NO136492C - Analogifremgangsm}te for fremstilling av terapeutisk aktive 3-(trisubstituert benzoyl)-propionsyre. - Google Patents

Analogifremgangsm}te for fremstilling av terapeutisk aktive 3-(trisubstituert benzoyl)-propionsyre.

Info

Publication number
NO136492C
NO136492C NO3239/72A NO323972A NO136492C NO 136492 C NO136492 C NO 136492C NO 3239/72 A NO3239/72 A NO 3239/72A NO 323972 A NO323972 A NO 323972A NO 136492 C NO136492 C NO 136492C
Authority
NO
Norway
Prior art keywords
prophic
preparation
acid
therapeutic active
trisubstituted benzoyl
Prior art date
Application number
NO3239/72A
Other languages
English (en)
Other versions
NO136492B (no
Inventor
Tadakazu Murata
Hirosada Sugihara
Akira Nohara
Yasushi Sanno
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP7108871A external-priority patent/JPS5233108B2/ja
Priority claimed from JP7108771A external-priority patent/JPS5233107B2/ja
Priority claimed from JP316772A external-priority patent/JPS5233109B2/ja
Priority claimed from JP540172A external-priority patent/JPS5233623B2/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of NO136492B publication Critical patent/NO136492B/no
Publication of NO136492C publication Critical patent/NO136492C/no

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/84Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/90Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/50Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/60Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/44Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D317/46Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C07D317/48Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
    • C07D317/62Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
    • C07D317/64Oxygen atoms
NO3239/72A 1971-09-13 1972-09-12 Analogifremgangsm}te for fremstilling av terapeutisk aktive 3-(trisubstituert benzoyl)-propionsyre. NO136492C (no)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP7108871A JPS5233108B2 (no) 1971-09-13 1971-09-13
JP7108771A JPS5233107B2 (no) 1971-09-13 1971-09-13
JP316772A JPS5233109B2 (no) 1971-12-29 1971-12-29
JP540172A JPS5233623B2 (no) 1972-01-11 1972-01-11

Publications (2)

Publication Number Publication Date
NO136492B NO136492B (no) 1977-06-06
NO136492C true NO136492C (no) 1977-09-14

Family

ID=27453803

Family Applications (1)

Application Number Title Priority Date Filing Date
NO3239/72A NO136492C (no) 1971-09-13 1972-09-12 Analogifremgangsm}te for fremstilling av terapeutisk aktive 3-(trisubstituert benzoyl)-propionsyre.

Country Status (14)

Country Link
US (1) US3943169A (no)
AT (1) AT319216B (no)
AU (1) AU474825B2 (no)
BE (1) BE788749A (no)
CA (1) CA997360A (no)
CH (2) CH592038A5 (no)
DE (1) DE2244324C2 (no)
FR (1) FR2154503B1 (no)
GB (1) GB1387733A (no)
MY (1) MY7800304A (no)
NL (1) NL174547C (no)
NO (1) NO136492C (no)
PH (1) PH12087A (no)
SE (1) SE397974B (no)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1498903A (en) * 1974-03-25 1978-01-25 Fabre Sa Pierre Aromatic keto-acids and their derivatives
FR2481270A1 (fr) * 1980-04-24 1981-10-30 Roussel Uclaf Nouveaux derives substitues de l'acide 4-phenyl 4-oxo 2-hydroxy butanoique, procede pour leur preparation et applications comme medicaments
FR2481118A1 (fr) * 1980-04-24 1981-10-30 Roussel Uclaf Application a titre de medicaments de derives substitues de l'acide phenyl-4-oxo-2-butenoique
FR2489313A1 (fr) * 1980-09-04 1982-03-05 Hoechst France Procede de fabrication d'acides hydroxyarylglyoxyliques et de leurs sels alcalins et son application a la fabrication du para-hydroxyphenylglyoxylate de sodium
FR2504127B1 (fr) * 1981-04-17 1985-07-19 Roussel Uclaf Nouveaux derives d'acides phenyl aliphatique carboxyliques, procede pour leur preparation et leur application comme medicaments
FR2504004A1 (fr) 1981-04-17 1982-10-22 Roussel Uclaf Application a titre de medicaments de derives d'acides phenyl aliphatique carboxyliques
FR2515037A1 (fr) * 1981-10-22 1983-04-29 Roussel Uclaf A titre de medicaments, certains derives mono-substitues de l'acide 4-phenyl 4-oxo buten-2-oique, ainsi que les compositions les renfermant
IT1171605B (it) * 1981-10-22 1987-06-10 Roussel Maestretti Spa Derivati di acido 4-fenil-4-ossobuten-2-oico farmacologicamente attivi e procedimento per la loro preparazione
IT1210582B (it) * 1981-10-22 1989-09-14 Roussel Maestretti Spa Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta'farmacologiche e composizioni farmaceutiche che li contengono
NZ205559A (en) * 1982-09-23 1987-08-31 Merck Frosst Canada Inc Leukotriene antagonists, pharmaceutical compositions, and intermediates
US5135940A (en) * 1982-09-23 1992-08-04 Merck Frosst Canada, Inc. Leukotriene antagonists
SE454355B (sv) * 1983-01-24 1988-04-25 Roussel Uclaf Akrylsyraderivat innehallande en furyl-, pyranyl-, bensofuranyl-, oxazolyl- eller isoxazolylgrupp, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande nemnda derivat
IT1169783B (it) * 1983-08-25 1987-06-03 Roussel Maestretti Spa Derivati dell' acido 4-fenil 4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali
JPS6051168A (ja) * 1983-08-31 1985-03-22 Taisho Pharmaceut Co Ltd ジフェニルスルフィド誘導体
US4544565A (en) * 1984-03-29 1985-10-01 General Foods Corporation Foodstuffs containing sweetness inhibiting agents
CA1315279C (en) * 1987-01-12 1993-03-30 Nancy Grace Bollinger Anti-inflammatory agents
US5294613A (en) * 1987-01-12 1994-03-15 Eli Lilly And Company Method of treating endotoxic shock in mammals
US4945099A (en) * 1987-01-12 1990-07-31 Eli Lilly And Company Anti-inflammatory agents
US5098613A (en) * 1987-01-12 1992-03-24 Eli Lilly And Company Anti-inflammatory agents
CN108069847B (zh) * 2016-11-11 2022-06-17 湖南尔康制药股份有限公司 一种合成曲匹布通的方法
RU2733719C1 (ru) * 2019-04-23 2020-10-06 Общество С Ограниченной Ответственностью "Валента - Интеллект" Комбинация для лечения функциональных заболеваний органов желудочно-кишечного тракта

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2720542A (en) * 1954-08-24 1955-10-11 Merck & Co Inc 1-hydroxy-4-methoxy-7-keto-13-methyl-5, 6, 7, 9, 10, 13-hexahydrophenanthrene and processes of preparing the same
US3515731A (en) * 1966-06-17 1970-06-02 Pfizer & Co C Antibacterial agents
US3502679A (en) * 1967-05-31 1970-03-24 Sandoz Ag 10b-substituted 1,2,3,5,6,10b - hexahydropyrrolo(2,1-a)isoquinolines and process therefor
US3509132A (en) * 1967-07-14 1970-04-28 Sandoz Ag Decahydro-1,6-diazecines

Also Published As

Publication number Publication date
AT319216B (de) 1974-12-10
FR2154503B1 (no) 1976-03-05
AU4640572A (en) 1974-03-14
AU474825B2 (en) 1976-08-05
DE2244324A1 (de) 1973-04-12
CH592038A5 (no) 1977-10-14
PH12087A (en) 1978-10-30
NL7212375A (no) 1973-03-15
FR2154503A1 (no) 1973-05-11
BE788749A (fr) 1973-03-13
CH593900A5 (no) 1977-12-30
NL174547B (nl) 1984-02-01
DE2244324C2 (de) 1986-03-27
US3943169A (en) 1976-03-09
MY7800304A (en) 1978-12-31
CA997360A (en) 1976-09-21
NO136492B (no) 1977-06-06
SE397974B (sv) 1977-11-28
NL174547C (nl) 1984-07-02
GB1387733A (en) 1975-03-19

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