NO135315B - - Google Patents

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Publication number
NO135315B
NO135315B NO7121A NO2171A NO135315B NO 135315 B NO135315 B NO 135315B NO 7121 A NO7121 A NO 7121A NO 2171 A NO2171 A NO 2171A NO 135315 B NO135315 B NO 135315B
Authority
NO
Norway
Prior art keywords
formula
tetrahydro
compound
rac
hydrochloride
Prior art date
Application number
NO7121A
Other languages
English (en)
Norwegian (no)
Other versions
NO135315C (de
Inventor
Jr A Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Priority to NO740555A priority Critical patent/NO740555L/no
Priority to NO740554A priority patent/NO135062C/no
Publication of NO135315B publication Critical patent/NO135315B/no
Publication of NO135315C publication Critical patent/NO135315C/no

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
NO7121A 1970-01-06 1971-01-05 NO135315C (de)

Priority Applications (2)

Application Number Priority Date Filing Date Title
NO740555A NO740555L (no) 1970-01-06 1974-02-19 Isokinolinderivater til anvendelse som mellomprodukter for fremstilling av 2-alkyl- eller 2-fenyl-lavere alkyl-1,2,3,4-tetrahydro-4-isokinolinderivater.
NO740554A NO135062C (de) 1970-01-06 1974-02-19

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (2)

Publication Number Publication Date
NO135315B true NO135315B (de) 1976-12-13
NO135315C NO135315C (de) 1977-03-23

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
NO7121A NO135315C (de) 1970-01-06 1971-01-05

Country Status (19)

Country Link
JP (1) JPS5515476B1 (de)
AT (1) AT303041B (de)
BE (1) BE761219A (de)
CA (1) CA999866A (de)
CH (2) CH538477A (de)
DE (1) DE2062001C2 (de)
DK (1) DK125021B (de)
ES (1) ES387016A1 (de)
FI (1) FI49503C (de)
FR (1) FR2081412B1 (de)
GB (1) GB1335261A (de)
IE (1) IE34859B1 (de)
IL (1) IL35916A (de)
NL (1) NL171444C (de)
NO (1) NO135315C (de)
PH (1) PH9682A (de)
SE (3) SE386672B (de)
YU (1) YU33660B (de)
ZA (1) ZA708590B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
DE60038185T2 (de) 1999-11-03 2009-02-19 Amr Technology, Inc. Arly- und heteroaryl-substituierte tetrahydroisoquinoline und ihre verwendung als hemmer der wiederaufnahme von norepinephrin, dopamin und serotonin
CN100436420C (zh) * 1999-11-03 2008-11-26 Amr科技公司 4-苯基取代的四氢异喹啉及其用于制备药物的用途
EP1113007A1 (de) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisochinolin-Verbindungen zur Verwendung als Östrogen-Agonisten/-Antagonisten
KR100821410B1 (ko) 2000-07-11 2008-04-10 에이엠알 테크놀로지, 인크. 4-페닐 치환된 테트라하이드로이소퀴놀린 및 이의치료학적 용도
KR101412339B1 (ko) 2004-07-15 2014-06-25 알바니 몰레큘라 리써치, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를차단하기 위한 용도
JP2008543880A (ja) * 2005-06-17 2008-12-04 ジヤンセン・フアーマシユーチカ・ナームローゼ・フエンノートシヤツプ ナフチリジン化合物
NZ565111A (en) 2005-07-15 2011-10-28 Amr Technology Inc Aryl-and heteroaryl-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
ES2446971T3 (es) 2009-05-12 2014-03-11 Albany Molecular Research, Inc. Tetrahidroisoquinolinas sustituidas con arilo, heteroarilo, y heterociclo y su uso
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
CN102595902B (zh) 2009-05-12 2015-04-29 阿尔巴尼分子研究公司 7-([1,2,4]三唑并[1,5-a]吡啶-6-基)-4-(3,4-二氯苯基)-1,2,3,4-四氢异喹啉及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
SE386672B (sv) 1976-08-16
YU1971A (en) 1977-06-30
IL35916A0 (en) 1971-02-25
YU33660B (en) 1977-12-31
PH9682A (en) 1976-02-10
ZA708590B (en) 1971-09-29
NL171444B (nl) 1982-11-01
JPS5515476B1 (de) 1980-04-23
DK125021B (da) 1972-12-18
SE399879B (sv) 1978-03-06
CH538477A (de) 1973-06-30
BE761219A (fr) 1971-07-05
IL35916A (en) 1973-11-28
FI49503B (de) 1975-04-01
FR2081412A1 (de) 1971-12-03
NL7018956A (de) 1971-07-08
NO135315C (de) 1977-03-23
CH527194A (de) 1972-08-31
CA999866A (en) 1976-11-16
SE368401B (de) 1974-07-01
NL171444C (nl) 1983-04-05
GB1335261A (en) 1973-10-24
AT303041B (de) 1972-11-10
FI49503C (fi) 1975-07-10
DE2062001C2 (de) 1986-10-16
IE34859B1 (en) 1975-09-03
IE34859L (en) 1971-07-06
ES387016A1 (es) 1976-05-01
DE2062001A1 (de) 1971-07-15
FR2081412B1 (de) 1974-04-12

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