NL8001752A - 4-amino-3-chinolinecarbonzuren en hun esters als antimaagzuur- en antimaagzweerverbinding. - Google Patents

4-amino-3-chinolinecarbonzuren en hun esters als antimaagzuur- en antimaagzweerverbinding. Download PDF

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Publication number
NL8001752A
NL8001752A NL8001752A NL8001752A NL8001752A NL 8001752 A NL8001752 A NL 8001752A NL 8001752 A NL8001752 A NL 8001752A NL 8001752 A NL8001752 A NL 8001752A NL 8001752 A NL8001752 A NL 8001752A
Authority
NL
Netherlands
Prior art keywords
ethyl
alkyl
methoxy
quinolinecarboxylate
amino
Prior art date
Application number
NL8001752A
Other languages
English (en)
Dutch (nl)
Original Assignee
Robins Co Inc A H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Robins Co Inc A H filed Critical Robins Co Inc A H
Publication of NL8001752A publication Critical patent/NL8001752A/nl

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
    • C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
    • C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
    • C07D215/54—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 3
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Quinoline Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
NL8001752A 1979-03-26 1980-03-25 4-amino-3-chinolinecarbonzuren en hun esters als antimaagzuur- en antimaagzweerverbinding. NL8001752A (nl)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US2398179A 1979-03-26 1979-03-26
US2398179 1979-03-26
US06/127,153 US4343804A (en) 1979-03-26 1980-03-04 4-Amino-3-quinolinecarboxylic acids and esters-antisecretory anti-ulcer compounds
US12715380 1980-03-04

Publications (1)

Publication Number Publication Date
NL8001752A true NL8001752A (nl) 1980-09-30

Family

ID=26697875

Family Applications (1)

Application Number Title Priority Date Filing Date
NL8001752A NL8001752A (nl) 1979-03-26 1980-03-25 4-amino-3-chinolinecarbonzuren en hun esters als antimaagzuur- en antimaagzweerverbinding.

Country Status (31)

Country Link
US (1) US4343804A (cs)
JP (1) JPH02117663A (cs)
AR (1) AR230268A1 (cs)
AT (1) AT372373B (cs)
AU (1) AU528388B2 (cs)
BR (1) BR8001779A (cs)
CA (1) CA1147338A (cs)
CH (1) CH644105A5 (cs)
DE (1) DE3011490A1 (cs)
DK (1) DK156056C (cs)
EG (1) EG15009A (cs)
ES (1) ES8103048A1 (cs)
FI (1) FI77452C (cs)
FR (1) FR2452485B1 (cs)
GB (1) GB2047244B (cs)
GR (1) GR68006B (cs)
HK (1) HK67983A (cs)
IE (1) IE49577B1 (cs)
IL (1) IL59628A (cs)
IN (1) IN151446B (cs)
IT (1) IT1133079B (cs)
MX (1) MX6264E (cs)
NL (1) NL8001752A (cs)
NO (1) NO153927C (cs)
NZ (1) NZ193252A (cs)
PH (1) PH16416A (cs)
PL (1) PL125030B1 (cs)
PT (1) PT71008B (cs)
SE (1) SE435837B (cs)
SG (1) SG33683G (cs)
YU (1) YU41702B (cs)

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GB8610981D0 (en) * 1986-05-06 1986-06-11 Ici America Inc Quinoline amides
GB8621425D0 (en) * 1986-09-05 1986-10-15 Smith Kline French Lab Compounds
GB8804447D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804446D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804444D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804448D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804443D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
GB8804445D0 (en) * 1988-02-25 1988-03-23 Smithkline Beckman Intercredit Compounds
US5432182A (en) * 1989-02-23 1995-07-11 Smithkline Beecham Intercredit B.V. Compounds substituted quinoline derivatives
CA2011086A1 (en) * 1989-03-17 1990-09-17 Karl-Heinz Geiss 2-alkyl-4-arylmethylaminoquinolines, the use thereof and drugs prepared therefrom
DE3917233A1 (de) * 1989-05-26 1990-11-29 Basf Ag 8-substituierte 4-(heterocyclylmethylamino)-chinoline, ihre verwendung und daraus hergestellte arzneimittel
GB8918265D0 (en) * 1989-08-10 1989-09-20 Smithkline Beckman Intercredit Compounds
US5362743A (en) * 1993-03-09 1994-11-08 Pfizer Inc. Aminoquinoline derivatives
IS4164A (is) * 1993-06-11 1994-12-12 Ab Astra Efnasambönd sem hindra flæði magasýru
US5556863A (en) * 1993-06-11 1996-09-17 Astra Aktiebolag Compound for gastric acid secretion inhibition
HU222178B1 (hu) * 1993-08-10 2003-04-28 James Black Foundation Ltd. Gasztrin és CCK-receptor ligandumok, eljárás előállításukra és ezeket tartalmazó gyógyászati készítmények
US5650415A (en) * 1995-06-07 1997-07-22 Sugen, Inc. Quinoline compounds
KR0169813B1 (ko) * 1995-07-12 1999-01-15 김종인 4-아미노-3-아실나프티리딘 유도체
US5760041A (en) * 1996-02-05 1998-06-02 American Cyanamid Company 4-aminoquinazoline EGFR Inhibitors
US6875769B2 (en) * 1996-05-23 2005-04-05 Pfizer Inc. Substituted6,6-hetero-bicyclicderivatives
US5929080A (en) * 1997-05-06 1999-07-27 American Cyanamid Company Method of treating polycystic kidney disease
US6251912B1 (en) 1997-08-01 2001-06-26 American Cyanamid Company Substituted quinazoline derivatives
US6323209B1 (en) 1997-11-06 2001-11-27 American Cyanamid Company Method of treating or inhibiting colonic polyps
EP1950201A1 (en) 1998-09-29 2008-07-30 Wyeth Holdings Corporation Substituted 3-cyanoquinolines as protein tyrosine kinases inhibitors
KR100641802B1 (ko) * 1999-12-28 2006-11-02 에자이 가부시키가이샤 술폰아미드 함유 복소환 화합물
US6521618B2 (en) 2000-03-28 2003-02-18 Wyeth 3-cyanoquinolines, 3-cyano-1,6-naphthyridines, and 3-cyano-1,7-naphthyridines as protein kinase inhibitors
US6576644B2 (en) * 2000-09-06 2003-06-10 Bristol-Myers Squibb Co. Quinoline inhibitors of cGMP phosphodiesterase
UA80393C2 (uk) 2000-12-07 2007-09-25 Алтана Фарма Аг Фармацевтична композиція, яка містить інгібітор фде 4, диспергований в матриці
MY140561A (en) 2002-02-20 2009-12-31 Nycomed Gmbh Dosage form containing pde 4 inhibitor as active ingredient
ES2295816T3 (es) 2003-01-14 2008-04-16 Arena Pharmaceuticals, Inc. Derivados arilo y heteroarilo 1,2,3-trisustituidos como moduladores del metabolismo, y profilaxis y tratamiento de transtornos relacionados con los mismos, tales como la diabetes y la hiperglucemia.
BRPI0406427B8 (pt) 2003-03-10 2021-05-25 Astrazeneca Ab processo para a preparação de roflumilast
JP4920410B2 (ja) * 2003-07-14 2012-04-18 アリーナ ファーマシューティカルズ， インコーポレイテッド 代謝モジュレーターとしての縮合アリールおよびヘテロアリール誘導体ならびに代謝に関連する障害の予防および治療
US8663694B2 (en) * 2005-03-16 2014-03-04 Takeda Gmbh Taste masked dosage form containing roflumilast
WO2011022216A1 (en) * 2009-08-17 2011-02-24 High Point Pharmaceuticals, Llc Substituted pyridine derivatives, pharmaceutical compositions, and methods of use to treat oxidative stress
JP5856980B2 (ja) 2010-01-27 2016-02-10 アリーナ ファーマシューティカルズ， インコーポレイテッド （Ｒ）−２−（７−（４−シクロペンチル−３−（トリフルオロメチル）ベンジルオキシ）−１，２，３，４−テトラヒドロシクロペンタ［ｂ］インドール−３−イル）酢酸およびその塩の調製のためのプロセス
WO2012040279A1 (en) 2010-09-22 2012-03-29 Arena Pharmaceuticals, Inc. Modulators of the gpr119 receptor and the treatment of disorders related thereto
MX386419B (es) 2015-01-06 2025-03-18 Arena Pharm Inc Metodos de condiciones de tratamiento relacionadas con el receptor s1p1.
EP3310760B8 (en) 2015-06-22 2022-10-19 Arena Pharmaceuticals, Inc. Crystalline l-arginine salt of (r)-2-(7-(4-cyclopentyl-3-(trifluoromethyl)benzyloxy)-1,2,3,4-tetrahydrocyclo-penta[b]indol-3-yl)acetic acid for use in s1p1 receptor-associated disorders
PT3538512T (pt) 2016-11-11 2021-08-16 Bayer Animal Health Gmbh Novos derivados de quinolina-3-carboxamida anti-helmínticos
AU2018220521A1 (en) 2017-02-16 2019-09-05 Arena Pharmaceuticals, Inc. Compounds and methods for treatment of primary biliary cholangitis
WO2019084271A1 (en) * 2017-10-25 2019-05-02 Children's Medical Center Corporation PAPD5 INHIBITORS AND METHODS OF USE
PT3790874T (pt) 2018-05-09 2023-05-31 Bayer Animal Health Gmbh Derivados de quinolina antelmínticos
ES2987794T3 (es) 2018-06-06 2024-11-18 Arena Pharm Inc Procedimientos de tratamiento de afecciones relacionadas con el receptor S1P1

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3470186A (en) * 1967-06-02 1969-09-30 American Cyanamid Co Substituted 4-anilino-3-quinolinecarboxylic acids and esters
JPS4838712A (cs) * 1971-09-18 1973-06-07

Also Published As

Publication number Publication date
AT372373B (de) 1983-09-26
IE800605L (en) 1980-09-26
IL59628A (en) 1983-06-15
DE3011490A1 (de) 1981-03-12
BR8001779A (pt) 1980-11-18
AU528388B2 (en) 1983-04-28
JPH02117663A (ja) 1990-05-02
SE8002292L (sv) 1980-09-27
PH16416A (en) 1983-09-29
DK156056C (da) 1989-11-06
FR2452485A1 (fr) 1980-10-24
GB2047244A (en) 1980-11-26
ATA156480A (de) 1983-02-15
AU5684880A (en) 1980-10-02
DK156056B (da) 1989-06-19
AR230268A1 (es) 1984-03-01
IE49577B1 (en) 1985-10-30
IT1133079B (it) 1986-07-09
GR68006B (cs) 1981-10-26
FI77452C (fi) 1989-03-10
NO153927B (no) 1986-03-10
NO153927C (no) 1986-06-18
PL222993A1 (cs) 1981-01-30
CH644105A5 (fr) 1984-07-13
IN151446B (cs) 1983-04-23
US4343804A (en) 1982-08-10
SE435837B (sv) 1984-10-22
PT71008A (en) 1980-04-01
YU41702B (en) 1987-12-31
ES489887A0 (es) 1981-02-16
IT8067465A0 (it) 1980-03-26
MX6264E (es) 1985-02-19
NO800858L (no) 1980-09-29
DE3011490C2 (cs) 1988-12-22
PT71008B (en) 1981-06-25
FR2452485B1 (fr) 1986-09-12
DK128380A (da) 1980-09-27
FI800910A7 (fi) 1980-09-27
FI77452B (fi) 1988-11-30
SG33683G (en) 1985-03-29
NZ193252A (en) 1984-04-27
YU84480A (en) 1983-10-31
EG15009A (en) 1985-03-31
IL59628A0 (en) 1980-06-30
ES8103048A1 (es) 1981-02-16
CA1147338A (en) 1983-05-31
PL125030B1 (en) 1983-03-31
HK67983A (en) 1983-12-23
GB2047244B (en) 1983-02-23

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Legal Events

Date Code Title Description
A85 Still pending on 85-01-01
BA A request for search or an international-type search has been filed
BB A search report has been drawn up
BC A request for examination has been filed
BV The patent application has lapsed