NL8700397A - Zuivering van recombinant humaan-interleukine-1. - Google Patents

Zuivering van recombinant humaan-interleukine-1. Download PDF

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Publication number
NL8700397A
NL8700397A NL8700397A NL8700397A NL8700397A NL 8700397 A NL8700397 A NL 8700397A NL 8700397 A NL8700397 A NL 8700397A NL 8700397 A NL8700397 A NL 8700397A NL 8700397 A NL8700397 A NL 8700397A
Authority
NL
Netherlands
Prior art keywords
human interleukin
gradient
tris
interleukin
buffered
Prior art date
Application number
NL8700397A
Other languages
English (en)
Dutch (nl)
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of NL8700397A publication Critical patent/NL8700397A/nl

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/54Interleukins [IL]
    • C07K14/545IL-1
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/14Lymphokine; related peptides
    • Y10S930/141Interleukin

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Zoology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
NL8700397A 1986-02-18 1987-02-17 Zuivering van recombinant humaan-interleukine-1. NL8700397A (nl)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US83040686 1986-02-18
US06/830,406 US5831022A (en) 1986-02-18 1986-02-18 Purification of recombinant human IL-1α

Publications (1)

Publication Number Publication Date
NL8700397A true NL8700397A (nl) 1987-09-16

Family

ID=25256938

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8700397A NL8700397A (nl) 1986-02-18 1987-02-17 Zuivering van recombinant humaan-interleukine-1.

Country Status (10)

Country Link
US (1) US5831022A (da)
JP (1) JP2590085B2 (da)
BE (1) BE1000636A5 (da)
CH (1) CH676008A5 (da)
DE (1) DE3704868C2 (da)
DK (1) DK171419B1 (da)
FR (1) FR2595714B1 (da)
GB (1) GB2186580B (da)
IT (1) IT1202565B (da)
NL (1) NL8700397A (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU630341B2 (en) * 1987-12-18 1992-10-29 Immunex Corporation Topical wound-healing preparations comprising interleukin-1 proteins
US5120534A (en) * 1988-07-29 1992-06-09 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and medicament for treating thrombocytopenia
IT1226713B (it) * 1988-08-05 1991-02-05 Eniricerche Spa Procedimento per la preparazione di interleuchina 1 beta umana ricombinante in forma omogenea.
AU709586B2 (en) * 1994-10-24 1999-09-02 Ophidian Pharmaceuticals, Inc. Vaccine and antitoxin for treatment and prevention of C. difficile disease

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4401756A (en) * 1981-04-14 1983-08-30 Immunex Corporation Process for preparing human interleukin 2
CA1341562C (en) * 1982-03-31 2007-11-27 Tadatsugu Taniguchi Gene coded for interleukin-2 polypeptide, recombinant dna carrying the said gene, a living cell line possessing the recombinant dna, and method for producing interleukin-2 using the said cell
GR79124B (da) * 1982-12-22 1984-10-02 Genentech Inc
FR2550802B1 (fr) * 1983-08-17 1986-04-11 Inst Nat Sante Rech Med Procede de production d'interleukine 1 humaine et medicaments correspondants
CA1340853C (en) * 1983-12-23 1999-12-21 Hsiang-Fu Kung Purification of recombinant interleukin-2
JPS60149386A (ja) * 1984-01-17 1985-08-06 Dainippon Pharmaceut Co Ltd インタ−ロイキン1をコ−ドする伝令リボ核酸及びその調製法
JPS60197629A (ja) * 1984-03-16 1985-10-07 Chemo Sero Therapeut Res Inst HBs抗原の精製方法
DE3419995A1 (de) * 1984-05-29 1985-12-05 Hoechst Ag, 6230 Frankfurt Gentechnologisches verfahren zur herstellung von human-interleukin-2 und mittel zur durchfuehrung dieses verfahrens
CA1341433C (en) * 1984-06-19 2003-06-24 Douglas P. Cerretti Purification of interleukin 1
JPS617296A (ja) * 1984-06-19 1986-01-13 イミユネツクス、コ−ポレ−シヨン インタ−ロイキン1の遺伝子の精製、クロ−ニング及び特性づけ
DE3432196A1 (de) * 1984-09-01 1986-03-06 Boehringer Ingelheim International GmbH, 6507 Ingelheim Neues mechanisches aufschlussverfahren von bakterienzellen zur isolierung von rekombinant hergestellten peptiden
EP0200986B2 (en) * 1985-04-25 1998-03-11 F. Hoffmann-La Roche Ag Recombinant human interleukin-1
US4675387A (en) * 1985-07-26 1987-06-23 E. I. Du Pont De Nemours And Company Method for extracting protein with organic acid
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
US4801686A (en) * 1986-09-04 1989-01-31 Immunex Corporation Purification of recombinant interleukin-1

Also Published As

Publication number Publication date
US5831022A (en) 1998-11-03
BE1000636A5 (fr) 1989-02-28
IT1202565B (it) 1989-02-09
GB8703663D0 (en) 1987-03-25
GB2186580A (en) 1987-08-19
GB2186580B (en) 1990-08-22
IT8719420A0 (it) 1987-02-18
DK171419B1 (da) 1996-10-21
DK77387D0 (da) 1987-02-16
DE3704868C2 (de) 1995-09-21
DE3704868A1 (de) 1987-08-20
FR2595714A1 (fr) 1987-09-18
FR2595714B1 (fr) 1990-05-18
JPS62209097A (ja) 1987-09-14
CH676008A5 (da) 1990-11-30
JP2590085B2 (ja) 1997-03-12
DK77387A (da) 1987-08-19

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