FR2081412B1 - - Google Patents

Info

Publication number
FR2081412B1
FR2081412B1 FR7100097A FR7100097A FR2081412B1 FR 2081412 B1 FR2081412 B1 FR 2081412B1 FR 7100097 A FR7100097 A FR 7100097A FR 7100097 A FR7100097 A FR 7100097A FR 2081412 B1 FR2081412 B1 FR 2081412B1
Authority
FR
France
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
FR7100097A
Other versions
FR2081412A1 (fr
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2081412A1 publication Critical patent/FR2081412A1/fr
Application granted granted Critical
Publication of FR2081412B1 publication Critical patent/FR2081412B1/fr
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FR7100097A 1970-01-06 1971-01-05 Expired FR2081412B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (2)

Publication Number Publication Date
FR2081412A1 FR2081412A1 (fr) 1971-12-03
FR2081412B1 true FR2081412B1 (fr) 1974-04-12

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7100097A Expired FR2081412B1 (fr) 1970-01-06 1971-01-05

Country Status (19)

Country Link
JP (1) JPS5515476B1 (fr)
AT (1) AT303041B (fr)
BE (1) BE761219A (fr)
CA (1) CA999866A (fr)
CH (2) CH527194A (fr)
DE (1) DE2062001C2 (fr)
DK (1) DK125021B (fr)
ES (1) ES387016A1 (fr)
FI (1) FI49503C (fr)
FR (1) FR2081412B1 (fr)
GB (1) GB1335261A (fr)
IE (1) IE34859B1 (fr)
IL (1) IL35916A (fr)
NL (1) NL171444C (fr)
NO (1) NO135315C (fr)
PH (1) PH9682A (fr)
SE (3) SE368401B (fr)
YU (1) YU33660B (fr)
ZA (1) ZA708590B (fr)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
RU2309953C2 (ru) 1999-11-03 2007-11-10 Эймр Текнолоджи, Инк. Арил- и гетероарилзамещенные тетрагидроизохинолины, фармацевтическая композиция и способ лечения на их основе
CN100436420C (zh) * 1999-11-03 2008-11-26 Amr科技公司 4-苯基取代的四氢异喹啉及其用于制备药物的用途
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
EP1113007A1 (fr) 1999-12-24 2001-07-04 Pfizer Inc. Composés de tétrahydroisoquinoline comme agonistes/antagonistes d'oestrogène
CA2415532C (fr) 2000-07-11 2010-05-11 Albany Molecular Research, Inc. Nouvelles tetrahydroisoquinolines 4-phenyl substituees et leur utilisation a des fins therapeutiques
KR101412339B1 (ko) 2004-07-15 2014-06-25 알바니 몰레큘라 리써치, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로이소퀴놀린, 및이것의 노르에피네프린, 도파민 및 세로토닌의 재흡수를차단하기 위한 용도
EP1899334B1 (fr) 2005-06-17 2008-09-24 Janssen Pharmaceutica N.V. Composes de naphthyridine
CN101495184A (zh) 2005-07-15 2009-07-29 Amr科技公司 芳基和杂芳基取代的四氢苯并氮杂及其在阻断去甲肾上腺素多巴胺和血清素的重摄取中的应用
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
CA2760837C (fr) 2009-05-12 2018-04-03 Albany Molecular Research, Inc. 7-([1,2,4]triazolo[1,5-.alpha.]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline et son utilisation
US8815894B2 (en) 2009-05-12 2014-08-26 Bristol-Myers Squibb Company Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoquinoline and use thereof
US9034899B2 (en) 2009-05-12 2015-05-19 Albany Molecular Research, Inc. Aryl, heteroaryl, and heterocycle substituted tetrahydroisoquinolines and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
NL7018956A (fr) 1971-07-08
SE386672B (sv) 1976-08-16
PH9682A (en) 1976-02-10
DE2062001A1 (de) 1971-07-15
IL35916A0 (en) 1971-02-25
BE761219A (fr) 1971-07-05
NO135315B (fr) 1976-12-13
NL171444C (nl) 1983-04-05
SE368401B (fr) 1974-07-01
DE2062001C2 (de) 1986-10-16
ZA708590B (en) 1971-09-29
ES387016A1 (es) 1976-05-01
IL35916A (en) 1973-11-28
DK125021B (da) 1972-12-18
IE34859L (en) 1971-07-06
FI49503C (fi) 1975-07-10
IE34859B1 (en) 1975-09-03
FI49503B (fr) 1975-04-01
FR2081412A1 (fr) 1971-12-03
CA999866A (en) 1976-11-16
GB1335261A (en) 1973-10-24
CH538477A (de) 1973-06-30
SE399879B (sv) 1978-03-06
YU1971A (en) 1977-06-30
NO135315C (fr) 1977-03-23
NL171444B (nl) 1982-11-01
CH527194A (de) 1972-08-31
JPS5515476B1 (fr) 1980-04-23
AT303041B (de) 1972-11-10
YU33660B (en) 1977-12-31

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Legal Events

Date Code Title Description
ST Notification of lapse