ES387016A1 - Un procedimiento para la preparacion de derivado de isoqui-nolina. - Google Patents

Un procedimiento para la preparacion de derivado de isoqui-nolina.

Info

Publication number
ES387016A1
ES387016A1 ES387016A ES387016A ES387016A1 ES 387016 A1 ES387016 A1 ES 387016A1 ES 387016 A ES387016 A ES 387016A ES 387016 A ES387016 A ES 387016A ES 387016 A1 ES387016 A1 ES 387016A1
Authority
ES
Spain
Prior art keywords
group
lower alkyl
hydroxy
general formula
isoquinoline derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES387016A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES387016A1 publication Critical patent/ES387016A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C255/00—Carboxylic acid nitriles
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/14—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring other than aralkyl radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
ES387016A 1970-01-06 1971-01-05 Un procedimiento para la preparacion de derivado de isoqui-nolina. Expired ES387016A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH10370A CH527194A (de) 1970-01-06 1970-01-06 Verfahren zur Herstellung von Isochinolin-Derivaten

Publications (1)

Publication Number Publication Date
ES387016A1 true ES387016A1 (es) 1976-05-01

Family

ID=4179328

Family Applications (1)

Application Number Title Priority Date Filing Date
ES387016A Expired ES387016A1 (es) 1970-01-06 1971-01-05 Un procedimiento para la preparacion de derivado de isoqui-nolina.

Country Status (19)

Country Link
JP (1) JPS5515476B1 (sv)
AT (1) AT303041B (sv)
BE (1) BE761219A (sv)
CA (1) CA999866A (sv)
CH (2) CH538477A (sv)
DE (1) DE2062001C2 (sv)
DK (1) DK125021B (sv)
ES (1) ES387016A1 (sv)
FI (1) FI49503C (sv)
FR (1) FR2081412B1 (sv)
GB (1) GB1335261A (sv)
IE (1) IE34859B1 (sv)
IL (1) IL35916A (sv)
NL (1) NL171444C (sv)
NO (1) NO135315C (sv)
PH (1) PH9682A (sv)
SE (3) SE386672B (sv)
YU (1) YU33660B (sv)
ZA (1) ZA708590B (sv)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZA844402B (en) * 1983-06-23 1986-01-29 Mcneil Pharmaceutical Hexahydropyrrolo(2,1-a)isoquinoline derivatives
US4719216A (en) * 1983-06-23 1988-01-12 Mcneilab, Inc. Hexahydropyrrolo(2,1-A)isoquinoline derivatives as antidepressants
US4595688A (en) * 1983-06-23 1986-06-17 Mcneilab, Inc. Hexahydropyrrolo[2,1-a]isoquinoline derivatives and antidepressant use thereof
GB2271566A (en) * 1992-10-14 1994-04-20 Merck & Co Inc HIV integrase inhibitors
AU784280B2 (en) * 1999-11-03 2006-03-02 Albany Molecular Research, Inc. 4-phenyl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine and serotonin
US7163949B1 (en) * 1999-11-03 2007-01-16 Amr Technology, Inc. 4-phenyl substituted tetrahydroisoquinolines and use thereof
ES2304984T3 (es) 1999-11-03 2008-11-01 Amr Technology, Inc. Tetra-hidroisoquinolinas de sustitucion arilica y heteroarilica y su utilizacion para bloquear la recaptacion de norepinefrina, dopamina y serotonina.
EP1113007A1 (en) 1999-12-24 2001-07-04 Pfizer Inc. Tetrahydroisoquinoline compounds as estrogen agonists/antagonists
EP1299393A2 (en) 2000-07-11 2003-04-09 Bristol-Myers Squibb Pharma Company 4-phenyl substituted tetrahydroisoquinolines and therapeutic use thereof
NZ552397A (en) 2004-07-15 2011-04-29 Amr Technology Inc Aryl-and heteroaryl-substituted tetrahydroisoquinolines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
PL1899334T3 (pl) 2005-06-17 2009-04-30 Janssen Pharmaceutica Nv Związki naftyrydynowe
KR101589551B1 (ko) 2005-07-15 2016-02-02 알바니 몰레큘라 리써치, 인크. 아릴- 및 헤테로아릴-치환된 테트라히드로벤자제핀, 및 노르에피네프린, 도파민 및 세로토닌의 재흡수를 차단하기 위한 용도
AR071997A1 (es) 2008-06-04 2010-07-28 Bristol Myers Squibb Co Forma cristalina de 6-((4s)-2-metil-4-(2-naftil)-1,2,3,4-tetrahidroisoquinolin-7-il)piridazin-3-amina
US9156812B2 (en) 2008-06-04 2015-10-13 Bristol-Myers Squibb Company Crystalline form of 6-[(4S)-2-methyl-4-(2-naphthyl)-1,2,3,4-tetrahydroisoquinolin-7-yl]pyridazin-3-amine
KR20120034644A (ko) 2009-05-12 2012-04-12 알바니 몰레큘라 리써치, 인크. 아릴, 헤테로아릴, 및 헤테로사이클 치환된 테트라하이드로이소퀴놀린 및 이의 용도
AU2010247735B2 (en) 2009-05-12 2015-07-16 Albany Molecular Research, Inc. Crystalline forms of (S)-7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)- 1,2,3,4-tetrahydroisoquinoline and use thereof
US8802696B2 (en) 2009-05-12 2014-08-12 Albany Molecular Research, Inc. 7-([1,2,4]triazolo[1,5-a]pyridin-6-yl)-4-(3,4-dichlorophenyl)-1,2,3,4-tetrahydroisoqu inoli and use thereof

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1670694B2 (de) * 1966-05-05 1976-07-22 Hoechst Ag, 6000 Frankfurt Verfahren zur herstellung von tetrahydroisochinolinen

Also Published As

Publication number Publication date
SE399879B (sv) 1978-03-06
DK125021B (da) 1972-12-18
YU33660B (en) 1977-12-31
YU1971A (en) 1977-06-30
NO135315C (sv) 1977-03-23
DE2062001C2 (de) 1986-10-16
AT303041B (de) 1972-11-10
NO135315B (sv) 1976-12-13
IL35916A0 (en) 1971-02-25
PH9682A (en) 1976-02-10
IE34859L (en) 1971-07-06
CH527194A (de) 1972-08-31
BE761219A (fr) 1971-07-05
IL35916A (en) 1973-11-28
IE34859B1 (en) 1975-09-03
FI49503B (sv) 1975-04-01
FR2081412A1 (sv) 1971-12-03
SE386672B (sv) 1976-08-16
NL171444B (nl) 1982-11-01
NL7018956A (sv) 1971-07-08
JPS5515476B1 (sv) 1980-04-23
DE2062001A1 (de) 1971-07-15
NL171444C (nl) 1983-04-05
SE368401B (sv) 1974-07-01
FR2081412B1 (sv) 1974-04-12
CA999866A (en) 1976-11-16
CH538477A (de) 1973-06-30
FI49503C (sv) 1975-07-10
GB1335261A (en) 1973-10-24
ZA708590B (en) 1971-09-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19880205