AT303041B - Verfahren zur Herstellung von neuen Isochinolin-Derivaten und ihren Salzen - Google Patents

Verfahren zur Herstellung von neuen Isochinolin-Derivaten und ihren Salzen

Info

Publication number
AT303041B
AT303041B AT4571A AT4571A AT303041B AT 303041 B AT303041 B AT 303041B AT 4571 A AT4571 A AT 4571A AT 4571 A AT4571 A AT 4571A AT 303041 B AT303041 B AT 303041B
Authority
AT
Austria
Prior art keywords
salts
production
isoquinoline derivatives
new isoquinoline
new
Prior art date
Application number
AT4571A
Other languages
English (en)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Application granted granted Critical
Publication of AT303041B publication Critical patent/AT303041B/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00Carboxylic acid nitriles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT4571A 1970-01-06 1971-01-05 Verfahren zur Herstellung von neuen Isochinolin-Derivaten und ihren Salzen AT303041B (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
AT303041B true AT303041B (de) 1972-11-10

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
AT4571A AT303041B (de) 1970-01-06 1971-01-05 Verfahren zur Herstellung von neuen Isochinolin-Derivaten und ihren Salzen

Country Status (19)

Country Link
JP (1) JPS5515476B1 (de)
AT (1) AT303041B (de)
BE (1) BE761219A (de)
CA (1) CA999866A (de)
CH (2) CH538477A (de)
DE (1) DE2062001C2 (de)
DK (1) DK125021B (de)
ES (1) ES387016A1 (de)
FI (1) FI49503C (de)
FR (1) FR2081412B1 (de)
GB (1) GB1335261A (de)
IE (1) IE34859B1 (de)
IL (1) IL35916A (de)
NL (1) NL171444C (de)
NO (1) NO135315C (de)
PH (1) PH9682A (de)
SE (3) SE386672B (de)
YU (1) YU33660B (de)
ZA (1) ZA708590B (de)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
WO2001032625A1 (en) 1999-11-03 2001-05-10 Du Pont Pharmaceuticals Company Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
NZ519146A (en) * 1999-11-03 2004-02-27 Albany Molecular Res Inc 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
EP1113007A1 (de) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisochinolin-Verbindungen zur Verwendung als Östrogen-Agonisten/-Antagonisten
JP5132864B2 (ja) 2000-07-11 2013-01-30 アルバニー モレキュラー リサーチ, インコーポレイテッド 4−フェニル置換テトラヒドロイソキノリンおよびその使用方法
AU2005274927B2 (en) 2004-07-15 2011-11-03 Albany Molecular Research, Inc. Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
DE602006002894D1 (de) 2005-06-17 2008-11-06 Janssen Pharmaceutica Nv Naphthyridinverbindungen
KR101594898B1 (ko) 2005-07-15 2016-02-18 알바니 몰레큘라 리써치, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US8802696B2 (en) 2009-05-12 2014-08-12 Albany Molecular Research, Inc. 7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoqu inoli and use thereof
CN102458123A (zh) 2009-05-12 2012-05-16 阿尔巴尼分子研究公司 芳基、杂芳基和杂环取代的四氢异喹啉及其用途
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
YU1971A (en) 1977-06-30
FI49503B (de) 1975-04-01
FR2081412A1 (de) 1971-12-03
FI49503C (fi) 1975-07-10
ES387016A1 (es) 1976-05-01
NL171444C (nl) 1983-04-05
GB1335261A (en) 1973-10-24
JPS5515476B1 (de) 1980-04-23
NL7018956A (de) 1971-07-08
CH538477A (de) 1973-06-30
IL35916A (en) 1973-11-28
BE761219A (fr) 1971-07-05
IE34859L (en) 1971-07-06
SE386672B (sv) 1976-08-16
NO135315C (de) 1977-03-23
DE2062001A1 (de) 1971-07-15
IE34859B1 (en) 1975-09-03
DK125021B (da) 1972-12-18
IL35916A0 (en) 1971-02-25
SE368401B (de) 1974-07-01
NO135315B (de) 1976-12-13
CA999866A (en) 1976-11-16
NL171444B (nl) 1982-11-01
YU33660B (en) 1977-12-31
PH9682A (en) 1976-02-10
SE399879B (sv) 1978-03-06
FR2081412B1 (de) 1974-04-12
CH527194A (de) 1972-08-31
DE2062001C2 (de) 1986-10-16
ZA708590B (en) 1971-09-29

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Legal Events

Date Code Title Description
ELJ Ceased due to non-payment of the annual fee