FR2595714B1 - Procede perfectionne de production d'interleukine-0 - Google Patents

Procede perfectionne de production d'interleukine-0

Info

Publication number
FR2595714B1
FR2595714B1 FR878702010A FR8702010A FR2595714B1 FR 2595714 B1 FR2595714 B1 FR 2595714B1 FR 878702010 A FR878702010 A FR 878702010A FR 8702010 A FR8702010 A FR 8702010A FR 2595714 B1 FR2595714 B1 FR 2595714B1
Authority
FR
France
Prior art keywords
improved process
producing interleukin
interleukin
producing
improved
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR878702010A
Other languages
English (en)
Other versions
FR2595714A1 (fr
Inventor
Alvin Seth Stern
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of FR2595714A1 publication Critical patent/FR2595714A1/fr
Application granted granted Critical
Publication of FR2595714B1 publication Critical patent/FR2595714B1/fr
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/54—Interleukins [IL]
    • C07K14/545—IL-1
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00—Peptide or protein sequence
    • Y10S930/01—Peptide or protein sequence
    • Y10S930/14—Lymphokine; related peptides
    • Y10S930/141—Interleukin
FR878702010A 1986-02-18 1987-02-12 Procede perfectionne de production d'interleukine-0 Expired - Fee Related FR2595714B1 (fr)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/830,406 US5831022A (en) 1986-02-18 1986-02-18 Purification of recombinant human IL-1α

Publications (2)

Publication Number Publication Date
FR2595714A1 FR2595714A1 (fr) 1987-09-18
FR2595714B1 true FR2595714B1 (fr) 1990-05-18

Family

ID=25256938

Family Applications (1)

Application Number Title Priority Date Filing Date
FR878702010A Expired - Fee Related FR2595714B1 (fr) 1986-02-18 1987-02-12 Procede perfectionne de production d'interleukine-0

Country Status (10)

Country Link
US (1) US5831022A (fr)
JP (1) JP2590085B2 (fr)
BE (1) BE1000636A5 (fr)
CH (1) CH676008A5 (fr)
DE (1) DE3704868C2 (fr)
DK (1) DK171419B1 (fr)
FR (1) FR2595714B1 (fr)
GB (1) GB2186580B (fr)
IT (1) IT1202565B (fr)
NL (1) NL8700397A (fr)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0393140B1 (fr) * 1987-12-18 1993-08-11 Immunex Corporation Preparations de traitement topique de blessures contenant des proteines interleucines-1
KR960008010B1 (ko) * 1988-07-29 1996-06-19 오오쓰까세이야꾸 가부시끼가이샤 IL-1α 유도체 및 혈소판 감소증 치료 약제
IT1226713B (it) * 1988-08-05 1991-02-05 Eniricerche Spa Procedimento per la preparazione di interleuchina 1 beta umana ricombinante in forma omogenea.
NZ337543A (en) * 1994-10-24 2002-06-28 Allergan Inc Composition comprising avian antitoxin against clostridial neurotoxin protein and method for producing recombinant antitoxin proteins are provided for

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4401756A (en) * 1981-04-14 1983-08-30 Immunex Corporation Process for preparing human interleukin 2
CA1341562C (fr) * 1982-03-31 2007-11-27 Tadatsugu Taniguchi Gene codant pour un polypeptide ayant une activite interleukine 2, adn recombinant portant ledit gene, lignees cellulaires possedant ledit adn recombinant et procede pour la preparation d'interleukine 2 en utilisant lesdites cellules
GR79124B (fr) * 1982-12-22 1984-10-02 Genentech Inc
FR2550802B1 (fr) * 1983-08-17 1986-04-11 Inst Nat Sante Rech Med Procede de production d'interleukine 1 humaine et medicaments correspondants
CA1340853C (fr) * 1983-12-23 1999-12-21 Hsiang-Fu Kung Purification d'une interleukine-2 recombinante
JPS60149386A (ja) * 1984-01-17 1985-08-06 Dainippon Pharmaceut Co Ltd インタ−ロイキン１をコ−ドする伝令リボ核酸及びその調製法
JPS60197629A (ja) * 1984-03-16 1985-10-07 Chemo Sero Therapeut Res Inst ＨＢｓ抗原の精製方法
DE3419995A1 (de) * 1984-05-29 1985-12-05 Hoechst Ag, 6230 Frankfurt Gentechnologisches verfahren zur herstellung von human-interleukin-2 und mittel zur durchfuehrung dieses verfahrens
IE61353B1 (en) * 1984-06-19 1994-11-02 Immunex Corp Purified interleukin 1
JPS617296A (ja) * 1984-06-19 1986-01-13 イミユネツクス、コ−ポレ−シヨン インタ−ロイキン１の遺伝子の精製、クロ−ニング及び特性づけ
DE3432196A1 (de) * 1984-09-01 1986-03-06 Boehringer Ingelheim International GmbH, 6507 Ingelheim Neues mechanisches aufschlussverfahren von bakterienzellen zur isolierung von rekombinant hergestellten peptiden
EP0200986B2 (fr) * 1985-04-25 1998-03-11 F. Hoffmann-La Roche Ag Recombinant interleukine-1 humain
US4675387A (en) * 1985-07-26 1987-06-23 E. I. Du Pont De Nemours And Company Method for extracting protein with organic acid
US5008374A (en) * 1986-03-14 1991-04-16 Otsuka Pharmaceutical Co., Ltd. IL-1α derivatives and drugs
US4801686A (en) * 1986-09-04 1989-01-31 Immunex Corporation Purification of recombinant interleukin-1

Also Published As

Publication number Publication date
GB2186580B (en) 1990-08-22
NL8700397A (nl) 1987-09-16
IT1202565B (it) 1989-02-09
US5831022A (en) 1998-11-03
JP2590085B2 (ja) 1997-03-12
JPS62209097A (ja) 1987-09-14
CH676008A5 (fr) 1990-11-30
DK77387A (da) 1987-08-19
GB2186580A (en) 1987-08-19
DK171419B1 (da) 1996-10-21
IT8719420A0 (it) 1987-02-18
GB8703663D0 (en) 1987-03-25
DE3704868C2 (de) 1995-09-21
BE1000636A5 (fr) 1989-02-28
DK77387D0 (da) 1987-02-16
DE3704868A1 (de) 1987-08-20
FR2595714A1 (fr) 1987-09-18

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Legal Events

Date Code Title Description
TP Transmission of property
ST Notification of lapse