NL9320021A - Farmaceutische samenstellingen die nifedipine bevatten en een werkwijze voor de bereiding daarvan. - Google Patents
Farmaceutische samenstellingen die nifedipine bevatten en een werkwijze voor de bereiding daarvan. Download PDFInfo
- Publication number
- NL9320021A NL9320021A NL9320021A NL9320021A NL9320021A NL 9320021 A NL9320021 A NL 9320021A NL 9320021 A NL9320021 A NL 9320021A NL 9320021 A NL9320021 A NL 9320021A NL 9320021 A NL9320021 A NL 9320021A
- Authority
- NL
- Netherlands
- Prior art keywords
- nifedipine
- polyvinylpyrrolidone
- composition
- acrylic
- copolymer
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
- A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
- A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Epidemiology (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
- Hydrogenated Pyridines (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB929200607A GB9200607D0 (en) | 1992-01-13 | 1992-01-13 | Pharmaceutical compositions containing nifedipine and process for the preparation thereof |
| GB9200607 | 1992-01-13 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL9320021A true NL9320021A (nl) | 1995-06-01 |
Family
ID=10708487
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL9320021A NL9320021A (nl) | 1992-01-13 | 1993-01-12 | Farmaceutische samenstellingen die nifedipine bevatten en een werkwijze voor de bereiding daarvan. |
Country Status (24)
| Country | Link |
|---|---|
| US (1) | US5594013A (is) |
| EP (1) | EP0620733B1 (is) |
| JP (1) | JPH07503003A (is) |
| AT (1) | ATE191144T1 (is) |
| AU (1) | AU659529B2 (is) |
| CA (1) | CA2126864A1 (is) |
| DE (2) | DE4390075T1 (is) |
| DK (2) | DK0620733T3 (is) |
| ES (1) | ES2146227T3 (is) |
| FI (1) | FI943316A (is) |
| GB (2) | GB9200607D0 (is) |
| HU (2) | HU219338B (is) |
| IS (1) | IS1620B (is) |
| MY (1) | MY110660A (is) |
| NL (1) | NL9320021A (is) |
| NO (1) | NO305223B1 (is) |
| NZ (1) | NZ246374A (is) |
| PH (1) | PH30985A (is) |
| PL (1) | PL170935B1 (is) |
| PT (1) | PT620733E (is) |
| RU (1) | RU2106139C1 (is) |
| SE (1) | SE9402457L (is) |
| WO (1) | WO1993013773A1 (is) |
| ZA (1) | ZA93195B (is) |
Families Citing this family (26)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| WO1994005262A1 (en) * | 1992-09-10 | 1994-03-17 | F.H. Faulding & Co. Limited | Sustained release matrix composition |
| US5455046A (en) * | 1993-09-09 | 1995-10-03 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems for insoluble drugs |
| US5773025A (en) * | 1993-09-09 | 1998-06-30 | Edward Mendell Co., Inc. | Sustained release heterodisperse hydrogel systems--amorphous drugs |
| US5871776A (en) * | 1995-01-31 | 1999-02-16 | Mehta; Atul M. | Controlled-release nifedipine |
| JPH11514979A (ja) * | 1995-09-07 | 1999-12-21 | フイズ テクノロジーズ リミテッド | 実質的に非溶解性の生体作用薬剤をバイオ・アベイラブルにするシステム |
| CO4771151A1 (es) * | 1996-01-19 | 1999-04-30 | Rachitzky Falicman Pablo Alberto | Procedimiento para la elaboracion de una preparacion farmace utica que contiene nifedipina y la preparacion farmaceutica obtenida mediante el mismo |
| CA2231195C (en) * | 1996-07-08 | 2003-01-21 | Edward Mendell Co., Inc. | Sustained release matrix for high-dose insoluble drugs |
| IT1284604B1 (it) * | 1996-09-27 | 1998-05-21 | Roberto Valducci | Composizioni farmaceutiche a rilascio controllato per somministrazione orale contenenti nifedipina come sostanza attiva |
| US5837379A (en) * | 1997-01-31 | 1998-11-17 | Andrx Pharmaceuticals, Inc. | Once daily pharmaceutical tablet having a unitary core |
| US5922352A (en) * | 1997-01-31 | 1999-07-13 | Andrx Pharmaceuticals, Inc. | Once daily calcium channel blocker tablet having a delayed release core |
| US6056977A (en) * | 1997-10-15 | 2000-05-02 | Edward Mendell Co., Inc. | Once-a-day controlled release sulfonylurea formulation |
| US6485748B1 (en) | 1997-12-12 | 2002-11-26 | Andrx Pharmaceuticals, Inc. | Once daily pharmaceutical tablet having a unitary core |
| US6264872B1 (en) | 1997-12-30 | 2001-07-24 | Kimberly-Clark Worldwide, Inc. | Method of forming thin, embossed, textured barrier films |
| US6969529B2 (en) | 2000-09-21 | 2005-11-29 | Elan Pharma International Ltd. | Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers |
| US6706283B1 (en) | 1999-02-10 | 2004-03-16 | Pfizer Inc | Controlled release by extrusion of solid amorphous dispersions of drugs |
| US6168806B1 (en) | 1999-03-05 | 2001-01-02 | Fang-Yu Lee | Orally administrable nifedipine pellet and process for the preparation thereof |
| ATE419834T1 (de) * | 2000-11-20 | 2009-01-15 | Elan Pharma Int Ltd | Nanopartikel bestehend aus einem arzneistoff und copolymeren von vinyl pyrrolidon und vinyl acetat als oberflächenstabilisatoren |
| SE0100200D0 (sv) * | 2001-01-24 | 2001-01-24 | Astrazeneca Ab | New film coating |
| SI1355633T1 (en) * | 2001-12-19 | 2005-06-30 | Astrazeneca Ab | NEW FILM COATING containing an ethyl acrylate/methyl methacrylate copolymer and polyvinyl acetate |
| US6620900B2 (en) * | 2002-02-07 | 2003-09-16 | Isp Investments Inc. | Proliferous copolymer of vinyl pyrrolidone and vinyl acetate |
| MY140561A (en) | 2002-02-20 | 2009-12-31 | Nycomed Gmbh | Dosage form containing pde 4 inhibitor as active ingredient |
| JP2005538809A (ja) * | 2002-09-18 | 2005-12-22 | メドトロニック ヴァスキュラー インコーポレイテッド | 医療装置のための制御可能な薬剤放出勾配コーティング |
| US9713592B2 (en) | 2005-04-06 | 2017-07-25 | Mallinckrodt Llc | Matrix-based pulse release pharmaceutical formulation |
| WO2007106111A2 (en) * | 2005-07-01 | 2007-09-20 | Elan Pharma International Limited | Nanoparticulate and controlled release compositions comprising nilvadipine |
| JP5351490B2 (ja) * | 2007-10-25 | 2013-11-27 | バイエル薬品株式会社 | ニフェジピン含有有核錠剤およびその製法 |
| RU2629843C1 (ru) * | 2016-05-24 | 2017-09-04 | федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) | Способ получения мази нифедипина (варианты) |
Family Cites Families (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2400819C2 (de) * | 1974-01-09 | 1982-04-22 | Bayer Ag, 5090 Leverkusen | Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung |
| GB1579818A (en) * | 1977-06-07 | 1980-11-26 | Yamanouchi Pharma Co Ltd | Nifedipine-containing solid preparation composition |
| EP0001247A1 (en) * | 1977-09-14 | 1979-04-04 | Kanebo, Ltd. | Pharmaceutical preparation containing nifedipine and a method for producing the same. |
| CA1146866A (en) * | 1979-07-05 | 1983-05-24 | Yamanouchi Pharmaceutical Co. Ltd. | Process for the production of sustained release pharmaceutical composition of solid medical material |
| ATE16500T1 (de) * | 1980-09-05 | 1985-11-15 | Argus Chem | Homogene, lagerbestaendige, fluessige bariumcadmium-triphosphit-stabilisierungssysteme fuer polyvinylchloridharze. |
| DE3033919A1 (de) * | 1980-09-09 | 1982-04-22 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung |
| JPS5846019A (ja) * | 1981-09-14 | 1983-03-17 | Kanebo Ltd | 持続性ニフエジピン製剤 |
| EP0078430B2 (de) * | 1981-10-29 | 1993-02-10 | Bayer Ag | Verfahren zur Herstellung von festen, schnellfreisetzenden Arzneizubereitungen mit Dihydropyridinen |
| DE3580384D1 (de) * | 1984-04-09 | 1990-12-13 | Toyo Boseki | Praeparat mit verzoegerter freigabe zum aufbringen auf die schleimhaeute der mundhoehle. |
| DE3424553A1 (de) * | 1984-07-04 | 1986-01-09 | Bayer Ag, 5090 Leverkusen | Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung |
| IT1178511B (it) * | 1984-09-14 | 1987-09-09 | Pharmatec Spa | Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio |
| DE3438830A1 (de) * | 1984-10-23 | 1986-04-30 | Rentschler Arzneimittel | Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung |
| FR2579510B1 (fr) * | 1985-03-29 | 1989-12-15 | Demler Sa Ets | Table vibrante pour la fabrication de produits en beton |
| FR2585174B1 (fr) * | 1985-07-16 | 1987-11-27 | Eurofarad | Procede de fabrication d'un composant capacitif multicouche a dielectrique ceramique du type cordierite, et composant ainsi obtenu |
| IE63321B1 (en) * | 1986-02-03 | 1995-04-05 | Elan Corp Plc | Drug delivery system |
| SE8601624D0 (sv) * | 1986-04-11 | 1986-04-11 | Haessle Ab | New pharmaceutical preparations |
| GB8613689D0 (en) * | 1986-06-05 | 1986-07-09 | Euro Celtique Sa | Pharmaceutical composition |
| US4970075A (en) * | 1986-07-18 | 1990-11-13 | Euroceltique, S.A. | Controlled release bases for pharmaceuticals |
| IE59540B1 (en) * | 1987-01-09 | 1994-03-09 | Elan Corp | Sustained release capsule or tablet formulation |
| US4968508A (en) * | 1987-02-27 | 1990-11-06 | Eli Lilly And Company | Sustained release matrix |
| GB8722306D0 (en) * | 1987-09-22 | 1987-10-28 | Aps Research Ltd | Sustained-release formulation |
| GB8903328D0 (en) * | 1989-02-14 | 1989-04-05 | Ethical Pharma Ltd | Nifedipine-containing pharmaceutical compositions and process for the preparation thereof |
| ES2077023T3 (es) * | 1989-03-10 | 1995-11-16 | Yamanouchi Pharma Co Ltd | Material de recubrimiento que controla la liberacion de un medicamento para formulaciones de actividad prolongada. |
| HU203041B (en) * | 1989-03-14 | 1991-05-28 | Egyt Gyogyszervegyeszeti Gyar | Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin |
| JPH0729926B2 (ja) * | 1989-07-25 | 1995-04-05 | 大塚製薬株式会社 | 易吸収性製剤用組成物 |
-
1992
- 1992-01-13 GB GB929200607A patent/GB9200607D0/en active Pending
-
1993
- 1993-01-11 IS IS3966A patent/IS1620B/is unknown
- 1993-01-12 PH PH45554A patent/PH30985A/en unknown
- 1993-01-12 EP EP93901850A patent/EP0620733B1/en not_active Expired - Lifetime
- 1993-01-12 AU AU32636/93A patent/AU659529B2/en not_active Ceased
- 1993-01-12 ZA ZA93195A patent/ZA93195B/xx unknown
- 1993-01-12 CA CA002126864A patent/CA2126864A1/en not_active Abandoned
- 1993-01-12 RU RU94035739A patent/RU2106139C1/ru active
- 1993-01-12 GB GB9413101A patent/GB2277872B/en not_active Expired - Fee Related
- 1993-01-12 HU HU9401850A patent/HU219338B/hu not_active IP Right Cessation
- 1993-01-12 PT PT93901850T patent/PT620733E/pt unknown
- 1993-01-12 NZ NZ246374A patent/NZ246374A/en unknown
- 1993-01-12 PL PL93300638A patent/PL170935B1/pl unknown
- 1993-01-12 ES ES93901850T patent/ES2146227T3/es not_active Expired - Lifetime
- 1993-01-12 US US08/256,398 patent/US5594013A/en not_active Expired - Lifetime
- 1993-01-12 JP JP5512264A patent/JPH07503003A/ja active Pending
- 1993-01-12 WO PCT/GB1993/000055 patent/WO1993013773A1/en active IP Right Grant
- 1993-01-12 NL NL9320021A patent/NL9320021A/nl not_active Application Discontinuation
- 1993-01-12 MY MYPI93000048A patent/MY110660A/en unknown
- 1993-01-12 DK DK93901850T patent/DK0620733T3/da active
- 1993-01-12 AT AT93901850T patent/ATE191144T1/de not_active IP Right Cessation
- 1993-01-12 DE DE4390075T patent/DE4390075T1/de not_active Withdrawn
- 1993-01-12 DE DE69328245T patent/DE69328245T2/de not_active Expired - Fee Related
-
1994
- 1994-07-11 DK DK083794A patent/DK83794A/da not_active Application Discontinuation
- 1994-07-12 NO NO942622A patent/NO305223B1/no unknown
- 1994-07-12 SE SE9402457A patent/SE9402457L/ not_active Application Discontinuation
- 1994-07-12 FI FI943316A patent/FI943316A/fi unknown
-
1995
- 1995-01-11 HU HU95P/P00065P patent/HU210539A9/hu unknown
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| BI | The patent application has been withdrawn | ||
| BA | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| BV | The patent application has lapsed |