SE399879B - Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat - Google Patents

Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat

Info

Publication number
SE399879B
SE399879B SE7313622A SE7313622A SE399879B SE 399879 B SE399879 B SE 399879B SE 7313622 A SE7313622 A SE 7313622A SE 7313622 A SE7313622 A SE 7313622A SE 399879 B SE399879 B SE 399879B
Authority
SE
Sweden
Prior art keywords
isokinoline
tetrahydro
phenyl
derivatives
preparation
Prior art date
Application number
SE7313622A
Other languages
English (en)
Inventor
Jr A Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE399879B publication Critical patent/SE399879B/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7313622A 1970-01-06 1973-10-05 Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat SE399879B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
SE399879B true SE399879B (sv) 1978-03-06

Family

ID=4179328

Family Applications (3)

Application Number Title Priority Date Filing Date
SE17063/70A SE368401B (sv) 1970-01-06 1970-12-16
SE7313623A SE386672B (sv) 1970-01-06 1970-12-16 Mellanprodukter for framstellning av isokinolinderivat
SE7313622A SE399879B (sv) 1970-01-06 1973-10-05 Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat

Family Applications Before (2)

Application Number Title Priority Date Filing Date
SE17063/70A SE368401B (sv) 1970-01-06 1970-12-16
SE7313623A SE386672B (sv) 1970-01-06 1970-12-16 Mellanprodukter for framstellning av isokinolinderivat

Country Status (19)

Country Link
JP (1) JPS5515476B1 (sv)
AT (1) AT303041B (sv)
BE (1) BE761219A (sv)
CA (1) CA999866A (sv)
CH (2) CH527194A (sv)
DE (1) DE2062001C2 (sv)
DK (1) DK125021B (sv)
ES (1) ES387016A1 (sv)
FI (1) FI49503C (sv)
FR (1) FR2081412B1 (sv)
GB (1) GB1335261A (sv)
IE (1) IE34859B1 (sv)
IL (1) IL35916A (sv)
NL (1) NL171444C (sv)
NO (1) NO135315C (sv)
PH (1) PH9682A (sv)
SE (3) SE368401B (sv)
YU (1) YU33660B (sv)
ZA (1) ZA708590B (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
MXPA02004330A (es) * 1999-11-03 2004-07-30 Albany Molecular Res Inc Tetrahidroisoquinolinas aril-y heteroaril-sustituidas y uso de las mismas para bloquear la recaptacion de norepinefrina, dopamina y serotonina..
KR20080065707A (ko) * 1999-11-03 2008-07-14 에이엠알 테크놀로지, 인크. 4-페닐-치환 테트라히드로이소퀴놀린, 및 노르에피네프린과도파민과 세로토닌의 재흡수를 차단하기 위한 이의 용도
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
NZ523456A (en) * 2000-07-11 2004-11-26 Albany Molecular Res Inc Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
US7541357B2 (en) 2004-07-15 2009-06-02 Amr Technology, Inc. Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
ATE409188T1 (de) * 2005-06-17 2008-10-15 Janssen Pharmaceutica Nv Naphthyridinverbindungen
GEP20125566B (en) 2005-07-15 2012-07-10 Amr Technology Inc Aryl-and heteroaryl-substituded tetrahydro-benzazepines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
PE20120373A1 (es) 2009-05-12 2012-05-17 Albany Molecular Res Inc 7-([1,2,4]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina
CN102458123A (zh) 2009-05-12 2012-05-16 阿尔巴尼分子研究公司 芳基、杂芳基和杂环取代的四氢异喹啉及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
JPS5515476B1 (sv) 1980-04-23
FI49503C (sv) 1975-07-10
CA999866A (en) 1976-11-16
GB1335261A (en) 1973-10-24
BE761219A (fr) 1971-07-05
DK125021B (da) 1972-12-18
NL171444B (nl) 1982-11-01
CH538477A (de) 1973-06-30
FR2081412B1 (sv) 1974-04-12
FI49503B (sv) 1975-04-01
FR2081412A1 (sv) 1971-12-03
NL171444C (nl) 1983-04-05
IE34859L (en) 1971-07-06
DE2062001A1 (de) 1971-07-15
IE34859B1 (en) 1975-09-03
IL35916A (en) 1973-11-28
NL7018956A (sv) 1971-07-08
DE2062001C2 (de) 1986-10-16
CH527194A (de) 1972-08-31
AT303041B (de) 1972-11-10
ES387016A1 (es) 1976-05-01
IL35916A0 (en) 1971-02-25
NO135315C (sv) 1977-03-23
SE386672B (sv) 1976-08-16
YU1971A (en) 1977-06-30
NO135315B (sv) 1976-12-13
PH9682A (en) 1976-02-10
SE368401B (sv) 1974-07-01
YU33660B (en) 1977-12-31
ZA708590B (en) 1971-09-29

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