CA997360A - 3-(trisubstituted benzoyl)-propionic acid and a method for the production thereof - Google Patents
3-(trisubstituted benzoyl)-propionic acid and a method for the production thereofInfo
- Publication number
- CA997360A CA997360A CA151,485A CA151485A CA997360A CA 997360 A CA997360 A CA 997360A CA 151485 A CA151485 A CA 151485A CA 997360 A CA997360 A CA 997360A
- Authority
- CA
- Canada
- Prior art keywords
- production
- propionic acid
- trisubstituted benzoyl
- trisubstituted
- benzoyl
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C49/00—Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
- C07C49/76—Ketones containing a keto group bound to a six-membered aromatic ring
- C07C49/84—Ketones containing a keto group bound to a six-membered aromatic ring containing ether groups, groups, groups, or groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/76—Unsaturated compounds containing keto groups
- C07C59/90—Unsaturated compounds containing keto groups containing singly bound oxygen-containing groups
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/50—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to atoms of the carbocyclic ring
- C07D317/60—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D317/00—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
- C07D317/08—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
- C07D317/44—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D317/46—Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 ortho- or peri-condensed with carbocyclic rings or ring systems condensed with one six-membered ring
- C07D317/48—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring
- C07D317/62—Methylenedioxybenzenes or hydrogenated methylenedioxybenzenes, unsubstituted on the hetero ring with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to atoms of the carbocyclic ring
- C07D317/64—Oxygen atoms
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Medicinal Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7108771A JPS5233107B2 (no) | 1971-09-13 | 1971-09-13 | |
| JP7108871A JPS5233108B2 (no) | 1971-09-13 | 1971-09-13 | |
| JP316772A JPS5233109B2 (no) | 1971-12-29 | 1971-12-29 | |
| JP540172A JPS5233623B2 (no) | 1972-01-11 | 1972-01-11 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CA997360A true CA997360A (en) | 1976-09-21 |
Family
ID=27453803
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CA151,485A Expired CA997360A (en) | 1971-09-13 | 1972-09-12 | 3-(trisubstituted benzoyl)-propionic acid and a method for the production thereof |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US3943169A (no) |
| AT (1) | AT319216B (no) |
| AU (1) | AU474825B2 (no) |
| BE (1) | BE788749A (no) |
| CA (1) | CA997360A (no) |
| CH (2) | CH592038A5 (no) |
| DE (1) | DE2244324C2 (no) |
| FR (1) | FR2154503B1 (no) |
| GB (1) | GB1387733A (no) |
| MY (1) | MY7800304A (no) |
| NL (1) | NL174547C (no) |
| NO (1) | NO136492C (no) |
| PH (1) | PH12087A (no) |
| SE (1) | SE397974B (no) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4008323A (en) * | 1974-03-25 | 1977-02-15 | Pierre Fabre S.A. | Method of reducing cholesterol using certain aromatic keto acids |
| FR2481118A1 (fr) * | 1980-04-24 | 1981-10-30 | Roussel Uclaf | Application a titre de medicaments de derives substitues de l'acide phenyl-4-oxo-2-butenoique |
| FR2481270A1 (fr) * | 1980-04-24 | 1981-10-30 | Roussel Uclaf | Nouveaux derives substitues de l'acide 4-phenyl 4-oxo 2-hydroxy butanoique, procede pour leur preparation et applications comme medicaments |
| FR2489313A1 (fr) * | 1980-09-04 | 1982-03-05 | Hoechst France | Procede de fabrication d'acides hydroxyarylglyoxyliques et de leurs sels alcalins et son application a la fabrication du para-hydroxyphenylglyoxylate de sodium |
| FR2504004A1 (fr) | 1981-04-17 | 1982-10-22 | Roussel Uclaf | Application a titre de medicaments de derives d'acides phenyl aliphatique carboxyliques |
| FR2504127B1 (fr) * | 1981-04-17 | 1985-07-19 | Roussel Uclaf | Nouveaux derives d'acides phenyl aliphatique carboxyliques, procede pour leur preparation et leur application comme medicaments |
| GB2108500B (en) * | 1981-10-22 | 1985-05-15 | Roussel Uclaf | Aminobenzene medicaments |
| IT1210582B (it) * | 1981-10-22 | 1989-09-14 | Roussel Maestretti Spa | Derivati di acido 4-fenil-4-ossobuten-2-oico dotati di proprieta'farmacologiche e composizioni farmaceutiche che li contengono |
| FR2515037A1 (fr) * | 1981-10-22 | 1983-04-29 | Roussel Uclaf | A titre de medicaments, certains derives mono-substitues de l'acide 4-phenyl 4-oxo buten-2-oique, ainsi que les compositions les renfermant |
| IL69691A (en) * | 1982-09-23 | 1988-01-31 | Merck Frosst Canada Inc | Leukotriene antagonists,their preparation and pharmaceutical compositions containing them |
| US5135940A (en) * | 1982-09-23 | 1992-08-04 | Merck Frosst Canada, Inc. | Leukotriene antagonists |
| SE454355B (sv) * | 1983-01-24 | 1988-04-25 | Roussel Uclaf | Akrylsyraderivat innehallande en furyl-, pyranyl-, bensofuranyl-, oxazolyl- eller isoxazolylgrupp, forfarande for framstellning derav samt farmaceutiska kompositioner innehallande nemnda derivat |
| IT1169783B (it) * | 1983-08-25 | 1987-06-03 | Roussel Maestretti Spa | Derivati dell' acido 4-fenil 4-osso-buten 2-oico, loro procedimento di preparazione e loro applicazione come prodotti medicinali |
| JPS6051168A (ja) * | 1983-08-31 | 1985-03-22 | Taisho Pharmaceut Co Ltd | ジフェニルスルフィド誘導体 |
| US4544565A (en) * | 1984-03-29 | 1985-10-01 | General Foods Corporation | Foodstuffs containing sweetness inhibiting agents |
| US5098613A (en) * | 1987-01-12 | 1992-03-24 | Eli Lilly And Company | Anti-inflammatory agents |
| US5294613A (en) * | 1987-01-12 | 1994-03-15 | Eli Lilly And Company | Method of treating endotoxic shock in mammals |
| US4945099A (en) * | 1987-01-12 | 1990-07-31 | Eli Lilly And Company | Anti-inflammatory agents |
| CA1315279C (en) * | 1987-01-12 | 1993-03-30 | Nancy Grace Bollinger | Anti-inflammatory agents |
| CN108069847B (zh) * | 2016-11-11 | 2022-06-17 | 湖南尔康制药股份有限公司 | 一种合成曲匹布通的方法 |
| RU2733719C1 (ru) * | 2019-04-23 | 2020-10-06 | Общество С Ограниченной Ответственностью "Валента - Интеллект" | Комбинация для лечения функциональных заболеваний органов желудочно-кишечного тракта |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2720542A (en) * | 1954-08-24 | 1955-10-11 | Merck & Co Inc | 1-hydroxy-4-methoxy-7-keto-13-methyl-5, 6, 7, 9, 10, 13-hexahydrophenanthrene and processes of preparing the same |
| US3515731A (en) * | 1966-06-17 | 1970-06-02 | Pfizer & Co C | Antibacterial agents |
| US3502679A (en) * | 1967-05-31 | 1970-03-24 | Sandoz Ag | 10b-substituted 1,2,3,5,6,10b - hexahydropyrrolo(2,1-a)isoquinolines and process therefor |
| US3509132A (en) * | 1967-07-14 | 1970-04-28 | Sandoz Ag | Decahydro-1,6-diazecines |
-
0
- BE BE788749D patent/BE788749A/xx not_active IP Right Cessation
-
1972
- 1972-09-07 AU AU46405/72A patent/AU474825B2/en not_active Expired
- 1972-09-09 DE DE2244324A patent/DE2244324C2/de not_active Expired
- 1972-09-12 SE SE7211766A patent/SE397974B/xx unknown
- 1972-09-12 PH PH13895A patent/PH12087A/en unknown
- 1972-09-12 FR FR7232315A patent/FR2154503B1/fr not_active Expired
- 1972-09-12 CA CA151,485A patent/CA997360A/en not_active Expired
- 1972-09-12 NL NLAANVRAGE7212375,A patent/NL174547C/xx not_active IP Right Cessation
- 1972-09-12 NO NO3239/72A patent/NO136492C/no unknown
- 1972-09-12 US US05/288,348 patent/US3943169A/en not_active Expired - Lifetime
- 1972-09-13 GB GB4243672A patent/GB1387733A/en not_active Expired
- 1972-09-13 CH CH1340472A patent/CH592038A5/xx not_active IP Right Cessation
- 1972-09-13 AT AT1091773A patent/AT319216B/de not_active IP Right Cessation
-
1976
- 1976-09-13 CH CH1030476A patent/CH593900A5/xx not_active IP Right Cessation
-
1978
- 1978-12-30 MY MY304/78A patent/MY7800304A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NL174547C (nl) | 1984-07-02 |
| AU4640572A (en) | 1974-03-14 |
| GB1387733A (en) | 1975-03-19 |
| AT319216B (de) | 1974-12-10 |
| NL174547B (nl) | 1984-02-01 |
| BE788749A (fr) | 1973-03-13 |
| NL7212375A (no) | 1973-03-15 |
| NO136492B (no) | 1977-06-06 |
| DE2244324C2 (de) | 1986-03-27 |
| FR2154503A1 (no) | 1973-05-11 |
| NO136492C (no) | 1977-09-14 |
| AU474825B2 (en) | 1976-08-05 |
| US3943169A (en) | 1976-03-09 |
| SE397974B (sv) | 1977-11-28 |
| FR2154503B1 (no) | 1976-03-05 |
| CH592038A5 (no) | 1977-10-14 |
| DE2244324A1 (de) | 1973-04-12 |
| PH12087A (en) | 1978-10-30 |
| MY7800304A (en) | 1978-12-31 |
| CH593900A5 (no) | 1977-12-30 |
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