NL192880B - Nucleïnezuur dat voor het oppervlakte-antigeen van een Hepatitis B virus codeert, peptide waarvoor het codeert, vector die het nucleïnezuur bevat , hybride-eiwit waarvoor het in de vector ingevoegde nucleïnezuur codeert, en vaccin dat het hybride-eiwit bevat. - Google Patents
Nucleïnezuur dat voor het oppervlakte-antigeen van een Hepatitis B virus codeert, peptide waarvoor het codeert, vector die het nucleïnezuur bevat , hybride-eiwit waarvoor het in de vector ingevoegde nucleïnezuur codeert, en vaccin dat het hybride-eiwit bevat.Info
- Publication number
- NL192880B NL192880B NL8020315A NL8020315A NL192880B NL 192880 B NL192880 B NL 192880B NL 8020315 A NL8020315 A NL 8020315A NL 8020315 A NL8020315 A NL 8020315A NL 192880 B NL192880 B NL 192880B
- Authority
- NL
- Netherlands
- Prior art keywords
- nucleic acid
- encoding
- hybrid protein
- vector
- hepatitis
- Prior art date
Links
- 108020004707 nucleic acids Proteins 0.000 title 3
- 102000039446 nucleic acids Human genes 0.000 title 3
- 150000007523 nucleic acids Chemical class 0.000 title 3
- 108090000623 proteins and genes Proteins 0.000 title 2
- 102000004169 proteins and genes Human genes 0.000 title 2
- 241000700721 Hepatitis B virus Species 0.000 title 1
- 239000000427 antigen Substances 0.000 title 1
- 102000036639 antigens Human genes 0.000 title 1
- 108091007433 antigens Proteins 0.000 title 1
- 108090000765 processed proteins & peptides Proteins 0.000 title 1
- 229960005486 vaccine Drugs 0.000 title 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
- A61K39/12—Viral antigens
- A61K39/29—Hepatitis virus
- A61K39/292—Serum hepatitis virus, hepatitis B virus, e.g. Australia antigen
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P21/00—Preparation of peptides or proteins
- C12P21/02—Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
- C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
- C12Q1/70—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving virus or bacteriophage
- C12Q1/701—Specific hybridization probes
- C12Q1/706—Specific hybridization probes for hepatitis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K39/00—Medicinal preparations containing antigens or antibodies
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2710/00—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA dsDNA viruses
- C12N2710/00011—Details
- C12N2710/10011—Adenoviridae
- C12N2710/10111—Atadenovirus, e.g. ovine adenovirus D
- C12N2710/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2730/00—Reverse transcribing DNA viruses
- C12N2730/00011—Details
- C12N2730/10011—Hepadnaviridae
- C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
- C12N2730/10134—Use of virus or viral component as vaccine, e.g. live-attenuated or inactivated virus, VLP, viral protein
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/808—Materials and products related to genetic engineering or hybrid or fused cell technology, e.g. hybridoma, monoclonal products
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
- Y10S530/82—Proteins from microorganisms
- Y10S530/826—Viruses
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S930/00—Peptide or protein sequence
- Y10S930/01—Peptide or protein sequence
- Y10S930/22—Viral peptide or viral protein
- Y10S930/223—Hepatitis related
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Virology (AREA)
- Zoology (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- General Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Medicinal Chemistry (AREA)
- Biophysics (AREA)
- Epidemiology (AREA)
- Communicable Diseases (AREA)
- Physics & Mathematics (AREA)
- Public Health (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Mycology (AREA)
- Plant Pathology (AREA)
- Gastroenterology & Hepatology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Applications Claiming Priority (6)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR7921811 | 1979-08-30 | ||
FR7921811A FR2464269B1 (fr) | 1979-08-30 | 1979-08-30 | Sequence nucleotidique codant l'antigene de surface du virus de l'hepatite b, procede permettant son obtention et antigene obtenu |
FR8009039A FR2480779B2 (fr) | 1979-08-30 | 1980-04-22 | Vecteur contenant une sequence nucleotidique de l'antigene de surface du virus de l'hepatite b et procede de fabrication d'une molecule immunogene mettant en oeuvre ce vecteur |
FR8009039 | 1980-04-22 | ||
FR8000133 | 1980-08-29 | ||
PCT/FR1980/000133 WO1981000577A1 (fr) | 1979-08-30 | 1980-08-29 | Sequence nucleotidique codant l'antigene de surface du virus de l'hepatite b, vecteur contenant ladite sequence nucleotidique, procede permettant son obtention et antigene obtenu |
Publications (3)
Publication Number | Publication Date |
---|---|
NL8020315A NL8020315A (nl) | 1981-07-01 |
NL192880B true NL192880B (nl) | 1997-12-01 |
NL192880C NL192880C (nl) | 1998-04-02 |
Family
ID=26221334
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
NL8020315A NL192880C (nl) | 1979-08-30 | 1980-08-29 | Nucleïnezuur dat voor het oppervlakte-antigeen van een Hepatitis B virus codeert, peptide waarvoor het codeert, vector die het nucleïnezuur bevat , hybride-eiwit waarvoor het in de vector ingevoegde nucleïnezuur codeert, en vaccin dat het hybride-eiwit bevat. |
Country Status (12)
Country | Link |
---|---|
US (1) | US4428941A (nl) |
JP (1) | JPS6362198B2 (nl) |
BE (1) | BE884988A (nl) |
CA (1) | CA1163585A (nl) |
CH (1) | CH663796A5 (nl) |
DE (1) | DE3049831C2 (nl) |
FR (1) | FR2480779B2 (nl) |
GB (1) | GB2070621B (nl) |
LU (1) | LU88365I2 (nl) |
NL (1) | NL192880C (nl) |
SE (3) | SE8102726L (nl) |
WO (1) | WO1981000577A1 (nl) |
Families Citing this family (76)
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US6416996B1 (en) * | 1978-12-18 | 2002-07-09 | Institut Pasteur | Nucleotide sequence comprising the genome of hepatitis b virus, nucleotide sequence coding the surface antigen of the hepatitis b virus, vectors containing the nucleotide sequences, process for the preparation thereof, and antigen obtained thereby |
ES487106A0 (es) * | 1978-12-22 | 1981-05-16 | Biogen Nv | Un metodo para producir al menos un polipeptido que muestra antigenicidad de hbv |
EP0182442B2 (en) * | 1978-12-22 | 1996-04-03 | Biogen, Inc. | Recombinant DNA molecules and their method of production |
US6297355B1 (en) | 1978-12-22 | 2001-10-02 | Biogen, Inc. | Polypeptides displaying HBV antigenicity or hbv antigen specificity |
US5196194A (en) * | 1979-05-24 | 1993-03-23 | The Regents Of The University Of California | Vaccines containing Hepatitis B S-protein |
IE52036B1 (en) * | 1979-05-24 | 1987-05-27 | Univ California | Non-passageable viruses |
USRE34705E (en) * | 1979-08-30 | 1994-08-23 | Institut Pasteur | Nucleotidic sequence coding the surface antigen of the hepatitis B virus, vector containing said nucleotidic sequence, process allowing the obtention thereof and antigen obtained thereby |
EP0038765B1 (fr) * | 1980-04-22 | 1987-09-02 | Institut Pasteur | Vaccin contre l'hépatite virale B, procédé et cellules eucaryotes transformées pour la production de ce vaccin |
NZ199722A (en) * | 1981-02-25 | 1985-12-13 | Genentech Inc | Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain |
US4769238A (en) | 1981-08-04 | 1988-09-06 | The Regents Of The University Of California | Synthesis of human virus antigens by yeast |
ZW18282A1 (en) * | 1981-08-31 | 1983-03-23 | Genentech Inc | Preparation of polypeptides in vertebrate cell culture |
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US4593002A (en) * | 1982-01-11 | 1986-06-03 | Salk Institute Biotechnology/Industrial Associates, Inc. | Viruses with recombinant surface proteins |
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US4820642A (en) * | 1983-04-04 | 1989-04-11 | The Regents Of The University Of California | Amplified expression vector |
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US5324513A (en) * | 1984-03-07 | 1994-06-28 | Institut Pasteur | Composition useful for the fabrication of vaccines |
US4861588A (en) * | 1985-02-05 | 1989-08-29 | New York Blood Center, Inc. | Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers |
US5204096A (en) * | 1984-03-07 | 1993-04-20 | New York Blood Center, Inc. | Pre-S gene coded peptide hepatitis B immunogens, vaccines, diagnostics, and synthetic lipid vesicle carriers |
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US4599230A (en) * | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
WO1985004103A1 (en) * | 1984-03-09 | 1985-09-26 | Scripps Clinic And Research Foundation | Synthetic hepatitis b virus vaccine including both t cell anc b cell determinants |
SU1470739A1 (ru) * | 1984-07-16 | 1989-04-07 | Всесоюзный кардиологический научный центр АМН СССР | Гексапептид, обладающий гепатопротективным действием |
US4743553A (en) * | 1984-07-18 | 1988-05-10 | W. R. Grace & Co. | Synthetic genes for bovine parainfluenza virus |
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JPH0745514B2 (ja) * | 1985-08-20 | 1995-05-17 | 武田薬品工業株式会社 | 新規蛋白質およびその製造法 |
US4895800A (en) * | 1985-11-26 | 1990-01-23 | Phillips Petroleum Company | Yeast production of hepatitis B surface antigen |
WO1987007896A1 (en) * | 1986-06-20 | 1987-12-30 | Scripps Clinic And Research Foundation | T and b cell epitopes of the pre-s region of hepatitis b virus surface antigen |
US4778784A (en) * | 1987-01-07 | 1988-10-18 | Baylor College Of Medicine | Cyclic peptide and method of use for inducing an immunological response to hepatitis B virus |
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US5162226A (en) | 1987-08-24 | 1992-11-10 | University Of Tennessee Research Corp. (U.T.R.C.) | Therapeutic compositions against streptococcal infections, transformed hosts, methods of immunization and genetically engineered products |
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US8007805B2 (en) * | 2003-08-08 | 2011-08-30 | Paladin Labs, Inc. | Chimeric antigens for breaking host tolerance to foreign antigens |
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US8492114B2 (en) | 2008-01-25 | 2013-07-23 | Battelle Energy Alliance, Llc | Methods of combined bioprocessing and related microorganisms, thermophilic and/or acidophilic enzymes, and nucleic acids encoding said enzymes |
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Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
YU257278A (en) * | 1977-11-08 | 1984-02-29 | Genentech Inc | Process for obtaining a recombinat clone carrier |
FR2422685A1 (fr) * | 1978-04-14 | 1979-11-09 | Pasteur Institut | Vecteurs, derives du bacteriophage lambda, permettant l'insertion et l'expression d'un gene, procaryote ou eucaryote, sous le controle du promoteur et de l'operateur de l'operon lactose de la bacterie escherichia coli |
FR2428075A1 (fr) * | 1978-06-08 | 1980-01-04 | Pasteur Institut | Procede de production de proteines par expression des genes correspondants dans des bacteries et vecteurs susceptibles d'etre mis en oeuvre dans de tels procedes |
FR2444713A1 (fr) * | 1978-12-18 | 1980-07-18 | Pasteur Institut | Procede de production d'un adn comprenant le genome du virus de l'hepatite b et vecteur le comportant |
ES487106A0 (es) * | 1978-12-22 | 1981-05-16 | Biogen Nv | Un metodo para producir al menos un polipeptido que muestra antigenicidad de hbv |
IE52036B1 (en) * | 1979-05-24 | 1987-05-27 | Univ California | Non-passageable viruses |
-
1980
- 1980-04-22 FR FR8009039A patent/FR2480779B2/fr not_active Expired
- 1980-08-29 GB GB8113283A patent/GB2070621B/en not_active Expired
- 1980-08-29 CA CA000359303A patent/CA1163585A/fr not_active Expired
- 1980-08-29 BE BE0/201915A patent/BE884988A/fr not_active IP Right Cessation
- 1980-08-29 JP JP55501975A patent/JPS6362198B2/ja not_active Expired
- 1980-08-29 WO PCT/FR1980/000133 patent/WO1981000577A1/fr active Application Filing
- 1980-08-29 NL NL8020315A patent/NL192880C/nl not_active IP Right Cessation
- 1980-08-29 CH CH2854/81A patent/CH663796A5/fr not_active IP Right Cessation
- 1980-08-29 US US06/261,199 patent/US4428941A/en not_active Ceased
- 1980-08-29 DE DE19803049831 patent/DE3049831C2/de not_active Expired - Lifetime
-
1981
- 1981-04-29 SE SE8102726D patent/SE8102726L/xx not_active Application Discontinuation
- 1981-04-29 SE SE8102726A patent/SE463459B/sv not_active IP Right Cessation
-
1983
- 1983-06-16 SE SE8303463A patent/SE462530B/sv not_active IP Right Cessation
-
1993
- 1993-07-02 LU LU88365C patent/LU88365I2/fr unknown
Also Published As
Publication number | Publication date |
---|---|
US4428941A (en) | 1984-01-31 |
SE462530B (sv) | 1990-07-09 |
SE8303463L (sv) | 1983-06-16 |
GB2070621B (en) | 1983-05-18 |
SE460727B (sv) | 1989-11-13 |
DE3049831T1 (nl) | 1982-06-16 |
NL192880C (nl) | 1998-04-02 |
CA1163585A (fr) | 1984-03-13 |
JPS6362198B2 (nl) | 1988-12-01 |
FR2480779A2 (fr) | 1981-10-23 |
LU88365I2 (fr) | 1994-05-04 |
WO1981000577A1 (fr) | 1981-03-05 |
SE8303463D0 (sv) | 1983-06-16 |
CH663796A5 (fr) | 1988-01-15 |
SE8102726L (sv) | 1981-04-29 |
JPS56501128A (nl) | 1981-08-13 |
FR2480779B2 (fr) | 1986-07-18 |
BE884988A (fr) | 1981-03-02 |
GB2070621A (en) | 1981-09-09 |
NL8020315A (nl) | 1981-07-01 |
SE463459B (sv) | 1990-11-26 |
DE3049831C2 (de) | 1992-08-27 |
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Legal Events
Date | Code | Title | Description |
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A85 | Still pending on 85-01-01 | ||
BA | A request for search or an international-type search has been filed | ||
BB | A search report has been drawn up | ||
BC | A request for examination has been filed | ||
V4 | Discontinued because of reaching the maximum lifetime of a patent |
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