NO136092C - Analogifremgangsm}te for fremstilling av terapeutisk aktiv 4-(4-bifenyl)-1-butanol. - Google Patents

Analogifremgangsm}te for fremstilling av terapeutisk aktiv 4-(4-bifenyl)-1-butanol.

Info

Publication number
NO136092C
NO136092C NO3683/72A NO368372A NO136092C NO 136092 C NO136092 C NO 136092C NO 3683/72 A NO3683/72 A NO 3683/72A NO 368372 A NO368372 A NO 368372A NO 136092 C NO136092 C NO 136092C
Authority
NO
Norway
Prior art keywords
biphenyl
butanol
preparation
therapeutic active
analogical procedure
Prior art date
Application number
NO3683/72A
Other languages
English (en)
Norwegian (no)
Other versions
NO136092B (ru
Inventor
Ernst Seeger
Wolfhard Engel
Helmut Teufel
Guenther Engelhardt
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO136092B publication Critical patent/NO136092B/no
Publication of NO136092C publication Critical patent/NO136092C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/10Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
    • C07C29/103Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes of cyclic ethers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C07C29/149Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/60Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by elimination of -OH groups, e.g. by dehydration
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • C07C33/24Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part polycyclic without condensed ring systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/26Polyhydroxylic alcohols containing only six-membered aromatic rings as cyclic part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
NO3683/72A 1971-10-15 1972-10-13 Analogifremgangsm}te for fremstilling av terapeutisk aktiv 4-(4-bifenyl)-1-butanol. NO136092C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2151312A DE2151312C3 (de) 1971-10-15 1971-10-15 4- (4-Biphen ylyl) -l-butanol

Publications (2)

Publication Number Publication Date
NO136092B NO136092B (ru) 1977-04-12
NO136092C true NO136092C (no) 1977-07-20

Family

ID=5822378

Family Applications (1)

Application Number Title Priority Date Filing Date
NO3683/72A NO136092C (no) 1971-10-15 1972-10-13 Analogifremgangsm}te for fremstilling av terapeutisk aktiv 4-(4-bifenyl)-1-butanol.

Country Status (28)

Country Link
US (1) US3801654A (ru)
JP (3) JPS5320031B2 (ru)
AT (7) AT321897B (ru)
AU (1) AU469279B2 (ru)
BE (1) BE790086A (ru)
BG (5) BG20777A3 (ru)
CA (1) CA993897A (ru)
CH (4) CH590185A5 (ru)
CS (7) CS160613B2 (ru)
DD (1) DD103233A5 (ru)
DE (1) DE2151312C3 (ru)
DK (1) DK129573B (ru)
ES (5) ES407583A1 (ru)
FI (1) FI55984C (ru)
FR (1) FR2157860B1 (ru)
GB (1) GB1361574A (ru)
HU (1) HU164696B (ru)
IE (1) IE36775B1 (ru)
IL (1) IL40571A (ru)
NL (1) NL7213927A (ru)
NO (1) NO136092C (ru)
PH (1) PH13645A (ru)
PL (4) PL91408B1 (ru)
RO (8) RO70567A (ru)
SE (2) SE399417B (ru)
SU (7) SU471710A3 (ru)
YU (5) YU255972A (ru)
ZA (1) ZA727320B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053639A (en) * 1964-01-24 1977-10-11 The Boots Company Limited Therapeutically active phenylalkane derivatives
BE790085A (fr) * 1971-10-15 1973-04-13 Thomae Gmbh Dr K Nouveaux 4-(4-biphenylyl)-butanols
DE2240440A1 (de) * 1972-08-17 1974-02-28 Thomae Gmbh Dr K Neue (4-biphenylyl)-alkohole und verfahren zu ihrer herstellung
DE2240438A1 (de) * 1972-08-17 1974-02-28 Thomae Gmbh Dr K Neue 2-(4-biphenylyl)-tetrahydrofurane und verfahren zu ihrer herstellung
DE2341506A1 (de) * 1973-08-16 1975-02-27 Thomae Gmbh Dr K Neue biphenylderivate und verfahren zu ihrer herstellung
DE2528958A1 (de) * 1975-06-28 1977-01-13 Merck Patent Gmbh Araliphatische dihalogenverbindungen und verfahren zu ihrer herstellung
DE2708520A1 (de) * 1977-02-26 1978-08-31 Thomae Gmbh Dr K Neue arzneimittelkombinationen und verfahren zu ihrer herstellung
DE3001303A1 (de) * 1980-01-16 1981-07-23 Basf Ag, 6700 Ludwigshafen Optisch aktive phenylpropan-derivate, ihre herstellung und verwendung
AT399471B (de) * 1993-06-04 1995-05-26 Ifw Manfred Otte Ges M B H & C Spritzgiessform

Also Published As

Publication number Publication date
IE36775L (en) 1973-04-15
CS160611B2 (ru) 1975-03-28
AU469279B2 (en) 1976-02-12
BG20560A3 (bg) 1975-12-05
ZA727320B (en) 1974-06-26
SU474968A3 (ru) 1975-06-25
AU4774872A (en) 1974-04-26
RO70059A (ro) 1980-03-15
RO71244A (ro) 1982-07-06
YU197279A (en) 1982-06-18
HU164696B (ru) 1974-03-28
YU197179A (en) 1982-06-18
JPS5387341A (en) 1978-08-01
IE36775B1 (en) 1977-02-16
FI55984B (fi) 1979-07-31
SU471710A3 (ru) 1975-05-25
CS160609B2 (ru) 1975-03-28
PL91407B1 (ru) 1977-02-28
US3801654A (en) 1974-04-02
DK129573C (ru) 1975-03-24
DK129573B (da) 1974-10-28
FR2157860B1 (ru) 1975-10-31
SE399417B (sv) 1978-02-13
JPS5515448B2 (ru) 1980-04-23
IL40571A0 (en) 1972-12-29
CH599082A5 (ru) 1978-05-12
SU464105A3 (ru) 1975-03-15
JPS5320031B2 (ru) 1978-06-24
CH575358A5 (ru) 1976-05-14
BG20777A3 (bg) 1975-12-20
SU496714A3 (ru) 1975-12-25
NO136092B (ru) 1977-04-12
DE2151312C3 (de) 1975-07-31
CS160610B2 (ru) 1975-03-28
IL40571A (en) 1975-10-15
DD103233A5 (ru) 1974-01-12
SU496713A3 (ru) 1975-12-25
CS160613B2 (ru) 1975-03-28
SU464106A3 (ru) 1975-03-15
GB1361574A (en) 1974-07-30
RO70567A (ro) 1981-07-30
ES415241A1 (es) 1976-06-16
JPS5387342A (en) 1978-08-01
RO71306A (ro) 1981-08-17
CS160615B2 (ru) 1975-03-28
AT321897B (de) 1975-04-25
RO70058A (ro) 1982-09-09
PL91408B1 (ru) 1977-02-28
YU255972A (en) 1982-06-18
AT321899B (de) 1975-04-25
NL7213927A (ru) 1973-04-17
RO69378A (ro) 1981-04-20
AT315823B (de) 1974-06-10
AT321901B (de) 1975-04-25
JPS4861459A (ru) 1973-08-28
JPS5542054B2 (ru) 1980-10-28
DE2151312A1 (de) 1973-04-19
BG20332A3 (bg) 1975-11-05
ES407583A1 (es) 1975-11-01
PL83601B1 (ru) 1975-12-31
SU453823A3 (ru) 1974-12-15
ES415243A1 (es) 1976-11-01
CA993897A (en) 1976-07-27
AT321900B (de) 1975-04-25
FI55984C (fi) 1979-11-12
YU197479A (en) 1982-06-18
YU197379A (en) 1982-06-18
PH13645A (en) 1980-08-18
PL91409B1 (ru) 1977-02-28
ES415244A1 (es) 1976-11-01
CH590185A5 (ru) 1977-07-29
CS160612B2 (ru) 1975-03-28
ATA573873A (de) 1975-04-15
SE7600800L (sv) 1976-01-26
RO71307A (ro) 1982-03-24
AT321898B (de) 1975-04-25
CS160614B2 (ru) 1975-03-28
RO70060A (ro) 1981-06-30
DE2151312B2 (ru) 1974-11-28
FR2157860A1 (ru) 1973-06-08
BE790086A (fr) 1973-04-13
BG20333A3 (bg) 1975-11-05
CH589575A5 (ru) 1977-07-15
BG19586A3 (bg) 1975-06-25
AT327177B (de) 1976-01-26
ES415242A1 (es) 1976-06-16

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