NL8803196A - Nieuwe op 17alfa gesubstitueerde 17beta-hydroxy-19-norsteroiden, werkwijze voor de bereiding daarvan, hun toepassing als geneesmiddelen en farmaceutische preparaten die ze bevatten. - Google Patents
Nieuwe op 17alfa gesubstitueerde 17beta-hydroxy-19-norsteroiden, werkwijze voor de bereiding daarvan, hun toepassing als geneesmiddelen en farmaceutische preparaten die ze bevatten. Download PDFInfo
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- NL8803196A NL8803196A NL8803196A NL8803196A NL8803196A NL 8803196 A NL8803196 A NL 8803196A NL 8803196 A NL8803196 A NL 8803196A NL 8803196 A NL8803196 A NL 8803196A NL 8803196 A NL8803196 A NL 8803196A
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- Netherlands
- Prior art keywords
- formula
- hydroxy
- compound
- compounds
- dimethylamino
- Prior art date
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Classifications
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- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
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- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Diabetes (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Endocrinology (AREA)
- Emergency Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Vascular Medicine (AREA)
- Urology & Nephrology (AREA)
- Anesthesiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Child & Adolescent Psychology (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8718376 | 1987-12-30 | ||
| FR8718376A FR2625505B2 (fr) | 1981-01-09 | 1987-12-30 | Nouveaux derives steroides substitues en 11beta leur procede de preparation et leur application comme medicaments et les compositions pharmaceutiques les renfermant |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL8803196A true NL8803196A (nl) | 1989-07-17 |
Family
ID=9358447
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8803196A NL8803196A (nl) | 1987-12-30 | 1988-12-29 | Nieuwe op 17alfa gesubstitueerde 17beta-hydroxy-19-norsteroiden, werkwijze voor de bereiding daarvan, hun toepassing als geneesmiddelen en farmaceutische preparaten die ze bevatten. |
Country Status (14)
| Country | Link |
|---|---|
| US (1) | US5006518A (enExample) |
| JP (1) | JP2785023B2 (enExample) |
| AT (1) | AT396787B (enExample) |
| BE (1) | BE1004905A4 (enExample) |
| CA (1) | CA1303025C (enExample) |
| CH (1) | CH676852A5 (enExample) |
| DE (1) | DE3844408C2 (enExample) |
| ES (1) | ES2012197A6 (enExample) |
| GB (1) | GB2213484B (enExample) |
| GR (1) | GR880100868A (enExample) |
| IT (1) | IT1235358B (enExample) |
| LU (1) | LU87417A1 (enExample) |
| NL (1) | NL8803196A (enExample) |
| SE (1) | SE503267C2 (enExample) |
Families Citing this family (29)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2654337B1 (fr) * | 1989-11-15 | 1994-08-05 | Roussel Uclaf | Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant. |
| DE4042004A1 (de) * | 1990-12-22 | 1992-06-25 | Schering Ag | 14(beta)-h-, 14- u. 15-en-11(beta)-aryl-4-estrene |
| EP0496520A1 (en) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Novel bone acting agents |
| US6407082B1 (en) * | 1996-09-13 | 2002-06-18 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of a vitamin D compound |
| JP3862295B2 (ja) * | 1993-09-30 | 2006-12-27 | 独立行政法人理化学研究所 | 抗肥満剤 |
| DK0683172T3 (da) * | 1994-05-19 | 1998-03-30 | Akzo Nobel Nv | 11,21-bisphenyl-19-norpregnanderivater |
| US5780220A (en) * | 1994-05-19 | 1998-07-14 | Trustees Of The University Of Pennsylvania | Methods and compositions for inhibiting HIV replication |
| US5639598A (en) * | 1994-05-19 | 1997-06-17 | The Trustees Of The University Of Pennsylvania | Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions |
| US6765002B2 (en) | 2000-03-21 | 2004-07-20 | Gustavo Rodriguez | Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium |
| US6034074A (en) | 1996-09-13 | 2000-03-07 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of a Vitamin D compound |
| US6028064A (en) | 1996-09-13 | 2000-02-22 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of progestin products |
| US6511970B1 (en) | 1996-09-13 | 2003-01-28 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium |
| DE19706061A1 (de) * | 1997-02-07 | 1998-08-13 | Schering Ag | Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette |
| US20010044431A1 (en) * | 2000-03-21 | 2001-11-22 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
| JP2001301596A (ja) | 2000-04-19 | 2001-10-31 | Sumitomo Denko Brake Systems Kk | 車両用液圧ブレーキシステムの制御方法 |
| MX2008016571A (es) * | 2007-05-01 | 2009-03-09 | Sicor Inc | Proceso para preparar drospirenona y su intermediarios. |
| WO2011150209A1 (en) | 2010-05-26 | 2011-12-01 | Corcept Therapeutics, Inc. | Treatment of muscular dystrophy |
| JP6821582B2 (ja) | 2015-03-02 | 2021-01-27 | コーセプト セラピューティクス， インコーポレイテッド | Ａｃｔｈ分泌腫瘍を処置するための糖質コルチコイドレセプターアンタゴニストおよびソマトスタチンアナログの使用 |
| JP6754533B2 (ja) | 2015-03-30 | 2020-09-16 | コーセプト セラピューティクス， インコーポレイテッド | 副腎機能不全を処置するための糖質コルチコイドと組み合わせた糖質コルチコイドレセプターアンタゴニストの使用 |
| MX383318B (es) | 2015-08-13 | 2025-03-13 | Corcept Therapeutics Inc | Metodo para diagnosticar de manera diferencial el sindrome de cushing dependiente de la corticotropina. |
| JP6906525B2 (ja) * | 2015-12-23 | 2021-07-21 | オリック ファーマシューティカルズ，インク． | グルココルチコイド受容体の阻害剤 |
| US11110103B2 (en) | 2015-12-23 | 2021-09-07 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
| WO2017112909A1 (en) | 2015-12-23 | 2017-06-29 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
| JP6765443B2 (ja) | 2016-01-19 | 2020-10-07 | コーセプト セラピューティクス， インコーポレイテッド | 異所性クッシング症候群の鑑別診断 |
| US9943505B2 (en) | 2016-09-09 | 2018-04-17 | Corcept Therapeutics, Inc. | Glucocorticoid receptor modulators to treat pancreatic cancer |
| PT3523315T (pt) | 2016-10-07 | 2021-04-29 | Oric Pharmaceuticals Inc | Inibidor de recetor de glucocorticoide |
| AU2018244928B2 (en) | 2017-03-31 | 2023-10-19 | Corcept Therapeutics, Inc. | Glucocorticoid receptor modulators to treat cervical cancer |
| WO2018236749A2 (en) | 2017-06-20 | 2018-12-27 | Corcept Therapeutics, Inc. | Methods of treating neuroepithelial tumors using selective glucocorticoid receptor modulators |
| EP4263807A2 (en) | 2020-12-18 | 2023-10-25 | Instil Bio (Uk) Limited | Processing of tumor infiltrating lymphocytes |
Family Cites Families (15)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2377418A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments |
| ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
| FR2528434B1 (fr) * | 1982-06-11 | 1985-07-19 | Roussel Uclaf | Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament |
| EP0110434B1 (fr) * | 1981-01-09 | 1986-10-29 | Roussel-Uclaf | Nouveaux produits intermédiaires stéroides substitués en 11-beta et procédé de préparation de ces produits |
| DE3461090D1 (en) * | 1983-02-18 | 1986-12-04 | Schering Ag | 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them |
| FR2549067B1 (fr) * | 1983-06-14 | 1985-12-27 | Roussel Uclaf | Derives estradieniques radioactifs marques au tritium, leur procede de preparation et leur application pour l'etude et le dosage radio-immunologique de steroides dans les fluides biologiques |
| US4780461A (en) * | 1983-06-15 | 1988-10-25 | Schering Aktiengesellschaft | 13α-alkyl-gonanes, their production, and pharmaceutical preparations containing same |
| ES8502612A1 (es) * | 1983-06-15 | 1985-02-01 | Schering Ag | Procedimiento para la preparacion de 13a-alquilgonanos |
| DE3347126A1 (de) * | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
| FR2566779B2 (fr) * | 1984-06-29 | 1987-03-06 | Roussel Uclaf | Nouveaux derives steroides substitues en 11b, leur procede de preparation et leur application comme medicaments |
| DE3506785A1 (de) * | 1985-02-22 | 1986-08-28 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 11ss-n,n-dimethylaminophenyl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
| DE3619413C2 (de) * | 1986-06-10 | 2000-04-06 | Schering Ag | 9alpha, 10alpha-Methylen-Estrene, deren Herstellung und diese enthaltende pharmazeutische Präparate |
| DE3625315A1 (de) * | 1986-07-25 | 1988-01-28 | Schering Ag | 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate |
| US4774236A (en) * | 1986-09-17 | 1988-09-27 | Research Triangle Institute | 17α-(substituted-methyl)-17β-hydroxy/esterified hydroxy steroids and pharmaceutical compositions containing them |
| IE60780B1 (en) * | 1987-01-23 | 1994-08-10 | Akzo Nv | New 11-aryl steroid derivatives |
-
1988
- 1988-12-28 JP JP63329538A patent/JP2785023B2/ja not_active Expired - Fee Related
- 1988-12-28 BE BE8801441A patent/BE1004905A4/fr not_active IP Right Cessation
- 1988-12-29 NL NL8803196A patent/NL8803196A/nl not_active Application Discontinuation
- 1988-12-29 AT AT0318788A patent/AT396787B/de not_active IP Right Cessation
- 1988-12-29 SE SE8804692A patent/SE503267C2/sv not_active IP Right Cessation
- 1988-12-29 CH CH4860/88A patent/CH676852A5/fr not_active IP Right Cessation
- 1988-12-29 ES ES8804011A patent/ES2012197A6/es not_active Expired - Fee Related
- 1988-12-29 GR GR880100868A patent/GR880100868A/el unknown
- 1988-12-29 LU LU87417A patent/LU87417A1/fr unknown
- 1988-12-29 IT IT8848730A patent/IT1235358B/it active
- 1988-12-29 CA CA000587227A patent/CA1303025C/fr not_active Expired - Lifetime
- 1988-12-30 GB GB8830380A patent/GB2213484B/en not_active Expired - Lifetime
- 1988-12-30 US US07/292,475 patent/US5006518A/en not_active Expired - Fee Related
- 1988-12-30 DE DE3844408A patent/DE3844408C2/de not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATA318788A (de) | 1993-04-15 |
| JPH01213296A (ja) | 1989-08-28 |
| AT396787B (de) | 1993-11-25 |
| IT1235358B (it) | 1992-06-30 |
| IT8848730A0 (it) | 1988-12-29 |
| GR880100868A (el) | 1994-03-31 |
| ES2012197A6 (es) | 1990-03-01 |
| JP2785023B2 (ja) | 1998-08-13 |
| US5006518A (en) | 1991-04-09 |
| SE503267C2 (sv) | 1996-04-29 |
| DE3844408A1 (de) | 1989-07-13 |
| GB8830380D0 (en) | 1989-03-01 |
| GB2213484B (en) | 1991-10-09 |
| SE8804692D0 (sv) | 1988-12-29 |
| CH676852A5 (enExample) | 1991-03-15 |
| BE1004905A4 (fr) | 1993-02-23 |
| DE3844408C2 (de) | 2001-07-26 |
| CA1303025C (fr) | 1992-06-09 |
| LU87417A1 (fr) | 1989-06-14 |
| SE8804692L (sv) | 1989-07-01 |
| GB2213484A (en) | 1989-08-16 |
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Free format text: HOECHST ROUSSEL VET S.A. |
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| BV | The patent application has lapsed |