SE386672B - Mellanprodukter for framstellning av isokinolinderivat - Google Patents

Mellanprodukter for framstellning av isokinolinderivat

Info

Publication number
SE386672B
SE386672B SE7313623A SE1362373A SE386672B SE 386672 B SE386672 B SE 386672B SE 7313623 A SE7313623 A SE 7313623A SE 1362373 A SE1362373 A SE 1362373A SE 386672 B SE386672 B SE 386672B
Authority
SE
Sweden
Prior art keywords
isokinoline
derivatives
manufacture
intermediate products
products
Prior art date
Application number
SE7313623A
Other languages
English (en)
Swedish (sv)
Inventor
Jr A Rheiner
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of SE386672B publication Critical patent/SE386672B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
SE7313623A 1970-01-06 1970-12-16 Mellanprodukter for framstellning av isokinolinderivat SE386672B (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
SE386672B true SE386672B (sv) 1976-08-16

Family

ID=4179328

Family Applications (3)

Application Number Title Priority Date Filing Date
SE17063/70A SE368401B (xx) 1970-01-06 1970-12-16
SE7313623A SE386672B (sv) 1970-01-06 1970-12-16 Mellanprodukter for framstellning av isokinolinderivat
SE7313622A SE399879B (sv) 1970-01-06 1973-10-05 Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat

Family Applications Before (1)

Application Number Title Priority Date Filing Date
SE17063/70A SE368401B (xx) 1970-01-06 1970-12-16

Family Applications After (1)

Application Number Title Priority Date Filing Date
SE7313622A SE399879B (sv) 1970-01-06 1973-10-05 Kemiska mellanprodukter till anvendning for framstellning av terapeutiskt verdefulla 1,2,3,4-tetrahydro-4-fenyl-isokinolinderivat

Country Status (19)

Country Link
JP (1) JPS5515476B1 (xx)
AT (1) AT303041B (xx)
BE (1) BE761219A (xx)
CA (1) CA999866A (xx)
CH (2) CH527194A (xx)
DE (1) DE2062001C2 (xx)
DK (1) DK125021B (xx)
ES (1) ES387016A1 (xx)
FI (1) FI49503C (xx)
FR (1) FR2081412B1 (xx)
GB (1) GB1335261A (xx)
IE (1) IE34859B1 (xx)
IL (1) IL35916A (xx)
NL (1) NL171444C (xx)
NO (1) NO135315C (xx)
PH (1) PH9682A (xx)
SE (3) SE368401B (xx)
YU (1) YU33660B (xx)
ZA (1) ZA708590B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
MXPA02004330A (es) * 1999-11-03 2004-07-30 Albany Molecular Res Inc Tetrahidroisoquinolinas aril-y heteroaril-sustituidas y uso de las mismas para bloquear la recaptacion de norepinefrina, dopamina y serotonina..
KR20080065707A (ko) * 1999-11-03 2008-07-14 에이엠알 테크놀로지, 인크. 4-페닐-치환 테트라히드로이소퀴놀린, 및 노르에피네프린과도파민과 세로토닌의 재흡수를 차단하기 위한 이의 용도
EP1113007A1 (en) * 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
NZ523456A (en) * 2000-07-11 2004-11-26 Albany Molecular Res Inc Novel 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
US7541357B2 (en) 2004-07-15 2009-06-02 Amr Technology, Inc. Aryl- and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
ATE409188T1 (de) * 2005-06-17 2008-10-15 Janssen Pharmaceutica Nv Naphthyridinverbindungen
GEP20125566B (en) 2005-07-15 2012-07-10 Amr Technology Inc Aryl-and heteroaryl-substituded tetrahydro-benzazepines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
WO2010132487A1 (en) 2009-05-12 2010-11-18 Bristol-Myers Squibb Company CRYSTALLINE FORMS OF (S)-7-([1,2,4]TRIAZOLO[1,5-a]PYRIDIN-6-YL)-4-(3,4-DICHLOROHPHENYL)-1,2,3,4-TETRAHYDROISOQUINOLINE AND USE THEREOF
PE20120373A1 (es) 2009-05-12 2012-05-17 Albany Molecular Res Inc 7-([1,2,4]triazolo[1,5-a]piridin-6-il)-4-(3,4-diclorofenil)-1,2,3,4-tetrahidroisoquinolina
CN102458123A (zh) 2009-05-12 2012-05-16 阿尔巴尼分子研究公司 芳基、杂芳基和杂环取代的四氢异喹啉及其用途

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
JPS5515476B1 (xx) 1980-04-23
FI49503C (fi) 1975-07-10
CA999866A (en) 1976-11-16
GB1335261A (en) 1973-10-24
BE761219A (fr) 1971-07-05
DK125021B (da) 1972-12-18
NL171444B (nl) 1982-11-01
CH538477A (de) 1973-06-30
SE399879B (sv) 1978-03-06
FR2081412B1 (xx) 1974-04-12
FI49503B (xx) 1975-04-01
FR2081412A1 (xx) 1971-12-03
NL171444C (nl) 1983-04-05
IE34859L (en) 1971-07-06
DE2062001A1 (de) 1971-07-15
IE34859B1 (en) 1975-09-03
IL35916A (en) 1973-11-28
NL7018956A (xx) 1971-07-08
DE2062001C2 (de) 1986-10-16
CH527194A (de) 1972-08-31
AT303041B (de) 1972-11-10
ES387016A1 (es) 1976-05-01
IL35916A0 (en) 1971-02-25
NO135315C (xx) 1977-03-23
YU1971A (en) 1977-06-30
NO135315B (xx) 1976-12-13
PH9682A (en) 1976-02-10
SE368401B (xx) 1974-07-01
YU33660B (en) 1977-12-31
ZA708590B (en) 1971-09-29

Similar Documents

Publication Publication Date Title
SE382459B (sv) Forfarande for framstellning av xantonderivat.
NO138280C (no) Fremgangsmaate for fremstilling av roerformede gjenstander
SE385885B (sv) Foerfarande foer framstaellning av 4-amino-6-arylpyrimidinderivat
SE394678B (sv) Analogiforfarande for framstellning av pyridokinolinderivat
SE386672B (sv) Mellanprodukter for framstellning av isokinolinderivat
SE420719B (sv) Forfarande for framstellning av karbamid
NO138883C (no) Fremgangsmaate for fremstilling av oksiranforbindelser
SE399701B (sv) Forfarande for framstellning av hydroxyalkyldiamin
SE382200B (sv) Forfarande for framstellning av veteperoxid
SE382457B (sv) Forfarande for framstellning av bensopyrankarbonsyror.
SE394436B (sv) Forfarande for framstellning av 7-halogen-linkomyciner
SE7511680L (sv) Forfarande for framstellning av furanderivat
FI54294B (fi) Foerfarande foer framstaellning av farmakologiskt verksamma isoindolinderivat
SE380273B (sv) Forfarande for framstellning av tiopyrimidinderivat
SE385011B (sv) Forfarande for framstellning av alfa-linkosaminider
SE384685B (sv) Forfarande for framstellning av linkomycinderivat
SE395699B (sv) Forfarande for framstellning av kinuklidin-kinolinderivat
SE408418B (sv) Forfarande for framstellning av 5-fluor-pyrimidiner
SE380796B (sv) Forfarande for framstellning av cyklopentanderivat
SE7602150L (sv) Mellanprodukter for framstellning av 4a-aryl-trans-dekahydroisokinolin
SE380795B (sv) Forfarande for framstellning av tiokarbamider
SE411759B (sv) Forfarande for framstellning av erytromycyliminforeningar
NO136409C (no) Fremgangsm}te for fremstilling av aryloksyalkyl-morfolinderivater
SE382046B (sv) Forfarande for framstellning av 1-aryloxi-2-propanol
SE380528B (sv) Forfarande for framstellning av 2-klor-7-hydroxi-11-piperazinyldibensoxazepmderivat