ES387016A1 - Un procedimiento para la preparacion de derivado de isoqui-nolina. - Google Patents

Un procedimiento para la preparacion de derivado de isoqui-nolina.

Info

Publication number
ES387016A1
ES387016A1 ES387016A ES387016A ES387016A1 ES 387016 A1 ES387016 A1 ES 387016A1 ES 387016 A ES387016 A ES 387016A ES 387016 A ES387016 A ES 387016A ES 387016 A1 ES387016 A1 ES 387016A1
Authority
ES
Spain
Prior art keywords
group
lower alkyl
hydroxy
general formula
isoquinoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES387016A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES387016A1 publication Critical patent/ES387016A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES387016A 1970-01-06 1971-01-05 Un procedimiento para la preparacion de derivado de isoqui-nolina. Expired ES387016A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
ES387016A1 true ES387016A1 (es) 1976-05-01

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
ES387016A Expired ES387016A1 (es) 1970-01-06 1971-01-05 Un procedimiento para la preparacion de derivado de isoqui-nolina.

Country Status (19)

Country Link
JP (1) JPS5515476B1 (xx)
AT (1) AT303041B (xx)
BE (1) BE761219A (xx)
CA (1) CA999866A (xx)
CH (2) CH527194A (xx)
DE (1) DE2062001C2 (xx)
DK (1) DK125021B (xx)
ES (1) ES387016A1 (xx)
FI (1) FI49503C (xx)
FR (1) FR2081412B1 (xx)
GB (1) GB1335261A (xx)
IE (1) IE34859B1 (xx)
IL (1) IL35916A (xx)
NL (1) NL171444C (xx)
NO (1) NO135315C (xx)
PH (1) PH9682A (xx)
SE (3) SE368401B (xx)
YU (1) YU33660B (xx)
ZA (1) ZA708590B (xx)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
BR0015320A (pt) 1999-11-03 2002-07-09 Albany Molecular Res Inc Composto, composição, métodos de tratamento de um distúrbio que e criado pela, ou é dependente da, disponibilidade diminuìda de serotonina, norepinefrina ou dopamina, para inibir a captação da serotonina, da dopamina e de norepinefrina sinápticas em um paciente em necessidade destes, e, kit
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
NZ519146A (en) * 1999-11-03 2004-02-27 Albany Molecular Res Inc 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
EP1113007A1 (en) 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
US7084152B2 (en) * 2000-07-11 2006-08-01 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines therapeutic use thereof
CA2573271C (en) 2004-07-15 2015-10-06 Amr Technology, Inc. Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
WO2006138714A2 (en) * 2005-06-17 2006-12-28 Janssen Pharmaceutica N.V. Naphthyridine compounds
JP5258561B2 (ja) 2005-07-15 2013-08-07 アルバニー モレキュラー リサーチ， インコーポレイテッド アリール置換およびヘテロアリール置換テトラヒドロベンズアゼピンならびにノルエピネフリン、ドーパミンおよびセロトニンの再取り込みを遮断するためのその使用
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
AU2010247763B2 (en) 2009-05-12 2015-12-24 Albany Molecular Research, Inc. 7-([1,2,4,]triazolo[1,5,-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4- tetrahydroisoquinoline and use thereof
KR20120023072A (ko) 2009-05-12 2012-03-12 브리스톨-마이어스 스큅 컴퍼니 （Ｓ）-7-（〔1,2,4〕트리아졸〔1,5-ａ〕피리딘-6-일）-4-（3,4-디클로로페닐）-1,2,3,4-테트라하이드로이소퀴놀린의 결정형 및 이의 용도
WO2010132437A1 (en) 2009-05-12 2010-11-18 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
NO135315B (xx) 1976-12-13
PH9682A (en) 1976-02-10
IL35916A0 (en) 1971-02-25
DE2062001A1 (de) 1971-07-15
GB1335261A (en) 1973-10-24
JPS5515476B1 (xx) 1980-04-23
SE368401B (xx) 1974-07-01
BE761219A (fr) 1971-07-05
FI49503B (xx) 1975-04-01
FR2081412A1 (xx) 1971-12-03
AT303041B (de) 1972-11-10
SE386672B (sv) 1976-08-16
NL171444B (nl) 1982-11-01
CA999866A (en) 1976-11-16
IE34859L (en) 1971-07-06
NL171444C (nl) 1983-04-05
DK125021B (da) 1972-12-18
IE34859B1 (en) 1975-09-03
FR2081412B1 (xx) 1974-04-12
NO135315C (xx) 1977-03-23
YU33660B (en) 1977-12-31
CH538477A (de) 1973-06-30
IL35916A (en) 1973-11-28
CH527194A (de) 1972-08-31
DE2062001C2 (de) 1986-10-16
NL7018956A (xx) 1971-07-08
SE399879B (sv) 1978-03-06
ZA708590B (en) 1971-09-29
YU1971A (en) 1977-06-30
FI49503C (fi) 1975-07-10

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19880205