IT8848730A0 - Derivati 17beta-oh 19-nor steroidei sostituiti in 17alfa, procedimento di preparazione, loro impiego come medicamenti e composizioni farmaceutiche che li compongono - Google Patents
Derivati 17beta-oh 19-nor steroidei sostituiti in 17alfa, procedimento di preparazione, loro impiego come medicamenti e composizioni farmaceutiche che li compongonoInfo
- Publication number
- IT8848730A0 IT8848730A0 IT8848730A IT4873088A IT8848730A0 IT 8848730 A0 IT8848730 A0 IT 8848730A0 IT 8848730 A IT8848730 A IT 8848730A IT 4873088 A IT4873088 A IT 4873088A IT 8848730 A0 IT8848730 A0 IT 8848730A0
- Authority
- IT
- Italy
- Prior art keywords
- 17alfa
- 17beta
- compose
- medicines
- pharmaceutical compositions
- Prior art date
Links
- VVUQRXPUVKXAIO-XFUVECHXSA-N 19-nor-5-androstenediol Chemical compound C1[C@@H](O)CC[C@@H]2[C@H]3CC[C@](C)([C@H](CC4)O)[C@@H]4[C@@H]3CC=C21 VVUQRXPUVKXAIO-XFUVECHXSA-N 0.000 title 1
- 239000003814 drug Substances 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/04—Anorexiants; Antiobesity agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/06—Antihyperlipidemics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR8718376A FR2625505B2 (fr) | 1981-01-09 | 1987-12-30 | Nouveaux derives steroides substitues en 11beta leur procede de preparation et leur application comme medicaments et les compositions pharmaceutiques les renfermant |
Publications (2)
Publication Number | Publication Date |
---|---|
IT8848730A0 true IT8848730A0 (it) | 1988-12-29 |
IT1235358B IT1235358B (it) | 1992-06-30 |
Family
ID=9358447
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
IT8848730A IT1235358B (it) | 1987-12-30 | 1988-12-29 | Derivati 17beta-oh 19-nor steroidei sostituiti in 17alfa, procedimento di preparazione, loro impiego come medicamenti e composizioni farmaceutiche che li compongono |
Country Status (14)
Country | Link |
---|---|
US (1) | US5006518A (it) |
JP (1) | JP2785023B2 (it) |
AT (1) | AT396787B (it) |
BE (1) | BE1004905A4 (it) |
CA (1) | CA1303025C (it) |
CH (1) | CH676852A5 (it) |
DE (1) | DE3844408C2 (it) |
ES (1) | ES2012197A6 (it) |
GB (1) | GB2213484B (it) |
GR (1) | GR880100868A (it) |
IT (1) | IT1235358B (it) |
LU (1) | LU87417A1 (it) |
NL (1) | NL8803196A (it) |
SE (1) | SE503267C2 (it) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2654337B1 (fr) * | 1989-11-15 | 1994-08-05 | Roussel Uclaf | Nouvelles microspheres injectables biodegradables procede de preparation et suspensions injectables les renfermant. |
DE4042004A1 (de) * | 1990-12-22 | 1992-06-25 | Schering Ag | 14(beta)-h-, 14- u. 15-en-11(beta)-aryl-4-estrene |
EP0496520A1 (en) * | 1991-01-22 | 1992-07-29 | Merck & Co. Inc. | Novel bone acting agents |
US6407082B1 (en) * | 1996-09-13 | 2002-06-18 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of a vitamin D compound |
JP3862295B2 (ja) * | 1993-09-30 | 2006-12-27 | 独立行政法人理化学研究所 | 抗肥満剤 |
US5639598A (en) * | 1994-05-19 | 1997-06-17 | The Trustees Of The University Of Pennsylvania | Method and kit for identification of antiviral agents capable of abrogating HIV Vpr-Rip-1 binding interactions |
US5780220A (en) * | 1994-05-19 | 1998-07-14 | Trustees Of The University Of Pennsylvania | Methods and compositions for inhibiting HIV replication |
ZA953976B (en) * | 1994-05-19 | 1996-01-19 | Akzo Nobel Nv | 11,21-bisphenyl-19-norpregnane derivatives |
US6034074A (en) | 1996-09-13 | 2000-03-07 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of a Vitamin D compound |
US6028064A (en) * | 1996-09-13 | 2000-02-22 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of progestin products |
US6511970B1 (en) | 1996-09-13 | 2003-01-28 | New Life Pharmaceuticals Inc. | Prevention of ovarian cancer by administration of products that induce transforming growth factor-beta and/or apoptosis in the ovarian epithelium |
US6765002B2 (en) | 2000-03-21 | 2004-07-20 | Gustavo Rodriguez | Prevention of ovarian cancer by administration of products that induce transforming growth factor-β and/or apoptosis in the ovarian epithelium |
DE19706061A1 (de) | 1997-02-07 | 1998-08-13 | Schering Ag | Antigestagen wirksame Steroide mit fluorierter 17alpha-Alkylkette |
US20010044431A1 (en) * | 2000-03-21 | 2001-11-22 | Rodriguez Gustavo C. | Prevention of ovarian cancer by administration of products that induce biologic effects in the ovarian epithelium |
JP2001301596A (ja) | 2000-04-19 | 2001-10-31 | Sumitomo Denko Brake Systems Kk | 車両用液圧ブレーキシステムの制御方法 |
EP2253641A2 (en) * | 2007-05-01 | 2010-11-24 | Sicor, Inc. | A process for preparing drospirenone and intermediate thereof |
US11103514B2 (en) | 2010-05-26 | 2021-08-31 | Corcept Therapeutics, Inc. | Treatment of muscular dystrophy |
CN107530435A (zh) | 2015-03-02 | 2018-01-02 | 科赛普特治疗学股份有限公司 | 使用糖皮质激素受体拮抗剂和生长抑素治疗acth分泌型肿瘤 |
AU2016243625B2 (en) | 2015-03-30 | 2020-09-10 | Corcept Therapeutics, Inc. | Use of glucocorticoid receptor antagonists in combination with glucocorticoids to treat adrenal insufficiency |
MX2018001803A (es) | 2015-08-13 | 2018-05-16 | Corcept Therapeutics Inc | Metodo para disgnosticar de manera diferencial el sindrome de cushing dependiente de la corticotropina. |
CA3009525A1 (en) | 2015-12-23 | 2017-06-29 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
US11110103B2 (en) | 2015-12-23 | 2021-09-07 | Oric Pharmaceuticals, Inc. | Inhibitors of glucocorticoid receptor |
EP3394078A4 (en) * | 2015-12-23 | 2019-11-27 | Oric Pharmaceuticals, Inc. | GLUCOCORTICOID RECEPTOR INHIBITORS |
JP6765443B2 (ja) | 2016-01-19 | 2020-10-07 | コーセプト セラピューティクス, インコーポレイテッド | 異所性クッシング症候群の鑑別診断 |
PL3523315T3 (pl) | 2016-10-07 | 2021-10-18 | Oric Pharmaceuticals, Inc. | Inhibitor receptora glukokortykoidowego |
AU2021400069A1 (en) | 2020-12-18 | 2023-07-06 | Instil Bio (Uk) Limited | Processing of tumor infiltrating lymphocytes |
Family Cites Families (15)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR2377418A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides 4,9-dieniques 11b-substitues, leur procede de preparation et leur application comme medicaments |
ATE23167T1 (de) * | 1981-01-09 | 1986-11-15 | Roussel Uclaf | In stellung 11 substituierte steroidzwischenprodukte und verfahren zu ihrer herstellung. |
ZA8231B (en) * | 1981-01-09 | 1982-11-24 | Roussel Uclaf | New 11 -substituted steroid derivatives, their preparation, their use as medicaments, the compositions containing them and the new intermediates thus obtained |
FR2528434B1 (fr) * | 1982-06-11 | 1985-07-19 | Roussel Uclaf | Nouveaux 19-nor steroides substitues en 11b et eventuellement en 2, leur procede de preparation et leur application comme medicament |
DE3461090D1 (en) * | 1983-02-18 | 1986-12-04 | Schering Ag | 11-beta-aryl-estradienes, process for their preparation and pharmaceutical compositions containing them |
FR2549067B1 (fr) * | 1983-06-14 | 1985-12-27 | Roussel Uclaf | Derives estradieniques radioactifs marques au tritium, leur procede de preparation et leur application pour l'etude et le dosage radio-immunologique de steroides dans les fluides biologiques |
ES8502612A1 (es) * | 1983-06-15 | 1985-02-01 | Schering Ag | Procedimiento para la preparacion de 13a-alquilgonanos |
US4780461A (en) * | 1983-06-15 | 1988-10-25 | Schering Aktiengesellschaft | 13α-alkyl-gonanes, their production, and pharmaceutical preparations containing same |
DE3347126A1 (de) * | 1983-12-22 | 1985-07-11 | Schering AG, 1000 Berlin und 4709 Bergkamen | 11ss-aryl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
FR2566779B2 (fr) * | 1984-06-29 | 1987-03-06 | Roussel Uclaf | Nouveaux derives steroides substitues en 11b, leur procede de preparation et leur application comme medicaments |
DE3506785A1 (de) * | 1985-02-22 | 1986-08-28 | Schering AG, Berlin und Bergkamen, 1000 Berlin | 11ss-n,n-dimethylaminophenyl-estradiene, deren herstellung und diese enthaltende pharmazeutische praeparate |
DE3619413C2 (de) * | 1986-06-10 | 2000-04-06 | Schering Ag | 9alpha, 10alpha-Methylen-Estrene, deren Herstellung und diese enthaltende pharmazeutische Präparate |
DE3625315A1 (de) * | 1986-07-25 | 1988-01-28 | Schering Ag | 11ss-(4-isopropenylphenyl)-estra-4,9-diene, deren herstellung und diese enthaltende pharmazeutische praeparate |
US4774236A (en) * | 1986-09-17 | 1988-09-27 | Research Triangle Institute | 17α-(substituted-methyl)-17β-hydroxy/esterified hydroxy steroids and pharmaceutical compositions containing them |
IE60780B1 (en) * | 1987-01-23 | 1994-08-10 | Akzo Nv | New 11-aryl steroid derivatives |
-
1988
- 1988-12-28 JP JP63329538A patent/JP2785023B2/ja not_active Expired - Fee Related
- 1988-12-28 BE BE8801441A patent/BE1004905A4/fr not_active IP Right Cessation
- 1988-12-29 CA CA000587227A patent/CA1303025C/fr not_active Expired - Lifetime
- 1988-12-29 GR GR880100868A patent/GR880100868A/el unknown
- 1988-12-29 ES ES8804011A patent/ES2012197A6/es not_active Expired - Fee Related
- 1988-12-29 NL NL8803196A patent/NL8803196A/nl not_active Application Discontinuation
- 1988-12-29 SE SE8804692A patent/SE503267C2/sv not_active IP Right Cessation
- 1988-12-29 AT AT0318788A patent/AT396787B/de not_active IP Right Cessation
- 1988-12-29 IT IT8848730A patent/IT1235358B/it active
- 1988-12-29 CH CH4860/88A patent/CH676852A5/fr not_active IP Right Cessation
- 1988-12-29 LU LU87417A patent/LU87417A1/fr unknown
- 1988-12-30 DE DE3844408A patent/DE3844408C2/de not_active Expired - Lifetime
- 1988-12-30 GB GB8830380A patent/GB2213484B/en not_active Expired - Lifetime
- 1988-12-30 US US07/292,475 patent/US5006518A/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
AT396787B (de) | 1993-11-25 |
CH676852A5 (it) | 1991-03-15 |
US5006518A (en) | 1991-04-09 |
BE1004905A4 (fr) | 1993-02-23 |
ATA318788A (de) | 1993-04-15 |
GB2213484B (en) | 1991-10-09 |
JP2785023B2 (ja) | 1998-08-13 |
DE3844408C2 (de) | 2001-07-26 |
SE8804692L (sv) | 1989-07-01 |
LU87417A1 (fr) | 1989-06-14 |
JPH01213296A (ja) | 1989-08-28 |
CA1303025C (fr) | 1992-06-09 |
GR880100868A (el) | 1994-03-31 |
SE503267C2 (sv) | 1996-04-29 |
SE8804692D0 (sv) | 1988-12-29 |
GB2213484A (en) | 1989-08-16 |
NL8803196A (nl) | 1989-07-17 |
DE3844408A1 (de) | 1989-07-13 |
GB8830380D0 (en) | 1989-03-01 |
ES2012197A6 (es) | 1990-03-01 |
IT1235358B (it) | 1992-06-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
IT8848730A0 (it) | Derivati 17beta-oh 19-nor steroidei sostituiti in 17alfa, procedimento di preparazione, loro impiego come medicamenti e composizioni farmaceutiche che li compongono | |
IT8848714A0 (it) | Derivati di adenosina, composizioni farmaceutiche che li contengono erelativo procedimento di preparazione ed appplicazione | |
IT1203806B (it) | Derivati del tiazolo,loro preparazione e composizioni farmaceutiche che li contengono | |
IT1224226B (it) | Derivati benzofuranici procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che li comprendono | |
IT8847871A0 (it) | Ne e loro impiego come medicamenti derivati peptidici,loro preparazio- | |
IT1205665B (it) | Derivati 1-(idrossistiril)-5h2,3-benzodiazepinici,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
KR880700814A (ko) | 아미노글리코사이드 스테로이드, 이의 제조방법, 이의 용도 및 이를 함유하는 약제학적 조성물 | |
KR880700815A (ko) | 아미노글리코사이드 스테로이드, 그의 제조방법, 그의 용도 및 이를 함유하는 약제학적 조성물 | |
IT8667976A0 (it) | Derivati teofillinmetilditiolanici e teofillinmetilditianici procedimento per la loro preparazione e composizioni farmaceutiche che li comprendono | |
IT8248970A0 (it) | Derivati xantinici, procedimento per la loro preparazione, composizione farmaceutiche che li contengono e loro impiego terapeutico | |
IT1193590B (it) | Derivati amino-alchil-solfonici,procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
IT9021305A0 (it) | Derivati aminopropanolici, procedimenti per la loro preparazione e composizioni farmaceutiche che li contengono | |
IT1227456B (it) | Nuovi alcossi derivati di ginkgolidi, loro preparazione e composizioni terapeutiche che li contengono | |
IT8948610A0 (it) | Derivati ciclici e loro metaboliti, loro preparazione e composizioni farmaceutiche che li contengono | |
IT1184285B (it) | Derivati steroidei sostituiti in posizione 11-beta,procedimento per la loro preparazione e loro applicazione come medicamenti | |
IT1129305B (it) | Derivati di 1,2,4 ossadiazolin 5 one procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
ITMI910846A1 (it) | Derivati di flavoni, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono | |
IT1200079B (it) | Derivati della naftossazina, loro preparazione, loro applicazione come medicamenti e composizioni farmaceutiche che li contengono | |
IT1243751B (it) | Derivati di corticosteroidi, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. | |
IT1219567B (it) | Derivati di forskolina,loro procedimento ed intermedi di preparazione,loro applicazione in qualita' di medicamenti e composizioni farmaceutiche che li contengono | |
IT8823183A0 (it) | Derivati diossazocinici, loro preparazione e composizioni che li contengono | |
IT1216120B (it) | Derivati n_cicloalchilaminoetilbenzamidici, loro preparazione e composizioni farmaceutiche che li contengono. | |
ITFI920134A1 (it) | Derivati 7-neopentil xantinici, loro preparazione e composizioni farmaceutiche che li contengono | |
IT1188188B (it) | Derivati di 6-aminometil-furo-(3,4-c)-piridina,loro preparazione e composizioni farmaceutiche contenenti gli stessi | |
IT8520483A0 (it) | Derivati di apovincaminolo, procedimento per la loro preparazione e composizioni farmaceutiche che li contengono. |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19951127 |