DK0620733T3 - Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf - Google Patents

Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf

Info

Publication number
DK0620733T3
DK0620733T3 DK93901850T DK93901850T DK0620733T3 DK 0620733 T3 DK0620733 T3 DK 0620733T3 DK 93901850 T DK93901850 T DK 93901850T DK 93901850 T DK93901850 T DK 93901850T DK 0620733 T3 DK0620733 T3 DK 0620733T3
Authority
DK
Denmark
Prior art keywords
pct
nifedipine
pharmaceutical compositions
preparation
compositions containing
Prior art date
Application number
DK93901850T
Other languages
English (en)
Inventor
David Trigger
Original Assignee
Ethical Pharmaceuticals U K Li
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ethical Pharmaceuticals U K Li filed Critical Ethical Pharmaceuticals U K Li
Application granted granted Critical
Publication of DK0620733T3 publication Critical patent/DK0620733T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
    • A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/146—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic macromolecular compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/167—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface
    • A61K9/1676—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction with an outer layer or coating comprising drug; with chemically bound drugs or non-active substances on their surface having a drug-free core with discrete complete coating layer containing drug
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
DK93901850T 1992-01-13 1993-01-12 Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf DK0620733T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB929200607A GB9200607D0 (en) 1992-01-13 1992-01-13 Pharmaceutical compositions containing nifedipine and process for the preparation thereof
PCT/GB1993/000055 WO1993013773A1 (en) 1992-01-13 1993-01-12 Pharmaceutical compositions containing nifedipine and process for the preparation thereof

Publications (1)

Publication Number Publication Date
DK0620733T3 true DK0620733T3 (da) 2000-07-24

Family

ID=10708487

Family Applications (2)

Application Number Title Priority Date Filing Date
DK93901850T DK0620733T3 (da) 1992-01-13 1993-01-12 Farmaceutiske præparater indeholdende nifedipin samt fremgangsmåde til fremstilling deraf
DK083794A DK83794A (da) 1992-01-13 1994-07-11 Farmaceutiske præparater indeholdende nifedipin og fremgangsmåde til fremstilling heraf

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK083794A DK83794A (da) 1992-01-13 1994-07-11 Farmaceutiske præparater indeholdende nifedipin og fremgangsmåde til fremstilling heraf

Country Status (24)

Country Link
US (1) US5594013A (da)
EP (1) EP0620733B1 (da)
JP (1) JPH07503003A (da)
AT (1) ATE191144T1 (da)
AU (1) AU659529B2 (da)
CA (1) CA2126864A1 (da)
DE (2) DE69328245T2 (da)
DK (2) DK0620733T3 (da)
ES (1) ES2146227T3 (da)
FI (1) FI943316A0 (da)
GB (2) GB9200607D0 (da)
HU (2) HU219338B (da)
IS (1) IS1620B (da)
MY (1) MY110660A (da)
NL (1) NL9320021A (da)
NO (1) NO305223B1 (da)
NZ (1) NZ246374A (da)
PH (1) PH30985A (da)
PL (1) PL170935B1 (da)
PT (1) PT620733E (da)
RU (1) RU2106139C1 (da)
SE (1) SE9402457L (da)
WO (1) WO1993013773A1 (da)
ZA (1) ZA93195B (da)

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US5773025A (en) 1993-09-09 1998-06-30 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems--amorphous drugs
US5455046A (en) * 1993-09-09 1995-10-03 Edward Mendell Co., Inc. Sustained release heterodisperse hydrogel systems for insoluble drugs
US5871776A (en) * 1995-01-31 1999-02-16 Mehta; Atul M. Controlled-release nifedipine
AU7106996A (en) * 1995-09-07 1997-03-27 Fuisz Technologies Ltd. System for rendering substantially non-dissoluble bio-affecting agents bio-available
CO4771151A1 (es) * 1996-01-19 1999-04-30 Rachitzky Falicman Pablo Alberto Procedimiento para la elaboracion de una preparacion farmace utica que contiene nifedipina y la preparacion farmaceutica obtenida mediante el mismo
KR100321489B1 (ko) 1996-07-08 2002-10-09 에드워드 멘델 컴파니 인코포레이티드 고용량의불용성약물용서방성매트릭스
IT1284604B1 (it) * 1996-09-27 1998-05-21 Roberto Valducci Composizioni farmaceutiche a rilascio controllato per somministrazione orale contenenti nifedipina come sostanza attiva
US5922352A (en) * 1997-01-31 1999-07-13 Andrx Pharmaceuticals, Inc. Once daily calcium channel blocker tablet having a delayed release core
US5837379A (en) * 1997-01-31 1998-11-17 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US6056977A (en) * 1997-10-15 2000-05-02 Edward Mendell Co., Inc. Once-a-day controlled release sulfonylurea formulation
US6485748B1 (en) 1997-12-12 2002-11-26 Andrx Pharmaceuticals, Inc. Once daily pharmaceutical tablet having a unitary core
US6264872B1 (en) 1997-12-30 2001-07-24 Kimberly-Clark Worldwide, Inc. Method of forming thin, embossed, textured barrier films
US6969529B2 (en) 2000-09-21 2005-11-29 Elan Pharma International Ltd. Nanoparticulate compositions comprising copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
US6706283B1 (en) 1999-02-10 2004-03-16 Pfizer Inc Controlled release by extrusion of solid amorphous dispersions of drugs
US6168806B1 (en) 1999-03-05 2001-01-02 Fang-Yu Lee Orally administrable nifedipine pellet and process for the preparation thereof
CA2428785C (en) * 2000-11-20 2011-04-26 Henry William Bosch Nanoparticulate compositions comprising a drug and copolymers of vinyl pyrrolidone and vinyl acetate as surface stabilizers
SE0100200D0 (sv) * 2001-01-24 2001-01-24 Astrazeneca Ab New film coating
SI1355633T1 (en) * 2001-12-19 2005-06-30 Astrazeneca Ab NEW FILM COATING containing an ethyl acrylate/methyl methacrylate copolymer and polyvinyl acetate
US6620900B2 (en) * 2002-02-07 2003-09-16 Isp Investments Inc. Proliferous copolymer of vinyl pyrrolidone and vinyl acetate
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
EP1539270A1 (en) * 2002-09-18 2005-06-15 Medtronic Vascular, Inc. Controllable drug releasing gradient coatings for medical devices
US9713592B2 (en) 2005-04-06 2017-07-25 Mallinckrodt Llc Matrix-based pulse release pharmaceutical formulation
WO2007106111A2 (en) * 2005-07-01 2007-09-20 Elan Pharma International Limited Nanoparticulate and controlled release compositions comprising nilvadipine
US20100316711A1 (en) * 2007-10-25 2010-12-16 Bayer Yakuhin ,Ltd. Nifedipine containing opress coated tablet and method of preparing same
RU2629843C1 (ru) * 2016-05-24 2017-09-04 федеральное государственное автономное образовательное учреждение высшего образования Первый Московский государственный медицинский университет имени И.М. Сеченова Министерства здравоохранения Российской Федерации (Сеченовский университет) Способ получения мази нифедипина (варианты)

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DE2400819C2 (de) * 1974-01-09 1982-04-22 Bayer Ag, 5090 Leverkusen Verfahren zur Herstellung fester Zubereitungen von schwerlöslichen Arzneimittelwirkstoffen in feinster Verteilung
GB1579818A (en) * 1977-06-07 1980-11-26 Yamanouchi Pharma Co Ltd Nifedipine-containing solid preparation composition
EP0001247A1 (en) * 1977-09-14 1979-04-04 Kanebo, Ltd. Pharmaceutical preparation containing nifedipine and a method for producing the same.
CA1146866A (en) * 1979-07-05 1983-05-24 Yamanouchi Pharmaceutical Co. Ltd. Process for the production of sustained release pharmaceutical composition of solid medical material
EP0047894B2 (en) * 1980-09-05 1990-09-05 Argus Chemical Corporation Homogeneous storage-stable liquid barium-cadmium-triphosphite stabilizer systems for polyvinyl chloride resins
DE3033919A1 (de) * 1980-09-09 1982-04-22 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen enthaltend nifedipin und verfahren zu ihrer herstellung
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DE3424553A1 (de) * 1984-07-04 1986-01-09 Bayer Ag, 5090 Leverkusen Feste arzneizubereitungen mit dihydropyridinen und verfahren zu ihrer herstellung
IT1178511B (it) * 1984-09-14 1987-09-09 Pharmatec Spa Procedimento per la preparazione di una forma solida per uso orale a base di nifedipina con rilascio
DE3438830A1 (de) * 1984-10-23 1986-04-30 Rentschler Arzneimittel Nifedipin enthaltende darreichungsform und verfahren zu ihrer herstellung
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FR2585174B1 (fr) * 1985-07-16 1987-11-27 Eurofarad Procede de fabrication d'un composant capacitif multicouche a dielectrique ceramique du type cordierite, et composant ainsi obtenu
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SE8601624D0 (sv) * 1986-04-11 1986-04-11 Haessle Ab New pharmaceutical preparations
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IE59540B1 (en) * 1987-01-09 1994-03-09 Elan Corp Sustained release capsule or tablet formulation
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GB8722306D0 (en) * 1987-09-22 1987-10-28 Aps Research Ltd Sustained-release formulation
GB8903328D0 (en) * 1989-02-14 1989-04-05 Ethical Pharma Ltd Nifedipine-containing pharmaceutical compositions and process for the preparation thereof
ATE124864T1 (de) * 1989-03-10 1995-07-15 Yamanouchi Pharma Co Ltd Die wirkstoffabgabe steuerndes überzugsmaterial für lang wirksame formulierungen.
HU203041B (en) * 1989-03-14 1991-05-28 Egyt Gyogyszervegyeszeti Gyar Process for producing pharmaceutical compositions of controlled releasing factor containing nifedipin
JPH0729926B2 (ja) * 1989-07-25 1995-04-05 大塚製薬株式会社 易吸収性製剤用組成物

Also Published As

Publication number Publication date
PT620733E (pt) 2000-08-31
RU94035739A (ru) 1996-09-20
PL300638A1 (en) 1994-03-21
NO305223B1 (no) 1999-04-26
PH30985A (en) 1997-12-23
JPH07503003A (ja) 1995-03-30
NZ246374A (en) 1995-07-26
RU2106139C1 (ru) 1998-03-10
DE69328245D1 (de) 2000-05-04
US5594013A (en) 1997-01-14
GB2277872B (en) 1995-10-04
DE69328245T2 (de) 2000-10-12
GB9200607D0 (en) 1992-03-11
HU210539A9 (en) 1995-05-29
NL9320021A (nl) 1995-06-01
AU3263693A (en) 1993-08-03
SE9402457D0 (sv) 1994-07-12
PL170935B1 (pl) 1997-02-28
WO1993013773A1 (en) 1993-07-22
GB9413101D0 (en) 1994-08-31
MY110660A (en) 1999-01-30
FI943316A (fi) 1994-07-12
SE9402457L (sv) 1994-09-12
ZA93195B (en) 1993-08-16
ATE191144T1 (de) 2000-04-15
DE4390075T1 (de) 1994-12-01
CA2126864A1 (en) 1993-07-22
HU219338B (en) 2001-03-28
DK83794A (da) 1994-07-11
GB2277872A (en) 1994-11-16
IS1620B (is) 1996-10-18
NO942622L (no) 1994-07-12
EP0620733A1 (en) 1994-10-26
HU9401850D0 (en) 1994-09-28
FI943316A0 (fi) 1994-07-12
NO942622D0 (no) 1994-07-12
IS3966A (is) 1993-07-14
HUT67426A (en) 1995-04-28
ES2146227T3 (es) 2000-08-01
AU659529B2 (en) 1995-05-18
EP0620733B1 (en) 2000-03-29

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