ATE23167T1 - In stellung 11 substituierte steroidzwischenprodukte und verfahren zu ihrer herstellung. - Google Patents
In stellung 11 substituierte steroidzwischenprodukte und verfahren zu ihrer herstellung.Info
- Publication number
- ATE23167T1 ATE23167T1 AT83201391T AT83201391T ATE23167T1 AT E23167 T1 ATE23167 T1 AT E23167T1 AT 83201391 T AT83201391 T AT 83201391T AT 83201391 T AT83201391 T AT 83201391T AT E23167 T1 ATE23167 T1 AT E23167T1
- Authority
- AT
- Austria
- Prior art keywords
- cpds
- treat
- progestomimetic
- opt
- alpha
- Prior art date
Links
- 239000013067 intermediate product Substances 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
- 150000003431 steroids Chemical class 0.000 title 1
- 239000000543 intermediate Substances 0.000 abstract 2
- 230000000962 progestomimetic effect Effects 0.000 abstract 2
- 208000002874 Acne Vulgaris Diseases 0.000 abstract 1
- 206010001928 Amenorrhoea Diseases 0.000 abstract 1
- 201000001320 Atherosclerosis Diseases 0.000 abstract 1
- 206010004446 Benign prostatic hyperplasia Diseases 0.000 abstract 1
- 206010020112 Hirsutism Diseases 0.000 abstract 1
- 206010020772 Hypertension Diseases 0.000 abstract 1
- 229930194542 Keto Natural products 0.000 abstract 1
- 206010028980 Neoplasm Diseases 0.000 abstract 1
- 208000008589 Obesity Diseases 0.000 abstract 1
- 208000001132 Osteoporosis Diseases 0.000 abstract 1
- 206010060862 Prostate cancer Diseases 0.000 abstract 1
- 208000004403 Prostatic Hyperplasia Diseases 0.000 abstract 1
- 208000000236 Prostatic Neoplasms Diseases 0.000 abstract 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 abstract 1
- 206010000496 acne Diseases 0.000 abstract 1
- 230000032683 aging Effects 0.000 abstract 1
- 230000001548 androgenic effect Effects 0.000 abstract 1
- 208000007502 anemia Diseases 0.000 abstract 1
- 230000002280 anti-androgenic effect Effects 0.000 abstract 1
- 229940124558 contraceptive agent Drugs 0.000 abstract 1
- 239000003433 contraceptive agent Substances 0.000 abstract 1
- 230000001419 dependent effect Effects 0.000 abstract 1
- 230000000994 depressogenic effect Effects 0.000 abstract 1
- 206010012601 diabetes mellitus Diseases 0.000 abstract 1
- 239000003862 glucocorticoid Substances 0.000 abstract 1
- 230000003054 hormonal effect Effects 0.000 abstract 1
- 239000005556 hormone Substances 0.000 abstract 1
- 229940088597 hormone Drugs 0.000 abstract 1
- 125000001183 hydrocarbyl group Chemical group 0.000 abstract 1
- 230000036039 immunity Effects 0.000 abstract 1
- 206010022437 insomnia Diseases 0.000 abstract 1
- 125000000468 ketone group Chemical group 0.000 abstract 1
- 230000000938 luteal effect Effects 0.000 abstract 1
- 235000020824 obesity Nutrition 0.000 abstract 1
- 150000002923 oximes Chemical class 0.000 abstract 1
- 201000004240 prostatic hypertrophy Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J71/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton is condensed with a heterocyclic ring
- C07J71/0005—Oxygen-containing hetero ring
- C07J71/001—Oxiranes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J21/00—Normal steroids containing carbon, hydrogen, halogen or oxygen having an oxygen-containing hetero ring spiro-condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J21/005—Ketals
- C07J21/006—Ketals at position 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0005—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring the nitrogen atom being directly linked to the cyclopenta(a)hydro phenanthrene skeleton
- C07J41/0016—Oximes
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J41/00—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring
- C07J41/0033—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005
- C07J41/0077—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom
- C07J41/0083—Normal steroids containing one or more nitrogen atoms not belonging to a hetero ring not covered by C07J41/0005 substituted in position 11-beta by a carbon atom, further substituted by a group comprising at least one further carbon atom substituted in position 11-beta by an optionally substituted phenyl group not further condensed with other rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J43/00—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton
- C07J43/003—Normal steroids having a nitrogen-containing hetero ring spiro-condensed or not condensed with the cyclopenta(a)hydrophenanthrene skeleton not condensed
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J51/00—Normal steroids with unmodified cyclopenta(a)hydrophenanthrene skeleton not provided for in groups C07J1/00 - C07J43/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J63/00—Steroids in which the cyclopenta(a)hydrophenanthrene skeleton has been modified by expansion of only one ring by one or two atoms
- C07J63/008—Expansion of ring D by one atom, e.g. D homo steroids
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07J—STEROIDS
- C07J7/00—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms
- C07J7/0005—Normal steroids containing carbon, hydrogen, halogen or oxygen substituted in position 17 beta by a chain of two carbon atoms not substituted in position 21
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Steroid Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR8100272A FR2497807A1 (fr) | 1981-01-09 | 1981-01-09 | Nouveaux derives steroides substitues en 11b, leur proc ede de preparation et leur application comme medicament |
| EP83201391A EP0110434B1 (de) | 1981-01-09 | 1982-01-08 | In Stellung 11 substituierte Steroidzwischenprodukte und Verfahren zu ihrer Herstellung |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE23167T1 true ATE23167T1 (de) | 1986-11-15 |
Family
ID=26088603
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT83201391T ATE23167T1 (de) | 1981-01-09 | 1982-01-08 | In stellung 11 substituierte steroidzwischenprodukte und verfahren zu ihrer herstellung. |
Country Status (2)
| Country | Link |
|---|---|
| EP (1) | EP0110434B1 (de) |
| AT (1) | ATE23167T1 (de) |
Families Citing this family (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2785023B2 (ja) * | 1987-12-30 | 1998-08-13 | ルセル―ユクラフ | １７α位置を置換された１７β―ＯＨ―１９―ノルステロイドの新誘導体、その製造方法、その薬剤としての使用及びそれを含有する製薬組成物 |
| EP0411733B1 (de) * | 1989-08-04 | 1998-10-21 | Schering Aktiengesellschaft | 11 Beta-Aryl-gona-4,9-dien-3-one |
| DE4008584A1 (de) * | 1990-03-15 | 1991-09-26 | Schering Ag | Verfahren zur herstellung von zwischenprodukten fuer die antigestagensynthese (onapristonsynthese) |
| US5407928A (en) * | 1990-08-15 | 1995-04-18 | Schering Aktiengesellschaft | 11β-aryl-gona-4,9-dien-3-ones |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2377417A1 (fr) * | 1977-01-13 | 1978-08-11 | Roussel Uclaf | Nouveaux derives steroides substitues en 11b, ainsi que leur procede de preparation |
-
1982
- 1982-01-08 AT AT83201391T patent/ATE23167T1/de not_active IP Right Cessation
- 1982-01-08 EP EP83201391A patent/EP0110434B1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| EP0110434A1 (de) | 1984-06-13 |
| EP0110434B1 (de) | 1986-10-29 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| IE52595B1 (en) | New steroid derivatives substituted at position 11beta,process and intermediates for preparing them,their use as medicaments and the compositions containing them | |
| US3135743A (en) | Steroido[2. 3-d]isoxazoles and preparation thereof | |
| Penov Gasi et al. | An overview of partial synthesis and transformations of secosteroids | |
| GB2078750A (en) | 10-(1,2-propadienyl)-steroids | |
| ATE23167T1 (de) | In stellung 11 substituierte steroidzwischenprodukte und verfahren zu ihrer herstellung. | |
| US3431258A (en) | Steroidal 4-hydroxy-2-butenoic acid lactones | |
| US3445489A (en) | 9beta,10alpha-steroids,intermediates therefor and pharmaceutical preparations containing these compounds as an active ingredient | |
| US2874173A (en) | Estrone compounds | |
| US2838492A (en) | 6-fluoro steroids | |
| US3849402A (en) | 19-oxygenated and 19-nor delta8(14)-steroid compounds | |
| WALL et al. | Steroidal Sapogenins. LIII. Permanganate-Periodate Oxidation of Pseudosapogenins2 | |
| Clinton et al. | D-Homosteroids. I. Derivatives of D-Homoetiocholan-3α-ol-11, 17a-dione | |
| US3280157A (en) | Peroxy steroids and methods for their manufacture | |
| US3510556A (en) | 17alpha-ethers of 16-methylene-19-nor-progesterones | |
| US3461118A (en) | 3beta-tetrahydrofuranyloxy - and 3beta-tetrahydropyranyloxyestra - 4,9(10) - dienes and -4,9(10),11-trienes,their preparation and intermediates thereof | |
| US3194832A (en) | 18-nor-d-homo-steroids | |
| Johns et al. | Synthesis and reactions of 17. beta.-oxygenated 16. alpha., 17-cyclopropylandrostanes | |
| NAMBARA et al. | Studies on Metabolism of 3-Desoxyestrone. III. Synthesis of 6-Oxygenated Estra-1, 3, 5 (10)-trienes and Related Compounds | |
| US3365473A (en) | 13beta-lower alkyl gona-4, 8(14)-dien-3-ones 17 beta process for the production thereof | |
| GB1383334A (en) | 15alpha,16alpha-methylene-steroids | |
| ALLEN Jr et al. | The synthesis of 16α-methoxyhydrocortisone acetate and congeners | |
| Masamune et al. | The synthesis of etiojervane analogues of cortisone | |
| Engel | STEROIDS AND RELATED PRODUCTS: VII. THE SYNTHESIS OF 17α-METHYLCORTICOSTERONE | |
| GB950390A (en) | 3ª,9ª-epoxy steroids of the androstane and pregnane series | |
| GB1260398A (en) | NEW 18-METHYL-5alpha-H-ANDROSTANES |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| EELA | Cancelled due to lapse of time |