IT1178511B - Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio - Google Patents

Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio

Info

Publication number
IT1178511B
IT1178511B IT22678/84A IT2267884A IT1178511B IT 1178511 B IT1178511 B IT 1178511B IT 22678/84 A IT22678/84 A IT 22678/84A IT 2267884 A IT2267884 A IT 2267884A IT 1178511 B IT1178511 B IT 1178511B
Authority
IT
Italy
Prior art keywords
nifedipine
preparation
oral use
use based
release
Prior art date
Application number
IT22678/84A
Other languages
English (en)
Other versions
IT8422678A0 (it
Inventor
Vittorio Giudice
Vittorino Ravelli
Original Assignee
Pharmatec Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=11199169&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=IT1178511(B) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Publication of IT8422678A0 publication Critical patent/IT8422678A0/it
Priority to IT22678/84A priority Critical patent/IT1178511B/it
Application filed by Pharmatec Spa filed Critical Pharmatec Spa
Priority to AU49594/85A priority patent/AU588258B2/en
Priority to PCT/EP1985/000481 priority patent/WO1986001717A1/en
Priority to DE8585904808T priority patent/DE3582251D1/de
Priority to AT85904808T priority patent/ATE61733T1/de
Priority to EP85904808A priority patent/EP0226588B1/en
Priority to JP60504334A priority patent/JPS62500660A/ja
Priority to ZA856862A priority patent/ZA856862B/xx
Priority to PT81113A priority patent/PT81113B/pt
Priority to CA000490628A priority patent/CA1253079A/en
Priority to YU143985A priority patent/YU45988B/sh
Priority to IE226285A priority patent/IE58490B1/en
Priority to ES547707A priority patent/ES8702137A1/es
Priority to NO86861845A priority patent/NO171887C/no
Priority to DK198602221A priority patent/DK172710B1/da
Priority to FI871116A priority patent/FI87991C/fi
Publication of IT1178511B publication Critical patent/IT1178511B/it
Application granted granted Critical

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
    • A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Hydrogenated Pyridines (AREA)
  • Cosmetics (AREA)
  • Electroplating And Plating Baths Therefor (AREA)
  • Surgical Instruments (AREA)
  • Silver Salt Photography Or Processing Solution Therefor (AREA)
  • Steering Control In Accordance With Driving Conditions (AREA)
IT22678/84A 1984-09-14 1984-09-14 Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio IT1178511B (it)

Priority Applications (16)

Application Number Priority Date Filing Date Title
IT22678/84A IT1178511B (it) 1984-09-14 1984-09-14 Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio
AU49594/85A AU588258B2 (en) 1984-09-14 1985-09-04 Controlled release nifedipine preparation
PCT/EP1985/000481 WO1986001717A1 (en) 1984-09-14 1985-09-04 Controlled release nifedipine preparation
DE8585904808T DE3582251D1 (de) 1984-09-14 1985-09-04 Verfahren zur herstellung einer festen form fuer orale verwendung auf der grundlage von nifedipin mit gesteuerter freigabe der aktiven substanz.
AT85904808T ATE61733T1 (de) 1984-09-14 1985-09-04 Verfahren zur herstellung einer festen form fuer orale verwendung auf der grundlage von nifedipin mit gesteuerter freigabe der aktiven substanz.
EP85904808A EP0226588B1 (en) 1984-09-14 1985-09-04 Process for preparation of a solid form for oral use based on nifedipine with controlled release of the active substance
JP60504334A JPS62500660A (ja) 1984-09-14 1985-09-04 活性物質の制御放出を伴うニフェディピンを基礎とする内服用固体の製造方法
ZA856862A ZA856862B (en) 1984-09-14 1985-09-06 Process for preparation of a solid form for oral use based on nifedipine with controlled release of the active substance
PT81113A PT81113B (pt) 1984-09-14 1985-09-12 Processo para a preparacao de um produto solido para administracao oral baseado em nifedifina, com libertacao controlada da substancia activa
CA000490628A CA1253079A (en) 1984-09-14 1985-09-12 Process for preparation of a solid form for oral use based on nifedipine with controlled release of the active substance
YU143985A YU45988B (sh) 1984-09-14 1985-09-13 Postupak za izradu čvrste kompozicije za oralnu upotrebu na bazi nifedipina sa kontrolisanim otpuštanjem aktivne supstance
IE226285A IE58490B1 (en) 1984-09-14 1985-09-13 Process for preparation of a solid form for oral use based on nifedipine with controlled release of the active substance
ES547707A ES8702137A1 (es) 1984-09-14 1985-09-13 Procedimiento de preparar una forma solidad de administracion farmaceutica para uso oral.
NO86861845A NO171887C (no) 1984-09-14 1986-05-07 Fremgangsmaate for fremstilling av en fast administreringsform for oral anvendelse basert paa nifedipin med kontrollert frigivelse av det aktive stoffet
DK198602221A DK172710B1 (da) 1984-09-14 1986-05-13 Fremgangsmåde til fremstilling af en fast form til oral anvendelse baseret på nifedipin med reguleret frigørelse af aktivst
FI871116A FI87991C (fi) 1984-09-14 1987-03-13 Foerfarande foer framstaellning av ett fast, pao nifedipin baserat preparat

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IT22678/84A IT1178511B (it) 1984-09-14 1984-09-14 Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio

Publications (2)

Publication Number Publication Date
IT8422678A0 IT8422678A0 (it) 1984-09-14
IT1178511B true IT1178511B (it) 1987-09-09

Family

ID=11199169

Family Applications (1)

Application Number Title Priority Date Filing Date
IT22678/84A IT1178511B (it) 1984-09-14 1984-09-14 Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio

Country Status (16)

Country Link
EP (1) EP0226588B1 (it)
JP (1) JPS62500660A (it)
AT (1) ATE61733T1 (it)
AU (1) AU588258B2 (it)
CA (1) CA1253079A (it)
DE (1) DE3582251D1 (it)
DK (1) DK172710B1 (it)
ES (1) ES8702137A1 (it)
FI (1) FI87991C (it)
IE (1) IE58490B1 (it)
IT (1) IT1178511B (it)
NO (1) NO171887C (it)
PT (1) PT81113B (it)
WO (1) WO1986001717A1 (it)
YU (1) YU45988B (it)
ZA (1) ZA856862B (it)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1187751B (it) * 1985-10-15 1987-12-23 Eurand Spa Procedimento per la preparazione di formulazioni solidi di nifedipina ad elevata biodisponibilita' e ad effetto prolungato e formulazioni cosi' ottenute
SE8601624D0 (sv) * 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
DK173505B1 (da) * 1987-02-20 2001-01-15 Pharmatec Internat S R L Fremgangsmåde til fremstilling af en diltiazempellet med langsom afgivelse og anvendelse af således fremstillede pelleter t
GB8722306D0 (en) * 1987-09-22 1987-10-28 Aps Research Ltd Sustained-release formulation
GB8903328D0 (en) * 1989-02-14 1989-04-05 Ethical Pharma Ltd Nifedipine-containing pharmaceutical compositions and process for the preparation thereof
HU203041B (en) * 1989-03-14 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin
US5122384A (en) * 1989-05-05 1992-06-16 Kv Pharmaceutical Company Oral once-per-day organic nitrate formulation which does not induce tolerance
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
GB9200607D0 (en) * 1992-01-13 1992-03-11 Ethical Pharma Ltd Pharmaceutical compositions containing nifedipine and process for the preparation thereof
WO1994005262A1 (en) * 1992-09-10 1994-03-17 F.H. Faulding & Co. Limited Sustained release matrix composition
US6077533A (en) * 1994-05-25 2000-06-20 Purdue Pharma L.P. Powder-layered oral dosage forms
US7060293B1 (en) 1994-05-25 2006-06-13 Purdue Pharma Powder-layered oral dosage forms
DE59410044D1 (de) * 1994-12-29 2002-03-21 Shire Deutschland Gmbh & Co Kg Pharmazeutische zubereitungen, enthaltend nifedipin und verfahren zu ihrer herstellung

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2453642A1 (fr) * 1979-04-12 1980-11-07 Sanofi Sa Compositions therapeutiques a usage oral et a liberation programmee du methanesulfonate de dihydroergotoxine
DE3033919A1 (de) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
DE3433239A1 (de) * 1984-09-11 1986-03-20 Bayer Ag, 5090 Leverkusen Feste arzneizubereitung enthaltend nitrendipin und verfahren zu ihrer herstellung
IE58110B1 (en) * 1984-10-30 1993-07-14 Elan Corp Plc Controlled release powder and process for its preparation

Also Published As

Publication number Publication date
DK222186D0 (da) 1986-05-13
IT8422678A0 (it) 1984-09-14
IE852262L (en) 1986-03-14
FI87991C (fi) 1993-03-25
WO1986001717A1 (en) 1986-03-27
FI871116A0 (fi) 1987-03-13
ZA856862B (en) 1986-05-28
IE58490B1 (en) 1993-09-22
DK222186A (da) 1986-05-13
NO861845L (no) 1986-05-07
NO171887C (no) 1993-05-19
JPS62500660A (ja) 1987-03-19
AU588258B2 (en) 1989-09-14
YU143985A (en) 1987-10-31
JPH0417932B2 (it) 1992-03-26
CA1253079A (en) 1989-04-25
DK172710B1 (da) 1999-06-07
DE3582251D1 (de) 1991-04-25
NO171887B (no) 1993-02-08
AU4959485A (en) 1986-04-08
EP0226588B1 (en) 1991-03-20
PT81113B (pt) 1987-10-20
ATE61733T1 (de) 1991-04-15
EP0226588A1 (en) 1987-07-01
ES547707A0 (es) 1987-01-16
FI871116A (fi) 1987-03-13
YU45988B (sh) 1992-12-21
FI87991B (fi) 1992-12-15
PT81113A (en) 1985-10-01
ES8702137A1 (es) 1987-01-16

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