremgangsmaate for fremstilling av pyrido-indolderivater - Google Patents
Fremgangsmaate for fremstilling av pyrido-indolderivaterInfo
- Publication number
- NO151895C NO151895C NO794317A NO794317A NO151895C NO 151895 C NO151895 C NO 151895C NO 794317 A NO794317 A NO 794317A NO 794317 A NO794317 A NO 794317A NO 151895 C NO151895 C NO 151895C
- Authority
- NO
- Norway
- Prior art keywords
- indold
- pyrido
- derivatives
- procedure
- preparation
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/26—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D307/30—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/32—Oxygen atoms
- C07D307/33—Oxygen atoms in position 2, the oxygen atom being in its keto or unsubstituted enol form
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/09—Preparation of carboxylic acids or their salts, halides or anhydrides from carboxylic acid esters or lactones
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/42—Separation; Purification; Stabilisation; Use of additives
- C07C51/487—Separation; Purification; Stabilisation; Use of additives by treatment giving rise to chemical modification
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
- C07D307/02—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings
- C07D307/04—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members
- C07D307/18—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom not condensed with other rings having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D307/20—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Veterinary Medicine (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Anesthesiology (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Furan Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/005,698 US4224329A (en) | 1979-01-23 | 1979-01-23 | 2-Substituted-trans-5-aryl-2,3,4,4a,5,9b-hexahydro-1H-pyrido[4,3-b]indoles |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NO794317L NO794317L (no) | 1980-07-24 |
| NO151895B NO151895B (no) | 1985-03-18 |
| NO151895C true NO151895C (no) | 1985-06-26 |
Family
ID=21717248
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO794317A NO151895C (no) | 1979-01-23 | 1979-12-28 | Fremgangsmaate for fremstilling av pyrido-indolderivater |
| NO843041A NO843041L (no) | 1979-01-23 | 1984-07-27 | Nye 5-(fluorfenyl)-2-hydroksytetra-hydrofuraner |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NO843041A NO843041L (no) | 1979-01-23 | 1984-07-27 | Nye 5-(fluorfenyl)-2-hydroksytetra-hydrofuraner |
Country Status (34)
| Country | Link |
|---|---|
| US (1) | US4224329A (de) |
| JP (4) | JPS55100386A (de) |
| KR (1) | KR830001932A (de) |
| AR (1) | AR231291A1 (de) |
| AT (1) | AT376674B (de) |
| AU (1) | AU521986B2 (de) |
| BE (1) | BE881283A (de) |
| CA (1) | CA1144168A (de) |
| CH (2) | CH651040A5 (de) |
| CS (4) | CS221808B2 (de) |
| DD (2) | DD149071A5 (de) |
| DE (1) | DE3002367A1 (de) |
| DK (1) | DK25580A (de) |
| EG (1) | EG14767A (de) |
| FI (1) | FI800179A (de) |
| FR (3) | FR2447379A1 (de) |
| GB (1) | GB2041925B (de) |
| GR (1) | GR73567B (de) |
| HU (3) | HU189174B (de) |
| IE (1) | IE49500B1 (de) |
| IL (1) | IL59189A (de) |
| IN (1) | IN153300B (de) |
| IT (1) | IT1149927B (de) |
| LU (1) | LU82105A1 (de) |
| NL (1) | NL8000385A (de) |
| NO (2) | NO151895C (de) |
| NZ (3) | NZ192175A (de) |
| PH (4) | PH15736A (de) |
| PL (4) | PL126032B1 (de) |
| PT (1) | PT70724A (de) |
| SE (3) | SE441358B (de) |
| SU (3) | SU1168094A3 (de) |
| YU (2) | YU269379A (de) |
| ZA (1) | ZA796374B (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4431649A (en) * | 1979-07-30 | 1984-02-14 | Pfizer Inc. | Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents |
| US4431646A (en) * | 1979-07-30 | 1984-02-14 | Pfizer Inc. | Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents |
| US4432978A (en) * | 1979-07-30 | 1984-02-21 | Pfizer Inc. | Hexahydro-trans-pyridoindole |
| US4337250A (en) * | 1979-07-30 | 1982-06-29 | Pfizer Inc. | Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents |
| US4427679A (en) | 1981-01-16 | 1984-01-24 | Pfizer Inc. | Hexahydro-trans- and tetrahydropyridoindole neuroleptic agents |
| US4467090A (en) * | 1982-09-30 | 1984-08-21 | Pfizer Inc. | Compound, 8-fluoro-5-(p-fluorophenyl)-2-[4-(p-fluorophenyl)-4-hydroxybutyryl]-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole |
| US4477669A (en) * | 1982-09-30 | 1984-10-16 | Pfizer Inc. | Processes and intermediates useful in the preparation of flutroline |
| US4451655A (en) * | 1982-05-17 | 1984-05-29 | Pfizer Inc. | Process for preparing carboline derivatives and compounds used in their preparation |
| US4698444A (en) * | 1982-09-30 | 1987-10-06 | Pfizer Inc. | 1,1-bis(p-fluorophenyl)urea |
| US4568748A (en) * | 1982-09-30 | 1986-02-04 | Pfizer Inc. | 2-Carbobenzoxy-8-fluoro-5-(p-fluorophenyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole |
| JPS61248502A (ja) * | 1985-04-26 | 1986-11-05 | Pioneer Electronic Corp | 磁性材料の接合方法 |
| US4672117A (en) * | 1985-09-16 | 1987-06-09 | American Home Products Corporation | Antipsychotic gamma-carbolines |
| US4636563A (en) * | 1985-09-16 | 1987-01-13 | American Home Products Corporation | Antipsychotic γ-carbolines |
| US4798896A (en) * | 1988-01-19 | 1989-01-17 | American Home Products Corporation | Antipsychotic gamma-carboline N-oxides |
| US5075315A (en) * | 1990-05-17 | 1991-12-24 | Mcneilab, Inc. | Antipsychotic hexahydro-2H-indeno[1,2-c]pyridine derivatives |
| CA2355716C (en) * | 1998-12-21 | 2010-05-18 | Janssen Pharmaceutica N.V. | Benzisoxazoles and phenones as .alpha.2-antagonists |
| RU2329044C1 (ru) * | 2006-11-16 | 2008-07-20 | Андрей Александрович Иващенко | Лиганды 5-ht6 рецепторов, фармацевтическая композиция, способ ее получения и лекарственное средство |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA551241A (en) * | 1958-01-07 | S. Abbott Leslie | Production of substituted piperidines | |
| US3382250A (en) * | 1966-12-07 | 1968-05-07 | Abbott Lab | Aroylalkyl derivatives of 1, 2, 3, 4-tetrahydro-5h-pyrido[4, 3b]indoles |
| US3687961A (en) * | 1971-05-03 | 1972-08-29 | Abbott Lab | 8-fluoro-2-{8 3-(4-fluorophenylanilinopropyl{9 -gamma-carboline |
| AR205452A1 (es) * | 1973-12-06 | 1976-05-07 | Endo Lab | Metodo para preparar nuevos trans-2, 3, 4, 4a, 5, 9b-hexahidro-5-fenil-1h-pirido(4,3-b) indoles |
| JPS50126699A (de) * | 1974-03-20 | 1975-10-04 | ||
| AR206812A1 (es) * | 1974-04-01 | 1976-08-23 | Pfizer | Compuestos intermediarios de azaciclo(3,4-a)indoles 4- y 5-fenil substituidos desprovistos de actividad terapeutica |
| US4001263A (en) * | 1974-04-01 | 1977-01-04 | Pfizer Inc. | 5-Aryl-1,2,3,4-tetrahydro-γ-carbolines |
| SE7702301L (sv) * | 1976-04-08 | 1977-10-09 | Endo Lab | Trans-hexahydro-pyrido-indoler |
| SE441448B (sv) * | 1977-05-23 | 1985-10-07 | Pfizer | Sett att framstella hexahydro-gamma-karbolinforeningar |
-
1979
- 1979-01-23 US US06/005,698 patent/US4224329A/en not_active Expired - Lifetime
- 1979-10-17 IN IN726/DEL/79A patent/IN153300B/en unknown
- 1979-10-22 PH PH23203A patent/PH15736A/en unknown
- 1979-11-05 YU YU02693/79A patent/YU269379A/xx unknown
- 1979-11-19 EG EG668/79D patent/EG14767A/xx active
- 1979-11-20 NZ NZ192175A patent/NZ192175A/en unknown
- 1979-11-20 NZ NZ197581A patent/NZ197581A/en unknown
- 1979-11-20 NZ NZ197582A patent/NZ197582A/en unknown
- 1979-11-20 AR AR278965A patent/AR231291A1/es active
- 1979-11-23 ZA ZA00796374A patent/ZA796374B/xx unknown
- 1979-12-28 NO NO794317A patent/NO151895C/no unknown
-
1980
- 1980-01-03 CS CS815711A patent/CS221808B2/cs unknown
- 1980-01-03 CS CS8098A patent/CS221806B2/cs unknown
- 1980-01-03 CS CS815710A patent/CS221807B2/cs unknown
- 1980-01-03 CS CS815712A patent/CS221809B2/cs unknown
- 1980-01-04 HU HU822858A patent/HU189174B/hu unknown
- 1980-01-04 HU HU8023A patent/HU184712B/hu unknown
- 1980-01-04 SU SU802865803A patent/SU1168094A3/ru active
- 1980-01-04 HU HU822859A patent/HU188201B/hu unknown
- 1980-01-07 PL PL1980231005A patent/PL126032B1/pl unknown
- 1980-01-07 PL PL1980231006A patent/PL126532B1/pl unknown
- 1980-01-07 PL PL1980221248A patent/PL120774B1/pl unknown
- 1980-01-07 PL PL1980231004A patent/PL126867B1/pl unknown
- 1980-01-15 SE SE8000329A patent/SE441358B/sv unknown
- 1980-01-15 GB GB8001232A patent/GB2041925B/en not_active Expired
- 1980-01-18 CA CA000343988A patent/CA1144168A/en not_active Expired
- 1980-01-21 GR GR60998A patent/GR73567B/el unknown
- 1980-01-21 AU AU54765/80A patent/AU521986B2/en not_active Ceased
- 1980-01-21 CH CH456/80A patent/CH651040A5/fr not_active IP Right Cessation
- 1980-01-21 JP JP561180A patent/JPS55100386A/ja active Granted
- 1980-01-21 CH CH5785/83A patent/CH648314A5/fr not_active IP Right Cessation
- 1980-01-22 AT AT0033380A patent/AT376674B/de not_active IP Right Cessation
- 1980-01-22 LU LU82105A patent/LU82105A1/fr unknown
- 1980-01-22 NL NL8000385A patent/NL8000385A/nl not_active Application Discontinuation
- 1980-01-22 FI FI800179A patent/FI800179A/fi not_active Application Discontinuation
- 1980-01-22 DK DK25580A patent/DK25580A/da not_active Application Discontinuation
- 1980-01-22 BE BE0/199065A patent/BE881283A/fr not_active IP Right Cessation
- 1980-01-22 IL IL59189A patent/IL59189A/xx unknown
- 1980-01-22 IT IT19373/80A patent/IT1149927B/it active
- 1980-01-22 IE IE121/80A patent/IE49500B1/en unknown
- 1980-01-22 KR KR1019800000225A patent/KR830001932A/ko unknown
- 1980-01-22 DD DD80218578A patent/DD149071A5/de unknown
- 1980-01-22 FR FR8001301A patent/FR2447379A1/fr active Granted
- 1980-01-23 PT PT70724A patent/PT70724A/pt unknown
- 1980-01-23 DE DE19803002367 patent/DE3002367A1/de not_active Ceased
- 1980-05-16 JP JP55065153A patent/JPS5855151B2/ja not_active Expired
- 1980-05-16 JP JP6515580A patent/JPS5636487A/ja active Pending
- 1980-05-16 JP JP6515480A patent/JPS5636475A/ja active Pending
- 1980-05-28 FR FR8011815A patent/FR2453174A1/fr active Granted
- 1980-05-28 FR FR8011816A patent/FR2453175A1/fr active Granted
- 1980-06-17 PH PH24153A patent/PH15072A/en unknown
- 1980-06-17 PH PH24155A patent/PH15086A/en unknown
- 1980-06-17 PH PH24154A patent/PH17773A/en unknown
-
1981
- 1981-01-22 DD DD22761181A patent/DD156369A5/de unknown
- 1981-01-26 SU SU813233005A patent/SU1080746A3/ru active
- 1981-01-26 SU SU813233012A patent/SU1333239A3/ru active
-
1983
- 1983-12-13 YU YU02421/83A patent/YU242183A/xx unknown
-
1984
- 1984-07-27 NO NO843041A patent/NO843041L/no unknown
- 1984-09-11 SE SE8404554A patent/SE8404554L/xx unknown
- 1984-09-11 SE SE8404555A patent/SE8404555D0/xx not_active Application Discontinuation
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