MY157344A - 2-aza-bicyclo[3.1.0]hexane derivatives as orexin receptor antogonists - Google Patents

2-aza-bicyclo[3.1.0]hexane derivatives as orexin receptor antogonists

Info

Publication number
MY157344A
MY157344A MYPI20092751A MYPI20092751A MY157344A MY 157344 A MY157344 A MY 157344A MY PI20092751 A MYPI20092751 A MY PI20092751A MY PI20092751 A MYPI20092751 A MY PI20092751A MY 157344 A MY157344 A MY 157344A
Authority
MY
Malaysia
Prior art keywords
aza
bicyclo
orexin receptor
hexane derivatives
receptor antogonists
Prior art date
Application number
MYPI20092751A
Other languages
English (en)
Inventor
Assaoui Hamed
Boss Christoph
Gude Markus
Koberstein Ralf
Sifferlen Thierry
Original Assignee
Actelion Pharmaceutical Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Actelion Pharmaceutical Ltd filed Critical Actelion Pharmaceutical Ltd
Publication of MY157344A publication Critical patent/MY157344A/en

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    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems
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    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
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    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Obesity (AREA)
  • Endocrinology (AREA)
  • Pulmonology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Addiction (AREA)
  • Rheumatology (AREA)
  • Psychology (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Immunology (AREA)
  • Vascular Medicine (AREA)
  • Dermatology (AREA)
  • Otolaryngology (AREA)
MYPI20092751A 2006-12-28 2007-12-28 2-aza-bicyclo[3.1.0]hexane derivatives as orexin receptor antogonists MY157344A (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
IB2006055042 2006-12-28

Publications (1)

Publication Number Publication Date
MY157344A true MY157344A (en) 2016-05-31

Family

ID=39343649

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI20092751A MY157344A (en) 2006-12-28 2007-12-28 2-aza-bicyclo[3.1.0]hexane derivatives as orexin receptor antogonists

Country Status (28)

Country Link
US (1) US8288435B2 (cg-RX-API-DMAC7.html)
EP (1) EP2094690B1 (cg-RX-API-DMAC7.html)
JP (1) JP2010514751A (cg-RX-API-DMAC7.html)
KR (1) KR20090094168A (cg-RX-API-DMAC7.html)
CN (1) CN101568536B (cg-RX-API-DMAC7.html)
AR (1) AR064561A1 (cg-RX-API-DMAC7.html)
AT (1) ATE505467T1 (cg-RX-API-DMAC7.html)
AU (1) AU2007340944B2 (cg-RX-API-DMAC7.html)
BR (1) BRPI0720876A2 (cg-RX-API-DMAC7.html)
CA (1) CA2669821A1 (cg-RX-API-DMAC7.html)
CL (1) CL2007003827A1 (cg-RX-API-DMAC7.html)
CY (1) CY1111705T1 (cg-RX-API-DMAC7.html)
DE (1) DE602007013937D1 (cg-RX-API-DMAC7.html)
DK (1) DK2094690T3 (cg-RX-API-DMAC7.html)
ES (1) ES2364297T3 (cg-RX-API-DMAC7.html)
HR (1) HRP20110509T1 (cg-RX-API-DMAC7.html)
MA (1) MA31000B1 (cg-RX-API-DMAC7.html)
MX (1) MX2009006860A (cg-RX-API-DMAC7.html)
MY (1) MY157344A (cg-RX-API-DMAC7.html)
NO (1) NO20092762L (cg-RX-API-DMAC7.html)
NZ (1) NZ578642A (cg-RX-API-DMAC7.html)
PL (1) PL2094690T3 (cg-RX-API-DMAC7.html)
PT (1) PT2094690E (cg-RX-API-DMAC7.html)
RU (1) RU2460732C2 (cg-RX-API-DMAC7.html)
SI (1) SI2094690T1 (cg-RX-API-DMAC7.html)
TW (1) TW200833328A (cg-RX-API-DMAC7.html)
WO (1) WO2008081399A2 (cg-RX-API-DMAC7.html)
ZA (1) ZA200905229B (cg-RX-API-DMAC7.html)

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CA2669060A1 (en) 2006-12-01 2008-06-05 Actelion Pharmaceuticals Ltd Piperidine compounds
CL2008000836A1 (es) * 2007-03-26 2008-11-07 Actelion Pharmaceuticals Ltd Compuestos derivados de tiazolidina, antagonistas del receptor de orexina; composicion farmaceutica que los comprende; y su uso en el tratamiento de neurosis emocional, depresion grave, trastornos psicoticos, alzheimer, parkinson, dolor, entre otras.
CA2687230A1 (en) 2007-05-23 2008-12-11 Merck & Co., Inc. Cyclopropyl pyrrolidine orexin receptor antagonists
WO2009040730A2 (en) * 2007-09-24 2009-04-02 Actelion Pharmaceuticals Ltd Pyrrolidines and piperidines as orexin receptor antagonists
EP2247586B1 (en) * 2008-02-21 2012-04-25 Actelion Pharmaceuticals Ltd. 2-aza-bicyclo[2.2.1]heptane derivatives
CN102015645B (zh) * 2008-04-30 2012-11-14 埃科特莱茵药品有限公司 哌啶和吡咯烷化合物
RU2011119217A (ru) * 2008-10-14 2012-11-27 Актелион Фармасьютикалз Лтд Производные фенетиламида и их гетероциклические аналоги
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ITMI20120424A1 (it) * 2012-03-19 2013-09-20 Rottapharm Spa Composti chimici
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