SU464105A3 - Способ получени 4-(4-бифенилил)-1 бутанола - Google Patents

Способ получени 4-(4-бифенилил)-1 бутанола

Info

Publication number
SU464105A3
SU464105A3 SU1955026A SU1955026A SU464105A3 SU 464105 A3 SU464105 A3 SU 464105A3 SU 1955026 A SU1955026 A SU 1955026A SU 1955026 A SU1955026 A SU 1955026A SU 464105 A3 SU464105 A3 SU 464105A3
Authority
SU
USSR - Soviet Union
Prior art keywords
biphenylyl
butanol
obtaining
hal
solvent
Prior art date
Application number
SU1955026A
Other languages
English (en)
Inventor
Зеегер Эрнст
Энгель Вольфгард
Тойфель Гельмут
Энгельхардт Гюнтер
Original Assignee
Д-Р Карл Томэ Гмбх (Фирма)
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Д-Р Карл Томэ Гмбх (Фирма) filed Critical Д-Р Карл Томэ Гмбх (Фирма)
Application granted granted Critical
Publication of SU464105A3 publication Critical patent/SU464105A3/ru

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/10—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
    • C07C29/103—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes of cyclic ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C07C29/149—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/60—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by elimination of -OH groups, e.g. by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • C07C33/24—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part polycyclic without condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/26—Polyhydroxylic alcohols containing only six-membered aromatic rings as cyclic part

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Rheumatology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)

Description

Предмет н з о б р е т е н и  

Claims (2)

  1. I. Способ получени  4-(4-бифе1-шлил)-1-буганола , отличающийс  тем, что соединение общей формулы
    CH2-CH2-Mq-Hal
    где Hal - атом хлора, брома или йода, подвергают взаимодействию с окисью этилена в присутствии растворител  с последующим выделением целевого продукта известными приемами.
  2. 2. Способ по п. 1, отличающийс  тем, что в качестве растворител  пр.имен ют диэтиловый эфир, тетрагидрофуран, диметоксиэтан , бензол или их смеси.
SU1955026A 1971-10-15 1972-10-12 Способ получени 4-(4-бифенилил)-1 бутанола SU464105A3 (ru)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2151312A DE2151312C3 (de) 1971-10-15 1971-10-15 4- (4-Biphen ylyl) -l-butanol

Publications (1)

Publication Number Publication Date
SU464105A3 true SU464105A3 (ru) 1975-03-15

Family

ID=5822378

Family Applications (7)

Application Number Title Priority Date Filing Date
SU1955030A SU464106A3 (ru) 1971-10-15 1972-10-12 Способ получени 4-(4-бифенилил)1 -бутанола
SU1957826A SU474968A3 (ru) 1971-10-15 1972-10-12 Способ получени 4-(4-бифенилил)1-бутанола
SU1955028A SU471710A3 (ru) 1971-10-15 1972-10-12 Способ получени 4-/4-бифенилил/1-бутанола
SU1839112A SU453823A3 (ru) 1971-10-15 1972-10-12 Способ получения 4-
SU1955026A SU464105A3 (ru) 1971-10-15 1972-10-12 Способ получени 4-(4-бифенилил)-1 бутанола
SU1955347A SU496713A3 (ru) 1971-10-15 1973-08-23 Способ получени 4-(2-бифенилил)1-бутанола
SU1955029A SU496714A3 (ru) 1971-10-15 1973-08-23 Способ получени 4-(4-бифенилил)1-бутанола

Family Applications Before (4)

Application Number Title Priority Date Filing Date
SU1955030A SU464106A3 (ru) 1971-10-15 1972-10-12 Способ получени 4-(4-бифенилил)1 -бутанола
SU1957826A SU474968A3 (ru) 1971-10-15 1972-10-12 Способ получени 4-(4-бифенилил)1-бутанола
SU1955028A SU471710A3 (ru) 1971-10-15 1972-10-12 Способ получени 4-/4-бифенилил/1-бутанола
SU1839112A SU453823A3 (ru) 1971-10-15 1972-10-12 Способ получения 4-

Family Applications After (2)

Application Number Title Priority Date Filing Date
SU1955347A SU496713A3 (ru) 1971-10-15 1973-08-23 Способ получени 4-(2-бифенилил)1-бутанола
SU1955029A SU496714A3 (ru) 1971-10-15 1973-08-23 Способ получени 4-(4-бифенилил)1-бутанола

Country Status (28)

Country Link
US (1) US3801654A (ru)
JP (3) JPS5320031B2 (ru)
AT (7) AT327177B (ru)
AU (1) AU469279B2 (ru)
BE (1) BE790086A (ru)
BG (5) BG20777A3 (ru)
CA (1) CA993897A (ru)
CH (4) CH589575A5 (ru)
CS (7) CS160609B2 (ru)
DD (1) DD103233A5 (ru)
DE (1) DE2151312C3 (ru)
DK (1) DK129573B (ru)
ES (5) ES407583A1 (ru)
FI (1) FI55984C (ru)
FR (1) FR2157860B1 (ru)
GB (1) GB1361574A (ru)
HU (1) HU164696B (ru)
IE (1) IE36775B1 (ru)
IL (1) IL40571A (ru)
NL (1) NL7213927A (ru)
NO (1) NO136092C (ru)
PH (1) PH13645A (ru)
PL (4) PL83601B1 (ru)
RO (8) RO70060A (ru)
SE (2) SE399417B (ru)
SU (7) SU464106A3 (ru)
YU (5) YU255972A (ru)
ZA (1) ZA727320B (ru)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053639A (en) * 1964-01-24 1977-10-11 The Boots Company Limited Therapeutically active phenylalkane derivatives
BE790085A (fr) * 1971-10-15 1973-04-13 Thomae Gmbh Dr K Nouveaux 4-(4-biphenylyl)-butanols
DE2240438A1 (de) * 1972-08-17 1974-02-28 Thomae Gmbh Dr K Neue 2-(4-biphenylyl)-tetrahydrofurane und verfahren zu ihrer herstellung
DE2240440A1 (de) * 1972-08-17 1974-02-28 Thomae Gmbh Dr K Neue (4-biphenylyl)-alkohole und verfahren zu ihrer herstellung
DE2341506A1 (de) * 1973-08-16 1975-02-27 Thomae Gmbh Dr K Neue biphenylderivate und verfahren zu ihrer herstellung
DE2528958A1 (de) * 1975-06-28 1977-01-13 Merck Patent Gmbh Araliphatische dihalogenverbindungen und verfahren zu ihrer herstellung
DE2708520A1 (de) * 1977-02-26 1978-08-31 Thomae Gmbh Dr K Neue arzneimittelkombinationen und verfahren zu ihrer herstellung
DE3001303A1 (de) * 1980-01-16 1981-07-23 Basf Ag, 6700 Ludwigshafen Optisch aktive phenylpropan-derivate, ihre herstellung und verwendung
AT399471B (de) * 1993-06-04 1995-05-26 Ifw Manfred Otte Ges M B H & C Spritzgiessform

Also Published As

Publication number Publication date
CS160615B2 (ru) 1975-03-28
ES415241A1 (es) 1976-06-16
AT315823B (de) 1974-06-10
FI55984B (fi) 1979-07-31
BG20332A3 (ru) 1975-11-05
NO136092C (no) 1977-07-20
AU469279B2 (en) 1976-02-12
BG20560A3 (ru) 1975-12-05
IL40571A (en) 1975-10-15
CH575358A5 (ru) 1976-05-14
SU496714A3 (ru) 1975-12-25
DD103233A5 (ru) 1974-01-12
CH599082A5 (ru) 1978-05-12
BE790086A (fr) 1973-04-13
SE7600800L (sv) 1976-01-26
BG19586A3 (ru) 1975-06-25
NL7213927A (ru) 1973-04-17
AT321901B (de) 1975-04-25
RO70058A (ro) 1982-09-09
PL91407B1 (ru) 1977-02-28
GB1361574A (en) 1974-07-30
RO71307A (ro) 1982-03-24
US3801654A (en) 1974-04-02
SU453823A3 (ru) 1974-12-15
AU4774872A (en) 1974-04-26
YU197179A (en) 1982-06-18
SU496713A3 (ru) 1975-12-25
JPS5387341A (en) 1978-08-01
PL83601B1 (ru) 1975-12-31
SU464106A3 (ru) 1975-03-15
AT321898B (de) 1975-04-25
ES415242A1 (es) 1976-06-16
DE2151312B2 (ru) 1974-11-28
FR2157860A1 (ru) 1973-06-08
AT327177B (de) 1976-01-26
JPS5515448B2 (ru) 1980-04-23
SE399417B (sv) 1978-02-13
AT321899B (de) 1975-04-25
IL40571A0 (en) 1972-12-29
RO71244A (ro) 1982-07-06
CA993897A (en) 1976-07-27
AT321900B (de) 1975-04-25
RO71306A (ro) 1981-08-17
ATA573873A (de) 1975-04-15
CH589575A5 (ru) 1977-07-15
BG20777A3 (ru) 1975-12-20
YU197479A (en) 1982-06-18
IE36775L (en) 1973-04-15
DK129573C (ru) 1975-03-24
SU471710A3 (ru) 1975-05-25
YU197379A (en) 1982-06-18
HU164696B (ru) 1974-03-28
CS160609B2 (ru) 1975-03-28
BG20333A3 (ru) 1975-11-05
DE2151312C3 (de) 1975-07-31
PH13645A (en) 1980-08-18
SU474968A3 (ru) 1975-06-25
RO70059A (ro) 1980-03-15
ES407583A1 (es) 1975-11-01
YU197279A (en) 1982-06-18
CS160614B2 (ru) 1975-03-28
PL91408B1 (ru) 1977-02-28
CS160610B2 (ru) 1975-03-28
CS160611B2 (ru) 1975-03-28
FR2157860B1 (ru) 1975-10-31
RO70567A (ro) 1981-07-30
CS160613B2 (ru) 1975-03-28
JPS5320031B2 (ru) 1978-06-24
DK129573B (da) 1974-10-28
JPS4861459A (ru) 1973-08-28
NO136092B (ru) 1977-04-12
ES415243A1 (es) 1976-11-01
PL91409B1 (ru) 1977-02-28
DE2151312A1 (de) 1973-04-19
YU255972A (en) 1982-06-18
RO69378A (ro) 1981-04-20
JPS5542054B2 (ru) 1980-10-28
ZA727320B (en) 1974-06-26
JPS5387342A (en) 1978-08-01
FI55984C (fi) 1979-11-12
CS160612B2 (ru) 1975-03-28
ES415244A1 (es) 1976-11-01
RO70060A (ro) 1981-06-30
AT321897B (de) 1975-04-25
CH590185A5 (ru) 1977-07-29
IE36775B1 (en) 1977-02-16

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