NL187912C - Farmaceutisch preparaat dat een carbostyrilderivaat bevat, alsmede carbostyrilderivaat, gesubstitueerd door een (1-piperidyl)alkoxygroep. - Google Patents
Farmaceutisch preparaat dat een carbostyrilderivaat bevat, alsmede carbostyrilderivaat, gesubstitueerd door een (1-piperidyl)alkoxygroep.Info
- Publication number
- NL187912C NL187912C NLAANVRAGE8005188,A NL8005188A NL187912C NL 187912 C NL187912 C NL 187912C NL 8005188 A NL8005188 A NL 8005188A NL 187912 C NL187912 C NL 187912C
- Authority
- NL
- Netherlands
- Prior art keywords
- carbostyril derivative
- piperidyl
- alkoxy group
- pharmaceutical preparation
- preparation containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/20—Oxygen atoms
- C07D215/22—Oxygen atoms attached in position 2 or 4
- C07D215/227—Oxygen atoms attached in position 2 or 4 only one oxygen atom which is attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/08—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms
- C07D211/10—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms
- C07D211/14—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hydrocarbon or substituted hydrocarbon radicals directly attached to ring carbon atoms with radicals containing only carbon and hydrogen atoms attached to ring carbon atoms with hydrocarbon or substituted hydrocarbon radicals attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
- C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D211/06—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members
- C07D211/36—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having no double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D211/40—Oxygen atoms
- C07D211/44—Oxygen atoms attached in position 4
- C07D211/52—Oxygen atoms attached in position 4 having an aryl radical as the second substituent in position 4
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Pulmonology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP12045279A JPS5643280A (en) | 1979-09-18 | 1979-09-18 | Carbostyril derivative |
| JP12045279 | 1979-09-18 | ||
| JP12556579 | 1979-09-28 | ||
| JP12556579A JPS5649360A (en) | 1979-09-28 | 1979-09-28 | 2-oxoquinoline derivative |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| NL8005188A NL8005188A (nl) | 1981-03-20 |
| NL187912B NL187912B (nl) | 1991-09-16 |
| NL187912C true NL187912C (nl) | 1992-02-17 |
Family
ID=26458032
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| NLAANVRAGE8005188,A NL187912C (nl) | 1979-09-18 | 1980-09-17 | Farmaceutisch preparaat dat een carbostyrilderivaat bevat, alsmede carbostyrilderivaat, gesubstitueerd door een (1-piperidyl)alkoxygroep. |
Country Status (19)
| Country | Link |
|---|---|
| US (1) | US4482560A (no) |
| AR (2) | AR230280A1 (no) |
| AT (1) | AT376972B (no) |
| AU (1) | AU518144B2 (no) |
| CA (1) | CA1151172A (no) |
| CH (1) | CH645892A5 (no) |
| DE (1) | DE3034237A1 (no) |
| DK (1) | DK158984C (no) |
| ES (1) | ES495163A0 (no) |
| FI (1) | FI76322C (no) |
| FR (1) | FR2465732A1 (no) |
| GB (1) | GB2063869B (no) |
| IT (1) | IT1129263B (no) |
| MX (1) | MX6806E (no) |
| NL (1) | NL187912C (no) |
| NO (1) | NO154841C (no) |
| PT (1) | PT71810B (no) |
| SE (1) | SE439632B (no) |
| SU (1) | SU1091857A3 (no) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE2901336A1 (de) | 1979-01-15 | 1980-07-24 | Boehringer Mannheim Gmbh | Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
| CH655110A5 (de) * | 1982-09-03 | 1986-03-27 | Otsuka Pharma Co Ltd | Carbostyrilderivate, verfahren zu deren herstellung und arzneimittel, welche diese enthalten. |
| GB8426584D0 (en) * | 1984-10-19 | 1984-11-28 | Beecham Group Plc | Compounds |
| US4704390A (en) * | 1986-02-13 | 1987-11-03 | Warner-Lambert Company | Phenyl and heterocyclic tetrahydropyridyl alkoxy-benzheterocyclic compounds as antipsychotic agents |
| US4921862A (en) * | 1986-05-29 | 1990-05-01 | Syntex (U.S.A.) Inc. | Carbostyril derivatives as combined thromboxane synthetase and cyclic-amp phosphodiesterase inhibitors |
| US4792561A (en) * | 1986-05-29 | 1988-12-20 | Syntex (U.S.A.) Inc. | Carbostyril derivatives as combined thromboxane synthetase and cyclic-AMP phosphodiesterase inhibitors |
| EP0255134B1 (en) * | 1986-07-31 | 1993-03-03 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivatives and salts thereof, process for preparing them, and cardiotonic composition containing same |
| FR2620704B1 (fr) * | 1987-09-17 | 1991-04-26 | Sanofi Sa | Derives de (benzyl-4 piperidino)-1 propanol-2, leur preparation, leur utilisation comme antimicrobiens et les produits les contenant |
| US5227381A (en) * | 1988-05-02 | 1993-07-13 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril derivative |
| US5082847A (en) * | 1990-07-18 | 1992-01-21 | Syntex (U.S.A.) Inc. | Carbostyril compounds connected via an oxyalkyl group with a piperidine ring and having pharmaceutical utility |
| JP2686887B2 (ja) * | 1992-08-11 | 1997-12-08 | キッセイ薬品工業株式会社 | ピペリジノ−３，４−ジヒドロカルボスチリル誘導体 |
| IT1264816B1 (it) * | 1993-07-28 | 1996-10-10 | Pergam Srl | Procedimento per la preparazione di derivati del procedimento per la preparazione di derivati del 3,4-diidrocarbostirile 3,4-diidrocarbostirile |
| ZA9610745B (en) * | 1995-12-22 | 1997-06-24 | Warner Lambert Co | 4-Subsituted piperidine analogs and their use as subtype selective nmda receptor antagonists |
| ZA9610738B (en) | 1995-12-22 | 1997-06-24 | Warner Lambert Co | Subtype selective nmda receptor ligands and the use thereof |
| ZA9610736B (en) * | 1995-12-22 | 1997-06-27 | Warner Lambert Co | 2-Substituted piperidine analogs and their use as subtypeselective nmda receptor antagonists |
| EP1283199A4 (en) | 2000-05-16 | 2003-12-17 | Takeda Chemical Industries Ltd | MELANIN CONCENTRATION HORMONE ANTAGONIST |
| DE60302139T3 (de) † | 2003-01-09 | 2011-02-24 | Otsuka Pharmaceutical Co., Ltd. | Verfahren zur herstellung von aripiprazole |
| DE102008022221A1 (de) | 2008-05-06 | 2009-11-12 | Universität des Saarlandes | Inhibitoren der humanen Aldosteronsynthase CYP11B2 |
| US8541404B2 (en) | 2009-11-09 | 2013-09-24 | Elexopharm Gmbh | Inhibitors of the human aldosterone synthase CYP11B2 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3629266A (en) * | 1969-03-03 | 1971-12-21 | Miles Lab | (phenyl piperidino alkyl)3 4-dihydrocarbostyrils |
| US3910924A (en) * | 1972-04-13 | 1975-10-07 | Otsuka Pharma Co Ltd | 3,4-Dihydrocarbostyril derivatives and a process for preparing the same |
| JPS48103590A (no) * | 1972-04-13 | 1973-12-25 | ||
| US4256890A (en) * | 1972-09-14 | 1981-03-17 | Otsukapharmaceutical Co., Ltd. | 3,4-Dihydrocarbostyril derivatives and process for producing the same |
| JPS5239035B2 (no) * | 1972-12-14 | 1977-10-03 | ||
| JPS5310986B2 (no) * | 1974-02-05 | 1978-04-18 | ||
| JPS5310989B2 (no) * | 1974-04-25 | 1978-04-18 | ||
| US3994900A (en) * | 1976-01-23 | 1976-11-30 | E. R. Squibb & Sons, Inc. | 6-(Or 8)-[[(substituted amino)alkyl]oxy(or thio)]-3,4-dihydro-4-phenyl-2(1H)-quinolinones |
| JPS5919541B2 (ja) * | 1976-03-17 | 1984-05-07 | 大塚製薬株式会社 | 新規３，４−ジヒドロカルボスチリル誘導体 |
| CH619453A5 (no) * | 1976-03-17 | 1980-09-30 | Otsuka Pharma Co Ltd | |
| US4210753A (en) * | 1976-03-17 | 1980-07-01 | Otsuka Pharmaceutical Co., Ltd. | Carbostyril compounds |
| JPS609501B2 (ja) * | 1976-05-07 | 1985-03-11 | 大塚製薬株式会社 | 新規３，４−ジヒドロカルボスチリル誘導体 |
| DE2719562C2 (de) * | 1976-05-08 | 1986-05-07 | Otsuka Pharmaceutical Co. Ltd., Tokio/Tokyo | 3, 4-Dihydrocarbostyrilderivate, Verfahren zu deren Herstellung und Arzneimittel, welche diese enthalten |
| JPS6019295B2 (ja) * | 1977-03-04 | 1985-05-15 | 大塚製薬株式会社 | カルボスチリル誘導体及びその製造法 |
| JPS5416478A (en) * | 1977-07-08 | 1979-02-07 | Otsuka Pharmaceut Co Ltd | 3,4-dihydrocarbostyril herivative |
| JPS54130587A (en) * | 1978-03-30 | 1979-10-09 | Otsuka Pharmaceut Co Ltd | Carbostyryl derivative |
| DE2827566A1 (de) * | 1978-06-23 | 1980-01-10 | Boehringer Mannheim Gmbh | 1,2-dihydro-chinolin-2-on-derivate und verfahren zu ihrer herstellung |
| JPS5589221A (en) * | 1978-12-28 | 1980-07-05 | Otsuka Pharmaceut Co Ltd | Antihistaminic agent |
| JPS5589222A (en) * | 1978-12-28 | 1980-07-05 | Otsuka Pharmaceut Co Ltd | Antihistaminic agent |
| DE2901336A1 (de) * | 1979-01-15 | 1980-07-24 | Boehringer Mannheim Gmbh | Neue arylether, verfahren zu deren herstellung sowie diese verbindungen enthaltende arzneimittel |
-
1980
- 1980-09-11 DE DE19803034237 patent/DE3034237A1/de active Granted
- 1980-09-12 AU AU62381/80A patent/AU518144B2/en not_active Ceased
- 1980-09-12 FR FR8019708A patent/FR2465732A1/fr active Granted
- 1980-09-16 FI FI802905A patent/FI76322C/fi not_active IP Right Cessation
- 1980-09-16 SU SU802982853A patent/SU1091857A3/ru active
- 1980-09-17 CA CA000360402A patent/CA1151172A/en not_active Expired
- 1980-09-17 CH CH694080A patent/CH645892A5/de not_active IP Right Cessation
- 1980-09-17 NO NO802762A patent/NO154841C/no unknown
- 1980-09-17 AR AR282565A patent/AR230280A1/es active
- 1980-09-17 NL NLAANVRAGE8005188,A patent/NL187912C/xx not_active IP Right Cessation
- 1980-09-17 SE SE8006498A patent/SE439632B/sv not_active IP Right Cessation
- 1980-09-17 AT AT0465780A patent/AT376972B/de not_active IP Right Cessation
- 1980-09-17 DK DK394080A patent/DK158984C/da active
- 1980-09-17 PT PT71810A patent/PT71810B/pt unknown
- 1980-09-18 ES ES495163A patent/ES495163A0/es active Granted
- 1980-09-18 GB GB8030207A patent/GB2063869B/en not_active Expired
- 1980-09-18 MX MX809034U patent/MX6806E/es unknown
- 1980-09-18 IT IT68445/80A patent/IT1129263B/it active
-
1982
- 1982-03-12 US US06/357,769 patent/US4482560A/en not_active Expired - Fee Related
- 1982-05-18 AR AR289431A patent/AR230059A1/es active
Also Published As
| Publication number | Publication date |
|---|---|
| FI76322C (fi) | 1988-10-10 |
| US4482560A (en) | 1984-11-13 |
| AR230280A1 (es) | 1984-03-01 |
| SE439632B (sv) | 1985-06-24 |
| CH645892A5 (de) | 1984-10-31 |
| FR2465732B1 (no) | 1983-06-24 |
| NL8005188A (nl) | 1981-03-20 |
| MX6806E (es) | 1986-07-30 |
| DE3034237A1 (de) | 1981-04-16 |
| ES8200679A1 (es) | 1981-11-16 |
| GB2063869A (en) | 1981-06-10 |
| NO802762L (no) | 1981-03-19 |
| AR230059A1 (es) | 1984-02-29 |
| DK158984B (da) | 1990-08-13 |
| SU1091857A3 (ru) | 1984-05-07 |
| AU518144B2 (en) | 1981-09-17 |
| GB2063869B (en) | 1983-05-25 |
| NO154841B (no) | 1986-09-22 |
| AU6238180A (en) | 1981-05-28 |
| NO154841C (no) | 1987-01-07 |
| SE8006498L (sv) | 1981-03-19 |
| IT1129263B (it) | 1986-06-04 |
| IT8068445A0 (it) | 1980-09-18 |
| FR2465732A1 (fr) | 1981-03-27 |
| PT71810A (en) | 1980-10-01 |
| FI802905A (fi) | 1981-03-19 |
| DE3034237C2 (no) | 1988-04-21 |
| FI76322B (fi) | 1988-06-30 |
| ES495163A0 (es) | 1981-11-16 |
| NL187912B (nl) | 1991-09-16 |
| PT71810B (en) | 1981-07-07 |
| CA1151172A (en) | 1983-08-02 |
| AT376972B (de) | 1985-01-25 |
| ATA465780A (de) | 1984-06-15 |
| DK158984C (da) | 1991-01-14 |
| DK394080A (da) | 1981-03-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| A1A | A request for search or an international-type search has been filed | ||
| BB | A search report has been drawn up | ||
| BC | A request for examination has been filed | ||
| A85 | Still pending on 85-01-01 | ||
| V1 | Lapsed because of non-payment of the annual fee |