NL8302391A - Hulpstof voor antitumormiddelen. - Google Patents
Hulpstof voor antitumormiddelen. Download PDFInfo
- Publication number
- NL8302391A NL8302391A NL8302391A NL8302391A NL8302391A NL 8302391 A NL8302391 A NL 8302391A NL 8302391 A NL8302391 A NL 8302391A NL 8302391 A NL8302391 A NL 8302391A NL 8302391 A NL8302391 A NL 8302391A
- Authority
- NL
- Netherlands
- Prior art keywords
- radix
- parts
- excipient
- mitomycin
- group
- Prior art date
Links
- 239000002246 antineoplastic agent Substances 0.000 title description 5
- NWIBSHFKIJFRCO-WUDYKRTCSA-N Mytomycin Chemical compound C1N2C(C(C(C)=C(N)C3=O)=O)=C3[C@@H](COC(N)=O)[C@@]2(OC)[C@@H]2[C@H]1N2 NWIBSHFKIJFRCO-WUDYKRTCSA-N 0.000 claims description 71
- 229960004857 mitomycin Drugs 0.000 claims description 37
- 239000000546 pharmaceutical excipient Substances 0.000 claims description 35
- 230000000694 effects Effects 0.000 claims description 26
- 239000000284 extract Substances 0.000 claims description 23
- MWWSFMDVAYGXBV-RUELKSSGSA-N Doxorubicin hydrochloride Chemical compound Cl.O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 MWWSFMDVAYGXBV-RUELKSSGSA-N 0.000 claims description 18
- 229960002918 doxorubicin hydrochloride Drugs 0.000 claims description 18
- 239000003814 drug Substances 0.000 claims description 12
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 claims description 6
- 241001123050 Simplicia <grass> Species 0.000 claims description 6
- 230000000259 anti-tumor effect Effects 0.000 claims description 6
- 239000008989 cinnamomi cortex Substances 0.000 claims description 6
- 230000001965 increasing effect Effects 0.000 claims description 5
- 241000208340 Araliaceae Species 0.000 claims description 4
- 235000005035 Panax pseudoginseng ssp. pseudoginseng Nutrition 0.000 claims description 4
- 235000003140 Panax quinquefolius Nutrition 0.000 claims description 4
- 235000008434 ginseng Nutrition 0.000 claims description 4
- 230000037396 body weight Effects 0.000 description 12
- 201000002364 leukopenia Diseases 0.000 description 12
- 229940079593 drug Drugs 0.000 description 11
- 239000002671 adjuvant Substances 0.000 description 10
- 241000699670 Mus sp. Species 0.000 description 8
- 238000002474 experimental method Methods 0.000 description 8
- 239000003826 tablet Substances 0.000 description 8
- 231100001022 leukopenia Toxicity 0.000 description 7
- 239000000203 mixture Substances 0.000 description 7
- DDRJAANPRJIHGJ-UHFFFAOYSA-N creatinine Chemical compound CN1CC(=O)NC1=N DDRJAANPRJIHGJ-UHFFFAOYSA-N 0.000 description 6
- 210000000265 leukocyte Anatomy 0.000 description 6
- HQKMJHAJHXVSDF-UHFFFAOYSA-L magnesium stearate Chemical compound [Mg+2].CCCCCCCCCCCCCCCCCC([O-])=O.CCCCCCCCCCCCCCCCCC([O-])=O HQKMJHAJHXVSDF-UHFFFAOYSA-L 0.000 description 6
- 239000000843 powder Substances 0.000 description 5
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 description 5
- AOJJSUZBOXZQNB-TZSSRYMLSA-N Doxorubicin Chemical compound O([C@H]1C[C@@](O)(CC=2C(O)=C3C(=O)C=4C=CC=C(C=4C(=O)C3=C(O)C=21)OC)C(=O)CO)[C@H]1C[C@H](N)[C@H](O)[C@H](C)O1 AOJJSUZBOXZQNB-TZSSRYMLSA-N 0.000 description 4
- 239000008187 granular material Substances 0.000 description 4
- 238000011084 recovery Methods 0.000 description 4
- 238000001356 surgical procedure Methods 0.000 description 4
- 230000004083 survival effect Effects 0.000 description 4
- 108010088751 Albumins Proteins 0.000 description 3
- 102000009027 Albumins Human genes 0.000 description 3
- 108020004414 DNA Proteins 0.000 description 3
- 102000001554 Hemoglobins Human genes 0.000 description 3
- 108010054147 Hemoglobins Proteins 0.000 description 3
- 229930192392 Mitomycin Natural products 0.000 description 3
- 206010028980 Neoplasm Diseases 0.000 description 3
- 210000004369 blood Anatomy 0.000 description 3
- 239000008280 blood Substances 0.000 description 3
- 229940109239 creatinine Drugs 0.000 description 3
- 238000001035 drying Methods 0.000 description 3
- 239000003792 electrolyte Substances 0.000 description 3
- 210000003743 erythrocyte Anatomy 0.000 description 3
- 208000032839 leukemia Diseases 0.000 description 3
- 210000004698 lymphocyte Anatomy 0.000 description 3
- 235000019359 magnesium stearate Nutrition 0.000 description 3
- 239000000463 material Substances 0.000 description 3
- 239000003960 organic solvent Substances 0.000 description 3
- 238000002360 preparation method Methods 0.000 description 3
- 102000004169 proteins and genes Human genes 0.000 description 3
- 108090000623 proteins and genes Proteins 0.000 description 3
- 210000004881 tumor cell Anatomy 0.000 description 3
- 102000006395 Globulins Human genes 0.000 description 2
- 108010044091 Globulins Proteins 0.000 description 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-N Hydrochloric acid Chemical compound Cl VEXZGXHMUGYJMC-UHFFFAOYSA-N 0.000 description 2
- 230000007059 acute toxicity Effects 0.000 description 2
- 231100000403 acute toxicity Toxicity 0.000 description 2
- 201000011510 cancer Diseases 0.000 description 2
- 239000002775 capsule Substances 0.000 description 2
- 210000004027 cell Anatomy 0.000 description 2
- 239000001913 cellulose Substances 0.000 description 2
- 229920002678 cellulose Polymers 0.000 description 2
- 238000002648 combination therapy Methods 0.000 description 2
- 230000000052 comparative effect Effects 0.000 description 2
- 230000034994 death Effects 0.000 description 2
- 231100000517 death Toxicity 0.000 description 2
- 230000003247 decreasing effect Effects 0.000 description 2
- 229960004679 doxorubicin Drugs 0.000 description 2
- 238000000605 extraction Methods 0.000 description 2
- 230000002401 inhibitory effect Effects 0.000 description 2
- 230000009467 reduction Effects 0.000 description 2
- 231100000419 toxicity Toxicity 0.000 description 2
- 230000001988 toxicity Effects 0.000 description 2
- INGWEZCOABYORO-UHFFFAOYSA-N 2-(furan-2-yl)-7-methyl-1h-1,8-naphthyridin-4-one Chemical compound N=1C2=NC(C)=CC=C2C(O)=CC=1C1=CC=CO1 INGWEZCOABYORO-UHFFFAOYSA-N 0.000 description 1
- 108700020463 BRCA1 Proteins 0.000 description 1
- 102000036365 BRCA1 Human genes 0.000 description 1
- 102000006734 Beta-Globulins Human genes 0.000 description 1
- 108010087504 Beta-Globulins Proteins 0.000 description 1
- 208000017897 Carcinoma of esophagus Diseases 0.000 description 1
- 239000003390 Chinese drug Substances 0.000 description 1
- 208000000668 Chronic Pancreatitis Diseases 0.000 description 1
- 230000006820 DNA synthesis Effects 0.000 description 1
- 102000004163 DNA-directed RNA polymerases Human genes 0.000 description 1
- 108090000626 DNA-directed RNA polymerases Proteins 0.000 description 1
- 208000000461 Esophageal Neoplasms Diseases 0.000 description 1
- 241000202807 Glycyrrhiza Species 0.000 description 1
- DGAQECJNVWCQMB-PUAWFVPOSA-M Ilexoside XXIX Chemical compound C[C@@H]1CC[C@@]2(CC[C@@]3(C(=CC[C@H]4[C@]3(CC[C@@H]5[C@@]4(CC[C@@H](C5(C)C)OS(=O)(=O)[O-])C)C)[C@@H]2[C@]1(C)O)C)C(=O)O[C@H]6[C@@H]([C@H]([C@@H]([C@H](O6)CO)O)O)O.[Na+] DGAQECJNVWCQMB-PUAWFVPOSA-M 0.000 description 1
- GUBGYTABKSRVRQ-QKKXKWKRSA-N Lactose Natural products OC[C@H]1O[C@@H](O[C@H]2[C@H](O)[C@@H](O)C(O)O[C@@H]2CO)[C@H](O)[C@@H](O)[C@H]1O GUBGYTABKSRVRQ-QKKXKWKRSA-N 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 206010061902 Pancreatic neoplasm Diseases 0.000 description 1
- 206010033649 Pancreatitis chronic Diseases 0.000 description 1
- ZLMJMSJWJFRBEC-UHFFFAOYSA-N Potassium Chemical compound [K] ZLMJMSJWJFRBEC-UHFFFAOYSA-N 0.000 description 1
- 241000700159 Rattus Species 0.000 description 1
- 208000005718 Stomach Neoplasms Diseases 0.000 description 1
- 208000012886 Vertigo Diseases 0.000 description 1
- 244000154870 Viola adunca Species 0.000 description 1
- 235000005811 Viola adunca Nutrition 0.000 description 1
- 235000013487 Viola odorata Nutrition 0.000 description 1
- 235000002254 Viola papilionacea Nutrition 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000032823 cell division Effects 0.000 description 1
- 230000008859 change Effects 0.000 description 1
- 239000012829 chemotherapy agent Substances 0.000 description 1
- 238000004587 chromatography analysis Methods 0.000 description 1
- 230000007012 clinical effect Effects 0.000 description 1
- 239000011248 coating agent Substances 0.000 description 1
- 238000000576 coating method Methods 0.000 description 1
- 208000029742 colonic neoplasm Diseases 0.000 description 1
- 238000007796 conventional method Methods 0.000 description 1
- 239000013078 crystal Substances 0.000 description 1
- 238000000502 dialysis Methods 0.000 description 1
- 201000010099 disease Diseases 0.000 description 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 1
- 239000012153 distilled water Substances 0.000 description 1
- 238000009826 distribution Methods 0.000 description 1
- 238000002651 drug therapy Methods 0.000 description 1
- 230000002708 enhancing effect Effects 0.000 description 1
- 230000003203 everyday effect Effects 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 238000009472 formulation Methods 0.000 description 1
- 238000004108 freeze drying Methods 0.000 description 1
- 206010017758 gastric cancer Diseases 0.000 description 1
- 238000003304 gavage Methods 0.000 description 1
- 239000007902 hard capsule Substances 0.000 description 1
- 208000008384 ileus Diseases 0.000 description 1
- 230000001976 improved effect Effects 0.000 description 1
- LTINPJMVDKPJJI-UHFFFAOYSA-N iodinated glycerol Chemical compound CC(I)C1OCC(CO)O1 LTINPJMVDKPJJI-UHFFFAOYSA-N 0.000 description 1
- 239000009569 juzentaihoto Substances 0.000 description 1
- 239000008101 lactose Substances 0.000 description 1
- 230000003908 liver function Effects 0.000 description 1
- 239000007937 lozenge Substances 0.000 description 1
- 208000015486 malignant pancreatic neoplasm Diseases 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- FBBDOOHMGLLEGJ-UHFFFAOYSA-N methane;hydrochloride Chemical compound C.Cl FBBDOOHMGLLEGJ-UHFFFAOYSA-N 0.000 description 1
- 238000000034 method Methods 0.000 description 1
- 238000002156 mixing Methods 0.000 description 1
- 230000036651 mood Effects 0.000 description 1
- 201000001705 nipple carcinoma Diseases 0.000 description 1
- 201000002528 pancreatic cancer Diseases 0.000 description 1
- 208000008443 pancreatic carcinoma Diseases 0.000 description 1
- 239000002504 physiological saline solution Substances 0.000 description 1
- 230000002980 postoperative effect Effects 0.000 description 1
- 239000011591 potassium Substances 0.000 description 1
- 229910052700 potassium Inorganic materials 0.000 description 1
- 239000011734 sodium Substances 0.000 description 1
- 229910052708 sodium Inorganic materials 0.000 description 1
- 239000007921 spray Substances 0.000 description 1
- 238000001694 spray drying Methods 0.000 description 1
- 201000011549 stomach cancer Diseases 0.000 description 1
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- 230000035922 thirst Effects 0.000 description 1
- 206010043554 thrombocytopenia Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
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- 231100000889 vertigo Toxicity 0.000 description 1
- 230000004580 weight loss Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/234—Cnidium (snowparsley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/284—Atractylodes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/54—Lauraceae (Laurel family), e.g. cinnamon or sassafras
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/80—Scrophulariaceae (Figwort family)
- A61K36/804—Rehmannia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/02—Antidotes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Mycology (AREA)
- Biotechnology (AREA)
- Epidemiology (AREA)
- Botany (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Toxicology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Plant Substances (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP57144630A JPS5936619A (ja) | 1982-08-23 | 1982-08-23 | 制癌補助剤 |
| JP14463082 | 1982-08-23 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| NL8302391A true NL8302391A (nl) | 1984-03-16 |
Family
ID=15366509
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NL8302391A NL8302391A (nl) | 1982-08-23 | 1983-07-05 | Hulpstof voor antitumormiddelen. |
Country Status (10)
| Country | Link |
|---|---|
| US (1) | US4613591A (OSRAM) |
| JP (1) | JPS5936619A (OSRAM) |
| BE (1) | BE897403A (OSRAM) |
| CH (1) | CH659948A5 (OSRAM) |
| DE (1) | DE3328263C2 (OSRAM) |
| FR (1) | FR2531864B1 (OSRAM) |
| GB (1) | GB2126085B (OSRAM) |
| HU (1) | HU187103B (OSRAM) |
| IT (1) | IT1169771B (OSRAM) |
| NL (1) | NL8302391A (OSRAM) |
Families Citing this family (28)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4843067A (en) * | 1986-11-19 | 1989-06-27 | Yaguang Liu | Polysaccharide containing pharmaceutical composition for increasing the immune function |
| US4944946A (en) * | 1987-01-27 | 1990-07-31 | Yaguang Liu | Pharmaceutical composition for inhibiting viruses and increasing immune function (PII) |
| KR940000234B1 (ko) * | 1989-09-04 | 1994-01-12 | 김송배 | 신규 항암작용을 가지는 약학적 제제 및 제조방법 |
| JPH04215218A (ja) * | 1990-12-11 | 1992-08-06 | Fujitsu Ltd | キーボードスイッチ |
| JP2746532B2 (ja) * | 1994-02-23 | 1998-05-06 | 宮 和男 | イザリア型虫草を主成分とする免疫強化食品 |
| US5874084A (en) * | 1996-07-19 | 1999-02-23 | Yng-Wong; Quing Non | Using complex herbal formulations to treat hot flashes |
| US20010006686A1 (en) * | 1999-03-19 | 2001-07-05 | David G. Corley | Inflammatory mediation obtained from atractylodes lancea |
| US20010024664A1 (en) * | 1999-03-19 | 2001-09-27 | Obukowicz Mark G. | Selective COX-2 inhibition from edible plant extracts |
| CA2378402C (en) * | 1999-07-09 | 2014-04-08 | Sun Farm Corporation | Method of treating malignancies and viral infections and improving immune function with a dietary supplement |
| DK1401458T3 (da) * | 2000-03-09 | 2011-05-09 | Univ Yale | Sammensætning bestående af PHY906 og kemoterapeutiske midler |
| WO2008101079A1 (en) | 2007-02-15 | 2008-08-21 | Yale University | Herbal-composition phy906 and its use in chemotherapy |
| WO2009152228A2 (en) | 2008-06-10 | 2009-12-17 | Yale University | Use of the combination of phy906 and a tyrosine kinase inhibitor as a cancer treatment regimen |
| JP2004517838A (ja) * | 2000-12-15 | 2004-06-17 | ファルマシア・コーポレーション | 非食用植物抽出物による選択的ｃｏｘ−２阻害 |
| AU2002229074A1 (en) * | 2000-12-15 | 2002-06-24 | Pharmacia Corporation | Selective cox-2 inhibition from plant extracts |
| KR100406902B1 (ko) * | 2001-02-20 | 2003-11-21 | 홍종수 | 외상 치료 활성을 갖는 생약 추출물 및 이를 함유하는 건강식품 또는 동물용 사료 |
| CN1326554C (zh) * | 2001-04-02 | 2007-07-18 | 李洪芬 | 一种抗肿瘤药 |
| US20040126438A1 (en) * | 2001-12-13 | 2004-07-01 | Obukowicz Mark G. | Selective cox-2 inhibition from plant extracts |
| US20040062823A1 (en) * | 2001-12-13 | 2004-04-01 | Obukowicz Mark G. | Selective cox-2 inhibition from non-edible plant extracts |
| TW562937B (en) * | 2002-03-26 | 2003-11-21 | Nanya Technology Corp | Method for fast determining defect type of word line |
| CN1241598C (zh) * | 2002-05-14 | 2006-02-15 | 朱建中 | 一种治疗牙周病的中药制剂、制备方法及应用 |
| US6790464B2 (en) * | 2003-01-16 | 2004-09-14 | Healthaid Enterprise Pte. Ltd. | Herbal compositions for prostate conditions |
| US7569234B2 (en) * | 2003-12-19 | 2009-08-04 | Ming Qi Oncology Chinese Medicines, Inc. | Herb composition for treating lung cancer and preparation method thereof |
| JP4781771B2 (ja) * | 2004-10-08 | 2011-09-28 | 財團法人佛教慈濟総合醫院 | ガン治療用の当帰抽出物 |
| DE202005015707U1 (de) * | 2005-10-06 | 2006-04-20 | Sheng Foong Pharmaceutical Co. Ltd., Su-Ao Chen | Kräuterzusammensetzung zur Behandlung von Krebs |
| JP2007016053A (ja) * | 2006-10-23 | 2007-01-25 | Pola Chem Ind Inc | 抗悪性腫瘍剤 |
| EP2703001A1 (en) * | 2012-08-26 | 2014-03-05 | XAX Kft. | Tumor vaccination |
| CN103169778B (zh) * | 2013-03-12 | 2015-07-22 | 张成全 | 一种治疗肺癌的药物组合物及其制备方法 |
| CN112040965B (zh) * | 2018-02-28 | 2023-04-14 | 中央大学校产学协力团 | 用于预防、减轻或治疗恶病质和肌肉损失的组合物 |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1445831A (en) * | 1972-08-22 | 1976-08-11 | Boissevain L R | Pharmaceutically active derivatives of glycyrrhizinic acid and their preparation |
| DE2828851A1 (de) * | 1978-06-30 | 1980-01-10 | Shigeru Arichi | Neue antitumormittel |
| US4323562A (en) * | 1979-07-27 | 1982-04-06 | Kim Dae Eun | Adjuvant for stimulating production of lymphocytes |
| US4361697A (en) * | 1981-05-21 | 1982-11-30 | F. K. Suzuki International, Inc. | Extraction, separation and recovery of diterpene glycosides from Stevia rebaudiana plants |
-
1982
- 1982-08-23 JP JP57144630A patent/JPS5936619A/ja active Granted
-
1983
- 1983-06-14 HU HU832112A patent/HU187103B/hu not_active IP Right Cessation
- 1983-06-29 US US06/509,197 patent/US4613591A/en not_active Expired - Fee Related
- 1983-07-05 NL NL8302391A patent/NL8302391A/nl not_active Application Discontinuation
- 1983-07-28 BE BE0/211256A patent/BE897403A/fr not_active IP Right Cessation
- 1983-08-04 DE DE3328263A patent/DE3328263C2/de not_active Expired
- 1983-08-19 FR FR8313492A patent/FR2531864B1/fr not_active Expired
- 1983-08-22 CH CH4571/83A patent/CH659948A5/de not_active IP Right Cessation
- 1983-08-23 IT IT22616/83A patent/IT1169771B/it active
- 1983-08-23 GB GB08322663A patent/GB2126085B/en not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| GB2126085B (en) | 1986-08-13 |
| US4613591A (en) | 1986-09-23 |
| CH659948A5 (de) | 1987-03-13 |
| JPH0256329B2 (OSRAM) | 1990-11-29 |
| HU187103B (en) | 1985-11-28 |
| IT1169771B (it) | 1987-06-03 |
| BE897403A (fr) | 1983-11-14 |
| GB2126085A (en) | 1984-03-21 |
| DE3328263A1 (de) | 1984-02-23 |
| JPS5936619A (ja) | 1984-02-28 |
| FR2531864A1 (fr) | 1984-02-24 |
| IT8322616A0 (it) | 1983-08-23 |
| GB8322663D0 (en) | 1983-09-28 |
| FR2531864B1 (fr) | 1986-06-27 |
| DE3328263C2 (de) | 1986-06-26 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1B | A search report has been drawn up | ||
| A85 | Still pending on 85-01-01 | ||
| BC | A request for examination has been filed | ||
| BV | The patent application has lapsed |