NO136092C - Analogifremgangsm}te for fremstilling av terapeutisk aktiv 4-(4-bifenyl)-1-butanol. - Google Patents

Analogifremgangsm}te for fremstilling av terapeutisk aktiv 4-(4-bifenyl)-1-butanol.

Info

Publication number
NO136092C
NO136092C NO3683/72A NO368372A NO136092C NO 136092 C NO136092 C NO 136092C NO 3683/72 A NO3683/72 A NO 3683/72A NO 368372 A NO368372 A NO 368372A NO 136092 C NO136092 C NO 136092C
Authority
NO
Norway
Prior art keywords
biphenyl
butanol
preparation
therapeutic active
analogical procedure
Prior art date
Application number
NO3683/72A
Other languages
English (en)
Norwegian (no)
Other versions
NO136092B (cs
Inventor
Ernst Seeger
Wolfhard Engel
Helmut Teufel
Guenther Engelhardt
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of NO136092B publication Critical patent/NO136092B/no
Publication of NO136092C publication Critical patent/NO136092C/no

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/09—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis
    • C07C29/10—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes
    • C07C29/103—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrolysis of ethers, including cyclic ethers, e.g. oxiranes of cyclic ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/143—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/132—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group
    • C07C29/136—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH
    • C07C29/147—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof
    • C07C29/149—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by reduction of an oxygen containing functional group of >C=O containing groups, e.g. —COOH of carboxylic acids or derivatives thereof with hydrogen or hydrogen-containing gases
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/17—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by hydrogenation of carbon-to-carbon double or triple bonds
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/36—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring increasing the number of carbon atoms by reactions with formation of hydroxy groups, which may occur via intermediates being derivatives of hydroxy, e.g. O-metal
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C29/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring
    • C07C29/60—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom not belonging to a six-membered aromatic ring by elimination of -OH groups, e.g. by dehydration
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/18—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part
    • C07C33/24—Monohydroxylic alcohols containing only six-membered aromatic rings as cyclic part polycyclic without condensed ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00—Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/26—Polyhydroxylic alcohols containing only six-membered aromatic rings as cyclic part
NO3683/72A 1971-10-15 1972-10-13 Analogifremgangsm}te for fremstilling av terapeutisk aktiv 4-(4-bifenyl)-1-butanol. NO136092C (no)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE2151312A DE2151312C3 (de) 1971-10-15 1971-10-15 4- (4-Biphen ylyl) -l-butanol

Publications (2)

Publication Number Publication Date
NO136092B NO136092B (cs) 1977-04-12
NO136092C true NO136092C (no) 1977-07-20

Family

ID=5822378

Family Applications (1)

Application Number Title Priority Date Filing Date
NO3683/72A NO136092C (no) 1971-10-15 1972-10-13 Analogifremgangsm}te for fremstilling av terapeutisk aktiv 4-(4-bifenyl)-1-butanol.

Country Status (28)

Country Link
US (1) US3801654A (cs)
JP (3) JPS5320031B2 (cs)
AT (7) AT321899B (cs)
AU (1) AU469279B2 (cs)
BE (1) BE790086A (cs)
BG (5) BG20560A3 (cs)
CA (1) CA993897A (cs)
CH (4) CH589575A5 (cs)
CS (7) CS160614B2 (cs)
DD (1) DD103233A5 (cs)
DE (1) DE2151312C3 (cs)
DK (1) DK129573B (cs)
ES (5) ES407583A1 (cs)
FI (1) FI55984C (cs)
FR (1) FR2157860B1 (cs)
GB (1) GB1361574A (cs)
HU (1) HU164696B (cs)
IE (1) IE36775B1 (cs)
IL (1) IL40571A (cs)
NL (1) NL7213927A (cs)
NO (1) NO136092C (cs)
PH (1) PH13645A (cs)
PL (4) PL91409B1 (cs)
RO (8) RO70567A (cs)
SE (2) SE399417B (cs)
SU (7) SU464105A3 (cs)
YU (5) YU255972A (cs)
ZA (1) ZA727320B (cs)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4053639A (en) * 1964-01-24 1977-10-11 The Boots Company Limited Therapeutically active phenylalkane derivatives
BE790085A (fr) * 1971-10-15 1973-04-13 Thomae Gmbh Dr K Nouveaux 4-(4-biphenylyl)-butanols
DE2240440A1 (de) * 1972-08-17 1974-02-28 Thomae Gmbh Dr K Neue (4-biphenylyl)-alkohole und verfahren zu ihrer herstellung
DE2240438A1 (de) * 1972-08-17 1974-02-28 Thomae Gmbh Dr K Neue 2-(4-biphenylyl)-tetrahydrofurane und verfahren zu ihrer herstellung
DE2341506A1 (de) * 1973-08-16 1975-02-27 Thomae Gmbh Dr K Neue biphenylderivate und verfahren zu ihrer herstellung
DE2528958A1 (de) * 1975-06-28 1977-01-13 Merck Patent Gmbh Araliphatische dihalogenverbindungen und verfahren zu ihrer herstellung
DE2708520A1 (de) * 1977-02-26 1978-08-31 Thomae Gmbh Dr K Neue arzneimittelkombinationen und verfahren zu ihrer herstellung
DE3001303A1 (de) * 1980-01-16 1981-07-23 Basf Ag, 6700 Ludwigshafen Optisch aktive phenylpropan-derivate, ihre herstellung und verwendung
AT399471B (de) * 1993-06-04 1995-05-26 Ifw Manfred Otte Ges M B H & C Spritzgiessform

Also Published As

Publication number Publication date
AU469279B2 (en) 1976-02-12
BG20560A3 (cs) 1975-12-05
CH599082A5 (cs) 1978-05-12
YU197279A (en) 1982-06-18
SU464106A3 (ru) 1975-03-15
CH589575A5 (cs) 1977-07-15
JPS5387341A (en) 1978-08-01
AT321900B (de) 1975-04-25
PH13645A (en) 1980-08-18
YU197479A (en) 1982-06-18
YU255972A (en) 1982-06-18
PL91409B1 (cs) 1977-02-28
DK129573B (da) 1974-10-28
AU4774872A (en) 1974-04-26
CS160612B2 (cs) 1975-03-28
DD103233A5 (cs) 1974-01-12
BG20332A3 (cs) 1975-11-05
NO136092B (cs) 1977-04-12
AT321898B (de) 1975-04-25
BE790086A (fr) 1973-04-13
IE36775B1 (en) 1977-02-16
SU474968A3 (ru) 1975-06-25
AT315823B (de) 1974-06-10
FI55984C (fi) 1979-11-12
RO70058A (ro) 1982-09-09
IL40571A (en) 1975-10-15
ES415243A1 (es) 1976-11-01
PL91407B1 (cs) 1977-02-28
ES415241A1 (es) 1976-06-16
BG19586A3 (cs) 1975-06-25
RO71307A (ro) 1982-03-24
IE36775L (en) 1973-04-15
SU471710A3 (ru) 1975-05-25
YU197379A (en) 1982-06-18
SE7600800L (sv) 1976-01-26
BG20777A3 (cs) 1975-12-20
PL91408B1 (cs) 1977-02-28
DE2151312A1 (de) 1973-04-19
GB1361574A (en) 1974-07-30
CS160610B2 (cs) 1975-03-28
RO69378A (ro) 1981-04-20
ES407583A1 (es) 1975-11-01
DE2151312C3 (de) 1975-07-31
JPS5387342A (en) 1978-08-01
CS160611B2 (cs) 1975-03-28
JPS5515448B2 (cs) 1980-04-23
AT321899B (de) 1975-04-25
FI55984B (fi) 1979-07-31
AT321897B (de) 1975-04-25
AT321901B (de) 1975-04-25
SU464105A3 (ru) 1975-03-15
IL40571A0 (en) 1972-12-29
RO70060A (ro) 1981-06-30
ES415242A1 (es) 1976-06-16
SE399417B (sv) 1978-02-13
NL7213927A (cs) 1973-04-17
RO70567A (ro) 1981-07-30
SU496713A3 (ru) 1975-12-25
RO70059A (ro) 1980-03-15
CS160613B2 (cs) 1975-03-28
AT327177B (de) 1976-01-26
JPS5320031B2 (cs) 1978-06-24
ZA727320B (en) 1974-06-26
CA993897A (en) 1976-07-27
CH575358A5 (cs) 1976-05-14
DE2151312B2 (cs) 1974-11-28
FR2157860A1 (cs) 1973-06-08
BG20333A3 (cs) 1975-11-05
ATA573873A (de) 1975-04-15
SU496714A3 (ru) 1975-12-25
US3801654A (en) 1974-04-02
SU453823A3 (ru) 1974-12-15
JPS4861459A (cs) 1973-08-28
RO71306A (ro) 1981-08-17
ES415244A1 (es) 1976-11-01
CS160609B2 (cs) 1975-03-28
HU164696B (cs) 1974-03-28
FR2157860B1 (cs) 1975-10-31
YU197179A (en) 1982-06-18
PL83601B1 (cs) 1975-12-31
RO71244A (ro) 1982-07-06
CS160615B2 (cs) 1975-03-28
JPS5542054B2 (cs) 1980-10-28
DK129573C (cs) 1975-03-24
CS160614B2 (cs) 1975-03-28
CH590185A5 (cs) 1977-07-29

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